Chiral Building Blocks In Asymmetric Synthesis
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Chiral Building Blocks In Asymmetric Synthesis
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Author : Jacek Wojaczynski
language : en
Publisher: John Wiley & Sons
Release Date : 2022-08-05
Chiral Building Blocks In Asymmetric Synthesis written by Jacek Wojaczynski and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-05 with Science categories.
Chiral Building Blocks in Asymmetric Synthesis A comprehensive introduction to the important classes of chiral building blocks Chirality — the asymmetric quality found in certain chemical compounds — plays an essential role in our world: chiral compounds can be found in biology, pharmaceutical compounds, agrochemicals, and fragrances. The stereoselective preparation of these complex molecular constructions constitutes a challenge. To this end, modern asymmetric synthesis utilizes a variety of valuable and efficient reagents employed as chiral auxiliaries, metal complexes and organocatalysts in stereoselective catalysis, and enantiopure reactants termed as chiral building blocks. In Chiral Building Blocks in Asymmetric Synthesis, the achievements in the fields of preparation of and applications of chiral blocks are presented. In doing so, the book comprehensively discusses the important classes of these reactants as the key for the asymmetric synthesis of chiral molecules. As such, it is an indispensable resource about synthetic methods, as well as possible modifications and transformations of important classes of chiral compounds. It also highlights the importance of their use as reactants and auxiliaries in the preparation of more sophisticated molecules or supramolecular systems. In Chiral Building Blocks in Asymmetric Synthesis readers will also find: Organization according to the most important compound classes — e.g. amino acids, BINOL and its derivatives, terpenes, and others — with an emphasis on synthesis and application A focus on the use of chiral building blocks for the preparation of bioactive compounds and supramolecular assemblies Chiral Building Blocks in Asymmetric Synthesis is a useful reference for organic chemists, catalytic chemists, chemists in industry, medicinal chemists, pharmaceutical chemists, and the libraries that support them.
Asymmetric Synthesis V4
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Author : James Morrison
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Asymmetric Synthesis V4 written by James Morrison and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Asymmetric Synthesis, Volume 4: The Chiral Carbon Pool and Chiral Sulfur, Nitrogen, Phosphorus, and Silicon Centers describes the practical methods of obtaining chiral fragments. Divided into five chapters, this book specifically examines initial chiral transmission and extension. The opening chapter describes the so-called chiral carbon pool, the readily available chiral carbon fragments used as building blocks in synthesis. This chapter also provides a list of 375 chiral building blocks, along with their commercial sources, approximate prices, and methods of synthesis. Schemes involving almost 1,300 structures and the use of chiral building blocks to prepare alkaloids, arachidonic acid metabolites, compounds with chemotherapeutic and pharmacological activity, insect pheromones, sugars, vitamins, terpenoids, and miscellaneous compounds are also included in this text. The remaining chapters provide a similar overview of the chemistry of compounds chiral at sulfur, phosphorus, nitrogen, and silicon. Synthetic chemists and researchers, especially those engaged in pharmaceutical research and specialty chemicals production, will find this book invaluable.
The Chiral Carbon Pool And Chiral Sulfur Nitrogen Phosphorus And Silicon Centers
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Author : James D. Morrison
language : en
Publisher:
Release Date : 1984
The Chiral Carbon Pool And Chiral Sulfur Nitrogen Phosphorus And Silicon Centers written by James D. Morrison and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Science categories.
Asymmetric Synthesis, Volume 4: The Chiral Carbon Pool and Chiral Sulfur, Nitrogen, Phosphorus, and Silicon Centers describes the practical methods of obtaining chiral fragments. Divided into five chapters, this book specifically examines initial chiral transmission and extension. The opening chapter describes the so-called chiral carbon pool, the readily available chiral carbon fragments used as building blocks in synthesis. This chapter also provides a list of 375 chiral building blocks, along with their commercial sources, approximate prices, and methods of synthesis. Schemes involving almo ...
Tartaric And Malic Acids In Synthesis
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Author : Jacek Gawronski
language : en
Publisher: John Wiley & Sons
Release Date : 1999-02-17
Tartaric And Malic Acids In Synthesis written by Jacek Gawronski and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-02-17 with Science categories.
Weinsäure- und Äpfelsäurederivate sind sehr nützliche Bausteine für die asymmetrische Synthese von großen organischen Molekülen. Diese sog. enantioselektiven Synthesen sind von größter Bedeutung in der Naturstoff-Forschung sowie in der Feinchemie und pharmazeutischen Industrie. Dieses Buch liefert einen genauen und umfassenden Überblick über die chemischen Eigenschaften und synthetischen Anwendungen aller Derivate der Wein- und Äpfelsäure. Ideal für alle, die auf diesem Gebiet arbeiten. Auch für Studenten! Es enthält Hunderte chemischer Reaktionen, 50 große Tabellen und 2.000 Verweise: Eine erschöpfende Behandlung von Struktur, Eigenschaften und synthetischen Anwendungen von 20 Derivatklassen der Wein- und Äpfelsäure. (02/99)
Principles And Applications Of Asymmetric Synthesis
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Author : Guo-Qiang Lin
language : en
Publisher: John Wiley & Sons
Release Date : 2003-05-29
Principles And Applications Of Asymmetric Synthesis written by Guo-Qiang Lin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-05-29 with Science categories.
