Skin Tissue Models
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Skin Tissue Models
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Author : Alexandra P. Marques
language : en
Publisher: Academic Press
Release Date : 2017-11-14
Skin Tissue Models written by Alexandra P. Marques and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-14 with Science categories.
Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury – from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as study platforms of skin biology and emerging technologies. The editors have created a table of contents which frames the relevance of skin tissue models for researchers as platforms to study skin biology and therapeutic approaches for different skin diseases, for clinicians as tissue substitutes, and for cosmetic and pharmaceutical industries as alternative test substrates that can replace animal models. Offers descriptions of the normal structure/function of mammalian skin, exposure to clinical problems, and more Presents coverage of skin diseases (cancer, genodermatoses, vitiligo and psoriasis) that extends to clinical requirements and skin diseases in vitro models Addresses legal requirements and ethical concerns in drugs and cosmetics in vitro testing Edited and authored by internationally renowned group of researchers, presenting the broadest coverage possible
Skin Tissue Engineering
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Author : Sophie Böttcher-Haberzeth
language : en
Publisher: Springer Nature
Release Date : 2019-05-30
Skin Tissue Engineering written by Sophie Böttcher-Haberzeth and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-30 with Science categories.
This volume provides protocols describing the isolation and culture of diverse cell types stemming from the skin and the use of these cells and cell constructs for wound healing, bioengineering applications, and translational medicine purposes. The book is divided into three sections describing the isolation and culture of diverse skin cells, managing these cells within co-culture systems and skin models, as well as using these skin models in a test setting. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Skin Tissue Engineering: Methods and Protocols serves as a vital aid to basic and clinical researchers such as biologists, physicians, and biomedical engineers working with and being interested in basic science, and clinically and laboratory-applicable translational regenerative medicine.
Skin Tissue Engineering And Regenerative Medicine
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Author : Mohammad Albanna
language : en
Publisher: Academic Press
Release Date : 2016-01-14
Skin Tissue Engineering And Regenerative Medicine written by Mohammad Albanna and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-14 with Technology & Engineering categories.
The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios. Explores cellular and molecular processes of wound healing, scar formation, and dermal repair Includes examples of animal models for wound healing and translation to the clinical world Presents the current state of, and clinical opportunities for, extracellular matrices, natural biomaterials, synthetic biomaterials, biologic skin substitutes, and adult and fetal stem and skin cells for skin regenerative therapies and wound management Discusses new innovative approaches for wound healing including skin bioprinting and directed cellular therapies
Skin Models
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Author : Ronald Marks
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Skin Models written by Ronald Marks and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In the last fifty years dramatic progress has been made in the under standing of skin and skin diseases. Although we are still someway off understanding the ultimate causes of such disorders as psoriasis, atopic dermatitis and the congenital disorder of keratinization, we now have considerable information on the physiological disturbances in various diseases. This has permitted and encouraged a rational approach to treatment. The successful use of antimitotic agents, immunomodulators and retinoids may be cited as examples. A major reason for this im provement may be the fact that researchers accept models for the in vestigation of skin diseases. Increasing numbers of them have become available in the past years. So many have been described that it is doubtful whether anyone researcher is aware of all the other models described - even in his own field of interest. This book is a challenge for those involved in the study of skin and its disorders to use the sundry models of skin that have proven helpful. It would be impossible for this work to be all-embracing but it is hoped that the choice of models offered in this publication will be stimulating and helpful in the solution of knotty skin questions. April,1986 Ronald Marks, Cardiff Gerd Plewig, DUsseldorf Table of Contents In Vivo Models Human Model for Acne . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 L. C Brummitt, W. J. Cunliffe, G. Gowland Models to Study Follicular Diseases l3 G. Plewig Models for Wound Healing. . . . . . . . . . . . . . . . . . . . . . . . . 24 R. Marks, D. Williams, A. D.
Function Oriented Bioengineered Skin Equivalents
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Author : Tanja Zidarič
language : en
Publisher: Springer Nature
Release Date : 2023-01-01
Function Oriented Bioengineered Skin Equivalents written by Tanja Zidarič and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-01 with Technology & Engineering categories.
The book Function-oriented bioengineered skin equivalents - continuous development towards complete skin replication aims to provide potential readers with a comprehensive summary of the available information on various in vitro skin models, from historical background to different modeling approaches and their applications. Particular emphasis is placed on presenting the current technological components available for the development of engineered skin equivalents by summarizing advances in cell cultivation, materials science, and bioengineering. Using examples of the current-state-of-art, we describe the advantages, limitations, and challenges of developing in vitro skin models for successful use in clinical applications and skin-related research.
