Community Series In The Role Of Angiogenesis And Immune Response In Tumor Microenvironment Of Solid Tumor Volume Ii

DOWNLOAD

Download Community Series In The Role Of Angiogenesis And Immune Response In Tumor Microenvironment Of Solid Tumor Volume Ii PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Community Series In The Role Of Angiogenesis And Immune Response In Tumor Microenvironment Of Solid Tumor Volume Ii book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page

Community Series In The Role Of Angiogenesis And Immune Response In Tumor Microenvironment Of Solid Tumor Volume Ii

DOWNLOAD
Author : Xi Cheng
language : en
Publisher: Frontiers Media SA
Release Date : 2023-12-13

Community Series In The Role Of Angiogenesis And Immune Response In Tumor Microenvironment Of Solid Tumor Volume Ii written by Xi Cheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-13 with Medical categories.

This Research Topic is the second volume of the “Community Series in the Role of Angiogenesis and Immune Response in Tumor Microenvironment of Solid Tumor". Please Volume I here. The microenvironment of tumors is consisted of the tumor stroma, proliferating tumor cells, infiltrating inflammatory cells, blood vessels, and various associated tissue cells. The pre-metastatic niche (PRN) is described as supportive and receptive, which undergoes cellular and molecular changes to form the fertile “soil” or metastatic-designated sites for metastatic tumor cell “seed” colonization. Thus, the PRN supports promoting tumor metastasis and tumor settlement in distant organs. The infiltration of the immune cells and the formation of blood vessels from the pre-metastatic sites are critical for the tumor microenvironment. Typically, the angiogenic factor is strongly associated with the inflammatory response during the development of tumors. Additionally, the immunoediting processes are essentially devoted to promoting angiogenesis and modulating the innate and specific immune responses.

Community Series In Manipulating The Immunological Tumor Microenvironment Volume Ii

DOWNLOAD
Author : Huanfa Yi
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-17

Community Series In Manipulating The Immunological Tumor Microenvironment Volume Ii written by Huanfa Yi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-17 with Medical categories.

Community Series In Novel Insights Into Immunotherapy Targeting Tumor Microenvironment In Ovarian Cancer Volume I

DOWNLOAD
Author : Xiao Liang
language : en
Publisher: Frontiers Media SA
Release Date :

Community Series In Novel Insights Into Immunotherapy Targeting Tumor Microenvironment In Ovarian Cancer Volume I written by Xiao Liang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.

The Role Of Angiogenesis And Immune Response In Tumor Microenvironment Of Solid Tumor

DOWNLOAD
Author : Ren Zhao
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-11

The Role Of Angiogenesis And Immune Response In Tumor Microenvironment Of Solid Tumor written by Ren Zhao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-11 with Medical categories.

Community Series In The Role Of Cd1 And Mr1 Restricted T Cells In Immunity And Disease Volume Ii

DOWNLOAD
Author : Luc Van Kaer
language : en
Publisher: Frontiers Media SA
Release Date : 2024-09-26

Community Series In The Role Of Cd1 And Mr1 Restricted T Cells In Immunity And Disease Volume Ii written by Luc Van Kaer and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-26 with Medical categories.

This is the second volume in the series, the Role of CD1- and MR1-restricted T cells in Immunity and Disease. Please see volume I here. CD1 and MR1 are major histocompatibility complex (MHC) class I-related proteins that bind and present non-peptide antigens to subsets of T cells with specialized functions. CD1 proteins typically present lipid antigens to CD1-restricted T cells, whereas MR1 presents vitamin B-based ligands and a variety of drugs and drug-like molecules to MR1-restricted T cells. The CD1 family of antigen-presenting molecules has been divided into two groups: Group 1 contains CD1a, CD1b, and CD1c, and Group 2 contains CD1d. Additionally, CD1e is expressed intracellularly and is involved in the loading of lipid antigens onto Group 1 CD1 proteins. Humans express both Groups 1 and 2 CD1 proteins, whereas mice only express CD1d. Group 1 CD1 proteins present lipid antigens to T cells that generally express diverse T cell receptors (TCRs) and exhibit adaptive-like functions, whereas CD1d presents lipid antigens to subsets of T cells that express either diverse or highly restricted TCRs and exhibit innate-like functions. CD1d-restricted T cells are called natural killer T (NKT) cells, which include Type I or invariant NKT (iNKT) cells expressing semi-invariant TCRs, and Type II NKT cells expressing more diverse TCRs. CD1-restricted T cells have been implicated in a wide variety of diseases, including cancer, infections, and autoimmune, inflammatory, and metabolic diseases. Additionally, NKT cells have been targeted for immunotherapy of disease with ligands such as ‎α or α-galactosylceramide for iNKT cells, or sulfatide for Type II NKT cells.

Community Series In Unveiling The Tumor Microenvironment By Machine Learning To Develop New Immunotherapeutic Strategies Volume Ii

DOWNLOAD
Author : Ping Zheng
language : en
Publisher: Frontiers Media SA
Release Date : 2024-02-06

Community Series In Unveiling The Tumor Microenvironment By Machine Learning To Develop New Immunotherapeutic Strategies Volume Ii written by Ping Zheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-06 with Medical categories.

