Computational Methods In Biomedical Research
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Computational Methods In Biomedical Research
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Author : Ravindra Khattree
language : en
Publisher: CRC Press
Release Date : 2007-12-12
Computational Methods In Biomedical Research written by Ravindra Khattree and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-12 with Mathematics categories.
Continuing advances in biomedical research and statistical methods call for a constant stream of updated, cohesive accounts of new developments so that the methodologies can be properly implemented in the biomedical field. Responding to this need, Computational Methods in Biomedical Research explores important current and emerging computational statistical methods that are used in biomedical research. Written by active researchers in the field, this authoritative collection covers a wide range of topics. It introduces each topic at a basic level, before moving on to more advanced discussions of applications. The book begins with microarray data analysis, machine learning techniques, and mass spectrometry-based protein profiling. It then uses state space models to predict US cancer mortality rates and provides an overview of the application of multistate models in analyzing multiple failure times. The book also describes various Bayesian techniques, the sequential monitoring of randomization tests, mixed-effects models, and the classification rules for repeated measures data. The volume concludes with estimation methods for analyzing longitudinal data. Supplying the knowledge necessary to perform sophisticated statistical analyses, this reference is a must-have for anyone involved in advanced biomedical and pharmaceutical research. It will help in the quest to identify potential new drugs for the treatment of a variety of diseases.
Computational Methods In Biophysics Biomaterials Biotechnology And Medical Systems
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Author : Cornelius T. Leondes
language : en
Publisher: Springer Nature
Release Date : 2006-09-21
Computational Methods In Biophysics Biomaterials Biotechnology And Medical Systems written by Cornelius T. Leondes and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-21 with Technology & Engineering categories.
The cross-disciplinary pursuits between modern technology, their computations and applications to the human body have exploded because of rapid developments in computer technology and mathematical computational techniques. This four-volume set, Computational Methods in Biophysics, Biomaterials, Biotechnology and Medical Systems, represents the first multi-volume treatment of this significant subject on the international scene. The work is an indispensable reference source by leading researchers, and is essential reference work for academics, practitioners, students and researchers working with: *Computers in Medicine, *Science and Mathematics in Biomaterials, Biomechanics and Bioengineering, *Computational Biophysics.
Bayesian Computational Methods In Biomedical Research
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Author : Hedibert Freitas Lopes
language : en
Publisher:
Release Date : 2007
Bayesian Computational Methods In Biomedical Research written by Hedibert Freitas Lopes and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Mathematical statistics categories.
High Performance Computational Methods For Biological Sequence Analysis
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Author : Tieng K. Yap
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
High Performance Computational Methods For Biological Sequence Analysis written by Tieng K. Yap and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Computers categories.
High Performance Computational Methods for Biological Sequence Analysis presents biological sequence analysis using an interdisciplinary approach that integrates biological, mathematical and computational concepts. These concepts are presented so that computer scientists and biomedical scientists can obtain the necessary background for developing better algorithms and applying parallel computational methods. This book will enable both groups to develop the depth of knowledge needed to work in this interdisciplinary field. This work focuses on high performance computational approaches that are used to perform computationally intensive biological sequence analysis tasks: pairwise sequence comparison, multiple sequence alignment, and sequence similarity searching in large databases. These computational methods are becoming increasingly important to the molecular biology community allowing researchers to explore the increasingly large amounts of sequence data generated by the Human Genome Project and other related biological projects. The approaches presented by the authors are state-of-the-art and show how to reduce analysis times significantly, sometimes from days to minutes. High Performance Computational Methods for Biological Sequence Analysis is tremendously important to biomedical science students and researchers who are interested in applying sequence analyses to their studies, and to computational science students and researchers who are interested in applying new computational approaches to biological sequence analyses.
Computational Methods In Molecular Biology
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Author : S.L. Salzberg
language : en
Publisher: Elsevier
Release Date : 1998-06-19
Computational Methods In Molecular Biology written by S.L. Salzberg and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-06-19 with Science categories.
Computational biology is a rapidly expanding field, and the number and variety of computational methods used for DNA and protein sequence analysis is growing every day. These algorithms are extremely valuable to biotechnology companies and to researchers and teachers in universities.This book explains the latest computer technology for analyzing DNA, RNA, and protein sequences. Clear and easy to follow, designed specifically for the non-computer scientist, it will help biologists make better choices on which algorithm to use. New techniques and demonstrations are elucidated, as are state-of-the-art problems, and more advanced material on the latest algorithms.The primary audience for this volume are molecular biologists working either in biotechnology companies or academic research environments, individual researchers and the institutions they work for, and students. Any biologist who relies on computers should want this book.A secondary audience will be computer scientists developing techniques with applications in biology.An excellent reference for leading techniques, it will also help introduce computer scientists to the biology problems. This is an outstanding work which will be ideal for the increasing number of scientists moving into computational biology.
Computational Methods In Genome Research
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Author : Sándor Suhai
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Computational Methods In Genome Research written by Sándor Suhai and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The application of computational methods to solve scientific and pratical problems in genome research created a new interdisciplinary area that transcends boundaries traditionally separating genetics, biology, mathematics, physics, and computer science. Computers have been, of course, intensively used for many year~ in the field of life sciences, even before genome research started, to store and analyze DNA or proteins sequences, to explore and model the three-dimensional structure, the dynamics and the function of biopolymers, to compute genetic linkage or evolutionary processes etc. The rapid development of new molecular and genetic technologies, combined with ambitious goals to explore the structure and function of genomes of higher organisms, has generated, however, not only a huge and burgeoning body of data but also a new class of scientific questions. The nature and complexity of these questions will require, beyond establishing a new kind of alliance between experimental and theoretical disciplines, also the development of new generations both in computer software and hardware technologies, respectively. New theoretical procedures, combined with powerful computational facilities, will substantially extend the horizon of problems that genome research can ·attack with success. Many of us still feel that computational models rationalizing experimental findings in genome research fulfil their promises more slowly than desired. There also is an uncertainity concerning the real position of a 'theoretical genome research' in the network of established disciplines integrating their efforts in this field.
