Cell And Tissue Culture Models In Dermatological Research
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Cell And Tissue Culture Models In Dermatological Research
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Author : August Bernd
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Cell And Tissue Culture Models In Dermatological Research written by August Bernd and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In this volume the impact of cell culture models on dermatological research is discussed by scientists from medicine, physiology, biology, pharmacology,and pharmacy. The book includes the following topics: orthology and pathology of the skin, differentiation of keratinocytes and fibroblasts, problems of the cultivation of melanocytes, biochemistry of pigment metabolism, models for wound healing and tissue renewal, fibroblast function and metabolism of collagen, models for the investigation of ageing as well as models for pharmacological and toxicologial tests. Thus, a wide arch is spanned, from basic problems with cultivation and characterization of cell cultures to examples of application. Dermatologists as well as cell biologists will benefit from this publication.
Skin Tissue Models
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Author : Alexandra P. Marques
language : en
Publisher: Academic Press
Release Date : 2017-11-14
Skin Tissue Models written by Alexandra P. Marques and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-14 with Science categories.
Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury – from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as study platforms of skin biology and emerging technologies. The editors have created a table of contents which frames the relevance of skin tissue models for researchers as platforms to study skin biology and therapeutic approaches for different skin diseases, for clinicians as tissue substitutes, and for cosmetic and pharmaceutical industries as alternative test substrates that can replace animal models. Offers descriptions of the normal structure/function of mammalian skin, exposure to clinical problems, and more Presents coverage of skin diseases (cancer, genodermatoses, vitiligo and psoriasis) that extends to clinical requirements and skin diseases in vitro models Addresses legal requirements and ethical concerns in drugs and cosmetics in vitro testing Edited and authored by internationally renowned group of researchers, presenting the broadest coverage possible
3d Cell Culture
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Author : John Haycock
language : en
Publisher: Humana Press
Release Date : 2010-11-02
3d Cell Culture written by John Haycock and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-02 with Science categories.
Developed for a range of tissues where the culture environment takes into account the spatial organization of the cells therein, 3D cell culture models serve to bridge the gap between in vivo studies at one extreme with that of simple cell monolayers at the other. In 3D Cell Culture: Methods and Protocols, international experts describe a number of basic and applied methodologies taken from a breadth of scientific and engineering disciplines, many of which deal with direct applications of 3D culture models, most notably in the formation of tissues for clinical purpose. Beginning with an overview of the biological and materials scaffold requirements for successfully creating 3D models, the book delves into topics such as general scaffold design and fabrication techniques, models for bone, skin, cartilage, nerve, bladder, and hair follicles, and chapters on bioreactor design, imaging, and stem cells. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include brief introductions to their respective subjects, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, 3D Cell Culture: Methods and Protocols serves as a basic manual for laboratory-based scientists who not only need to have a comprehensive range of techniques contained within a single text but also require techniques described using a standard, convenient format.
Dermatopharmacology Of Topical Preparations
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Author : B. Gabard
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-28
Dermatopharmacology Of Topical Preparations written by B. Gabard and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-28 with Medical categories.
Proof of the efficacy of dermatological products is a prerequisite for clinical testing and registration. Now, efficacy claims for cosmetics must be equally substantiated. This book provides a concise, practical but comprehensive overview of experimental models used to screen, develop and select dermatological and cosmetic formulations. The authors are recognized specialists in their field and use a standardized approach to the projects facilitating the reading for the stressed scientist, for the R+D managers general view as well as for the beginners in the field.
Molecular Dermatology
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Author : Natalia V. Botchkareva
language : en
Publisher: Humana
Release Date : 2020-04-21
Molecular Dermatology written by Natalia V. Botchkareva and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-21 with Science categories.
This volume delivers the most important laboratory techniques that underlie dermatological investigation, including in situ, in vitro, ex vivo, and in vivo models of skin, its appendages (hair follicles, sebaceous and sweat glands), and immune cells. Also included are unique techniques that unravel epigenetic mechanisms in skin and hair follicle cells, such as gene organization in the nucleus and gene expression regulation by the non-coding transcriptome, which are important recent developments in investigative dermatology. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Molecular Dermatology: Methods and Protocols serves as an essential resource for researchers working in the areas of fundamental as well as applied dermatological science.
Three Dimensional Human Organotypic Models For Biomedical Research
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Author : Fabio Bagnoli
language : en
Publisher: Springer Nature
Release Date : 2021-05-20
Three Dimensional Human Organotypic Models For Biomedical Research written by Fabio Bagnoli and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-20 with Medical categories.
This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.
National Library Of Medicine Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1993
National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medicine categories.
Alternatives To Animal Testing
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Author : Hajime Kojima
language : en
Publisher: Springer
Release Date : 2018-12-27
Alternatives To Animal Testing written by Hajime Kojima and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-27 with Medical categories.
This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.
Late Sequelae In Oncology
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Author : Jürgen Dunst
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Late Sequelae In Oncology written by Jürgen Dunst and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Increasing survival figures and the use of more intense combined treatment regimens in modern oncology have raised the problem of late therapeutic sequelae in long-term survivors after cancer. Recent scientific approaches to late sequelae concentrate on the evaluation of subclinical changes with sophisticated functional measurements and experimental investigation of the underlying pathophysiological mechanisms. The objective of the book is to bring together these recent clinical and experimental data from different medical disciplines to give an overview of the most relevant problems of late sequelae. In clinical practice the book may help regarding estimation of risks, selection of diagnostic methods, and estimation of the prognosis of late sequelae.
Ultrasonic Nondestructive Evaluation
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Author : Tribikram Kundu
language : en
Publisher: CRC Press
Release Date : 2003-12-29
Ultrasonic Nondestructive Evaluation written by Tribikram Kundu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-29 with Science categories.
Most books on ultrasonic nondestructive evaluation (NDE) focus either on its theoretical background or on advanced applications. Furthermore, information on the most current applications, such as guided wave techniques and acoustic microscopy, is scattered throughout various conference proceedings and journals. No one book has integrated these aspe