Cell And Molecular Biology Of The Ear
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Cell And Molecular Biology Of The Ear
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Author : David J. Lim
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Cell And Molecular Biology Of The Ear written by David J. Lim and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
Dr. Howard House, founder of the House Ear Institute and House Ear Clinic often uses the analogy of planting a seed when referring to establishing the House Ear Institute in 1946. Two grateful patients of Dr. House put forth the idea that his knowledge and innovative skills could be used to expand the understanding of hearing impairment and its treatment. Those two early patients provided the "seed money" to begin the Institute. Since that time, the growth has been phenomenal from a one-man laboratory to a multidisciplinary facility boasting over 175 scien tists, physicians, and support staff, all dedicated to the advancement of otologic research and education. Six years ago after a half-century of remarkable success with prosthetic and device research, the Institute began cultivating a new field of endeavor-cell and molecular biology. Don Nielsen, then the Institute's Executive Vice President for Research and Scientific Director, began exploring the potential for hair cell regen eration and presented his ideas to the Board of Trustees. For a period of six months, we did a lot of fact finding to assess what role the Institute might take in this excit ing new field.
Development Of Auditory And Vestibular Systems 3 Molecular Development Of The Inner Ear
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Author : Raymond Romand
language : en
Publisher: Academic Press
Release Date : 2003-12-10
Development Of Auditory And Vestibular Systems 3 Molecular Development Of The Inner Ear written by Raymond Romand and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-10 with Science categories.
Thanks to advances in genetics and genomics, research on inner ear development has flourished. Better approaches and experimental models have shed light on the function of a variety of vertebrate genes and their related proteins. This latest volume of Current Topics in Developmental Biology delves into this new research to show how the discovery of more genes involved in the development of the inner ear leads to the generation of new models that examine a wealth of issues -- from the origins of human deafness to the roles of genes during inner ear induction, development and differentiation. The wide variety of experimental approaches will help readers to understand the broad range of issues related to inner ear morphogenesis and other concepts from complementary areas of investigation. This state-of-the-art overview will be essential reading for researchers, clinicians and students alike. * Scores of high-quality, full- color figures * Detailed schemes on the structure and timing of ear development * Current Topics in Developmental Biology is the longest-running forum for contemporary issues in developmental biology
Development Of The Inner Ear
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Author : Matthew Kelley
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-03-04
Development Of The Inner Ear written by Matthew Kelley and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-04 with Science categories.
The Springer Handbook of Auditory Research presents a series of compreh- sive and synthetic reviews of the fundamental topics in modern auditory - search. The volumes are aimed at all individuals with interests in hearing research including advanced graduate students, postdoctoral researchers, and clinical investigators. The volumes are intended to introduce new investigators to important aspects of hearing science and to help established investigators to betterunderstandthefundamentaltheoriesanddatain?eldsofhearingthatthey may not normally follow closely. Each volume presents a particular topic comprehensively, and each servesas a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in peer-reviewed journals. The volumes focus on topics that have developed a solid data and conceptual foundation rather than on those for which a literature is only beginning to develop. New research areas will be covered on a timely basis in the series as they begin to mature. Eachvolumeintheseriesconsistsofafewsubstantialchaptersonaparticular topic. In some cases, the topics will be ones of traditional interest for which there is a substantial body of data and theory, such as auditory neuroanatomy (Vol. 1) and neurophysiology (Vol. 2). Other volumes in the series deal with topics that have begun to mature more recently, suchasdevelopment,plasticity, and computational models of neural processing. In many cases, the series - itorsarejoinedbyaco-editorhavingspecialexpertiseinthetopicofthevolume.
Handbook Of Mouse Auditory Research
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Author : James F. Willott
language : en
Publisher: CRC Press
Release Date : 2001-05-23
Handbook Of Mouse Auditory Research written by James F. Willott and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-05-23 with Medical categories.
This unique compilation of chapters reviews a broad range of topics at the cutting edge of hearing research. The authors include many of the top auditory scientists in the world as well as some of the brightest rising stars. Although the book obviously focuses on the exciting, revolutionary work being done with mice, the authors have made a strong
Mechanotransduction Of The Hair Cell
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Author : Wei Xiong
language : en
Publisher: Springer
Release Date : 2018-04-27
Mechanotransduction Of The Hair Cell written by Wei Xiong and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-27 with Medical categories.
This book summarizes the emerging experimental evidence on hair-cell mechanotransduction, and covers hair’s cellular structure, biophysical properties, molecular components and functions. Auditory hair cells convert sound-induced vibration into electrical signals. This biological process, mechanotransduction, is what allows us to hear and communicate in our daily lives. However, our grasp of hair-cell mechanotransduction is still far from complete. Recent advances in molecular genetics and biophysics have helped us gain deeper insights into this process, especially the molecular constituent and operation of the channel complex. This book provides a cutting-edge snapshot for all readers who are interested in or studying how auditory hair cells detect sound.
Genes Hearing And Deafness
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Author : Alessandro Martini
language : en
Publisher: CRC Press
Release Date : 2007-06-13
Genes Hearing And Deafness written by Alessandro Martini and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-13 with Medical categories.