Computational And Experimental Biomedical Sciences Methods And Applications
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Author : João Manuel R. S. Tavares
language : en
Publisher: Springer
Release Date : 2015-03-16
Computational And Experimental Biomedical Sciences Methods And Applications written by João Manuel R. S. Tavares and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-16 with Technology & Engineering categories.
This book contains the full papers presented at ICCEBS 2013 – the 1st International Conference on Computational and Experimental Biomedical Sciences, which was organized in Azores, in October 2013. The included papers present and discuss new trends in those fields, using several methods and techniques, including active shape models, constitutive models, isogeometric elements, genetic algorithms, level sets, material models, neural networks, optimization and the finite element method, in order to address more efficiently different and timely applications involving biofluids, computer simulation, computational biomechanics, image based diagnosis, image processing and analysis, image segmentation, image registration, scaffolds, simulation and surgical planning. The main audience for this book consists of researchers, Ph.D students and graduate students with multidisciplinary interests related to the areas of artificial intelligence, bioengineering, biology, biomechanics, computational fluid dynamics, computational mechanics, computational vision, histology, human motion, imagiology, applied mathematics, medical image, medicine, orthopaedics, rehabilitation, speech production and tissue engineering.
Computational Methods With Applications In Bioinformatics Analysis
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Author : Jeffrey J P Tsai
language : en
Publisher: World Scientific
Release Date : 2017-06-09
Computational Methods With Applications In Bioinformatics Analysis written by Jeffrey J P Tsai and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-09 with Science categories.
This compendium contains 10 chapters written by world renowned researchers with expertise in semantic computing, genome sequence analysis, biomolecular interaction, time-series microarray analysis, and machine learning algorithms.The salient feature of this book is that it highlights eight types of computational techniques to tackle different biomedical applications. These techniques include unsupervised learning algorithms, principal component analysis, fuzzy integral, graph-based ensemble clustering method, semantic analysis, interolog approach, molecular simulations and enzyme kinetics.The unique volume will be a useful reference material and an inspirational read for advanced undergraduate and graduate students, computer scientists, computational biologists, bioinformatics and biomedical professionals.
Essential Numerical Computer Methods
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Author : Michael L. Johnson
language : en
Publisher: Academic Press
Release Date : 2010-11-25
Essential Numerical Computer Methods written by Michael L. Johnson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-25 with Mathematics categories.
The use of computers and computational methods has become ubiquitous in biological and biomedical research. During the last 2 decades most basic algorithms have not changed, but what has is the huge increase in computer speed and ease of use, along with the corresponding orders of magnitude decrease in cost. A general perception exists that the only applications of computers and computer methods in biological and biomedical research are either basic statistical analysis or the searching of DNA sequence data bases. While these are important applications they only scratch the surface of the current and potential applications of computers and computer methods in biomedical research. The various chapters within this volume include a wide variety of applications that extend far beyond this limited perception. As part of the Reliable Lab Solutions series, Essential Numerical Computer Methods brings together chapters from volumes 210, 240, 321, 383, 384, 454, and 467 of Methods in Enzymology. These chapters provide a general progression from basic numerical methods to more specific biochemical and biomedical applications. - The various chapters within this volume include a wide variety of applications that extend far beyond this limited perception - As part of the Reliable Lab Solutions series, Essential Numerical Computer Methods brings together chapters from volumes 210, 240, 321, 383, 384, 454, and 467 of Methods in Enzymology - These chapters provide a general progression from basic numerical methods to more specific biochemical and biomedical applications
Computational Methods For Rational Drug Design
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Author : Mithun Rudrapal
language : en
Publisher: John Wiley & Sons
Release Date : 2024-12-06
Computational Methods For Rational Drug Design written by Mithun Rudrapal and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-06 with Science categories.
Comprehensive resource covering computational tools and techniques for the development of cost-effective drugs to combat diseases, with specific disease examples Computational Methods for Rational Drug Design covers the tools and techniques of drug design with applications to the discovery of small molecule-based therapeutics, detailing methodologies and practical applications and addressing the challenges of techniques like AI/ML and drug design for unknown receptor structures. Divided into 23 chapters, the contributors address various cutting-edge areas of therapeutic importance such as neurodegenerative disorders, cancer, multi-drug resistant bacterial infections, inflammatory diseases, and viral infections. Edited by a highly qualified academic with significant research contributions to the field, Computational Methods for Rational Drug Design explores topics including: Computer-assisted methods and tools for structure- and ligand-based drug design, virtual screening and lead discovery, and ADMET and physicochemical assessments In silico and pharmacophore modeling, fragment-based design, de novo drug design and scaffold hopping, network-based methods and drug discovery Rational design of natural products, peptides, enzyme inhibitors, drugs for neurodegenerative disorders, anti-inflammatory therapeutics, antibacterials for multi-drug resistant infections, and antiviral and anticancer therapeutics Protac and protide strategies in drug design, intrinsically disordered proteins (IDPs) in drug discovery and lung cancer treatment through ALK receptor-targeted drug metabolism and pharmacokinetics Helping readers seamlessly navigate the challenges of drug design, Computational Methods for Rational Drug Design is an essential reference for pharmaceutical and medicinal chemists, biochemists, pharmacologists, and phytochemists, along with molecular modeling and computational drug discovery professionals.