Cell And Tissue Reaction Engineering
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Cell And Tissue Reaction Engineering
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Author : Regine Eibl
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-09-30
Cell And Tissue Reaction Engineering written by Regine Eibl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-30 with Science categories.
The completion of the Human Genome Project and the rapid progress in cell bi- ogy and biochemical engineering, are major forces driving the steady increase of approved biotech products, especially biopharmaceuticals, in the market. Today mammalian cell products (“products from cells”), primarily monoclonals, cytokines, recombinant glycoproteins, and, increasingly, vaccines, dominate the biopharmaceutical industry. Moreover, a small number of products consisting of in vitro cultivated cells (“cells as product”) for regenerative medicine have also been introduced in the market. Their efficient production requires comprehensive knowledge of biological as well as biochemical mammalian cell culture fundamentals (e.g., cell characteristics and metabolism, cell line establishment, culture medium optimization) and related engineering principles (e.g., bioreactor design, process scale-up and optimization). In addition, new developments focusing on cell line development, animal-free c- ture media, disposables and the implications of changing processes (multi-purpo- facilities) have to be taken into account. While a number of excellent books treating the basic methods and applications of mammalian cell culture technology have been published, only little attention has been afforded to their engineering aspects. The aim of this book is to make a contribution to closing this gap; it particularly focuses on the interactions between biological and biochemical and engineering principles in processes derived from cell cultures. It is not intended to give a c- prehensive overview of the literature. This has been done extensively elsewhere.
Cell And Tissue Reaction Engineering
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Author : Regine Eibl
language : en
Publisher: Springer
Release Date : 2009-08-29
Cell And Tissue Reaction Engineering written by Regine Eibl and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-29 with Science categories.
The completion of the Human Genome Project and the rapid progress in cell bi- ogy and biochemical engineering, are major forces driving the steady increase of approved biotech products, especially biopharmaceuticals, in the market. Today mammalian cell products (“products from cells”), primarily monoclonals, cytokines, recombinant glycoproteins, and, increasingly, vaccines, dominate the biopharmaceutical industry. Moreover, a small number of products consisting of in vitro cultivated cells (“cells as product”) for regenerative medicine have also been introduced in the market. Their efficient production requires comprehensive knowledge of biological as well as biochemical mammalian cell culture fundamentals (e.g., cell characteristics and metabolism, cell line establishment, culture medium optimization) and related engineering principles (e.g., bioreactor design, process scale-up and optimization). In addition, new developments focusing on cell line development, animal-free c- ture media, disposables and the implications of changing processes (multi-purpo- facilities) have to be taken into account. While a number of excellent books treating the basic methods and applications of mammalian cell culture technology have been published, only little attention has been afforded to their engineering aspects. The aim of this book is to make a contribution to closing this gap; it particularly focuses on the interactions between biological and biochemical and engineering principles in processes derived from cell cultures. It is not intended to give a c- prehensive overview of the literature. This has been done extensively elsewhere.
Standardisation In Cell And Tissue Engineering
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Author : V Salih
language : en
Publisher: Elsevier
Release Date : 2013-07-31
Standardisation In Cell And Tissue Engineering written by V Salih and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-31 with Science categories.
The increased use of biodegradable synthetic or natural scaffolds combined with cells and/or biological molecules, in order to create functional replacement tissue in a damaged tissue site, has led to the need for the development of ‘best practice’ methods in the area of tissue engineering to help ensure the creation of safe, high quality products. Standardisation in cell and tissue engineering introduces concepts and current practice in the field of cell and tissue engineering to a wide audience and aims to provide awareness of the importance of standardisation in this area while suggesting directions for further investigation. Part one provides an overview of methods for cell and tissue engineering and includes chapters on the fundamentals of cell and matrix biology for tissue engineering, 3D collagen biomatrix development, and control and vascularisation of tissue-engineered constructs. Part two begins with a chapter exploring the methods and protocols of standardisation in cell and tissue engineering before moving on to highlight issues of quality control in cell and tissue engineering, standardised chemical analysis and testing of biomaterials and principles of good laboratory practice (GLP) for in vitro cell culture applications. Standardisation in cell and tissue engineering is a standard reference for leading research groups, government agencies, regulatory bodies, and researchers and technicians at all levels across the whole range of disciplines using cell culture within the pharmaceutical, biotechnology and biomedical industries. Introduces concepts and current practice in the field of cell and tissue engineering Highlights the importance of standardisation in cell and tissue engineering and suggests directions for further investigation Explores methods and protocols of standardisation in cell and tissue engineering and issues of quality control in cell and tissue engineering
Tissue Engineering Ii
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Author : Kyongbum Lee
language : en
Publisher: Springer
Release Date : 2006-10-19
Tissue Engineering Ii written by Kyongbum Lee and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-19 with Technology & Engineering categories.
