Handbook Of Teratology
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Handbook Of Teratology
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Author : F. Clarke Fraser
language : en
Publisher:
Release Date : 1977
Handbook Of Teratology written by F. Clarke Fraser and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with categories.
Handbook Of Teratology
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Author : James G. Wilson
language : en
Publisher:
Release Date : 1979
Handbook Of Teratology written by James G. Wilson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with categories.
Mechanisms And Pathogenesis
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Author : James Wilson
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Mechanisms And Pathogenesis written by James Wilson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
Handbook Of Teratology
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Author : James Graves Wilson
language : en
Publisher:
Release Date : 1977
Handbook Of Teratology written by James Graves Wilson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with categories.
Research Procedures And Data Analysis
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Author : James Wilson
language : en
Publisher: Springer
Release Date : 1978-07-01
Research Procedures And Data Analysis written by James Wilson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978-07-01 with Science categories.
Handbook Of Behavioral Teratology
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Author : E.P. Riley
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Handbook Of Behavioral Teratology written by E.P. Riley and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Psychology categories.
This book was developed in response to a need in behavioral teratology for a comprehen sive set of reviews of the field's many topics brought together in a single source. This volume represents the first effort to synthesize and integrate research in the field since 1969 when Justin Joffe wrote Prenatal Determinants of Behaviour. Joffe's book became a standard reference for many years, particularly for the experimental design of animal investigations. It has become increasingly evident, however, that some aspects of design once considered inviolate have changed and become part of a more flexible approach. In current research the emphasis is on a set of prioritized, but focused, experimental ques tions rather than on designs which factor all possible variables into every experiment. Also, new design considerations have arisen over the last 15 years, not appreciated when Joffe wrote. Moreover, the sheer volume of new experimental evidence generated since 1969 has increased the content of the field several fold. These considerations made a new review and critical appraisal of the field compelling. The book is divided into four major sections. Part I contains four chapters. These chapters provide discussions of the general principles of behavioral teratogenesis, and information on the historical, governmental, and methodological contexts in which the field operates. The purpose of these chapters is to provide the framework within which the review chapters in the remainder of the book may best be understood.
Comparative Maternal And Epidemiologic Aspects
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Author : James Wilson
language : en
Publisher: Springer
Release Date : 1977-12-01
Comparative Maternal And Epidemiologic Aspects written by James Wilson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977-12-01 with Science categories.
Modification of embryonic development by genetic differences in the mother is a well-regcognized phemomenon, but little is known about the genet ics of these maternal traits or the mechanisms by which they act. To illustrate the genetic approach to the problem, examples are given of how differences in embryonic response to a teratogen can be partitioned into those resulting from differences in embryonic genotype (including the possible role of X-linked genes in producing reciprocal cross differences), maternal genotype, and cytoplasmically transmitted factors. The advantages and limitations of analysis by appropriate crosses, in utero treatments, embryo transfers, and in vitro experiments are illustrated. The numerous inbred strains of the mouse, with well-documented physiology, the recently developed recombinant inbred strains, and the existence of easily identified biochemical marker genes offer at tractive opportunities, so far largely unexploited, for causal analysis of mater nal effects on teratological responses. VII. ADDENDUM Since this chapter was written, several relevant papers have appeared. The strain difference between AI] and C57BU6] mice in frequency of cleft-palate response to cortisone was fitted to a model of normally distributed log tolerance (Biddle and Fraser, 1976). Genetic differences, both in maternal uterine environment and embryonic response, can be represented in terms of their effect on the median effective dose required for the cleft-palate re sponse. The maternal effect of AI] dams relative to C57BU6] dams caused a two-fold reduction in embryonic tolerance to cortisone-induced cleft palate.
General Principles And Etiology
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Author : James Wilson
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
General Principles And Etiology written by James Wilson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
In less than 40 years teratology has grown from a little known discipline concerned with studies on the effects of a few physical and chemical stresses on developing fish, amphibians, and birds, to a discipline embracing a vast accumulation of literature on experimental studies in many animal forms and the results of intensive scrutiny of human development under varied conditions, as well. Emphasis has shifted from preoccupation with descrip tions of anatomical defects to concern about subtle and interacting causative factors, to searches for the early reactions to these at the cellular and subcellu lar levels, and to identification of abnormality in the chemical, the functional, and the ultrastructural realms. These changes in orientation have quite naturally made necessary the recruitment of concepts, methods, and expertise from other disciplines. Hence the foundations of teratology, which once were largely morphological, have extended into genetics, biochemistry, molecular biology, reproductive physiology, epidemiology, and several aspects of veteri nary and clinical medicine. It is not surprising that a student or new investigator approaching the field of teratology may feel some dismay when confronted with the confusing array of cross-disciplinary concepts and principles it encompasses today. One of the aims of this work is to introduce what the editors believe is a logical thread of continuity into a field that may be regarded by some as a welter of disordered information.
Teratology And Congenital Malformations
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Author : Lois Weinstein
language : en
Publisher:
Release Date : 1976
Teratology And Congenital Malformations written by Lois Weinstein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with categories.
Basic Concepts In Teratology
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Author : T. V. N. Persaud
language : en
Publisher: Alan R. Liss
Release Date : 1985
Basic Concepts In Teratology written by T. V. N. Persaud and has been published by Alan R. Liss this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Abnormalities categories.