Clinical Trial Design Challenges In Mood Disorders
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Clinical Trial Design Challenges In Mood Disorders
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Author : Mauricio Tohen
language : en
Publisher: Academic Press
Release Date : 2015-01-24
Clinical Trial Design Challenges In Mood Disorders written by Mauricio Tohen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-24 with Medical categories.
Poor clinical trial designs result in failed studies wasting research funds and limiting the advancement of cures for disorders. Clinical Trial Design Challenges in Mood Disorders outlines classic problems researchers face in designing clinical trials and discusses how best to address them for the most definitive and generalizable results. Traditional trial designs are included as well as novel analytic techniques. The book examines information on high placebo response, the generalizability of studies conducted in the developing world, the duration of maintenance studies, and the application of findings into clinical practice. With representation from contributors throughout the world and from academia, industry, regulatory agencies, and advocacy groups, this book will contribute toward improved clinical trial design and valid, precise, and reliable answers about what works better and faster for patients. Summarizes common trial design problems and their solutions Encompasses funding, subject selection, regulatory issues and more Identifies best practices for definitive and generalizable results Includes traditional trial designs and novel analytic techniques Represents academia, industry, regulatory agencies, and advocacy groups
Clinical Trials In Psychiatry
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Author : Brian S. Everitt
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15
Clinical Trials In Psychiatry written by Brian S. Everitt and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.
At last – a new edition of the highly acclaimed book Clinical Trials in Psychiatry This book provides a concise but thorough overview of clinical trials in psychiatry, invaluable to those seeking solutions to numerous problems relating to design, methodology and analysis of such trials. Practical examples and applications are used to ground theory whenever possible. The Second Edition includes new information regarding: Recent important psychiatric trials More specific discussion of psychiatry in the USA and the particular problems of trials in the USA, including comments about the FDA (U.S. Food and Drug Administration) An extended chapter on meta-analysis Further discussion of sub-group analysis Special features include appendices outlining how to design and report clinical trials, what websites and software programs are appropriate and an extensive reference section. From the reviews of the First Edition: “Everitt & Wessely are to be congratulated on producing an excellent guide to help overcome the snags in clinical trial research. Clearly written and in an engrossing style, the book is likely to become a classic textbook on clinical trials, and not just in psychiatry. The authors’ enthusiasm and grasp of clinical trial research make for a gripping and insightful read...it is one of the very best books that has been written on clinical trials.” THE BRITISH JOURNAL OF PSYCHIATRY "The experience of both authors in this area gives the book a very pragmatic approach grounded in reality, with theoretical overviews invariably being followed by practical examples and applications... an invaluable companion to anyone involved in, or contemplating undertaking, clinical trials research.” PSYCHOLOGICAL MEDICINE
Behavioral Clinical Trials For Chronic Diseases
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Author : Lynda H. Powell
language : en
Publisher: Springer Nature
Release Date : 2021-10-13
Behavioral Clinical Trials For Chronic Diseases written by Lynda H. Powell and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-13 with Psychology categories.
This is the first comprehensive guide to the design of behavioral randomized clinical trials (RCT) for chronic diseases. It includes the scientific foundations for behavioral trial methods, problems that have been encountered in past behavioral trials, advances in design that have evolved, and promising trends and opportunities for the future. The value of this book lies in its potential to foster an ability to “speak the language of medicine” through the conduct of high-quality behavioral clinical trials that match the rigor commonly seen in double-blind drug trials. It is relevant for testing any treatment aimed at improving a behavioral, social, psychosocial, environmental, or policy-level risk factor for a chronic disease including, for example, obesity, sedentary behavior, adherence to treatment, psychosocial stress, food deserts, and fragmented care. Outcomes of interest are those that are of clinical significance in the treatment of chronic diseases, including standard risk factors such as cholesterol, blood pressure, and glucose, and clinical outcomes such as hospitalizations, functional limitations, excess morbidity, quality of life, and mortality. This link between behavior and chronic disease requires innovative clinical trial methods not only from the behavioral sciences but also from medicine, epidemiology, and biostatistics. This integration does not exist in any current book, or in any training program, in either the behavioral sciences or medicine.
The American Psychiatric Association Publishing Textbook Of Mood Disorders Second Edition
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Author : Charles B. Nemeroff, M.D., Ph.D.
language : en
Publisher: American Psychiatric Pub
Release Date : 2022-06-16
The American Psychiatric Association Publishing Textbook Of Mood Disorders Second Edition written by Charles B. Nemeroff, M.D., Ph.D. and has been published by American Psychiatric Pub this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-16 with Medical categories.
Preceded by: The American Psychiatric Publishing textbook of mood disorders / edited by Dan J. Stein, David J. Kupfer, Alan F. Schatzberg. 1st ed. c2006.
The Medical Basis Of Psychiatry
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Author : S. Hossein Fatemi
language : en
Publisher: Springer
Release Date : 2016-03-17
The Medical Basis Of Psychiatry written by S. Hossein Fatemi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-17 with Medical categories.
