Comparative Maternal And Epidemiologic Aspects
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Comparative Maternal And Epidemiologic Aspects
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Author : James Wilson
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Comparative Maternal And Epidemiologic Aspects written by James Wilson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
Modification of embryonic development by genetic differences in the mother is a well-regcognized phemomenon, but little is known about the genet ics of these maternal traits or the mechanisms by which they act. To illustrate the genetic approach to the problem, examples are given of how differences in embryonic response to a teratogen can be partitioned into those resulting from differences in embryonic genotype (including the possible role of X-linked genes in producing reciprocal cross differences), maternal genotype, and cytoplasmically transmitted factors. The advantages and limitations of analysis by appropriate crosses, in utero treatments, embryo transfers, and in vitro experiments are illustrated. The numerous inbred strains of the mouse, with well-documented physiology, the recently developed recombinant inbred strains, and the existence of easily identified biochemical marker genes offer at tractive opportunities, so far largely unexploited, for causal analysis of mater nal effects on teratological responses. VII. ADDENDUM Since this chapter was written, several relevant papers have appeared. The strain difference between AI] and C57BU6] mice in frequency of cleft-palate response to cortisone was fitted to a model of normally distributed log tolerance (Biddle and Fraser, 1976). Genetic differences, both in maternal uterine environment and embryonic response, can be represented in terms of their effect on the median effective dose required for the cleft-palate re sponse. The maternal effect of AI] dams relative to C57BU6] dams caused a two-fold reduction in embryonic tolerance to cortisone-induced cleft palate.
Comparative Maternal And Epidemiologic Aspects
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Author : James Wilson
language : en
Publisher:
Release Date : 2014-01-15
Comparative Maternal And Epidemiologic Aspects written by James Wilson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with categories.
Comparative Maternal And Epidemiologic Aspects
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Author : James Wilson
language : en
Publisher: Springer
Release Date : 1977-12-01
Comparative Maternal And Epidemiologic Aspects written by James Wilson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977-12-01 with Science categories.
Modification of embryonic development by genetic differences in the mother is a well-regcognized phemomenon, but little is known about the genet ics of these maternal traits or the mechanisms by which they act. To illustrate the genetic approach to the problem, examples are given of how differences in embryonic response to a teratogen can be partitioned into those resulting from differences in embryonic genotype (including the possible role of X-linked genes in producing reciprocal cross differences), maternal genotype, and cytoplasmically transmitted factors. The advantages and limitations of analysis by appropriate crosses, in utero treatments, embryo transfers, and in vitro experiments are illustrated. The numerous inbred strains of the mouse, with well-documented physiology, the recently developed recombinant inbred strains, and the existence of easily identified biochemical marker genes offer at tractive opportunities, so far largely unexploited, for causal analysis of mater nal effects on teratological responses. VII. ADDENDUM Since this chapter was written, several relevant papers have appeared. The strain difference between AI] and C57BU6] mice in frequency of cleft-palate response to cortisone was fitted to a model of normally distributed log tolerance (Biddle and Fraser, 1976). Genetic differences, both in maternal uterine environment and embryonic response, can be represented in terms of their effect on the median effective dose required for the cleft-palate re sponse. The maternal effect of AI] dams relative to C57BU6] dams caused a two-fold reduction in embryonic tolerance to cortisone-induced cleft palate.
Handbook Of Teratology
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Author : James Graves Wilson
language : en
Publisher:
Release Date : 1977
Handbook Of Teratology written by James Graves Wilson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with categories.
Reproductive And Perinatal Epidemiology
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Author : Michele Kiely
language : en
Publisher: CRC Press
Release Date : 2019-06-04
Reproductive And Perinatal Epidemiology written by Michele Kiely and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-04 with Medical categories.
First Published in 1990, Reproductive and Perinatal Epidemiology reviews topics that are central to reproductive and perinatal epidemiology, as well as the methodological issues surrounding research in maternal and child health. Important topics covered include prenatal care, Sudden Infant Death Syndrome (SIDS), epidemiology of neonatal brain hemorrhage, early pregnancy, methodological issues in drug epidemiology, environmental exposures and reproduction, and occupational exposures and reproduction. This book is essential reading for clinicians, researchers, obstetricians, pediatricians, and graduate students in public health.
Research Procedures And Data Analysis
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Author : James Wilson
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Research Procedures And Data Analysis written by James Wilson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
Handbook Of Behavioral Teratology
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Author : E.P. Riley
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Handbook Of Behavioral Teratology written by E.P. Riley and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Psychology categories.
This book was developed in response to a need in behavioral teratology for a comprehen sive set of reviews of the field's many topics brought together in a single source. This volume represents the first effort to synthesize and integrate research in the field since 1969 when Justin Joffe wrote Prenatal Determinants of Behaviour. Joffe's book became a standard reference for many years, particularly for the experimental design of animal investigations. It has become increasingly evident, however, that some aspects of design once considered inviolate have changed and become part of a more flexible approach. In current research the emphasis is on a set of prioritized, but focused, experimental ques tions rather than on designs which factor all possible variables into every experiment. Also, new design considerations have arisen over the last 15 years, not appreciated when Joffe wrote. Moreover, the sheer volume of new experimental evidence generated since 1969 has increased the content of the field several fold. These considerations made a new review and critical appraisal of the field compelling. The book is divided into four major sections. Part I contains four chapters. These chapters provide discussions of the general principles of behavioral teratogenesis, and information on the historical, governmental, and methodological contexts in which the field operates. The purpose of these chapters is to provide the framework within which the review chapters in the remainder of the book may best be understood.
Chemical Hazards To Human Reproduction
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Author :
language : en
Publisher:
Release Date : 1981
Chemical Hazards To Human Reproduction written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Chemicals categories.
Information Resources In Toxicology
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Author : Philip Wexler
language : en
Publisher: Academic Press
Release Date : 2000
Information Resources In Toxicology written by Philip Wexler and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.
History: -- K.D. Watson, P. Wexler, and J. Everitt. -- Highlights in the History of Toxicology. -- Selected References in the History of Toxicology. -- A Historical Perspective of Toxicology Information Systems. -- Books and Special Documents: -- G.L. Kennedy, Jr., P. Wexler, N.S. Selzer, and L.A. Malley. -- General Texts. -- Analytical Toxicology. -- Animals in Research. -- Biomonitoring/Biomarkers. -- Biotechnology. -- Biotoxins. -- Cancer. -- Chemical Compendia. -- Chemical--Cosmetics and Other Consumer. -- Products. -- Chemical--Drugs. -- Chemical--Dust and Fibers. -- Chemical--Metals. -- Chemicals--Pesticides -- Chemicals--Solvents. -- Chemical--Selected Chemicals. -- Clinical Toxicology. -- Developmental and Reproductive Toxicology. -- Environmental Toxicology--General. -- Environmental Toxicology-- Aquatic. -- Environmental Toxicology--Atmospheric. -- Environmental Toxicology--Hazardous Waste. -- Environmental Toxicology--Terrestrial. -- Environmental Toxicology--Wildlife. -- Ep ...
Expectations Of Life
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Author : H.O. Lancaster
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Expectations Of Life written by H.O. Lancaster and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Social Science categories.
Destined to become a classic epidemiological study, EXPECTA- TIONS OF LIFE surveys world mortality, describing and ex- plaining the declines of mortality which have become especi- ally evident in this century.