Chiral Reagents For Asymmetric Synthesis

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Chiral Reagents For Asymmetric Synthesis
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Author : Leo A. Paquette
language : en
Publisher: John Wiley & Sons
Release Date : 2003-08-01
Chiral Reagents For Asymmetric Synthesis written by Leo A. Paquette and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-08-01 with Science categories.
Derived from the renowned, Encyclopedia of Reagents for Organic Synthesis (EROS), the related editors have created a new handbook which focuses on chiral reagents used in asymmetric synthesis and is designed for the chemist at the bench. This new handbook follows the same format as the Encyclopedia, including an introduction and an alphabetical arrangement of the reagents. As chiral reagents are the key for the successful asymmetric synthesis, choosing the right reagents is essential, in this handy reference the editors give details on how to prepare, store and use the reagents as well as providing key reactions to demonstrate where reagents have been successfully used. Comprehensive information on 226 reagents Covers 64 reagents which were not included in EROS All information in one easy to use volume – at an affordable price All reagents included will be added to e-EROS – please visit the site where you can gain access to over 50,000 reactions and 3,800 of the most frequently consulted reagents. Visit: www.interscience.wiley.com/eros
Handbook Of Reagents For Organic Synthesis Chiral Reagents For Asymmetric Synthesis
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Author : Leo A. Paquette
language : en
Publisher:
Release Date : 2003
Handbook Of Reagents For Organic Synthesis Chiral Reagents For Asymmetric Synthesis written by Leo A. Paquette and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Chemical tests and reagents categories.
Handbook Of Chiral Chemicals
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Author : David Ager
language : en
Publisher: CRC Press
Release Date : 2005-10-21
Handbook Of Chiral Chemicals written by David Ager and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-21 with Medical categories.
As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. "The Handbook of Chiral Chemicals, Second Edition" highlights the problems associated with the production of chiral compounds on a commercial scale. The handbook fir
Handbook Of Reagents For Organic Synthesis Chiral Reagents For Asymmetric Synthesis
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Author :
language : en
Publisher:
Release Date : 1999
Handbook Of Reagents For Organic Synthesis Chiral Reagents For Asymmetric Synthesis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Chemical tests and reagents categories.
Chiral Auxiliaries And Ligands In Asymmetric Synthesis
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Author : J. Seyden-Penne
language : en
Publisher: Wiley-Interscience
Release Date : 1995-10-23
Chiral Auxiliaries And Ligands In Asymmetric Synthesis written by J. Seyden-Penne and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-10-23 with Science categories.
Table of Contents Preface Abbreviations Introduction 1 1 Enantiomerically Pure Chiral Auxiliaries 43 2 Chiral Reagents 87 3 Chiral Catalysis and Catalysts Bearing Chiral Ligands 117 4 Asymmetric Deprotonations and Protonations 143 5 Alkylations and Related Reactions 157 6 Additions to C=O and C=N Double Bonds 209 7 Additions to Carbon-Carbon Double Bonds 367 8 Additions to Double Bonds Bearing Heteroatoms. Oxidations of Sulfides and Selenides 503 9 Cycloadditions 513 10 Sigmatropic Rearrangements 593 11 Transition Metal Catalyzed Reactions 619 References 637 Index 707.
Chiral Building Blocks In Asymmetric Synthesis
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Author : Elzbieta Wojaczynska
language : en
Publisher: John Wiley & Sons
Release Date : 2022-08-08
Chiral Building Blocks In Asymmetric Synthesis written by Elzbieta Wojaczynska and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-08 with Science categories.
Chiral Building Blocks in Asymmetric Synthesis A comprehensive introduction to the important classes of chiral building blocks Chirality — the asymmetric quality found in certain chemical compounds — plays an essential role in our world: chiral compounds can be found in biology, pharmaceutical compounds, agrochemicals, and fragrances. The stereoselective preparation of these complex molecular constructions constitutes a challenge. To this end, modern asymmetric synthesis utilizes a variety of valuable and efficient reagents employed as chiral auxiliaries, metal complexes and organocatalysts in stereoselective catalysis, and enantiopure reactants termed as chiral building blocks. In Chiral Building Blocks in Asymmetric Synthesis, the achievements in the fields of preparation of and applications of chiral blocks are presented. In doing so, the book comprehensively discusses the important classes of these reactants as the key for the asymmetric synthesis of chiral molecules. As such, it is an indispensable resource about synthetic methods, as well as possible modifications and transformations of important classes of chiral compounds. It also highlights the importance of their use as reactants and auxiliaries in the preparation of more sophisticated molecules or supramolecular systems. In Chiral Building Blocks in Asymmetric Synthesis readers will also find: Organization according to the most important compound classes — e.g. amino acids, BINOL and its derivatives, terpenes, and others — with an emphasis on synthesis and application A focus on the use of chiral building blocks for the preparation of bioactive compounds and supramolecular assemblies Chiral Building Blocks in Asymmetric Synthesis is a useful reference for organic chemists, catalytic chemists, chemists in industry, medicinal chemists, pharmaceutical chemists, and the libraries that support them.
Organosilicon Compounds
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Author : Vladimir Ya Lee
language : en
Publisher: Academic Press
Release Date : 2017-08-22
Organosilicon Compounds written by Vladimir Ya Lee and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-22 with Science categories.
