Cell Interactions In Atherosclerosis


Cell Interactions In Atherosclerosis
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Cell Interactions In Atherosclerosis


Cell Interactions In Atherosclerosis
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Author : Horst Robenek
language : en
Publisher: CRC Press
Release Date : 1992-09-25

Cell Interactions In Atherosclerosis written by Horst Robenek and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-09-25 with Medical categories.


Cell Interactions in Atherosclerosis covers the scientific foundations of the most important disease inflicting the developed world today. It presents a collection of topical aspects on the general theme of cell interactions in atherosclerosis, providing authoritative, up-to-the-minute accounts of how new developments in cell biology have advanced our understanding of these cellular interactions. The book is amply illustrated with electron micrographs and light micrographs incorporating modern cytochemical procedures. Cell Interactions in Atherosclerosis will interest all medical and scientific professionals dealing with atherosclerosis and heart disease.



Atherosclerosis


Atherosclerosis
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Author : Sergey Fedoroff
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Atherosclerosis written by Sergey Fedoroff and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


This volume contains the papers which were presented at the First Altschul Symposium, Atherosclerosis: Cellular and Molecular Interactions in the Artery Wall. The symposium was held in Saskatoon, at the University of Saskatchewan in May 1990 in memory of Dr. Rudolph Altschul, a pioneer in the field of vascular biology and the prevention of atherosclerosis. Dr. Altschul was Professor and Head of the Department of Anatomy at the University of Saskatchewan from 1955 to 1963. The challenge for biomedical scientists is to unravel the multifactorial etiology of atherosclerosis. For the last hundred and sixty years, anatomical pathologists have carefully studied the morphological changes of the human vascular wall during the initiation and evolution of the fibrofatty atherosclerotic plaque. Based on these elegant morphological observations, theories on atherogenesis were put forth by pathologists in the 1840's. Rudolf Virchow suggested that the movement of substances from the blood into the vessel wall was important for atherogenesis while Carl von Rokitansky felt that the deposition of substances on the lumenal surface of the artery resulted in the formation of atherosclerotic plaque. Since these original theories, it has become apparent that the pathogenesis of atherosclerosis is multifactorial and the disease evolves in stages. It is also likely that not all plaques arise through the same sequence of events and that many steps are involved in the development of each plaque. Today, our understanding of the complicated processes of atherogenesis is still incomplete.



Atherosclerosis


Atherosclerosis
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Author : R. T. Dean
language : en
Publisher: Oxford University Press, USA
Release Date : 2000

Atherosclerosis written by R. T. Dean and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.


This book provides a critical review of the oxidative theory of atherosclerosis as well as highlighting new trends in research from basic to clinical, academic to commercial. The contributions of diabetes, vascular dysfunction, blood coagulation, plaque rupture, oxidative stress, lymphocytes, macrophages, growth factors, cytokines, and oxysterols to atherogenesis are all discussed, as are the roles of smooth muscle and endothelial cells. A summary of the current methods of diagnosis and the future prospect of using biochemical markers from plasma is also discussed. There is a critical look at gene therapy and other future therapeutic strategies based on the molecular and cellular causes of atherosclerosis. Each chapter is written by two or more authors from different laboratories to ensure a balanced approach. It will be invaluable to all biochemical researchers with a specialist or passing interest in atherosclerosis research. presents a critical look



Atherosclerosis


Atherosclerosis
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Author : Peter C. Weber
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1993

Atherosclerosis written by Peter C. Weber and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.




Atherosclerosis


Atherosclerosis
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Author : Peter C. Weber
language : en
Publisher:
Release Date : 1993

Atherosclerosis written by Peter C. Weber and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with categories.




Molecular Biology Of The Arterial Wall


Molecular Biology Of The Arterial Wall
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Author : Gotthard Schettler
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Molecular Biology Of The Arterial Wall written by Gotthard Schettler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


The outstanding contributions to this volume are designed to shed light on some fields of cell biology and cellular pathology, including newly observed phenomena of cell-cell interactions, which might be applicable in studying the pathological process of atherosclerosis. The topics included cover: lipoproteins and lipoprotein receptors; growth factors; endocytosis and exocytosis; ONC Genes and proliferative disease; white blood cells; prostaglandins and leukotrienes; and the biology of smooth muscle and endothelium. The volume provides a complete summary of the most important developments in the field with great impact for arteriosclerosis research.



