Aging And Aging Related Diseases

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Aging And Age Related Diseases

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Author : Michał Karasek
language : en
Publisher: Nova Publishers
Release Date : 2006

Aging And Age Related Diseases written by Michał Karasek and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Age factors in disease categories.

Ageing has become a great problem for many countries. Due to world-wide life prolongation the number of people over 6o years old has grown rapidly into a ten percent piece of the world population. The growing age of the world population raises many social, economical, and medical problems. The proportion of people in the economically active age groups to those who are over 65 is constantly decreasing. A major consequence of the increasing numbers of individuals in advanced age groups is increasing numbers of patients suffering from age-related diseases. The aim of this book is to present the basic data on human ageing as well as on age-related diseases.

Aging And Age Related Disorders

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Author : Stephen Bondy
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-02

Aging And Age Related Disorders written by Stephen Bondy and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-02 with Medical categories.

Features that characterize the aging process include the gradual accumulation of cell damage after prolonged exposure to oxidative and inflammatory events over a lifetime. In addition to the accretion of lesions, the intrinsic levels of pro-oxidant and aberrant immune responses are elevated with age. These adverse events are often further enhanced by the chronic and slow progressing diseases that characterize the senescent brain and cardiovascular system. The incidence of some disorders such as Alzheimer's disease and vascular diseases are sufficiently prevalent in the extreme elderly that these disorders can arguably be considered "normal". Aging and Aging-Related Disorders examines the interface between normal and pathological aging, and illustrates how this border can sometimes be diffuse. It explores and illustrates the processes underlying the means by which aging becomes increasingly associated with inappropriate levels of free radical activity and how this can serve as a platform for the progression of age-related diseases. The book provides chapters that examine the interactive relationship between systems in the body that can enhance or sometimes even limit cellular longevity. In addition, specific redox mechanisms in cells are discussed. Another important aspect for aging discussed here is the close relationship between the systems of the body and exposure to environmental influences of oxidative stress that can affect both cellular senescence and a cell’s nuclear DNA. What may be even more interesting to note is that these external stressors are not simply confined to illnesses usually associated with aging, but can be evident in maturing and young individuals. A broad range of internationally recognized experts have contributed to this book. Their aim is to successfully highlight emerging knowledge and therapy for the understanding of the basis and development of aging–related disorders.

Aging And Aging Related Diseases

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Author : Zhao Wang
language : en
Publisher: Springer
Release Date : 2018-09-19

Aging And Aging Related Diseases written by Zhao Wang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-19 with Science categories.

This book provides an overview of recent advances in the study of aging and aging related diseases, discussing the topics at individual, organ, tissue, cell, and molecular levels. It also presents studies on the biomarkers of aging and anti-aging interventions. Aging has been becoming a global health problem. However it was not possible to determine aging as we usually diagnose a disease because there are few biomarkers for age estimation. Since ancient times, people have been seeking anti-aging substances and methods for achieving immortality, while the scientific study of aging has only existed for 100 years. This book appeals to researchers both in institutes and in pharmaceutical companies interested in further studies in this field.

Aging And Age Related Disorders From Molecular Mechanisms To Therapies

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Author : Vladimir Titorenko
language : en
Publisher: MDPI
Release Date : 2019-08-19

Aging And Age Related Disorders From Molecular Mechanisms To Therapies written by Vladimir Titorenko and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-19 with Science categories.

Aging of unicellular and multicellular eukaryotic organisms is a convoluted biological phenomenon, which is manifested as an age-related functional decline caused by progressive dysregulation of certain cellular and organismal processes. Many chronic diseases are associated with human aging. These aging-associated diseases include cardiovascular diseases, chronic obstructive pulmonary disease, chronic kidney disease, diabetes, osteoarthritis, osteoporosis, sarcopenia, stroke, neurodegenerative diseases (including Parkinson’s, Alzheimer’s, and Huntington’s diseases), and many forms of cancer. Studies in yeast, roundworms, fruit flies, fishes, mice, primates, and humans have provided evidence that the major aspects and basic mechanisms of aging and aging-associated pathology are conserved across phyla. The focus of this International Journal of Molecular Sciences Special Issue is on molecular and cellular mechanisms, diagnostics, and therapies and diseases of aging. Fifteen original research and review articles in this Special Issue provide important insights into how various genetic, dietary, and pharmacological interventions can affect certain longevity-defining cellular and organismal processes to delay aging and postpone the onset of age-related pathologies in evolutionarily diverse organisms. These articles outline the most important unanswered questions and directions for future research in the vibrant and rapidly evolving fields of mechanisms of biological aging, aging-associated diseases, and aging-delaying therapies.

