Cell Junctions
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Cell Junctions
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Author : Susan E. La Flamme
language : en
Publisher: John Wiley & Sons
Release Date : 2008-08-08
Cell Junctions written by Susan E. La Flamme and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-08 with Science categories.
This long-awaited, first comprehensive book on this topic of fundamental importance in our understanding of cancer begins with an overview of cellular junctions, before covering cell-matrix junctions, cell-cell junctions and cell-matrix and cell-cell adhesion in separate sections. Of high interest to cell and molecular biologists, cancer researchers, oncologists, biochemists, pharmaceutists and those working in the pharmaceutical industry.
Molecular Mechanisms Of Epithelial Cell Junctions
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Author : Sandra Citi
language : en
Publisher:
Release Date : 1994
Molecular Mechanisms Of Epithelial Cell Junctions written by Sandra Citi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Science categories.
This text examines past and current progress on the structural, biochemical and molecular characterization of specialized cell-cell junctions in various types of epithelial tissue. Special attention is devoted to the recent characterization of specific protein components of junctions, and to questions of structure/function relationships in development, disease and phylogeny in epithelial junctions.
Cell Cell Junctions
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Author : W. James Nelson
language : en
Publisher:
Release Date : 2010
Cell Cell Junctions written by W. James Nelson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
This volume includes contributions covering each of the main junction types as well as the more specialized junctions of neuronal and immune cells. It covers their assembly and structure, importance in signal transduction, and roles in development, normal tissue homeostasis, and diseases.
Parallels In Cell To Cell Junctions In Plants And Animals
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Author : A.W. Robards
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Parallels In Cell To Cell Junctions In Plants And Animals written by A.W. Robards and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
Intracellular junctions provide routes for direct cell-to-cell signalling in both plants and animals. The present volume treats the parallels and differences between such junctions in animals and plants and discusses the most recent methods of examining the physiological functions and regulation of intracellular communication. Strong evidence of both molecular as well as functional simi§ larities between plasmodesmata and gap junctions is increasing. Even more interesting is the discovery that animal gap junction proteins cross-react immunologically with some proteins in plant cells. Thus the molecular construction and function of these crucially important ultrastructural cell components is now open to a concerted research effort to understand how cells, both plant and animal, facilitate and regulate intercellular transport.
Understanding The Types Of Cell Junctions At Molecular Level A Complete Pedagogy
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Author : Dr. Hakim. K. Saboowala
language : en
Publisher: Dr.Hakim Saboowala
Release Date :
Understanding The Types Of Cell Junctions At Molecular Level A Complete Pedagogy written by Dr. Hakim. K. Saboowala and has been published by Dr.Hakim Saboowala this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.
Understanding “The Types of Cell Junctions” at Molecular Level. A Complete Pedagogy. Cell junctions (or intercellular bridges) are a class of cellular structures consisting of multiprotein complexes that provide contact or adhesion between neighboring cells or between a cell and the extracellular matrix in animals. Specialized cell junctions occur at points of cell-cell and cell-matrix contact in all tissues, and they are particularly plentiful in epithelia. Combined with cell adhesion molecules and extracellular matrix, cell junctions help hold animal cells together. Cell junctions are also especially important in enabling communication between neighboring cells via specialized protein complexes called communic- ating (gap) junctions. Cell junctions are also important in reducing stress placed upon cells Cell junctions are best visualized using either conventional or freeze-fracture electron microscopy, which reveals that the interacting plasma membranes (and often the underlying cytoplasm and the intervening intercellular space as well) are highly specialized in these regions. An attempt has been made in this Booklet to discuss the major kinds of Intercellular junctions within each group in turn, except for chemical synapses, which are formed exclusively by nerve cells and are considered in my other Booklet, along with plenty of Diagrams, Images and other relevant ILLUSTRATIONS for better understanding the Topic. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)
Junctional Complexes Of Epithelial Cells
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Author : Gregory R. Bock
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
Junctional Complexes Of Epithelial Cells written by Gregory R. Bock and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Science categories.
Epithelial cells cover the outer and inner surfaces of the body, forming a selective polarized barrier between the intercellualar space and the 'external' world. Linking the cells of this continuous layer and contributing to epithelial organization and function are specialized membrane domains--desmosomes, gap junctions, and occluding junctions. The contributors to this multidisciplinary symposium volume explore the nature of such junctional structures, focusing on the molecular organization and diversity of their constituent proteins, their formation and control, and interactions with ions and cytoskeletal elements. The physiological significance of cell-cell interaction in epithelia is considered, with reference to cell adhesion, barrier formation and intercellular communication, and to the functional implications for tissue architecture, embryonic development, morphogenesis and carcinogenesis.