Four years have passed since the last edition (3rd) of this book was published. In the intervening years, several reviews of this book have provided highly encouraging remarks about the value of this book in transmitting information on classification and treatment of psychiatric disorders to the audience. We are proposing to revise all chapters with an eye on accuracy and ease of use, and this is an especially timely endeavor with the upcoming publication of the Diagnostic and Statistical Manual V. All the appropriate new information on biology, etiology, diagnosis and treatment of psychiatric disorders will be added to the current proposed edition. It is our goal to recruit the same authors (if possible) who contributed to the previous edition. While all chapters will be updated (see TOC), those marked by asterisks will be the most likely to undergo more revision. Psychiatry has emerged as a burgeoning scientific field with major advances in etiology and treatment of several disorders. Just as there was excitement in the anatomic advances that took place a hundred years ago when Emil Kraepelin and his collaborators took on the enormous task of classification of psychiatric disorders based on rational scientific thinking, new advances in genetics, biochemistry, neuroanatomy and pharmacotherapy of mental disorders have brought us even closer to a better understanding of complex disorders like schizophrenia, bipolar disorder, depression and even autism. The major goal of the previous edition of this classic book was to update the busy clinician, psychiatric resident and medical student with the most up-to-date information on etiology, diagnosis and treatment of psychiatric disorders. This goal remains the focus of the fourth edition of this book. In this updated and expanded edition, the reader will be provided with the most contemporary information and literature supported by a close survey of the field. This new edition of this classic title, with its focus on biologic and medical aspects of psychiatry, will continue to be of significant help to all interested in the scientific practice of psychiatry.
Understanding Research For Nursing Students
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Author : Peter Ellis
language : en
Publisher: SAGE
Release Date : 2022-04-08
Understanding Research For Nursing Students written by Peter Ellis and has been published by SAGE this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-08 with Medical categories.
This bestselling introduction to research supports nursing students by demystifying jargon, explaining the key concepts and building their skills in applying research principles to their studies and practice.
Mood Disorders
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Author : Eric J. L. Griez
language : en
Publisher: Wiley
Release Date : 2005-03-04
Mood Disorders written by Eric J. L. Griez and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-03-04 with Medical categories.
Written by an outstanding team of internationally recognised experts, this practical textbook is based on the European Certificate in Anxiety and Mood Disorders. It provides a thorough overview of diagnosis and treatment of mood disorders and analyses the most recent developments and scientific evidence. Covers the most important clinical topics in the field, including symptomatology, natural course and diagnosis Treatment strategies are reviewed in the light of all available empirical evidence Outstanding list of international contributors
Healthy Aging
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Author : Patrick P. Coll
language : en
Publisher: Springer
Release Date : 2019-03-29
Healthy Aging written by Patrick P. Coll and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-29 with Medical categories.
This book weaves all of these factors together to engage in and promote medical, biomedical and psychosocial interventions, including lifestyle changes, for healthier aging outcomes. The text begins with an introduction to age-related changes that increase in disease and disability commonly associated with old age. Written by experts in healthy aging, the text approaches the principles of disease and disability prevention via specific health issues. Each chapter highlights the challenge of not just increasing life expectancy but also deceasing disease burden and disability in old age. The text then shifts into the whole-person implications for clinicians working with older patients, including the social and cultural considerations that are necessary for improved outcomes as Baby Boomers age and healthcare systems worldwide adjust. Healthy Aging is an important resource for those working with older patients, including geriatricians, family medicine physicians, nurses, gerontologists, students, public health administrators, and all other medical professionals.
The Ethical Challenges Of Emerging Medical Technologies
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Author : Arthur L. Caplan
language : en
Publisher: Routledge
Release Date : 2020-09-10
The Ethical Challenges Of Emerging Medical Technologies written by Arthur L. Caplan and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-10 with Health & Fitness categories.
This collection of essays emphasizes society’s increasingly responsible engagement with ethical challenges in emerging medical technology. Expansion of technological capacity and attention to patient safety have long been integral to improving healthcare delivery but only relatively recently have concepts like respect, distributive justice, privacy, and autonomy gained some power to shape the development, use, and refinement of medical tools and techniques. Medical ethics goes beyond making better medicine to thinking about how to make the field of medicine better. These essays showcase several ways in which modern ethical thinking is improving safety, efficacy and efficiency of medical technology, increasing access to medical care, and empowering patients to choose care that comports with their desires and beliefs. Included are complimentary ethical approaches as well as compelling counter-arguments. Together, the articles demonstrate how improving the quality of medical technology relies on every stakeholder -- not just medical researchers and scientists -- to assess each given technology’s strengths and pitfalls. This collection also portends one of the next major issues in the ethics of medical technology: developing the requisite moral framework to accompany shifts toward patient-centred personalized healthcare.
Clinical Trials In Older Adults
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Author : Antonio Cherubini
language : en
Publisher: John Wiley & Sons
Release Date : 2016-01-13
Clinical Trials In Older Adults written by Antonio Cherubini and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-13 with Medical categories.
Clinical Trials in Older Adults is the first book to consider the methodological issues underlying the evaluation of new treatments in older people. Provides information on the methodology, monitoring and regulations for those planning to conduct a clinical trials involving older adults Contains examples of ongoing trials involving older adults, and presents the main characteristics of many recently published Depicts how the issues regarding older adults in clinical trials could be properly addressed with the appropriate study design and conduct Identifies key issues in performing clinical trials in older patients with common geriatric conditions, i.e. Alzheimer’s dementia, depression, low muscle mass, cancer