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Cell Cycle Materials And Methods


Cell Cycle Materials And Methods
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Cell Cycle Materials And Methods


Cell Cycle Materials And Methods
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Author : Michele Pagano
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Cell Cycle Materials And Methods written by Michele Pagano and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


During their lifetime, especially when growing and dividing, cells go through various steps of the cell cycle. Knowledge of the individual steps of the cell cycle will help us understand the development of a variety of diseases better, including cancer, and also to design new drugs against it. New techniques for studying the molecular basis of these processes have recently been developed and are described in detail in this manual. A glossary helps the reader to cope with the complex cell cycle terminology.



Techniques In Cell Cycle Analysis


Techniques In Cell Cycle Analysis
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Author : Joe W. Gray
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-24

Techniques In Cell Cycle Analysis written by Joe W. Gray and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-24 with Science categories.


Quantification of the proliferative characteristics of normal and malignant cells has been of interest to oncolo gists and cancer biologists for almost three decades. This interest stems from (a) the fact that cancer is a disease of uncontrolled proliferation, (b) the finding that many of the commonly used anticancer agents are preferentially toxic to cells that are actively proliferating, and (c) the observa tion that significant differences in proliferation characteristics exist between normal and malignant cells. Initially, cell cycle analysis was pursued enthusiastically in the hope of gener ating information useful for the development of rational cancer therapy strategies; for example, by allowing identi fication of rapidly proliferating tumors against which cell cycle-specific agents could be used with maximum effec tiveness and by allowing rational scheduling of cell cyc- specific therapeutic agents to maximize the therapeutic ratio. Unfortunately, several difficulties have prevented realiza tion of the early promise of cell cycle analysis: Proliferative patterns of the normal and malignant tissues have been found to be substantially more complex than originally an ticipated, and synchronization of human tumors has proved remarkably difficult. Human tumors of the same type have proved highly variable, and the cytokinetic tools available for cell cycle analysis have been labor intensive, as well as somewhat subjective and in many cases inapplicable to humans. However, the potential for substantially improved cancer therapy remains if more accurate cytokinetic infor mation about human malignancies and normal tissues can be obtained in a timely fashion.



Journal


Journal
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Author : National Cancer Institute (U.S.)
language : en
Publisher:
Release Date : 1974

Journal written by National Cancer Institute (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1974 with Cancer categories.




Bacterial Transcription Factors And The Cell Cycle


Bacterial Transcription Factors And The Cell Cycle
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Author : Morigen Morigen
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-10

Bacterial Transcription Factors And The Cell Cycle written by Morigen Morigen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-10 with Science categories.




Cell Cycle Control


Cell Cycle Control
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Author : Anna Castro
language : en
Publisher: Springer Nature
Release Date : 2024-02-23

Cell Cycle Control written by Anna Castro and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-23 with Science categories.


This detailed volume collects techniques to study the highly regulated cell cycle process. Beginning with chapters investigating these processes and assessing how cells respond when these complicated pathways are simplified by using synthetic biology and in vitro reconstitutions, the book continues by exploring how cells sense and respond to environmental conditions, different model systems and cellular types used to visualize cellular architecture during cell division, as well as innovative single cell microscopy techniques to highlight the heterogeneity of the cell population with respect to cell cycle progression. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cell Cycle Control: Methods and Protocols serves as an ideal guide for researchers attempting to elucidate this vital area of cell biology.



Journal Of The National Cancer Institute


Journal Of The National Cancer Institute
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Author : National Cancer Institute (U.S.)
language : en
Publisher:
Release Date : 1978

Journal Of The National Cancer Institute written by National Cancer Institute (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Cancer categories.




Journal Of The National Cancer Institute


Journal Of The National Cancer Institute
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Author :
language : en
Publisher:
Release Date : 1983

Journal Of The National Cancer Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Cancer categories.




Animal Cell Culture Techniques


Animal Cell Culture Techniques
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Author : Martin Clynes
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Animal Cell Culture Techniques written by Martin Clynes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Cell culture techniques allow a variety of molecular and cell biological questions to be addressed, offering physiological conditions whilst avoiding the use of laboratory animals. In addition to basic techniques, a wide range of specialised practical protocols covering the following areas are included: cell proliferation and death, in-vitro models for cell differentiation, in-vitro models for toxicology and pharmacology, industrial application of animal cell culture, genetic manipulation and analysis of human and animal cells in culture.



Cell Imaging Techniques


Cell Imaging Techniques
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Author : Douglas J. Taatjes
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-04

Cell Imaging Techniques written by Douglas J. Taatjes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-04 with Science categories.


A diverse collection of state-of-the-art methods for the microscopic imaging of cells and molecules. The authors cover a wide spectrum of complimentary techniques, including such methods as fluorescence microscopy, electron microscopy, atomic force microscopy, and laser scanning cytometry. Additional readily reproducible protocols on confocal scanning laser microscopy, quantitative computer-assisted image analysis, laser-capture microdissection, microarray image scanning, near-field scanning optical microscopy, and reflection contrast microscopy round out this eclectic collection of cutting-edge imaging techniques now available. The authors also discuss preparative methods for particles and cells by transmission electron microscopy.



Regulation Of Prokaryotic Cell Division


Regulation Of Prokaryotic Cell Division
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Author : Joe Lutkenhaus
language : en
Publisher: Frontiers Media SA
Release Date : 2023-02-16

Regulation Of Prokaryotic Cell Division written by Joe Lutkenhaus and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-16 with Medical categories.