Cellular And Molecular Mechanisms Involved In Skeletal Muscle Adaptation
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Cellular And Molecular Mechanisms Involved In Skeletal Muscle Adaptation
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Author : Patrick Oliver James Mitchell
language : en
Publisher:
Release Date : 2003
Cellular And Molecular Mechanisms Involved In Skeletal Muscle Adaptation written by Patrick Oliver James Mitchell and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
Muscle Homeostasis And Regeneration
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Author : Antonio Musarò
language : en
Publisher: MDPI
Release Date : 2020-11-20
Muscle Homeostasis And Regeneration written by Antonio Musarò and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-20 with Science categories.
The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases.
Effect Of Exercise On The Mrna Expression Of Growth Factors Metabolic Genes And Myosin Heavy Chain Isoforms In Skeletal Muscles Of The Rat
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Author : Antonios Matsakas
language : en
Publisher: diplom.de
Release Date : 2004-09-27
Effect Of Exercise On The Mrna Expression Of Growth Factors Metabolic Genes And Myosin Heavy Chain Isoforms In Skeletal Muscles Of The Rat written by Antonios Matsakas and has been published by diplom.de this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-09-27 with Medical categories.
Inhaltsangabe:Abstract: Skeletal muscle is a complex and heterogeneous tissue capable of remarkable adaptation in response to various stimuli such as exercise training. Molecular biology approaches have made a large contribution to our current understanding of how mechanical loading can alter gene expression and muscle protein synthesis rates in skeletal muscle. The steady-state level of a given mRNA is a function of both its rate of synthesis and its rate of degradation, implying that the rate of change in response to a cellular stimulus is dependent on the dynamics of mRNA turnover. Changes in muscle mRNA steady-state levels can be taken as an index of changes in gene expression, constituting currently one of the best described and understood molecular events that underlie muscle plasticity. The discovery of new growth factors involved in the regulation of muscle development provides a better understanding of the molecular mechanisms involved in the adaptation of skeletal muscle to exercise training. Since it has been shown that changes in contractile function can be brought about by switching on one subset and repressing another subset of genes, it was hypothesized that the steady state level of multiple mRNAs (growth factors and metabolic genes) involved in regulatory functions in a muscle which is frequently recruited during exercise is different between endurance trained versus untrained rats. Recent scientific data indicate that myostatin constitutes a limiting factor in normal muscle development playing a crucial role in skeletal muscle hypertrophy. Nevertheless, there are only scarce data so far about the role of myostatin in the exercise-induced skeletal muscle adaptation. The transient changes in regulatory and structural gene expression provide the molecular basis of the adaptability of the skeletal muscle to exercise stimulus. To get an insight into the molecular mechanisms of skeletal muscle adaptation, the main objective of this study was to examine the effect of both the short- and long- term effect of exercise (five day of swimming vs. chronic wheel running) on IGF-I and MSTN (positive and negative skeletal muscle regulators respectively) mRNA contents in male Wistar rats. Potential increase of positive and/or decrease of negative regulators of muscle growth lead to enhanced muscle-progenitor proliferation providing a new perspective in the mechanism of muscle adaptability. It was hypothesized that exercise training could be [...]
The Plasticity Of Skeletal Muscle
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Author : Kunihiro Sakuma
language : en
Publisher: Springer
Release Date : 2017-03-01
The Plasticity Of Skeletal Muscle written by Kunihiro Sakuma and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-01 with Medical categories.
This book discusses recent advances and various topics in plasticity of skeletal muscle from the perspectives of morphology, biological function, and clinical applications. Skeletal muscle is a highly plastic organ to adapt to environmental various demands, appears to endocrine various myokines, which flow into blood to protect the recognizing function of brain and inhibit the appearance of several cancer tumorigenesis. The book deals with current stem-cell based, pharmacological, and nutritional therapies for muscle wasting (sarcopenia, cachexia, and muscular dystrophy). It also explains the roles of biological mediators such as PGC-1, transient receptor potential cation channels (TRPC), and AMPK in modulating muscle function. The functional roles of ubiquitin-proteasome system, autophagy-dependent signaling in muscle homeostasis, ribosome biogenesis, and redox regulation of mechanotransduction to modulate skeletal muscle mass are also covered. It is an essential resource for physicians, researchers, post-docs as well as graduate students in the field of sports science including rehabilitation therapy, exercise physiology, exercise biochemistry, and molecular biology dealing with skeletal muscle.