Asymmetric synthesis remains a challenge to practicing scientistsas the need for enantiomerically pure or enriched compoundscontinues to increase. Over the last decade, a large amount ofliterature has been published in this field. Principles andApplications of Asymmetric Synthesis consolidates and evaluates themost useful methodologies into a one-volume resource for theconvenience of practicing scientists and students. Authored by internationally renowned scientists in the field, thisreliable reference covers more than 450 reactions and includesimportant stoichiometric as well as catalytic asymmetric reactions.The first chapter reviews the basic principles, commonnomenclature, and analytical methods, and the remainder of the bookis organized according to reaction type. The text examines suchtopics as: Carbon-carbon bond formations involving carbonyls, enamines,imines, and enolates Asymmetric C-O bond formations including epoxidation,dihydroxylation, and aminohydroxylation Asymmetric synthesis using the Diels-Alder reaction and othercyclizations Applications to the total synthesis of natural products Use of enzymes in asymmetric synthesis Practicing chemists in the pharmaceutical, fine chemical, andagricultural professions as well as graduate students will findthat Principles and Applications of Asymmetric Synthesis affordscomprehensive and current coverage.
Asymmetric Organocatalysis
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Author : Albrecht Berkessel
language : en
Publisher: Wiley-VCH
Release Date : 2006-03-06
Asymmetric Organocatalysis written by Albrecht Berkessel and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Science categories.
Asymmetric catalysis represents still one of the major challenges in modern organic chemistry. Besides the well-established asymmetric metal-complex-catalysed syntheses and biocatalysis, the use of "pure" organic catalysts turned out to be an additional efficient tool for the synthesis of chiral building blocks. In this handbook, the experienced authors from academia and industry provide the first overview of the important use of such metal-free organic catalysts in organic chemistry. With its comprehensive description of numerous reaction types, e.g., nucleophilic substitution and addition reactions as well as cycloadditions and redox reactions, this book targets organic chemists working in industry and academia, and deserves a place in every laboratory.
Asymmetric Synthesis
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Author : Alan Aitken
language : en
Publisher: CRC Press
Release Date : 1992-12-30
Asymmetric Synthesis written by Alan Aitken and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-12-30 with Science categories.
Asymmetric synthesis is one of the most important areas of research and development in synthetic organic chemistry, and has wide-ranging industrial applications. This introduction to the subject covers chirality, nomenclature and analytical methods of resolution. The main body of the text describes the principal methods available to the organic chemist wishing to synthesize chiral compounds. Case studies are included, and reference sections allow access to the relevant review and research literature. This book is written for organic chemists at postgraduate and advanced undergraduate level.
Principles Of Asymmetric Synthesis
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Author : Robert E. Gawley
language : en
Publisher: Elsevier
Release Date : 2012-07-16
Principles Of Asymmetric Synthesis written by Robert E. Gawley and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-16 with Science categories.
The world is chiral. Most of the molecules in it are chiral, and asymmetric synthesis is an important means by which enantiopure chiral molecules may be obtained for study and sale. The aim of this book is to present a detailed analysis of the factors that govern stereoselectivity in organic reactions.
Organic Chemistry From Retrosynthesis To Asymmetric Synthesis
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Author : Vitomir Šunjić
language : en
Publisher: Springer
Release Date : 2016-04-30
Organic Chemistry From Retrosynthesis To Asymmetric Synthesis written by Vitomir Šunjić and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-30 with Science categories.
This book connects a retrosynthetic or disconnection approach with synthetic methods in the preparation of target molecules from simple, achiral ones to complex, chiral structures in the optically pure form. Retrosynthetic considerations and asymmetric syntheses are presented as closely related topics, often in the same chapter, underlining the importance of retrosynthetic consideration of target molecules neglecting stereochemistry and equipping readers to overcome the difficulties they may encounter in the planning and experimental implementation of asymmetric syntheses. This approach prepares students in advanced organic chemistry courses, and in particular young scientists working at academic and industrial laboratories, for independently solving synthetic problems and creating proposals for the synthesis of complex structures.
Advances In Asymmetric Synthesis
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Author :
language : en
Publisher: Elsevier
Release Date : 1995-03-01
Advances In Asymmetric Synthesis written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-03-01 with Science categories.
Advances in Asymmetric Synthesis