Dynamic Skin On A Chip Models
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Author : Katharina Kaiser
language : en
Publisher:
Release Date : 2023
Dynamic Skin On A Chip Models written by Katharina Kaiser and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with categories.
Biomaterials For Skin Repair And Regeneration
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Author : Elena Garcia-Gareta
language : en
Publisher: Woodhead Publishing
Release Date : 2019-06-05
Biomaterials For Skin Repair And Regeneration written by Elena Garcia-Gareta and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-05 with Medical categories.
Biomaterials for Skin Repair and Regeneration examines a range of materials and technologies used for regenerating or repairing skin. With a strong focus on biomaterials and scaffolds, the book also examines the testing and evaluation pathway for human clinical trials. Beginning by introducing the fundamentals on skin tissue, the book goes on to describe contemporary technology used in skin repair as well as currently available biomaterials suitable for skin tissue repair and regeneration. Skin tissue engineering and the ideal requirements to take into account when developing skin biomaterials are discussed, followed by information on the individual materials used for skin repair and regeneration. As evaluation of biomaterials in animal models is mandatory before proceeding into human clinical trials, the book also examines the different animal models available. With a strong focus on materials, engineering, and application, this book is a valuable resource for materials scientists, skin biologists, and bioengineers with an interest in tissue engineering, regeneration, and repair of skin. Provides an understanding of basic skin biology Comprehensively examines a variety of biomaterial approaches Looks at animal models for the evaluation of biomaterial-based skin constructs
Cell And Tissue Culture Models In Dermatological Research
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Author : August Bernd
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Cell And Tissue Culture Models In Dermatological Research written by August Bernd and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In this volume the impact of cell culture models on dermatological research is discussed by scientists from medicine, physiology, biology, pharmacology,and pharmacy. The book includes the following topics: orthology and pathology of the skin, differentiation of keratinocytes and fibroblasts, problems of the cultivation of melanocytes, biochemistry of pigment metabolism, models for wound healing and tissue renewal, fibroblast function and metabolism of collagen, models for the investigation of ageing as well as models for pharmacological and toxicologial tests. Thus, a wide arch is spanned, from basic problems with cultivation and characterization of cell cultures to examples of application. Dermatologists as well as cell biologists will benefit from this publication.
Biofabrication And 3d Tissue Modeling
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Author : Dong-Woo Cho
language : en
Publisher: Royal Society of Chemistry
Release Date : 2019-01-02
Biofabrication And 3d Tissue Modeling written by Dong-Woo Cho and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-02 with Technology & Engineering categories.
3D tissue modelling is an emerging field used for the investigation of disease mechanisms and drug development. The two key drivers of this upsurge in research lie in its potential to offer a way to reduce animal testing with respect to biotoxicity analysis, preferably on physiology recapitulated human tissues and, additionally, it provides an alternative approach to regenerative medicine. Integrating physics, chemistry, materials science, and stem cell and biomedical engineering, this book provides a complete foundation to this exciting, and interdisciplinary field. Beginning with the basic principles of 3D tissue modelling, the reader will find expert reviews on key fabrication technologies and processes, including microfluidics, microfabrication technology such as 3D bioprinting, and programming approaches to emulating human tissue complexity. The next stage introduces the reader to a range of materials used for 3D tissue modelling, from synthetic to natural materials, as well as the emerging field of tissue derived decellularized extracellular matrix (dECM). A whole host of critical applications are covered, with several chapters dedicated to hard and soft tissues, as well as focused reviews on the respiratory and central nervous system. Finally, the development of in vitro tissue models to screen drugs and study progression and etiologies of diseases, with particular attention paid to cancer, can be found.
Skin 3 D Models And Cosmetics Toxicity
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Author : Aditya Bhushan Pant
language : en
Publisher: Springer Nature
Release Date : 2023-08-28
Skin 3 D Models And Cosmetics Toxicity written by Aditya Bhushan Pant and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-28 with Medical categories.
Efforts are being made by research organizations and cosmetic industries worldwide to develop more precise and targeted 3D models that mimic humans for testing cosmetic and personal health care product ingredients, following a complete ban on animal testing. This book includes several subtopics dedicated to the progress made, challenges faced, roadblocks encountered, and future prospects in the development and validation of 3D models for testing these products. The book consist of an editorial and 14 themed chapters that will showcase the significant progress made so far, challenges encountered, and future prospects in the development of 3D reconstruct models.