A Laboratory Guide To The Tight Junction
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Author : Jianghui Hou
language : en
Publisher: Academic Press
Release Date : 2020-04-24
A Laboratory Guide To The Tight Junction written by Jianghui Hou and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-24 with Science categories.
A Laboratory Guide to the Tight Junction offers broad coverage of the unique methods required to investigate its characteristics. The methods are described in detail, including its biochemical and biophysical principles, step-by-step process, data analysis, troubleshooting, and optimization. The coverage includes various cell, tissue, and animal models. Chapter 1 provides the foundations of cell biology of tight junction. Chapter 2 covers the Biochemical approaches for paracellular channels and is followed by chapter 3 providing the Biophysical approaches. Chapter 4 describes and discusses Histological approaches for tissue fixation and preparation. Chapter 5 discusses Light microscopy, while chapter 6 presents Electron microscopic approaches. Chapter 7 covers Transgenic manipulation in cell cultures, including DNA and siRNA, Mutagenesis, and viral infection. Chapter 8 covers transgenic manipulation in mice, including: Knockout, Knockin, siRNA knockdown, GFP/LacZ reporter, and overexpression. The final chapter discusses the future developments of new approaches for tight junction research. Researchers and advanced students in bioscience working on topics of cell junction, ion channel and membrane protein will benefit from the described methods. Clinicians and pathologists interested in tissue barrier diseases will also benefit from the biochemical and biophysical characterization of tight junctions in organ systems, and their connection to human diseases. Provides consistent and detailed research methods Covers various cell, tissue and animal models Includes step-by-step guidance from beginner to sophisticated levels
Gap Junctions Molecular Basis Of Cell Communication In Health And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 1999-12-22
Gap Junctions Molecular Basis Of Cell Communication In Health And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-12-22 with Science categories.
Since the first gap junction protein (connexin) was cloned over a decade ago, more than a dozen connexin genes have been cloned. Consequently, a wealth of information on the molecular basis of gap junctional communication has been accumulated. This book pays tribute to this exciting era in the history of cell communication research by documenting the great strides made in this field as a result of the merging of biophysics and molecular biology, two of the most powerful approaches to studying the molecular basis of membrane channel behavior. Twenty-eight comprehensive chapters, authored by internationally recognized leaders in the field, discuss the biophysical, physiological, and molecular characteristics of cell-to-cell communication via gap junctions. Key aspects of molecular structure, formation, gating, conductance, and permeability of vertebrate and invertebrate gap junction channels are highlighted. In addition, a number of chapters focus on recent discoveries that implicate connexin mutations and alterations of gap junctional communication in the pathogenesis of several diseases, including the X-linked Charcot Marie Tooth demyelinating disease, some forms of inherited sensorineural deafness, malignant transformation, cardiac malformations and arrhythmia, eye lens cataract, and Chagas' disease.
Cell Junctions And Communications
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Author : L. Andrew Staehelin
language : en
Publisher:
Release Date : 1974
Cell Junctions And Communications written by L. Andrew Staehelin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1974 with Cell junctions categories.
Tight Junctions In Inflammation And Cancer
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Author : Ajaz A. Bhat
language : en
Publisher: Springer Nature
Release Date : 2023-10-12
Tight Junctions In Inflammation And Cancer written by Ajaz A. Bhat and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-12 with Science categories.
This book provides an updated account of tight junctions of different epithelia and endothelia and addresses their anatomy, biochemistry, physiology, synthesis, assembly, and modulation. It also discusses the relationship between molecular structure, function, regulation, posttranslational modifications of tight junction proteins and their role in gut microbiota maintenance, epithelial-mesenchymal transition, and intestinal barrier dysfunction-associated disorders important for the progression of human cancers. This book presents the pathological alterations of tight junctions at the blood-brain barrier that intensify or even initiate neurological dysfunction. Further, it reviews the significance of tight junctions and tight junction proteins in cancer development, infectious diseases, allergic reactions, and autoimmune disorders. Lastly, it highlights strategies for modulating tight junctions to enhance drug availability and organ deposition. This book is immensely useful for basic, translational, clinical, and interdisciplinary cancer researchers, practicing oncologists, and immunologists.