Community Series In Novel Biomarkers For Predicting Response To Cancer Immunotherapy Volume Ii
DOWNLOAD
Download Community Series In Novel Biomarkers For Predicting Response To Cancer Immunotherapy Volume Ii PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Community Series In Novel Biomarkers For Predicting Response To Cancer Immunotherapy Volume Ii book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Community Series In Novel Biomarkers For Predicting Response To Cancer Immunotherapy Volume Ii
DOWNLOAD
Author :
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-10
Community Series In Novel Biomarkers For Predicting Response To Cancer Immunotherapy Volume Ii written by and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-10 with Medical categories.
This Research Topic is the second volume of the “Community Series in Novel Biomarkers for Predicting Response to Cancer Immunotherapy". Please see Volume I here. Immunotherapy has revolutionized the treatment of malignancies. Targeting of immune checkpoints cytotoxic T-lymphocyte-associated protein 4, programmed cell death protein 1 (PD-1) and its ligand (PD-L1) has led to improving survival in a subset of patients. Despite their remarkable success, clinical benefit remains limited to only a subset of patients. A significant limitation behind these current treatment modalities is an irregularity in clinical response, which is especially pronounced among checkpoint inhibition. Currently, relevant predictors of cancer immunotherapy response include microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR), expression of PD-L1, tumor mutation burden (TMB), immune genomic characteristics, and tumor infiltrating lymphocytes (TILs). However, none of them have sufficient evidence to be a stratification factor. Moreover, as the combined strategies for effective cancer immunotherapy had been developed in multiple tumors, such as Immunotherapy combined with chemotherapy, radiotherapy, targeted therapy and anti-angiogenesis therapy. Therefore, the development of novel biomarkers endowed with high sensitivity, specificity and accuracy able to identify which patients may truly benefit from the treatment with cancer immunotherapy would allow to refine the therapeutic selection and to better tailor the treatment strategy. This research topic aims to focus on the advances in the discoveries of novel biomarkers for predicting response to cancer immunotherapy in various tumors. We welcome the submission of original research and review articles that include biomarkers in clinical study and applications, as well as technologies or discoveries in experimental approaches.
Novel Biomarkers For Predicting Response To Cancer Immunotherapy
DOWNLOAD
Author : Jinghua Pan
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-11
Novel Biomarkers For Predicting Response To Cancer Immunotherapy written by Jinghua Pan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-11 with Medical categories.
Immunotherapy has revolutionized the treatment of malignancies. Targeting of immune checkpoints cytotoxic T-lymphocyte-associated protein 4, programmed cell death protein 1 (PD-1) and its ligand (PD-L1) has led to improving survival in a subset of patients. Despite their remarkable success, clinical benefit remains limited to only a subset of patients. A significant limitation behind these current treatment modalities is an irregularity in clinical response, which is especially pronounced among checkpoint inhibition. Currently, relevant predictors of cancer immunotherapy response include microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR), expression of PD-L1, tumor mutation burden (TMB), immune genomic characteristics, and tumor infiltrating lymphocytes (TILs). However, none of them have sufficient evidence to be a stratification factor. Moreover, as the combined strategies for effective cancer immunotherapy had been developed in multiple tumors, such as Immunotherapy combined with chemotherapy, radiotherapy, targeted therapy and anti-angiogenesis therapy. Therefore, the development of novel biomarkers endowed with high sensitivity, specificity and accuracy able to identify which patients may truly benefit from the treatment with cancer immunotherapy would allow to refine the therapeutic selection and to better tailor the treatment strategy.
Community Series In Immunotherapy With Checkpoint Inhibitors For Non Small Cell Lung Cancer Colon Cancer And Esophageal Cancer Volume Ii
DOWNLOAD
Author : Xuelei Ma
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-27
Community Series In Immunotherapy With Checkpoint Inhibitors For Non Small Cell Lung Cancer Colon Cancer And Esophageal Cancer Volume Ii written by Xuelei Ma and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-27 with Medical categories.
Community Series In Post Translational Modifications Of Proteins In Cancer Immunity And Immunotherapy Volume Ii
DOWNLOAD
Author : Xiangpeng Dai
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-25
Community Series In Post Translational Modifications Of Proteins In Cancer Immunity And Immunotherapy Volume Ii written by Xiangpeng Dai and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-25 with Medical categories.
