Clinical Pharmacology In The Elderly
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Clinical Pharmacology In The Elderly
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Author : Hans-Peter Breuel
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Clinical Pharmacology In The Elderly written by Hans-Peter Breuel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The appropriate and rational use of drugs by the elderly is a matter of growing medical and social concern. Persons aged 65 years and older constitute about 12%-15% of the population in the Western world, and the total number of the elderly will increase significantly in the coming years. This population accounts for 30% of all the prescription drugs used. Aging, specifically the transition from middle to old age, is a complex process. From the perspective of clinical pharmacology, these pathophysiological changes may reasonably be expected to alter responsiveness to drugs. The age-related differences in response to drugs can arise from alterations in pharmacokinetics or pharmacodynamics. This makes it mandatory that clinical pharma cological studies be carried out in the elderly during extended phase I studies. The older the population likely to use the drug, the more important it is to include the very old. It is also important not to exclude .... :''lecessarily patients with concomitant illnesses; it is only by observing, such patients that drug-disease interactions can be detected. Reports from surveillance systems have greatly increased our awareness of problems associated with drug therapy in old age.
Drugs And The Elderly
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Author : J. Crooks
language : en
Publisher: Springer
Release Date : 1979-06-17
Drugs And The Elderly written by J. Crooks and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979-06-17 with Medical categories.
Clinical Pharmacology In The Elderly
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Author : Hans-Peter Breuel
language : en
Publisher: Springer
Release Date : 2014-03-12
Clinical Pharmacology In The Elderly written by Hans-Peter Breuel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-12 with Medical categories.
The appropriate and rational use of drugs by the elderly is a matter of growing medical and social concern. Persons aged 65 years and older constitute about 12%-15% of the population in the Western world, and the total number of the elderly will increase significantly in the coming years. This population accounts for 30% of all the prescription drugs used. Aging, specifically the transition from middle to old age, is a complex process. From the perspective of clinical pharmacology, these pathophysiological changes may reasonably be expected to alter responsiveness to drugs. The age-related differences in response to drugs can arise from alterations in pharmacokinetics or pharmacodynamics. This makes it mandatory that clinical pharma cological studies be carried out in the elderly during extended phase I studies. The older the population likely to use the drug, the more important it is to include the very old. It is also important not to exclude .... :''lecessarily patients with concomitant illnesses; it is only by observing, such patients that drug-disease interactions can be detected. Reports from surveillance systems have greatly increased our awareness of problems associated with drug therapy in old age.
Clinical Pharmacology In The Elderly
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Author : Cameron G. Swift
language : en
Publisher: CRC Press
Release Date : 1987-01-30
Clinical Pharmacology In The Elderly written by Cameron G. Swift and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-01-30 with Medical categories.
Drugs And The Elderly
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Author : James Crooks
language : en
Publisher:
Release Date : 1979
Drugs And The Elderly written by James Crooks and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Aging categories.
Pharmacokinetics And Drug Interactions In The Elderly And Special Issues In Elderly African American Populations
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 1997-08-25
Pharmacokinetics And Drug Interactions In The Elderly And Special Issues In Elderly African American Populations written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-08-25 with Medical categories.
Reports in the popular press about the increasing longevity of Americans and the aging of the baby boom generation are constant reminders that the American population is becoming older. Consequently, an issue of growing medical, health policy, and social concern is the appropriate and rational use of medications by the elderly. Although becoming older does not necessarily correlate with increasing illness, aging is associated with anatomical and physiological changes that affect how medications are metabolized by the body. Furthermore, aging is often related to an increased frequency of chronic illness (often combined with multiple health problems) and an increased use of medications. Thus, a better understanding of the absorption, distribution, metabolism, and excretion of drugs; of the physiologic responses to those medications; as well as of the interactions among multiple medications is crucial for improving the health of older people.
Clinical Pharmacology And Drug Treatment In The Elderly
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Author : Kevin O'Malley (MD.)
language : en
Publisher:
Release Date : 1984
Clinical Pharmacology And Drug Treatment In The Elderly written by Kevin O'Malley (MD.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Chemotherapy categories.
Prescribing For Elderly Patients
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Author : Stephen Jackson
language : en
Publisher: John Wiley & Sons
Release Date : 2009-04-22
Prescribing For Elderly Patients written by Stephen Jackson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-22 with Medical categories.
A guide for doctors to quickly choose the right drugs in the right dose for the most important clinical problems in the elderly Prescribing medications for elderly patients is complex - this book gives clear advice on treatment regimes, drug interactions, adverse effects, and recommended dose changes Provides practical help with the problems that can arise in reaching an accurate diagnosis in the elderly, recommends clear treatment options, lists key drug interactions and side effects, and advises when to amend doses
Drug Studies In The Elderly
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Author : N.R. Cutler
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Drug Studies In The Elderly written by N.R. Cutler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
Clinical trials are the most definitive tool for evaluation of the applica bility of clinical investigations. The main objective of clinical investiga tions is to assess the potential value of a therapeutic entity in the treat ment or prophylaxis of a disease or a condition. It is also deemed necessary at this stage to obtain information regarding the undesirable side effects, associated risks, and their interrelationship with clinical assessments. Most of these clinical investigations conform, in some form or fashion, to the guidelines adopted by the Food and Drug Administration (FDA) for a given class of compounds. Clinical investigations in the past have not included specific studies in special or subpopulations, e.g., the elderly. Because of an ever-increasing elderly population, newer policies for clinical investigations are now being debated with the recognition of enhanced drug sensitivity in this special population. This key research activity can lead not only to improved health care in the elderly but also to control of its costs.
Geriatric Clinical Pharmacology
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Author : W. Gibson Wood
language : en
Publisher:
Release Date : 1987-01-01
Geriatric Clinical Pharmacology written by W. Gibson Wood and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-01-01 with categories.