Prevention And Treatment Of Age Related Diseases

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Author : Suresh I.S. Rattan
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-09

Prevention And Treatment Of Age Related Diseases written by Suresh I.S. Rattan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-09 with Medical categories.

This book offers a broad-ranging assessment of current efforts of the molecular, cellular, hormonal, nutritional and lifestyle strategies being tested and applied by biogerontologists in the search for effective means of intervention, prevention and treatment of age-related diseases, and for achieving healthy old age. Employing a semi-academic style, the book presents data from experimental systems, while focusing primarily on their applications to humans in the prevention and treatment of age-related impairments.

Molecular Mechanisms Of Skin Aging And Age Related Diseases

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Author : Taihao Quan
language : en
Publisher: CRC Press
Release Date : 2016-04-21

Molecular Mechanisms Of Skin Aging And Age Related Diseases written by Taihao Quan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-21 with Medical categories.

Our skin changes as we age. It becomes thinner and loses fat, making it less plump and smooth. Clinically, aged skin is characterized by wrinkles, sagging, age spots and dryness. Emphasizing laboratory and clinical research, this book comprehensively describes the molecular mechanisms of human skin-aging and age-related skin diseases. This includes molecular understanding of the development of aging skin and its prevention as well as mechanisms-based clinical rejuvenation. The book also focuses on research to develop mechanisms-based anti-skin-aging products.

Aging And Age Related Disorders From Molecular Mechanisms To Therapies

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Author : Vladimir Titorenko
language : en
Publisher:
Release Date : 2019

Aging And Age Related Disorders From Molecular Mechanisms To Therapies written by Vladimir Titorenko and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Electronic books categories.

Aging of unicellular and multicellular eukaryotic organisms is a convoluted biological phenomenon, which is manifested as an age-related functional decline caused by progressive dysregulation of certain cellular and organismal processes. Many chronic diseases are associated with human aging. These aging-associated diseases include cardiovascular diseases, chronic obstructive pulmonary disease, chronic kidney disease, diabetes, osteoarthritis, osteoporosis, sarcopenia, stroke, neurodegenerative diseases (including Parkinson's, Alzheimer's, and Huntington's diseases), and many forms of cancer. Studies in yeast, roundworms, fruit flies, fishes, mice, primates, and humans have provided evidence that the major aspects and basic mechanisms of aging and aging-associated pathology are conserved across phyla. The focus of this International Journal of Molecular Sciences Special Issue is on molecular and cellular mechanisms, diagnostics, and therapies and diseases of aging. Fifteen original research and review articles in this Special Issue provide important insights into how various genetic, dietary, and pharmacological interventions can affect certain longevity-defining cellular and organismal processes to delay aging and postpone the onset of age-related pathologies in evolutionarily diverse organisms. These articles outline the most important unanswered questions and directions for future research in the vibrant and rapidly evolving fields of mechanisms of biological aging, aging-associated diseases, and aging-delaying therapies.

Inflammation Aging And Oxidative Stress

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Author : Stephen C. Bondy
language : en
Publisher: Springer
Release Date : 2016-12-14

Inflammation Aging And Oxidative Stress written by Stephen C. Bondy and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-14 with Science categories.

The book describes the major degenerative processes and pathologies exacerbated by senescence and how they can be alleviated through retardation of cellular aging. Topics discussed include neurodegenerative disease, protein oxidation, cerebrovascular disease, particle-induced inflammation and cardiovascular disease, Alzheimer’s disease, ovarian aging, dietary and endogenous anti-oxidants in management of Parkinson’s disease, and effects of exercise on oxidation and inflammation. The nineteen expertly authored chapters are organized into three sections in order to present a complete picture to the reader: Age Related Cellular Events, Role of Inflammatory and Oxidative Processes in Age-Related Diseases, and Retardation of Cellular Aging. Inflammation, Oxidative Stress and Age-Related Disease draws from a variety of international perspectives and provides a comprehensive overview of the relationship between disease, cell aging, and oxidative stress, as well as potential for preventing or slowing these processes. This installment of Springer’s Oxidative Stress in Applied Basic Research and Clinical Practice is ideal for researchers, clinicians, and advanced graduate students in the fields of cardiology, neuroscience, biogerontolgy, and cell biology.

The Role Of Antioxidants In Longevity And Age Related Diseases

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Author : Bee Ling Tan
language : en
Publisher: Springer Nature
Release Date : 2021-11-19

The Role Of Antioxidants In Longevity And Age Related Diseases written by Bee Ling Tan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-19 with Family & Relationships categories.