Community Series In Novel Biomarkers In Tumor Immunity And Immunotherapy Volume Ii

DOWNLOAD
Author : Eyad Elkord
language : en
Publisher: Frontiers Media SA
Release Date : 2025-05-15

Community Series In Novel Biomarkers In Tumor Immunity And Immunotherapy Volume Ii written by Eyad Elkord and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-15 with Medical categories.

This Research Topic is the second volume of the “Novel Biomarkers in Tumor Immunity and Immunotherapy” Community Series. Please see Volume I here. Immune checkpoint inhibitors (ICIs) such as anti-PD-1 and anti-PD-L1 antibodies are highly effective against many types of cancer, yet durable responses are limited to a subset of patients highlighting the need for the development of effective biomarkers to predict prognosis and efficacy. Currently, PD-L1 expression in tumors, microsatellite instability (MSI) or mismatch repair deficiency (dMMR), and tumor mutation burden (TMB) are known as biomarkers for cancer immunotherapy but are not sufficient. Combination therapy with immune checkpoint inhibitors and chemotherapy or radiation therapy, as well as diverse therapies targeting intra-tumoral regulatory T cells have been described, but there are currently no unifying biomarkers that are applicable to clinically, a simple, fast, non-invasive method that can yield biomarkers of disease with a minimal adverse effect on patients is desirable. Recent findings suggest that the balancing of effector T cells and regulatory cells in the tumor microenvironment is associated with cancer progression and prognosis. Cells and molecules involved in the control of cancer are complex, and a better understanding of the tumor immune environment will lead to the development of truly effective biomarkers. This research topic will focus on novel biomarkers that predict efficacy, prognosis, or the development of adverse events in various cancer immunotherapies, and extensive basic research leading to the development of biomarkers. We expect a wide range of research, not only in serology, genetics, and immunocytochemistry but also in bacterial flora. Research on the development of novel assays and bioinformatics methods is also welcome: • Non-invasive biomarkers for cancer immunotherapy. • Bulk RNA-seq, scRNA-seq, or Rep-seq methods. • Correlation of tumor immune cells with gut microbiota in tumor immunotherapy. • Impact of Teff and Treg balance in the tumor microenvironment on tumor prognosis. • Inflammatory and immune signatures associated with drug response versus resistance in cancer. Please note that Topic Editor Dr. Takaji Matsutani is employed by Maruho Co., Ltd. The other Topic Editors declare no competing interests with regard to the Research Topic subject. Please also note that manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by robust and relevant validation (clinical cohort or biological validation in vitro or in vivo) are out of scope for this topic.

Community Series In Identification Function And Mechanisms Of Interferon Induced Genes Associated With Viruses Volume Ii

DOWNLOAD
Author : Chang Li
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-13

Community Series In Identification Function And Mechanisms Of Interferon Induced Genes Associated With Viruses Volume Ii written by Chang Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-13 with Medical categories.

Community Series In Novel Biomarkers For Predicting Response To Cancer Immunotherapy Volume Ii

DOWNLOAD
Author :
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-10

Community Series In Novel Biomarkers For Predicting Response To Cancer Immunotherapy Volume Ii written by and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-10 with Medical categories.

This Research Topic is the second volume of the “Community Series in Novel Biomarkers for Predicting Response to Cancer Immunotherapy". Please see Volume I here. Immunotherapy has revolutionized the treatment of malignancies. Targeting of immune checkpoints cytotoxic T-lymphocyte-associated protein 4, programmed cell death protein 1 (PD-1) and its ligand (PD-L1) has led to improving survival in a subset of patients. Despite their remarkable success, clinical benefit remains limited to only a subset of patients. A significant limitation behind these current treatment modalities is an irregularity in clinical response, which is especially pronounced among checkpoint inhibition. Currently, relevant predictors of cancer immunotherapy response include microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR), expression of PD-L1, tumor mutation burden (TMB), immune genomic characteristics, and tumor infiltrating lymphocytes (TILs). However, none of them have sufficient evidence to be a stratification factor. Moreover, as the combined strategies for effective cancer immunotherapy had been developed in multiple tumors, such as Immunotherapy combined with chemotherapy, radiotherapy, targeted therapy and anti-angiogenesis therapy. Therefore, the development of novel biomarkers endowed with high sensitivity, specificity and accuracy able to identify which patients may truly benefit from the treatment with cancer immunotherapy would allow to refine the therapeutic selection and to better tailor the treatment strategy. This research topic aims to focus on the advances in the discoveries of novel biomarkers for predicting response to cancer immunotherapy in various tumors. We welcome the submission of original research and review articles that include biomarkers in clinical study and applications, as well as technologies or discoveries in experimental approaches.

Community Series In Combining Chemo Radio Therapy And Immunotherapy For Cancers Perfect Mix Of Old And New Volume Ii

DOWNLOAD
Author : Jian Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-23

Community Series In Combining Chemo Radio Therapy And Immunotherapy For Cancers Perfect Mix Of Old And New Volume Ii written by Jian Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-23 with Medical categories.