Mechanotransduction Of The Hair Cell


Mechanotransduction Of The Hair Cell
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Mechanotransduction Of The Hair Cell


Mechanotransduction Of The Hair Cell
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Author : Wei Xiong
language : en
Publisher: Springer
Release Date : 2018-04-27

Mechanotransduction Of The Hair Cell written by Wei Xiong and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-27 with Medical categories.


This book summarizes the emerging experimental evidence on hair-cell mechanotransduction, and covers hair’s cellular structure, biophysical properties, molecular components and functions. Auditory hair cells convert sound-induced vibration into electrical signals. This biological process, mechanotransduction, is what allows us to hear and communicate in our daily lives. However, our grasp of hair-cell mechanotransduction is still far from complete. Recent advances in molecular genetics and biophysics have helped us gain deeper insights into this process, especially the molecular constituent and operation of the channel complex. This book provides a cutting-edge snapshot for all readers who are interested in or studying how auditory hair cells detect sound.



Vertebrate Hair Cells


Vertebrate Hair Cells
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Author : Ruth Eatock
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-07-01

Vertebrate Hair Cells written by Ruth Eatock and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-01 with Science categories.


The Springer Handbook of Auditory Research presents a series of compreh- sive and synthetic reviews of the fundamental topics in modern auditory - search. The volumes are aimed at all individuals with interests in hearing research including advanced graduate students, postdoctoral researchers, and clinical investigators. The volumes are intended to introduce new investigators to important aspects of hearing science and to help established investigators to better understand the fundamental theories and data in ?elds of hearing that they may not normally follow closely. Each volume presents a particular topic comprehensively, and each serves as a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in peer-reviewed journals. The volumes focus on topics that have developed a solid data and conceptual foundation rather than on those for which a literature is only beginning to develop. New research areas will be covered on a timely basis in the series as they begin to mature.



Hair Cells Regeneration Repair And Death


Hair Cells Regeneration Repair And Death
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Author : Jacob Evans
language : en
Publisher: States Academic Press
Release Date : 2021-11-16

Hair Cells Regeneration Repair And Death written by Jacob Evans and has been published by States Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-16 with Medical categories.


The sensory receptors which belong to the vestibular and auditory systems of vertebrates are termed as hair cells. They are present within the ears. These cells are able to detect movement around them through mechanotransduction. In mammals, hair cells are located in the cochlea of the inner ear. These cells can be categorized into two types, the inner and outer hair cells. They are functionally and anatomically different from each other. The inner hair cells are responsible for converting the sound vibrations in the fluids of the cochlea into electrical signals which are then conveyed to the brain. They are unable to regenerate. Therefore, any injury or damage to them is permanent and can lead to a decrease in hearing sensitivity. This book covers in detail some existent theories and innovative concepts revolving around the regeneration, repair and death of hair cells. Its aim is to present researches that have transformed this discipline and aided its advancement. This book will help the readers in keeping pace with the rapid changes in this field.



Understanding The Cochlea


Understanding The Cochlea
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Author : Geoffrey A. Manley
language : en
Publisher: Springer
Release Date : 2017-08-30

Understanding The Cochlea written by Geoffrey A. Manley and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-30 with Medical categories.


This SHAR volume serves to expand, supplement, and update the original "Cochlea" volume in the series. The book aims to highlight the power of diverse modern approaches in cochlear research by focusing on advances in those fields over the last two decades. It also provides insights into where cochlear research is going, including new hearing prostheses for the deaf that will most likely soon enter the phase of clinical trials. The book will appeal to a broad, interdisciplinary readership, including neuroscientists and clinicians in addition to the more specific auditory community.



Evolutionary Genetics Of Fishes


Evolutionary Genetics Of Fishes
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Author : Bruce Turner
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Evolutionary Genetics Of Fishes written by Bruce Turner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


It is my hope that this collection of reviews can be profitably read by all who are interested in evolutionary biology. However, I would like to specifically target it for two disparate groups of biologists seldom men tioned in the same sentence, classical ichthyologists and molecular biologists. Since classical times, and perhaps even before, ichthyologists have stood in awe at the tremendous diversity of fishes. The bulk of effort in the field has always been directed toward understanding this diversity, i. e. , extracting from it a coherent picture of evolutionary processes and lineages. This effort has, in turn, always been overwhelmingly based upon morphological comparisons. The practical advantages of such compari sons, especially the ease with which morphological data can be had from preserved museum specimens, are manifold. But considered objectively (outside its context of "tradition"), morphological analysis alone is a poor tool for probing evolutionary processes or elucidating relationships. The concepts of "relationship" and of "evolution" are inherently genetic ones, and the genetic bases of morphological traits are seldom known in detail and frequently unknown entirely. Earlier in this century, several workers, notably Gordon, Kosswig, Schmidt, and, in his salad years, Carl Hubbs, pioneered the application of genetic techniques and modes of reasoning to ichthyology. While certain that most contemporary ichth yologists are familiar with this body of work, I am almost equally certain that few of them regard it as pertinent to their own efforts.



