Chiral Separations And Stereochemical Elucidation
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Chiral Separations And Stereochemical Elucidation
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Author : Quezia Bezerra Cass
language : en
Publisher: John Wiley & Sons
Release Date : 2023-05-09
Chiral Separations And Stereochemical Elucidation written by Quezia Bezerra Cass and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-09 with Science categories.
An expert resource for chemists using stereochemical analysis methods In Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications, a team of distinguished researchers delivers a robust and authoritative discussion of the theoretical fundamentals of chiral separation, the most commonly used chiral selectors, and stereochemical elucidation methods. The book offers expert discussions of a variety of chiral separation methods by gas chromatography (GC), supercritical fluid chromatography (SFC), capillary electrophoresis (CE), and liquid chromatography (LC). The authors also describe several methods for stereochemical elucidation, including X-ray crystallography, nuclear magnetic resonance spectroscopy, and chiroptical methods. The explored material is ideal for practicing chemists seeking a resource to help them guide method development and optimization or to explain quality control-complements during target compound production. Readers will also find: A thorough introduction to the most important advances and applications in LC, GC, CE, SFC, and preparative chromatography Comprehensive explorations of the role of 2D-LC for chiral separation methods development and applications Practical discussions of the design, mechanisms, and applications of the most commonly used chiral selectors Fulsome treatments of the theoretical backgrounds, advantages, limitations, and applications of stereochemical elucidation methods Perfect for academic and industrial chemists specially in organic, analytical chemistry and pharmaceutical analysis. Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications will also benefit biochemists, environmental analysts, forensic and medicinal chemists as well as natural product chemists and those involved with stereochemistry or structural elucidation.
Chiral Separation Techniques
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Author : G. Subramanian
language : en
Publisher: Wiley-VCH
Release Date : 2001
Chiral Separation Techniques written by G. Subramanian and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Science categories.
This is a completely revised and updated sequel to 'A Practical Approach to Chiral Separations by Liquid Chromatography' by the same editor. The scope has been extended to further chiral separation techniques like electrophoresis, membrane separations, or biological assays. More emphasis is put on preparative separation techniques. From reviews of the previous edition: 'A team of experts from academic and industrial laboratories throughout the world have compiled their findings and experience to make this book an exceptionally timely and unique contribution to the field' European Journal of Drug Metabolism 'The dense mass of information contained in this book will make it a valuable resource ...' Chemical Engineering Research '... this is a worthwhile addition to the expanding chiral literature and the book should be of value to those working in this field' The Analyst
Chiral Separations And Stereochemical Elucidation
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Author : Quezia Bezerra Cass
language : en
Publisher: John Wiley & Sons
Release Date : 2023-03-29
Chiral Separations And Stereochemical Elucidation written by Quezia Bezerra Cass and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-29 with Science categories.
An expert resource for chemists using stereochemical analysis methods In Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications, a team of distinguished researchers delivers a robust and authoritative discussion of the theoretical fundamentals of chiral separation, the most commonly used chiral selectors, and stereochemical elucidation methods. The book offers expert discussions of a variety of chiral separation methods by gas chromatography (GC), supercritical fluid chromatography (SFC), capillary electrophoresis (CE), and liquid chromatography (LC). The authors also describe several methods for stereochemical elucidation, including X-ray crystallography, nuclear magnetic resonance spectroscopy, and chiroptical methods. The explored material is ideal for practicing chemists seeking a resource to help them guide method development and optimization or to explain quality control-complements during target compound production. Readers will also find: A thorough introduction to the most important advances and applications in LC, GC, CE, SFC, and preparative chromatography Comprehensive explorations of the role of 2D-LC for chiral separation methods development and applications Practical discussions of the design, mechanisms, and applications of the most commonly used chiral selectors Fulsome treatments of the theoretical backgrounds, advantages, limitations, and applications of stereochemical elucidation methods Perfect for academic and industrial chemists specially in organic, analytical chemistry and pharmaceutical analysis. Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications will also benefit biochemists, environmental analysts, forensic and medicinal chemists as well as natural product chemists and those involved with stereochemistry or structural elucidation.
Chiral Separation Techniques
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Author : Ganapathy Subramanian
language : en
Publisher: Wiley-VCH
Release Date : 2001-10-18
Chiral Separation Techniques written by Ganapathy Subramanian and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-18 with Science categories.
This is a completely revised and updated sequel to 'A Practical Approach to Chiral Separations by Liquid Chromatography' by the same editor. The scope has been extended to further chiral separation techniques like electrophoresis, membrane separations, or biological assays. More emphasis is put on preparative separation techniques. From reviews of the previous edition: 'A team of experts from academic and industrial laboratories throughout the world have compiled their findings and experience to make this book an exceptionally timely and unique contribution to the field' European Journal of Drug Metabolism 'The dense mass of information contained in this book will make it a valuable resource ...' Chemical Engineering Research '... this is a worthwhile addition to the expanding chiral literature and the book should be of value to those working in this field' The Analyst
Chiral Separations
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Author : D. Stevenson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Chiral Separations written by D. Stevenson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This volume represents the proceedings of a two-day international meeting on chiral chromatography held at the University of Surrey between 3-4 September 1987. The meeting was jointly organized by the Chromatographic SOCiety and the Robens Institute of the University of Surrey in response to the burgeoning interest in this rapid maturing field of chromatography. Nowhere is this interest more evident than in the agrochemical and pharmaceutical industries where the implications of different pharmacological and toxicological activity for the individual enantiomers present in a racemic drug ol" insecticide is an increasing area of concern. Developments in the area of chiral separations are at last beginning to provide SCientists with the necessary tools to study how animals and man handle racemates and relate their obseIVations to the obseIVed biological effects of these substances. The development of robust and Simple methods for the separation of enantiomers will therefore have a profound Impact on safety evaluation and drug design. The meeting proved to be very successful. with over 160 delegates from thirteen countries in Europe and America present to learn from the experiences of experts in the field of chiral chromatography and to hear about the latest developments. Hopefully. in future symposia on chiral separations at the University of Surrey.