Organosilicon Compounds: Theory and Experiment (Synthesis), volume 1, comprises two parts. The first part, Theory, covers state-of-the-art computational treatments of unusual nonstandard organosilicon compounds that classical bonding theory fails to describe adequately. The second part, Experiment (Synthesis), describes recent synthetic advances in the preparation of a variety of organosilicon compounds with different coordination numbers of the central silicon: from tetracoordinate to low-coordinate to hypercoordinate derivatives. Organosilicon Compounds: From Theory to Synthesis to Applications provides a comprehensive overview of this important area of organic and organometallic chemistry, dealing with compounds containing carbon–silicon bonds. This field, which includes compounds that are widely encountered in commercial products such as in the fabrication of sealants, adhesives, and coatings, has seen many milestone discoveries reported during the last two decades. Beginning with the theoretical aspects of organosilicon compounds' structure and bonding, the book then explores their synthetic aspects, including main group element organosilicon compounds, transition metal complexes, silicon cages and clusters, low-coordinate organosilicon derivatives (cations, radicals, anions, multiple bonds to silicon, silaaromatics), and more. Next, readers will find valuable sections that explore physical and chemical properties of organosilicon compounds by means of X-ray crystallography, 29Si NMR spectroscopy, photoelectron spectroscopy, and other methods. Finally, the work delves into applications for industrial uses and in many related fields, such as polymers, material science, nanotechnology, bioorganics, and medicinal silicon chemistry. - Features valuable contributions from prominent experts that cover both fundamental (theoretical, synthetic, physico-chemical) and applied (material science, applications) aspects of modern organosilicon chemistry - Covers important breakthroughs in the field, along with the historically significant achievements of the past - Includes applied information for a wide range of specialists, from junior and senior researchers (from both academia and industry) - Ideal reference for those working in organometallic, organosilicon, main group element, transition metal, and industrial silicon chemistry, as well as those from interdisciplinary fields, such as polymer, material science, and nanotechnology
Atropisomerism And Axial Chirality
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Author : Jose M Lassaletta
language : en
Publisher: World Scientific
Release Date : 2019-05-23
Atropisomerism And Axial Chirality written by Jose M Lassaletta and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-23 with Science categories.
Chapter contribution from Ben Feringa, Nobel Laureate in Chemistry 2016.Atropisomerism and Axial Chirality provides a global survey of the chemistry of axially chiral compounds including biaryls, heterobiaryls, non-biaryl atropisomers, allenes and spyrocyclic derivatives. From the perspective of a synthetic organic chemist, this book provides a unique compilation of the available methodologies for their synthesis, with emphasis on the most efficient and modern strategies, a review of the huge amount of practical applications in the field of asymmetric catalysis, either as transition metal ligands or as organocatalysts, and an overview of their occurrence as bioactive compounds and natural products.The first of its kind, this book serves as a general introduction and a practical reference to advanced chemistry students and researchers, while also offering creative ideas for further developments in the field.
Chiral Drugs
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Author : Guo-Qiang Lin
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-08
Chiral Drugs written by Guo-Qiang Lin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-08 with Science categories.
An integrated view of chiral drugs from concept and synthesisto pharmaceutical properties Chirality greatly influences a drug's biological and pharmacological properties. In an effort to achieve more predictable results from chiral drugs, the Food and Drug Administration now requires that these medicines be as pure as possible, which places great demands on drug synthesis, purification, analysis, and testing. To assist researchers in acquiring the essential knowledge to meet these rigid guidelines, Chiral Drugs focuses on three vital chiral technologies asymmetric synthesis, biocatalytic process, and chiral resolution to offer details on the basic concepts, key developments, and recent trends in chiral drug discovery, along with: The history of chiral drugs development and industrial applications of chiral technologies A section listing twenty-five approved or advanced-trial chiral drugs that lists each drug name, chemical name and properties, a representative synthetic pathway, pharmacological characterizations, and references An interdisciplinary approach combining synthetic organic chemistry, medicinal chemistry, and pharmacology Nearly two-thirds of the drugs on today's market are chiral drugs. Reducing and eliminating their negative characteristics is an ongoing and serious challenge for the pharmaceutical industry. With its well-balanced approach to covering each important aspect of chirality, Chiral Drugs champions important strategies for tipping the medical scale in a positive direction for the production of more effective and safer drugs.
Chirogenesis In Chemical Science
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Author : Victor Borovkov
language : en
Publisher: World Scientific
Release Date : 2022-12-28
Chirogenesis In Chemical Science written by Victor Borovkov and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-28 with Science categories.
Chirogenesis in Chemical Science is an exciting new book that takes readers inside the world of chirality and chirogenesis, guided by Victor Borovkov and Riina Aav, both internationally renowned experts on chirality. Chirality is a fundamental property of the universe and has significance in different organic/inorganic materials, living organisms, and human beings. The basic principle of chirality is existence of an object in two mirror image forms, which are not superimposable. This phenomenon is widely seen in various fields of knowledge including mathematics, astronomy, physics, chemistry, biology and ranging in scale from galaxies to nuclear particles.In chemical science, chirality is generally associated with a single molecule or group of molecules, which symmetry properties belonging to the Cn or Dn point groups with the simplest example of sp3 carbon atom bonded to four different substituents. The dynamic processes of chirality generation, modulation, transfer, amplification, etc. are termed chirogenesis.This is a fast-growing and interdisciplinary field of research, which is widely seen in many natural systems (such as DNA double helix, the secondary alpha-helix structure of proteins, lipid membranes, saccharides, heme proteins, and other biological molecular objects) and various artificial systems. It is of prime importance not only for fundamental science but also for a number of practical applications in such areas as pharmacology and agrochemistry, perfumery and food industry, materials and polymer sciences, enantioselective catalysis and nonlinear optics, nanoscience and nanotechnology, molecular devices and chemical sensors, and others. Therefore, understanding the mechanisms and various influencing factors is of particular significance for smart control and further effective application of chirogenesis in chemistry.