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Chimeric Rna


Chimeric Rna
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Chimeric Rna


Chimeric Rna
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Author : Hui Li
language : en
Publisher: Humana
Release Date : 2020-11-28

Chimeric Rna written by Hui Li and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-28 with Science categories.


This book provides numerous methods for identification, validation, and functional characterization of chimeric RNAs, herein described as any transcript which contains the nucleotide sequence of two distinct parental genes. Beginning with identification and characterization through bioinformatics tools, the book continues with experimental validation using RT-PCR, hybridization methods for RNA, and the use of mass spectrometry data for fusion protein validation, as well as functional and mechanistic studies of chimeric RNAs and translational applications. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Chimeric RNA: Methods and Protocols is an ideal guide to this expansive field and an inspiration to researchers seeking to further our knowledge of these remarkable features of the transcriptome.



Applications Of Chimeric Genes And Hybrid Proteins Part C Protein Protein Interactions And Genomics


Applications Of Chimeric Genes And Hybrid Proteins Part C Protein Protein Interactions And Genomics
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Author :
language : en
Publisher: Elsevier
Release Date : 2000-10-28

Applications Of Chimeric Genes And Hybrid Proteins Part C Protein Protein Interactions And Genomics written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-10-28 with Science categories.


The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.



Biophysical Chemical And Functional Probes Of Rna Structure Interactions And Folding


Biophysical Chemical And Functional Probes Of Rna Structure Interactions And Folding
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Author : Daniel Herschlag
language : en
Publisher: Academic Press
Release Date : 2009-11-16

Biophysical Chemical And Functional Probes Of Rna Structure Interactions And Folding written by Daniel Herschlag and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-16 with Science categories.


This MIE volume provides laboratory techniques that aim to predict the structure of a protein which can have tremendous implications ranging from drug design, to cellular pathways and their dynamics, to viral entry into cells. Expert researchers introduce the most advanced technologies and techniques in protein structure and folding Includes techniques on tiling assays



Rna Based Regulation In Human Health And Disease


Rna Based Regulation In Human Health And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-08-19

Rna Based Regulation In Human Health And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-19 with Medical categories.


RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics. Comprehensive information of non-canonical RNA-based genome regulation modulating human health and disease Defines RNA classes with special emphasis on unexplored world of noncoding RNA at different hierarchies Disease specific role of RNA - causal, prognostic, diagnostic and therapeutic Features contributions from leading experts in the field



Rna 3 End Formation In Retroviruses


Rna 3 End Formation In Retroviruses
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Author : Kouichi Iwasaki
language : en
Publisher:
Release Date : 1991

Rna 3 End Formation In Retroviruses written by Kouichi Iwasaki and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with categories.




Rna Biology Of Microorganisms


Rna Biology Of Microorganisms
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Author : Omar Orellana
language : en
Publisher: Frontiers Media SA
Release Date : 2021-12-31

Rna Biology Of Microorganisms written by Omar Orellana and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-31 with Science categories.




Rna Nanotechnology And Therapeutics


Rna Nanotechnology And Therapeutics
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Author : Peixuan Guo
language : en
Publisher: CRC Press
Release Date : 2022-07-18

Rna Nanotechnology And Therapeutics written by Peixuan Guo and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-18 with Medical categories.


Interest in RNA nanotechnology has increased in recent years as recognition of its potential for applications in nanomedicine has grown. Edited by the world's foremost experts in nanomedicine, this comprehensive, state-of-the-art reference details the latest research developments and challenges in the biophysical and single molecule approaches in RNA nanotechnology. In addition, the text also provides in-depth discussions of RNA structure for nanoparticle construction, RNA computation and modeling, single molecule imaging of RNA, RNA nanoparticle assembly, RNA nanoparticles in therapeutics, immunorecognition of RNA nanomaterials, RNA chemistry for nanoparticle synthesis, and conjugation and labeling. Presents the latest research and discoveries in RNA nanotechnology Features contributions from world-class experts in the field Covers RNA nanoparticles in therapeutics Describes self-assembled RNA nanoparticles



Rna Trafficking And Nuclear Structure Dynamics


Rna Trafficking And Nuclear Structure Dynamics
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Author : Philippe Jeanteur
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-01-14

Rna Trafficking And Nuclear Structure Dynamics written by Philippe Jeanteur and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-14 with Science categories.


This volume explores nuclear structure and trafficking involving or relevant to RNA and RNPs. Topics include advances and current problems in the structural organization of different subnuclear compartments, Cajal bodies and gems, speckles containing splicing factors, and PML bodies characteristic of ProMyelocytic leukemia. The book also describes the dynamic aspects of RNA trafficking and the latest technologies for live cell imaging of mRNA.



Integrated Drug Discovery Technologies


Integrated Drug Discovery Technologies
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Author : Houng-Yau Mei
language : en
Publisher: CRC Press
Release Date : 2002-03-19

Integrated Drug Discovery Technologies written by Houng-Yau Mei and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-03-19 with Science categories.


Integrated Drug Discovery Technologies provides a global overview of emerging drug development technologies by presenting and integrating new techniques from the disciplines of chemistry, biology, and computational sciences. It combines integration of contemporary mechanization with strategies in drug delivery. Topics include: functional genomics, microfabrication techniqes, integrated proteomics technologies, high throughput screening, and fluorescence correlation spectroscopy methods.



Duchenne Muscular Dystrophy


Duchenne Muscular Dystrophy
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Author : Jeffrey S. Chamberlain
language : en
Publisher: CRC Press
Release Date : 2006-02-27

Duchenne Muscular Dystrophy written by Jeffrey S. Chamberlain and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-02-27 with Medical categories.


Duchenne Muscular Dystrophy (DMD) is one of the most prevalent genetic disorders of childhood for which there is no cure. This authoritative guide provides a clear overview of the clinical, genetic, and pathophysiological aspects of the disease in the context of emerging therapeutic modalities. The only available source on the subject, this reference emphasizes the importance of accurate diagnosis, carrier detection, and genetic counseling, and supplies state-of-the-art information on pharmacological interventions, regenerative medicine, and gene therapy.