Computational Approaches For Ageing And Age Related Diseases
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Computational Approaches For Ageing And Age Related Diseases
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Author : Stanley Durrleman
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-11
Computational Approaches For Ageing And Age Related Diseases written by Stanley Durrleman and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-11 with Science categories.
Aging And Aging Related Diseases
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Author : Zhao Wang
language : en
Publisher: Springer
Release Date : 2018-09-19
Aging And Aging Related Diseases written by Zhao Wang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-19 with Science categories.
This book provides an overview of recent advances in the study of aging and aging related diseases, discussing the topics at individual, organ, tissue, cell, and molecular levels. It also presents studies on the biomarkers of aging and anti-aging interventions. Aging has been becoming a global health problem. However it was not possible to determine aging as we usually diagnose a disease because there are few biomarkers for age estimation. Since ancient times, people have been seeking anti-aging substances and methods for achieving immortality, while the scientific study of aging has only existed for 100 years. This book appeals to researchers both in institutes and in pharmaceutical companies interested in further studies in this field.
Handbook Of The Biology Of Aging
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Author : Nicolas Musi
language : en
Publisher: Academic Press
Release Date : 2015-08-20
Handbook Of The Biology Of Aging written by Nicolas Musi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-20 with Medical categories.
Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of 'big data' approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to aging related problems. The book includes discussions on longevity pathways and interventions that modulate aging, innovative new tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, new strategies to pharmacologically modulate the mTOR pathway to delay aging, the importance of sirtuins and the hypoxic response in aging, and how various pathways interact within the context of aging as a complex genetic trait, amongst others. - Covers the key areas in biological gerontology research in one volume, with an 80% update from the previous edition - Edited by Matt Kaeberlein and George Martin, highly respected voices and researchers within the biology of aging discipline - Assists basic researchers in keeping abreast of research and clinical findings outside their subdiscipline - Presents information that will help medical, behavioral, and social gerontologists in understanding what basic scientists and clinicians are discovering - New chapters on genetics, evolutionary biology, bone aging, and epigenetic control - Provides a close examination of the diverse research being conducted today in the study of the biology of aging, detailing recent breakthroughs and potential new directions
Aging And Health A Systems Biology Perspective
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Author : A. I. Yashin
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2014-10-14
Aging And Health A Systems Biology Perspective written by A. I. Yashin and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-14 with Medical categories.
Aging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic programming of aging, as a continuation of development, creates an interface between the genome and the environment. New research into the gut microbiome describes how this interface may operate in practice with marked consequences for a variety of disorders. This analysis is bolstered by a view of the aging organism as a whole, with conclusions about the mechanisms underlying resilience of the organism to change, and is expanded with a discussion of circadian rhythms in aging. Finally, the book presents an outlook for the development of interventions to delay or to reverse the features of aging. The publication is recommended to students, researchers as well as professionals dealing with public health and public policy related to an aging society.
Nih Almanac
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Author : National Institutes of Health (U.S.). Division of Public Information
language : en
Publisher:
Release Date : 1998
Nih Almanac written by National Institutes of Health (U.S.). Division of Public Information and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Federal aid to medical care research categories.
A Multimodal End 2 End Approach To Accessible Computing
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Author : Pradipta Biswas
language : en
Publisher: Springer
Release Date : 2015-07-16
A Multimodal End 2 End Approach To Accessible Computing written by Pradipta Biswas and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-16 with Computers categories.
This book illustrates how Interactive Systems can help elderly and disabled populations engage with the world around them by finding methods of overcoming the difficulties these communities face when using such systems by presenting the latest in state-of-the-art technology and providing a vision for accessibility for the near future. The challenges faced by accessibility practitioners are discussed and the different phases of delivering accessible products and services are explored. A collection of eminent researchers from around the world cover topics on developing and standardizing user models for inclusive design, adaptable multimodal system development for digital TV and ubiquitous devices, presenting research on intelligent voice recognition, adaptable pointing, browsing and navigation, and affect and gesture recognition. The research not only focuses on how these can be hugely beneficial to primary users, but often finding useful applications for their able-bodied counterparts. For this new edition, new chapters have been added focusing on the latest developments in games for the visually impaired, inclusive interfaces for the agricultural industry in India and technologies to improve accessibility in broadcasting in Japan. A Multimodal End-2-End Approach to Accessible Computing will be an invaluable resource for both researchers and practitioners alike.