Experiments In Hearing


Experiments In Hearing
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Author : Georg Von Békésy
language : en
Publisher: Acoustical Society of Amer
Release Date : 1960

Experiments In Hearing written by Georg Von Békésy and has been published by Acoustical Society of Amer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1960 with Health & Fitness categories.




Cochlear Mechanics


Cochlear Mechanics
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Author : Frank Böhnke
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 1999

Cochlear Mechanics written by Frank Böhnke and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Cochlea categories.


This special issue collects our current knowledge of the mechanical processing of acoustic signals by the cochlea and its containing structures. Many workers in diverse disciplines in otology use the facts from cochlear mechanics for the interpretation of their results. Presented here for the first time is the development of a three-dimensional mechanical model of the curved cochlea including fluid-structure couplings. An important approach for future cochlear modeling is shown by the provision of geometrical data for the input of three-dimensional finite element models by microtomographic imaging. A remarkable article tries to demonstrate a connection between outer hair cell mechanics and the complex phenomenon of tinnitus and will be of special interest for stress engineers. Owing to its strong interdisciplinarity, this issue is not only intended for biophysicists, ENT clinicians and audiologists but also for radiologists, biomechanical engineers and computer engineers.



Auditory Information Processing


Auditory Information Processing
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Author : Harunori Ohmori
language : en
Publisher: Springer Nature
Release Date : 2019-11-26

Auditory Information Processing written by Harunori Ohmori and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-26 with Medical categories.


This book explains neural function at the level of ion channels and membrane excitability in neurons along the ascending auditory pathway. Airborne sound information is captured by the ears, transformed to neural electrical signals, and then processed in the brain. Readers will find full descriptions of these processes of signal transduction and transformation. First, it is described how, at the level of hair cells, the receptor cells in the cochlea, the sound-evoked vibration is transduced to electrical signals and transmitted to the auditory nerve fibers. In the second section it is explained how the electrical activity of these fibers is processed at the cochlear nucleus in order to extract the temporal and level information of sound separately and then transmitted to the third nucleus for processing of the interaural differences, such as the interaural time difference and the interaural level difference. The third section summarizes the transformation of auditory temporal information to the rate of neural firing activity in the midbrain and the higher nuclei, including the cortex, based on in vivo results. Finally, emerging new technologies to investigate auditory signal processing are reviewed and discussed.



Hearing Loss Mechanisms Prevention And Cure


Hearing Loss Mechanisms Prevention And Cure
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Author : Huawei Li
language : en
Publisher: Springer
Release Date : 2019-03-26

Hearing Loss Mechanisms Prevention And Cure written by Huawei Li and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-26 with Medical categories.


This book systematically discusses the pathogenesis, prevention, and the current and potential clinical treatment of hearing loss, as well as the latest advances in hearing research. Hearing loss is a prevalent sensory disorder, which according to a 2015 World Health Organization (WHO) report affected 9% of the global population in 2015. As populations continue to age, more and more people are suffering from the condition, with 60% of those aged between 65 and 75 affected. Hearing loss seriously affects patients’ ability to work ability and quality of life, and as such deafness has become an increasingly urgent social problem around the globe. Sensorineural hearing loss is mainly caused by damage to the hair cells (HCs), and the subsequent loss of spiral ganglion neurons (SGNs). Damage to the HCs in the inner ear can result from exposure to loud noises and environmental and chemical toxins as well as genetic disorders, aging, and certain medications. This book provides ENT specialists and researchers, as well as individuals affected a comprehensive introduction to the field of hearing loss.



Store Operated Calcium Channels


Store Operated Calcium Channels
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Author :
language : en
Publisher: Academic Press
Release Date : 2013-07-24

Store Operated Calcium Channels written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-24 with Science categories.


Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels. Contributors are authoritative researchers who have produced important advances in the field. The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject.