Computational Modeling In Bioengineering And Bioinformatics


Computational Modeling In Bioengineering And Bioinformatics
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Computational Modeling In Bioengineering And Bioinformatics


Computational Modeling In Bioengineering And Bioinformatics
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Author : Nenad Filipovic
language : en
Publisher: Academic Press
Release Date : 2019-10-09

Computational Modeling In Bioengineering And Bioinformatics written by Nenad Filipovic and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-09 with Science categories.


Computational Modeling in Bioengineering and Bioinformatics promotes complementary disciplines that hold great promise for the advancement of research and development in complex medical and biological systems, and in the environment, public health, drug design, and so on. It provides a common platform by bridging these two very important and complementary disciplines into an interactive and attractive forum. Chapters cover biomechanics and bioimaging, biomedical decision support system, data mining, personalized diagnoses, bio-signal processing, protein structure prediction, tissue and cell engineering, biomedical image processing, analysis and visualization, high performance computing and sports bioengineering. The book's chapters are the result of many international projects in the area of bioengineering and bioinformatics done at the Research and Development Center for Bioengineering BioIRC and by the Faculty of Engineering at the University of Kragujevac, Serbia. Presents recent advances at the crossroads of biomedical engineering and bioinformatics, one of the hottest areas in biomedical and clinical research Discusses a wide range of leading-edge research topics, including biomechanics and bioimaging, biomedical decision support systems, data mining, personalized diagnoses, bio-signal processing, protein structure prediction, tissue and cell engineering, amongst others Includes coverage of biomechanical, bioengineering and computational methods of treatment and diagnosis



Computational Bioengineering And Bioinformatics


Computational Bioengineering And Bioinformatics
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Author : Nenad Filipovic
language : en
Publisher: Springer Nature
Release Date : 2020-03-11

Computational Bioengineering And Bioinformatics written by Nenad Filipovic and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-11 with Technology & Engineering categories.


This book explores the latest and most relevant topics in the field of computational bioengineering and bioinformatics, with a particular focus on patient-specific, disease-progression modeling. It covers computational methods for cardiovascular disease prediction, with an emphasis on biomechanics, biomedical decision support systems, data mining, personalized diagnostics, bio-signal processing, protein structure prediction, biomedical image processing, analysis and visualization, and high-performance computing. It also discusses state-of-the-art tools for disease characterization, and recent advances in areas such as biomechanics, cardiovascular engineering, patient-specific modeling, population-based modeling, multiscale modeling, image processing, data mining, biomedical decision-support systems, signal processing, biomaterials and dental biomechanics, tissue and cell engineering, computational chemistry and high-performance computing. As such, it is a valuable resource for researchers, medical and bioengineering students, and medical device and software experts



Uncertainty In Biology


Uncertainty In Biology
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Author : Liesbet Geris
language : en
Publisher: Springer
Release Date : 2015-10-26

Uncertainty In Biology written by Liesbet Geris and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-26 with Technology & Engineering categories.


Computational modeling allows to reduce, refine and replace animal experimentation as well as to translate findings obtained in these experiments to the human background. However these biomedical problems are inherently complex with a myriad of influencing factors, which strongly complicates the model building and validation process. This book wants to address four main issues related to the building and validation of computational models of biomedical processes: 1. Modeling establishment under uncertainty 2. Model selection and parameter fitting 3. Sensitivity analysis and model adaptation 4. Model predictions under uncertainty In each of the abovementioned areas, the book discusses a number of key-techniques by means of a general theoretical description followed by one or more practical examples. This book is intended for graduate students and researchers active in the field of computational modeling of biomedical processes who seek to acquaint themselves with the different ways in which to study the parameter space of their model as well as its overall behavior.



Computational Modeling Of Gene Regulatory Networks


Computational Modeling Of Gene Regulatory Networks
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Author : Hamid Bolouri
language : en
Publisher: Imperial College Press
Release Date : 2008

Computational Modeling Of Gene Regulatory Networks written by Hamid Bolouri and has been published by Imperial College Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.


This book serves as an introduction to the myriad computational approaches to gene regulatory modeling and analysis, and is written specifically with experimental biologists in mind. Mathematical jargon is avoided and explanations are given in intuitive terms. In cases where equations are unavoidable, they are derived from first principles or, at the very least, an intuitive description is provided. Extensive examples and a large number of model descriptions are provided for use in both classroom exercises as well as self-guided exploration and learning. As such, the book is ideal for self-learning and also as the basis of a semester-long course for undergraduate and graduate students in molecular biology, bioengineering, genome sciences, or systems biology.



Computational Modeling Of Biological Systems


Computational Modeling Of Biological Systems
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Author : Nikolay V Dokholyan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-02-12

Computational Modeling Of Biological Systems written by Nikolay V Dokholyan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-12 with Science categories.


Computational modeling is emerging as a powerful new approach to study and manipulate biological systems. Multiple methods have been developed to model, visualize, and rationally alter systems at various length scales, starting from molecular modeling and design at atomic resolution to cellular pathways modeling and analysis. Higher time and length scale processes, such as molecular evolution, have also greatly benefited from new breeds of computational approaches. This book provides an overview of the established computational methods used for modeling biologically and medically relevant systems.



Modeling In Computational Biology And Biomedicine


Modeling In Computational Biology And Biomedicine
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Author : Frédéric Cazals
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-06

Modeling In Computational Biology And Biomedicine written by Frédéric Cazals and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-06 with Mathematics categories.