Effects Of Cell Interactions At The Endothelium In Leukocyte Differentiation And Polarization During Inflammation


Effects Of Cell Interactions At The Endothelium In Leukocyte Differentiation And Polarization During Inflammation
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Author : Alain Haziot
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-27

Effects Of Cell Interactions At The Endothelium In Leukocyte Differentiation And Polarization During Inflammation written by Alain Haziot and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-27 with Medical categories.


A complex exchange of signals between endothelial cells and tissues occurs during steady-state and in inflammatory conditions. These interactions involve numerous cell types including an active contribution from endothelial cells and occur on both sides of the endothelial monolayer. In addition to functioning as selective permeability barriers, it is increasingly recognized that local cell attraction to endothelial cells provides the potential for focal interactions between relevant cells. In this context, cellular interactions taking place at the surface of the endothelium and within the perivascular spaces are thought to initiate crucial steps in the generation and shaping of immune responses. Blood elements (such as leukocytes, platelets, and vesicles) converge to the barrier formed by the endothelium where perivascular (such as macrophages, pericytes) initiate, convey, and/or amplify signals revealing tissue status. The innate and adaptative functions of endothelial cells themselves together with the immune functions of assembled cells at a focal point in capillaries create the potential for exchange of signals and dynamic fine tuning of responses through cell programming and cell selection. The resulting immune response may range from inadequate immunity and/or exhaustion to excess tissue destruction and fibrosis. Productive inflammation and its resolution are critically reliant on which cells are recruited and in which order, their state of activation, and interactions between recruited cells. Tissue-dependent signals further shape the recruitment of leukocytes to the endothelium. In the kidney for instance, in the presence of immune complexes, perivascular resident macrophages located in subendothelial spaces coupled with endothelial cells induce monocyte and neutrophil tissue infiltration, operating therefore as an anatomical and functional unit. The goals of this Research Topic are (i) to analyze how signal integration and partnering of cell types in transendothelial migration contribute to the development of tissue inflammation and how responses are geared towards specific profiles of reactions to injury; (ii) how the interplay between cell types including, but not limited to, endothelial cells, monocytes, resident macrophages, and T and B cells dynamically governs the immune responses that take place in the tissue; (iii) in which way do integrative capacities of endothelial and subendothelial cells shape and coordinate the successive recruitment of leukocyte populations.



Mechanisms Of Vascular Disease


Mechanisms Of Vascular Disease
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Author : Robert Fitridge
language : en
Publisher: University of Adelaide Press
Release Date : 2011

Mechanisms Of Vascular Disease written by Robert Fitridge and has been published by University of Adelaide Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.


New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.



Platelet Vessel Wall Interactions


Platelet Vessel Wall Interactions
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Author : R. Michael Pittilo
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Platelet Vessel Wall Interactions written by R. Michael Pittilo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The publication of Platelet-Vessel Wall Interactions, the second monograph in the Bloomsbury Series in Clinical Science, is particu larly welcome as its appearance signifies the further development of the Series and its potential for the future. The theme of this monograph is the pathophysiology of atherosclerosis, a topic that symbolises the aim of the Series, namely to highlight the important interfaces between basic medical science and clinical practice. Our congratulations to the Editors and contributors. London, December 1987 lack Tinker Preface In the Western world, atherosclerosis causes more illness and death than any other disease. Despite its devastating effects, the pathogenesis of the disease remains a matter for hypothesis and con jecture. This monograph owes its conception to a programme of work directed towards understanding the basic pathophysiology of atherosclerosis. The circulatory system is lined by vascular endothelium which has a central role in maintaining the integrity of the vessel wall and prevent ing thrombosis. The natural equilibrium existing between normal en dothelium which supports blood flow, and platelets which serve to re pair damaged endothelium, is explored in the first two chapters. Atherosclerosis developing as a response to endothelial injury is one hypothesis which has stimulated widespread interest, and re search has largely been directed towards finding the injurious agent.



Atherosclerosis


Atherosclerosis
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Author : Sergey Fedoroff
language : en
Publisher:
Release Date : 1991-06-01

Atherosclerosis written by Sergey Fedoroff and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-06-01 with categories.