Molecular And Cellular Exercise Physiology
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Author : Frank Mooren
language : en
Publisher: Human Kinetics Publishers
Release Date : 2005
Molecular And Cellular Exercise Physiology written by Frank Mooren and has been published by Human Kinetics Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
With Molecular and Cellular Exercise Physiology,you'll gain cutting-edge information on how exercise modulates cellular physiology. You'll be able to use that knowledge to develop better training regimens and injury-prevention and rehabilitation programs. You'll also be able to improve performance. The book is unique in that it is the first comprehensive text to address the effects of physical activity on the cellular and molecular level. Molecular and Cellular Exercise Physiologyhighlights the potential of physical training in the prevention and treatment of chronic diseases while thoroughly exploring these topics: -Fundamental cellular and molecular mechanisms responsible for changes in stroke volume, blood gas homeostasis, pH alterations, blood pressure, and osmosis in response to exercise -How the exercise effects are mediated and translated into specific cellular and subcellular alterations Recent fascinating advances in molecular techniques have extended the field of exercise physiology and enabled researchers to address the mechanisms involved on a subcellular and molecular level. Molecular and Cellular Exercise Physiologyis a vital reference to help you stay on top of this exciting field.
Genetics And Molecular Biology Of Muscle Adaptation
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Author : Neil Spurway
language : en
Publisher: Elsevier Health Sciences
Release Date : 2006-01-01
Genetics And Molecular Biology Of Muscle Adaptation written by Neil Spurway and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-01 with Medical categories.
This title is directed primarily towards health care professionals outside of the United States. It starts with the origin of life and ends with the mechanisms that make muscles adapt to different forms of training. In between, it considers how evidence has been obtained about the extent of genetic influence on human capacities, how muscles and their fibres are studied for general properties and individual differences, and how molecular biological techniques have been combined with physiological ones to produce the new discipline of molecular exercise physiology. This is the first book on such topics written specifically for modules in exercise and sport science at final year Hons BSc and taught MSc levels.
Muscle Homeostasis And Regeneration
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Author : Antonio Musarò
language : en
Publisher:
Release Date : 2020
Muscle Homeostasis And Regeneration written by Antonio Musarò and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases.
Physical Activity Fitness And Health
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Author : Claude Bouchard
language : en
Publisher: Champaign, IL : Human Kinetics Publishers
Release Date : 1994
Physical Activity Fitness And Health written by Claude Bouchard and has been published by Champaign, IL : Human Kinetics Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Health & Fitness categories.
Can health-care costs be reduced by increasing the overall level of physical activity? What part does heredity play in physical fitness? How does exercise affect the immune system? What is the relationship between physical activity and hypertension?
Muscle Cell And Tissue
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Author : Kunihiro Sakuma
language : en
Publisher:
Release Date : 2021
Muscle Cell And Tissue written by Kunihiro Sakuma and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Muscles categories.
The loss of skeletal muscle mass and strength substantially impairs physical performance and quality of life. This book details some approaches to the treatment of muscle wasting. It also reviews novel applications against pulmonary arterial hypertension such as cell reprogramming and the use of anticancer drugs that induce programmed cell death. Vascular smooth muscle cells (VSMCs) are the most prevalent cell types in blood vessels and serve critical regulatory roles. This publication also introduces mathematical models concerning the molecular mechanism and targets of cyclic guanosine 3'2,5'2-monophosphate (cGMP) in the contraction of VSMCs. This book will be of interest to professionals in clinical practice, medical and health care students, and researchers working in muscle-related fields of science.
Exercise Metabolism
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Author : Mark Hargreaves
language : en
Publisher: Human Kinetics
Release Date : 2006
Exercise Metabolism written by Mark Hargreaves and has been published by Human Kinetics this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Energy metabolism categories.
A comprehensive reference for biochemists, sport nutritionists, exercise physiologists, and graduate students in those disciplines. Provides information on the metabolic processes that take place during exercise, examining in depth the mobilization and utilization of substrates during physical activity. Focuses primarily on the skeletal muscle, but also discusses the roles of the liver and adipose tissue. Annotation copyright by Book News, Inc., Portland, OR