The field of generic hearing impairment is one where rapid advances are taking place, and it can often be difficult for Audiologists to keep track of the broader picture. In this important new text the authors take a synoptic approach and summarize the causes and basis of hearing impairments, the impact on the individual and the therapies available
Auditory Mechanisms Processes And Models Proceedings Of The Ninth International Symposium With Cd Rom
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Author : Alfred L Nuttall
language : en
Publisher: World Scientific
Release Date : 2006-08-10
Auditory Mechanisms Processes And Models Proceedings Of The Ninth International Symposium With Cd Rom written by Alfred L Nuttall and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-08-10 with Medical categories.
The workshop brought together experts in genetics, molecular and cellular biology, physiology, engineering, physics, mathematics, audiology and medicine to present current work and to review the critical issues of inner ear function. A special emphasis of the workshop was on analytical model based studies. Experimentalists and theoreticians thus shared their points of view. The topics ranged from consideration of the hearing organ as a system to the study and modeling of individual auditory cells including molecular aspects of function. Some of the topics in the book are: motor proteins in hair cells; mechanical and electrical aspects of transduction by motor proteins; function of proteins in stereocilia of hair cells; production of acoustic force by stereocilia, mechanical properties of hair cells and the organ of Corti; mechanical vibration of the organ of Corti; wave propagation in tissue and fluids of the inner ear; sound amplification in the cochlea; critical oscillations; cochlear nonlinearity, and mechanisms for the production of otoacoustic emissions. This book will be invaluable to researchers and students in auditory science.
Concepts And Challenges In The Biophysics Of Hearing With Cd Rom Proceedings Of The 10th International Workshop On The Mechanics Of Hearing
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Author : Nigel P Cooper
language : en
Publisher: World Scientific
Release Date : 2009-02-12
Concepts And Challenges In The Biophysics Of Hearing With Cd Rom Proceedings Of The 10th International Workshop On The Mechanics Of Hearing written by Nigel P Cooper and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-12 with Science categories.
This book extends our understanding of the mechanics and biophysics of hearing by bringing together the latest research on the topic by experts in cell and molecular biology, physiology, physics, engineering and mathematics. It contains the proceedings of the 10th International Workshop on the Mechanics of Hearing that was held at Keele University in the United Kingdom at the end of July, 2008. Topics for discussion included theoretical and experimental research at the molecular, cellular and systems levels. Separate sections of the book deal with: the transmission of sound energy to and from the inner ear, and wave propagation within the inner ear; the enhancement of stimulus wave motion that occurs in the inner ear; new measurement techniques that will underpin future innovative studies; the micro-mechanics of the basilar and tectorial membranes and the organ of Corti; cochlear dynamics; sensory hair cells and electromechanical transduction; and sensory hair-bundles and mechano-electrical transduction. The book concludes with the transcript of an open discussion session between the participants of the workshop, highlighting areas of uncertainty and controversy in the field, and pointing the way to the solutions to be sought in future research. This book reviews and synthesizes current concepts and challenges in the biophysics of hearing, and will be an invaluable guide to researchers and students in all branches of auditory science.
Vertebrate Hair Cells
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Author : Ruth Eatock
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-07-01
Vertebrate Hair Cells written by Ruth Eatock and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-01 with Science categories.
The Springer Handbook of Auditory Research presents a series of compreh- sive and synthetic reviews of the fundamental topics in modern auditory - search. The volumes are aimed at all individuals with interests in hearing research including advanced graduate students, postdoctoral researchers, and clinical investigators. The volumes are intended to introduce new investigators to important aspects of hearing science and to help established investigators to better understand the fundamental theories and data in ?elds of hearing that they may not normally follow closely. Each volume presents a particular topic comprehensively, and each serves as a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in peer-reviewed journals. The volumes focus on topics that have developed a solid data and conceptual foundation rather than on those for which a literature is only beginning to develop. New research areas will be covered on a timely basis in the series as they begin to mature.
Molecular Signaling Of Mammalian Inner Ear Development
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Author : Dorothy A. Frenz
language : en
Publisher:
Release Date : 2013
Molecular Signaling Of Mammalian Inner Ear Development written by Dorothy A. Frenz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
The inner ear originates from an ectodermal thickening, the otic placode, which lies adjacent to the developing hindbrain. Complex interactions between regulatory signaling molecules guide development of the simple otic placode into the elaborate, multifunctional organs of hearing and balance. This book delves into recent research in the field, focusing on successive stages of inner ear development and how they are influenced by the coordinate activity of signaling molecules. This book begins with an overview of the evolutionary adaptation of the organ of Corti (organ of hearing) and the molecular signals that characterize ancestral development of the inner ear. Following this, the topics addressed include the complex signaling interactions underlying induction of the otic placode, key molecular mediators influencing inner ear development and patterning, genetic signaling of the vestibular (balance) system and clinical correlations to human balance disorders, commitment to auditory hair cell fate, and reliance of the inner ear on retinoic acid, a biologically-active derivative of vitamin A, for appropriate development. This timely and comprehensive book provides an excellent resource for researchers, clinician-scientists and students alike.