Molecular Basis And Emerging Strategies For Anti Aging Interventions
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Author : Syed Ibrahim Rizvi
language : en
Publisher: Springer
Release Date : 2018-11-02
Molecular Basis And Emerging Strategies For Anti Aging Interventions written by Syed Ibrahim Rizvi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-02 with Medical categories.
This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences.
Theoretical And Clinical Geropharmacology
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Author :
language : en
Publisher: Academic Press
Release Date : 2025-10-01
Theoretical And Clinical Geropharmacology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-10-01 with Medical categories.
Theoretical and Clinical Geropharmacology, explores the emerging field of senotherapeutics, which focuses on targeting cellular senescence to reduce age-related diseases and promote healthy aging. Chapters in this new release include Senotherapeutics: Milestones, innovations, and future prospects, Game Changer: Navigating between challenges and hopes in Geropharmacology, Next-Gen Senotherapeutics: AI/ML-driven strategies for aging and age-related disorders, Pharmacological frontiers in senescence: Transforming senescence with drug repurposing, Pharmacological potential of calorie restriction mimetics in mitigating brain aging, Isothiocyanates from cruciferous plants as geroprotectors, and much more.Other chapters cover Cellular parabiosis as a senotherapeutic approach, Molecular imaging for senescent cells-targeted therapeutics in aging and age-related diseases, Mitochondria-associated membranes (MAMs) in age-related heart diseases, role of endoplasmic reticulum stress, Cellular senescence and senotherapeutics in cardiovascular diseases, Risk of senescence, polypharmacy, and their outcomes in elderly cardiovascular disease patients, Geropharmacology and gastrointestinal surgery, Oxygen-ozone adjunct therapy in aging and senescence-related disorders, and more. - Helps readers understand the nature of senotherapeutic agents and related cellular signaling cascades in health lifespan maintenance and age-associated pathologies - Includes discussions on how to pioneer new candidate senotherapeutic drugs that can be developed based on current scientific knowledge - Reveals how repurposed conventional drugs can be used in elderly patients - Proposes new drug-based therapeutic strategies suitable for this advanced age group
Machine Learning Approaches And Applications In Applied Intelligence For Healthcare Data Analytics
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Author : Abhishek Kumar
language : en
Publisher: CRC Press
Release Date : 2022-03-09
Machine Learning Approaches And Applications In Applied Intelligence For Healthcare Data Analytics written by Abhishek Kumar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-09 with Computers categories.
In the last two decades, machine learning has developed dramatically and is still experiencing a fast and everlasting change in paradigms, methodology, applications and other aspects. This book offers a compendium of current and emerging machine learning paradigms in healthcare informatics and reflects on their diversity and complexity. Machine Learning Approaches and Applications in Applied Intelligence for Healthcare Data Analytics presents a variety of techniques designed to enhance and empower multi-disciplinary and multi-institutional machine learning research. It provides many case studies and a panoramic view of data and machine learning techniques, providing the opportunity for novel insights and discoveries. The book explores the theory and practical applications in healthcare and includes a guided tour of machine learning algorithms, architecture design and interdisciplinary challenges. This book is useful for research scholars and students involved in critical condition analysis and computation models.
Entertainment Computing Icec 2012
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Author : Marc Herrlich
language : en
Publisher: Springer
Release Date : 2012-08-30
Entertainment Computing Icec 2012 written by Marc Herrlich and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-30 with Computers categories.
This book constitutes the refereed proceedings of the 11th International Conference on Entertainment Computing, ICEC 2012, held in Bremen, Germany, in September 2012. The 21 full papers, 13 short papers, 16 posters, 8 demos, 4 workshops, 1 tutorial and 3 doctoral consortium submissions presented were carefully reviewed and selected from 115 submissions. The papers are organized in topical sections on story telling; serious games (learning and training); self and identity, interactive performance; mixed reality and 3D worlds; serious games (health and social); player experience; tools and methods; user interface; demonstrations; industry demonstration; harnessing collective intelligence with games; game development and model-driven software development; mobile gaming, mobile life – interweaving the virtual and the real; exploring the challenges of ethics, privacy and trust in serious gaming; open source software for entertainment.