Community Series In Novel Insights Into Immunotherapy Targeting Tumor Microenvironment In Ovarian Cancer Volume I
DOWNLOAD
Author : Xiao Liang
language : en
Publisher: Frontiers Media SA
Release Date :
Community Series In Novel Insights Into Immunotherapy Targeting Tumor Microenvironment In Ovarian Cancer Volume I written by Xiao Liang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.
Community Series In Combining Chemo Radio Therapy And Immunotherapy For Cancers Perfect Mix Of Old And New Volume Ii
DOWNLOAD
Author : Jian Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-23
Community Series In Combining Chemo Radio Therapy And Immunotherapy For Cancers Perfect Mix Of Old And New Volume Ii written by Jian Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-23 with Medical categories.
Community Series In Manipulating The Immunological Tumor Microenvironment Volume Ii
DOWNLOAD
Author : Huanfa Yi
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-17
Community Series In Manipulating The Immunological Tumor Microenvironment Volume Ii written by Huanfa Yi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-17 with Medical categories.
Community Series In The Role Of Angiogenesis And Immune Response In Tumor Microenvironment Of Solid Tumor Volume Ii
DOWNLOAD
Author : Xi Cheng
language : en
Publisher: Frontiers Media SA
Release Date : 2023-12-13
Community Series In The Role Of Angiogenesis And Immune Response In Tumor Microenvironment Of Solid Tumor Volume Ii written by Xi Cheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-13 with Medical categories.
This Research Topic is the second volume of the “Community Series in the Role of Angiogenesis and Immune Response in Tumor Microenvironment of Solid Tumor". Please Volume I here. The microenvironment of tumors is consisted of the tumor stroma, proliferating tumor cells, infiltrating inflammatory cells, blood vessels, and various associated tissue cells. The pre-metastatic niche (PRN) is described as supportive and receptive, which undergoes cellular and molecular changes to form the fertile “soil” or metastatic-designated sites for metastatic tumor cell “seed” colonization. Thus, the PRN supports promoting tumor metastasis and tumor settlement in distant organs. The infiltration of the immune cells and the formation of blood vessels from the pre-metastatic sites are critical for the tumor microenvironment. Typically, the angiogenic factor is strongly associated with the inflammatory response during the development of tumors. Additionally, the immunoediting processes are essentially devoted to promoting angiogenesis and modulating the innate and specific immune responses.
Community Series In Unveiling The Tumor Microenvironment By Machine Learning To Develop New Immunotherapeutic Strategies Volume Ii
DOWNLOAD
Author : Ping Zheng
language : en
Publisher: Frontiers Media SA
Release Date : 2024-02-06
Community Series In Unveiling The Tumor Microenvironment By Machine Learning To Develop New Immunotherapeutic Strategies Volume Ii written by Ping Zheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-06 with Medical categories.
Community Series In Neurobiological Biomarkers For Developing Novel Treatments Of Substance And Non Substance Addiction Volume Ii
DOWNLOAD
Author : Yanhui Liao
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-17
Community Series In Neurobiological Biomarkers For Developing Novel Treatments Of Substance And Non Substance Addiction Volume Ii written by Yanhui Liao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-17 with Medical categories.
This Research Topic is the second volume of the 'Community Series in Neurobiological Biomarkers for Developing Novel Treatments of Substance and Non-Substance Addiction'. Please see the first volume here. Many people suffer from substance (from nicotine or alcohol to heroin, methamphetamine, cocaine, etc) or non-substance (from gaming/gambling to shopping, internet, smartphone, etc) addiction. Both types of addiction are associated with severe health, economic and social consequences and are far too often result in both familial and personal tragedies. Unfortunately, current treatments are not very effective for either substance or non-substance addiction so novel treatments are desperately needed. For example, for nicotine addiction, despite very well-documented health risks of cigarette smoking and its economic and societal costs, globally, more than 30% of males still smoke, and although many smokers desire to quit, only approximately 5-30% will achieve abstinence with 6 months or more of the best available current treatments. And the story for nicotine addiction is far from unique, presenting a huge challenge for the entire addiction field. Therefore, there is a vital need to improve outcomes for the treatment of both substance and non-substance addictions. Recent work exploring neurobiological mechanisms of the treatment response at the molecular, cellular and systems levels with a broad range of technologies, such as Magnetic Resonance Imaging (MRI), genetics and genomics, have opened new avenues for developing novel treatments through the detection of neurobiological biomarkers predicting efficacious outcomes in addicted patients.