Computational biology, mathematical biology, biology and biomedicine are currently undergoing spectacular progresses due to a synergy between technological advances and inputs from physics, chemistry, mathematics, statistics and computer science. The goal of this book is to evidence this synergy by describing selected developments in the following fields: bioinformatics, biomedicine and neuroscience. This work is unique in two respects - first, by the variety and scales of systems studied and second, by its presentation: Each chapter provides the biological or medical context, follows up with mathematical or algorithmic developments triggered by a specific problem and concludes with one or two success stories, namely new insights gained thanks to these methodological developments. It also highlights some unsolved and outstanding theoretical questions, with a potentially high impact on these disciplines. Two communities will be particularly interested in this book. The first one is the vast community of applied mathematicians and computer scientists, whose interests should be captured by the added value generated by the application of advanced concepts and algorithms to challenging biological or medical problems. The second is the equally vast community of biologists. Whether scientists or engineers, they will find in this book a clear and self-contained account of concepts and techniques from mathematics and computer science, together with success stories on their favorite systems. The variety of systems described represents a panoply of complementary conceptual tools. On a practical level, the resources listed at the end of each chapter (databases, software) offer invaluable support for getting started on a specific topic in the fields of biomedicine, bioinformatics and neuroscience.



Modeling In Computational Biology And Biomedicine


Modeling In Computational Biology And Biomedicine
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Author : D. Ric Cazals
language : en
Publisher:
Release Date : 2012-11-08

Modeling In Computational Biology And Biomedicine written by D. Ric Cazals and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-08 with categories.




Computational Models In Biomedical Engineering


Computational Models In Biomedical Engineering
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Author : Milos Kojic
language : en
Publisher: Academic Press
Release Date : 2022-09-11

Computational Models In Biomedical Engineering written by Milos Kojic and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-11 with Science categories.


Computational Models in Biomedical Engineering: Finite Element Models Based on Smeared Physical Fields: Theory, Solutions, and Software discusses novel computational methodologies developed by the authors that address a variety of topics in biomedicine, with concepts that rely on the so-called smeared physical field built into the finite element method. A new and straightforward methodology is represented by their Kojic Transport Model (KTM), where a composite smeared finite element (CSFE) as a FE formulation contains different fields (e.g., drug concentration, electrical potential) in a composite medium, such as tissue, which includes the capillary and lymphatic system, different cell groups and organelles. The continuum domains participate in the overall model according to their volumetric fractions. The governing laws and material parameters are assigned to each of the domains. Furthermore, the continuum fields are coupled at each FE node by connectivity elements which take into account biological barriers such as vessel walls and cells. Provides a methodology based on the smeared concept within the finite element method which is simple, straightforward and easy to use Enables the modeling of complex physical field problems and the mechanics of biological systems Includes features that are illustrated in chapters devoted to applications surrounding tissue, heart and lung Includes a methodology that can serve as a basis for further enhancements by including additional phenomena which can be described by relevant relationships, derived theoretically or experimentally observed in laboratories and clinics



Computational Systems Bioinformatics Methods And Biomedical Applications


Computational Systems Bioinformatics Methods And Biomedical Applications
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Author : Wong Stephen Tin Chi
language : en
Publisher: World Scientific Publishing Company
Release Date : 2008-01-02

Computational Systems Bioinformatics Methods And Biomedical Applications written by Wong Stephen Tin Chi and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-02 with Science categories.


Computational systems biology is a new and rapidly developing field of research, concerned with understanding the structure and processes of biological systems at the molecular, cellular, tissue, and organ levels through computational modeling as well as novel information theoretic data and image analysis methods. By focusing on either information processing of biological data or on modeling physical and chemical processes of biosystems, and in combination with the recent breakthrough in deciphering the human genome, computational systems biology is guaranteed to play a central role in disease prediction and preventive medicine, gene technology and pharmaceuticals, and other biotechnology fields.This book begins by introducing the basic mathematical, statistical, and data mining principles of computational systems biology, and then presents bioinformatics technology in microarray and sequence analysis step-by-step. Offering an insightful look into the effectiveness of the systems approach in computational biology, it focuses on recurrent themes in bioinformatics, biomedical applications, and future directions for research.



Computational Systems Bioinformatics


Computational Systems Bioinformatics
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Author : Xiaobo Zhou
language : en
Publisher: World Scientific
Release Date : 2008

Computational Systems Bioinformatics written by Xiaobo Zhou and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Science categories.


Computational systems biology is a new and rapidly developing field of research, concerned with understanding the structure and processes of biological systems at the molecular, cellular, tissue, and organ levels through computational modeling as well as novel information theoretic data and image analysis methods. By focusing on either information processing of biological data or on modeling physical and chemical processes of biosystems, and in combination with the recent breakthrough in deciphering the human genome, computational systems biology is guaranteed to play a central role in disease prediction and preventive medicine, gene technology and pharmaceuticals, and other biotechnology fields. This book begins by introducing the basic mathematical, statistical, and data mining principles of computational systems biology, and then presents bioinformatics technology in microarray and sequence analysis step-by-step. Offering an insightful look into the effectiveness of the systems approach in computational biology, it focuses on recurrent themes in bioinformatics, biomedical applications, and future directions for research.