Clinical Applications Of Continuous Infusion Chemotherapy And Concomitant Radiation Therapy
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Clinical Applications Of Continuous Infusion Chemotherapy And Concomitant Radiation Therapy
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Author : C. Julian Rosenthal
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Clinical Applications Of Continuous Infusion Chemotherapy And Concomitant Radiation Therapy written by C. Julian Rosenthal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The first conference on concomitant infusion chemotherapy and radia tion therapy was organized with the intention of bringing together some of the investigators who have tested, during the last few years, the hypo thesis that continuous infusion chemotherapy could modulate the cytotoxic effect of radiation therapy to the point of having a strongly additive, if not synergistic activity on certain malignant tumors. This volume represents the detailed proceedings of this conference presented in a way that offers the reader a review of the on-going re search in the field. We have stressed a number of subjects from basic biologic research and influence of cell kinetics to the practical methods of drug delivery systems and early clinical experiences. The rationale for this new type of combined modality therapy has been presented by some of its pioneers. Early clinical investigations as well as the preliminary data of many that have not yet completely matured have also been included. The reader should look at these data with some reser vations. Ultimately, these results must be confirmed by larger prospective randomized studies with proper controls before becoming accepted as the treatment of choice in locally advanced tumors.
Concomitant Continuous Infusion Chemotherapy And Radiation
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Author : Marvin Rotman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Concomitant Continuous Infusion Chemotherapy And Radiation written by Marvin Rotman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The administration of chemotherapeutic agents by continuous infusion with concomitant radiation therapy heralds a new approach in the treatment of cancer. This comprehensive book on the subject includes, besides a discussion of its scientific basis, the most promising clinical data on the use of continuous infusion chemotherapy and radiation. Thus, it is an important update for clinical investigators involved in frontline research as well as for practicing physicians participating in the direct care of cancer patients. The contributions include the latest results of this new approach in a number of tumor sites. There is a detailed description of the principles of radiosensitization for malignant tumors and radioprotection for normal tissues; these are the principles which have led to concrete clinical applications. There is also a presentation of the most recent data on the beneficial effects resulting from the administration of commonly used drugs, such as 5-fluorouracil, cisplatinum and adriamycin, with concomitant radiation therapy. Much of the data has never before been published. The wealth of information in this volume makes it a valuable reference; at the same time it gives practicing physicians a detailed presentation of various therapeutic regimens which they could administer in their daily clinical practice. In the future, this innovative cancer treatment may lead to the decreased need for radical surgery and the increased ability to preserve organ function.
Antitumor Drug Radiation Interactions
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Author : Bridget T. Hill
language : en
Publisher: CRC Press
Release Date : 2018-01-10
Antitumor Drug Radiation Interactions written by Bridget T. Hill and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-10 with Medical categories.
This volume reviews the experimental data on drug-radiation interactions. Special emphasis is placed on clinically-useful antitumor drugs. Particular reference is made to appropriate timing, concentration and sequencing of drug-radiation combinations. It includes discussions on the relative merits of experimental data derived from animal versus human tumors. This book also presents a section on the potential for new model systems or alternative test procedures for evaluating therapeutic benefits and cytotoxicities. Results of randomized clinical studies are reviewed with emphasis on recent studies involving protocols specifically designed to test the benefits from optimal integration of chemotherapy with radiotherapy. This book is intended for laboratory researchers in the field and clinicians interested in using the combined modality approach. It is also a useful resource for radiologists, oncologists, and all those interested in cancer research.
Conference On The Interaction Of Radiation Therapy And Chemotherapy
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Author :
language : en
Publisher:
Release Date : 1988
Conference On The Interaction Of Radiation Therapy And Chemotherapy written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Cancer categories.
Chemotherapy Protocols And Infusion Sequence
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Author : Iago Dillion Lima Cavalcanti
language : en
Publisher: Springer Nature
Release Date : 2022-10-18
Chemotherapy Protocols And Infusion Sequence written by Iago Dillion Lima Cavalcanti and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-18 with Medical categories.
This book aims to address the infusion sequence of the main protocols used in the treatment of varied solid cancers. Since an inadequate infusion sequence can compromise the patient's treatment, this work will provide support to professionals working in the field of oncology in assessing each chemotherapy infusion sequence. The introductory chapters present the definition, indication, and the risks and benefits of polypharmacy in cancer therapy, and discuss the importance of drug combination in cancer treatment. Chapter 2 focuses on the challenges and also the toxicity of combination therapy in cancer, while chapter 3 highlights the parameters that must be evaluated before defining the infusion sequence, such as pharmacodynamic and pharmacokinetic profiles, drugs’ stability when diluted or reconstituted, toxicological profile of each drug, among others. The remaining chapters are divided by type of cancer. The content is focused on solid tumors, dividing the chapters according to breast, gastrointestinal, genitourinary, gynecological, head and neck, lung, and neurological cancers. In each chapter the epidemiological profiles, pathophysiology, therapeutic modalities, and the main chemotherapy protocols are addressed, as well as efficacy studies and data on the infusion sequence of each mentioned protocol. This work will be a valuable resource to physicians, nurses, and pharmacists, and may help to improve health service practices.
Breast Cancer An Issue Of Hematology Oncology Clinics Of North America
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Author : Harold J. Burstein
language : en
Publisher: Elsevier Health Sciences
Release Date : 2013-08-28
Breast Cancer An Issue Of Hematology Oncology Clinics Of North America written by Harold J. Burstein and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-28 with Medical categories.
This issue, focusing on Breast Cancer, includes topics such as: Radiation Therapy for DCIS, Axillary dissection, Pathology in the age of personalized breast cancer treatment:, Clinical implications for breast cancer subsets defined by molecular diagnostics, Management of CNS Metastases in Breast Cancer, Endocrine therapy for advanced breast cancer, Targeting the PI3K pathway in breast cancer, Treating the Older Breast Cancer Patient, Adjuvant chemotherapy in the age of targeted treatment, and Novel radiotherapy approaches for early breast cancer.
Chemoradiation In Cancer Therapy
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Author : Hak Choy
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-12-04
Chemoradiation In Cancer Therapy written by Hak Choy and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-12-04 with Medical categories.
Internationally recognized experts in cancer biology and clinical research review the present status of the multimodality approach to the management of solid tumors and speculate on possible future strategies for chemoradiation therapy. The authors detail applications of combined modality therapy in lung, esophageal, breast, gastric, pancreatic, colon, and rectal cancers. They also show how radiation interacts with such chemotherapeutic agents as the platinum complexes, taxanes, and gemcitabine in the treatment of malignant gliomas, and head and neck cancer. A review of how to integrate new specific molecular targeted agents into multimodality therapy in the future.
National Library Of Medicine Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date :
National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medicine categories.
Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date :
Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medicine categories.
First multi-year cumulation covers six years: 1965-70.
Nci Monographs
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Author :
language : en
Publisher:
Release Date : 1986
Nci Monographs written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Cancer categories.