Stereochemistry
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Author : Anil V. Karnik
language : en
Publisher: Elsevier
Release Date : 2021-07-21
Stereochemistry written by Anil V. Karnik and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-21 with Science categories.
Stereochemistry: A Three-Dimensional Insight draws on the knowledge of its expert authors, providing a systematic treatment on the fundamental aspects of stereochemistry, covering conformational aspects, configurational aspects, effects of bulkiness, stereoelectronic effects on properties of molecules, and the genesis of enantiomerism, among other topics. Visuals and exercises are included to consolidate the principles learned, and the contents are carefully structured to prepare readers for predicting and organizing reaction components to obtain desired stereochemical outcomes. This book is an indispensable guide for all those exploring stereochemistry within their work. The principles of stereochemistry are fundamental to understanding chemical behavior and can provide insights into a whole range of problems, from unusual selectivity and unexpected behaviors, to abnormally fast reactions and surprising biochemical preferences. However, understanding and exploring these 3D effects can be difficult within a 2D medium. This book has been designed to address this problem, providing foundational guidance on the principles and applications of stereochemistry that are fully supported by multimedia visuals. Combines foundational concepts and definitions with examples of stereochemistry in practice Highlights the conformational and configurational impact of atomic arrangement on chemical behavior Outlines methods of analysis Provides practical exercises and detailed multimedia visuals to support learning
Dynamic Stereochemistry Of Chiral Compounds
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Author : Christian Wolf
language : en
Publisher: Royal Society of Chemistry
Release Date : 2008
Dynamic Stereochemistry Of Chiral Compounds written by Christian Wolf and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Education categories.
A comprehensive overview of fundamental concepts of asymmetric synthesis along with in-depth discussion. Recent developments that address important synthetic challenges are presented and highlighted with hundreds of examples.
Chiral Recognition In Separation Methods
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Author : Alain Berthod
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-06-16
Chiral Recognition In Separation Methods written by Alain Berthod and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-16 with Science categories.
What drives a scientist to edit a book on a speci c scienti c subject such as chiral mechanisms in separation methods? Until December 2005, the journal Analytical Chemistry of the American Chemical Society (Washington, DC) had an A-page section that was dedicated to simple and clear presentations of the most recent te- niques or the state of the art in a particular eld or topic. The “A-page” section was prepared for a broad audience of chemists including industrial professionals, s- dents as well as academics looking for information outside their eld of expertise. 1 Daniel W. Armstrong, one of the editors of this journal and a twenty-year+ long friend, invited me to present my view on chiral recognition mechanisms in a simple and clear way in an “A-page” article. In 2006, the “A-page” section was maintained as the rst articles at the beginning of each rst bi-monthly issue but the pagination was no longer page distinguished from the regular research articles published by the journal. During the time between the invitation and the submission, the A-page section was integrated into the rest of the journal and the article appeared as (2006) Anal Chem (78):2093–2099.
Chiral Separations By Liquid Chromatography
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Author :
language : en
Publisher:
Release Date : 1991
Chiral Separations By Liquid Chromatography written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Enantiomers categories.
Drug Stereochemistry
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Author : Irving Wainer
language : en
Publisher: CRC Press
Release Date : 1993-02-24
Drug Stereochemistry written by Irving Wainer and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-02-24 with Science categories.
Maintaining and enhancing its focus on key issues in the development, regulatory approval and use of stereoisomeric compounds, this edition continues to cover in detail all aspects of chiral drugs from the academic, governmental, industrial and clinical points of view.;Completely rewritten and updated throughout, Drug Stereochemistry: illustrates current indirect chromatographic methods for the resolution of drug enantiomers; treats the rapidly growing area of enantioselective gas chromatography; discusses the latest in HPLC resolution of enantiomeric drugs; uses verapamil as a model to show how stereoselective pharmacokinetics affect pharmacodynamics; and supplies an in-depth study on the effect of stereoselective plasma protein binding.;This edition offers entirely new chapters that: discuss the recent decisions and present position of the US Food and Drug Administration on the development of stereoisomeric drugs; explicate enzymatic synthesis of stereochemically pure drugs; review the toxicological, pharmacokinetic and pharmacodynamic differences found among stereoisomers; elucidate the stereoselective transport of drugs across epithelia; and give a physician's perspective on the questions and problems caused by stereoisomeric drugs in practice as well as the pharmaceutical industry's collective viewpoint based on a national survey.