It is our pleasure to present this special volume on tissue engineering in the series Advances in Biochemical Engineering and Biotechnology. Thisvolume re?ects the emergence of tissue engineering as a core discipline of modern biomedical engineering, and recognizes the growing synergies between the technological developments in biotechnology and biomedicine. Along this vein, the focusof thisvolume istoprovide abiotechnology driven perspective on cell engineering fundamentals while highlighting their signi?cance in p- ducing functional tissues. Our aim is to present an overview of the state of the art of a selection of these technologies, punctuated with current applications in the research and development of cell-based therapies for human disease. To prepare this volume, we have solicited contributions from leaders and experts in their respective ?elds, ranging from biomaterials and bioreactors to gene delivery and metabolic engineering. Particular emphasis was placed on including reviews that discuss various aspects of the biochemical p- cesses underlying cell function, such as signaling, growth, differentiation, and communication. The reviews of research topics cover two main areas: cel- lar and non-cellular components and assembly; evaluation and optimization of tissue function; and integrated reactor or implant system development for research and clinical applications. Many of the reviews illustrate how bioche- cal engineering methods are used to produce and characterize novel materials (e. g. genetically engineered natural polymers, synthetic scaffolds with ce- type speci?c attachment sites or inductive factors), whose unique properties enable increased levels of control over tissue development and architecture.
Bioreactors For Tissue Engineering
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Author : Julian Chaudhuri
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-01-16
Bioreactors For Tissue Engineering written by Julian Chaudhuri and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-16 with Medical categories.
For the first time in a single volume, the design, characterisation and operation of the bioreactor system in which the tissue is grown is detailed. Bioreactors for Tissue Engineering presents an overall picture of the current state of knowledge in the engineering of bioreactors for several tissue types (bone, cartilage, vascular), addresses the issue of mechanical conditioning of the tissue, and describes the use of techniques such as MRI for monitoring tissue growth. This unique volume is dedicated to the fundamentals and application of bioreactor technology to tissue engineering products. Not only will it appeal to graduate students and experienced researchers in tissue engineering and regenerative medicine, but also to tissue engineers and culture technologists, academic and industrial chemical engineers, biochemical engineers and cell biologists who wish to understand the criteria used to design and develop novel systems for tissue growth in vitro.
Reaction Engineering
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Author : H. Binder
language : en
Publisher: Springer
Release Date : 2013-11-20
Reaction Engineering written by H. Binder and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-20 with Science categories.
With contributions by numerous experts
Transport Phenomena In Biomedical Engineering
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Author : Robert A. Peattie
language : en
Publisher: CRC Press
Release Date : 2012-11-20
Transport Phenomena In Biomedical Engineering written by Robert A. Peattie and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-20 with Medical categories.
Design, analysis and simulation of tissue constructs is an integral part of the ever-evolving field of biomedical engineering. The study of reaction kinetics, particularly when coupled with complex physical phenomena such as the transport of heat, mass and momentum, is required to determine or predict performance of biologically-based systems whether for research or clinical implementation. Transport Phenomena in Biomedical Engineering: Principles and Practices explores the concepts of transport phenomena alongside chemical reaction kinetics and thermodynamics to introduce the field of reaction engineering as it applies to physiologic systems in health and disease. It emphasizes the role played by these fundamental physical processes. The book first examines elementary concepts such as control volume selection and flow systems. It provides a comprehensive treatment with an overview of major research topics related to transport phenomena pertaining to biomedical engineering. Although each chapter is self-contained, they all bring forth and reinforce similar concepts through applications and discussions. With contributions from world-class experts, the book unmasks the fundamental phenomenological events in engineering devices and explores how to use them to meet the objectives of specific applications. It includes coverage of applications to drug delivery and cell- and tissue-based therapies.
Principles Of Tissue Engineering
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Author : Robert Lanza
language : en
Publisher: Academic Press
Release Date : 2011-10-13
Principles Of Tissue Engineering written by Robert Lanza and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-13 with Science categories.
First published in 1997, Principles of Tissue Engineering is the widely recognized definitive resource in the field. The third edition provides a much needed update of the rapid progress that has been achieved in the field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. This edition includes greatly expanded focus on stem cells, including adult and embryonic stem cells and progenitor populations that may soon lead to new tissue engineering therapies for heart disease, diabetes, and a wide variety of other diseases that afflict humanity. This up-to-date coverage of stem cell biology and other emerging technologies is complemented by a series of new chapters on recent clinical experience in applying tissue engineering. The result is a comprehensive textbook that we believe will be useful to students and experts alike. New to this edition:*Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves*Expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems
Bioengineering In Cell And Tissue Research
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Author : Gerhard M. Artmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-04-09
Bioengineering In Cell And Tissue Research written by Gerhard M. Artmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-09 with Technology & Engineering categories.
Cutting edge research in cell and tissue research abounds in this review of the latest technological developments in the area. The chapters are written by excellent scientists on advanced, frontier technology and address scientific questions that require considerable engineering brainpower. The aim is to provide students and scientists working in academia and industry new information on bioengineering in cell and tissue research to enhance their understanding and innovation.
Tissue Engineering
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Author : Hansjörg Hauser
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-07-27
Tissue Engineering written by Hansjörg Hauser and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-27 with Medical categories.
Features: Leading experts present their own most recent advances, Includes a wide spectrum of methods representing tissue engineering in many diverse disciplines, Supplies an understanding of diverse technologies and methods.