The average life expectancy has increased worldwide in the recent decades. This has presented new challenges as old age brings the onset of diseases such as cancer, neurodegenerative disorders, cardiovascular disease, type 2 diabetes, arthritis, osteoporosis, stroke, and Alzheimer’s disease. Studies and research have shown the potential preventive and therapeutic roles of antioxidants in aging and age-related diseases by inhibiting the formation or disrupting the propagation of free radicals and thus increasing healthy longevity, enhancing immune function, and decreasing oxidative stress. This has made an antioxidant rich diet of increasing importance in battling the detrimental effects of the aging process. “The Role of Antioxidants in Longevity and Age-Related Diseases” is the book that compiles research on antioxidants and their biological mechanisms that mediate age-related diseases. This book covers the major issues linked to antioxidants, aging, and age-related diseases, including changes in organ systems over the lifespan, age-related oxidative stress-induced redox imbalance, inflammaging, implications of inflammation in aging and age-related diseases, and the important role of antioxidant-rich foods in their prevention and treatment of various age-related diseases. For researchers seeking a comprehensive single source on antioxidants and their roles in aging and age-related diseases, this novel text provides an up-to-date overview.

Aging Interventions And Therapies

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Author : Suresh I S Rattan
language : en
Publisher: World Scientific
Release Date : 2005-05-06

Aging Interventions And Therapies written by Suresh I S Rattan and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-06 with Science categories.

' This comprehensive volume surveys the molecular, cellular, hormonal, nutritional, medical and lifestyle strategies being tested and applied for the prevention, intervention and treatment of age-related diseases. With authoritative contributions not just from researchers in academic institutions and pharmaceutical and cosmeceutical industries, but also practicing clinicians of both mainstream and alternative medicine, demographers and bioethicists, this book provides unique scientific, ethical and social perspectives on the discussion of aging intervention. In addition, the latest technologies in development, which will have serious bearings on future aging interventions, are reviewed. Aging Interventions and Therapies is ideal for graduates and undergraduates in universities and medical and nursing colleges, as well as post-graduates researching different aspects of aging and anti-aging. The topics covered are also highly relevant for professionals in the pharmaceutical, cosmeceutical, nutrition and healthcare industries, and practicing clinicians looking for a reliable and up-to-date resource on aging intervention and therapy. Contents:The Ethics of Aging Intervention and Life-Extension (S Horrobin)Prevention and Treatment of Skin Aging (J L McCullogh & K M Kelly)Industrial Approaches Towards Developing Effective Skin Care Products (T Blatt et al.)Strategies to Reduce Age-Related Skeletal Muscle Wasting (G S Lynch et al.)Antioxidants and Aging in Human Beings (É Le Bourg)Hormone Therapy for Aging (M K Thakur)Pineal Peptides as Modulators of Aging (V N Anisimov & V K Khavinson)Melatonin: Anti-Aging Perception and Current Perspectives (A L Bhatia)Zinc and Other Micronutrients for Healthy Aging (E Mocchegiani et al.)Calorie Restriction as a Potent Anti-Aging Intervention: Modulation of Oxidative Stress (B P Yu)Nutritional Interventions in Aging and Age-Associated Disorders (K Kitani)Telomere- and Telomerase Based Therapies (M A Cerone et al.)Clinical Perspective of the Present Status of Treatment for Major Age-Related Diseases (A Syngle)Indian Ayurvedic Medicine in Aging Prevention and Treatment (B P S Vohra & S K Gupta)Alzheimer's Disease: Current and Future Treatments (U Kumar)Stem Cells, Regenerative Medicine and Aging (M Kassem)Principles and Practice of Hormesis as an Aging Intervention (S I S Rattan)Forseeable and More Distant Rejuvenation Therapies (A D N J de Grey)Anti-Aging Medicine and the Quest for Immortality (S J Olshansky & B A Carnes) Readership: Graduate and undergraduate students, researchers, and professionals working in the healthcare, cosmetics and cosmeceutical industries. Keywords:Aging;Anti-Aging;Lifespan;Longevity;Healthy Aging;Gerontogenes;Exercise;StressKey Features:Provides state-of-the-art information on the success and failure of various anti-aging approaches, such as hormone therapy, melatonin, biopeptides, nutrition, antioxidants, micronutrients, herbs, exercise and cosmeticsChallenges and re-defines common beliefs and ideas about aging intervention and lifespan prolongationEvaluates the advantages and disadvantages of prevalent treatments for age-related diseasesEvaluates therapeutic approaches under test and development against Alzheimer's disease, mitochondrial diseases, and for better skin careReviews:“This book tackles a frontier medicine and has the merit to have harmoniously ‘cross-linked’ opinion leaders in many different aspects of the field, rendering it very amenable to students, basic scientists and clinicians, and is an absolute must for the dedicated researchers.”Biogerontology '