[PDF] Computational Tools In Inferring Cancer Tissue Of Origin And Molecular Classification Towards Personalized Cancer Therapy Volume Ii - eBooks Review

Computational Tools In Inferring Cancer Tissue Of Origin And Molecular Classification Towards Personalized Cancer Therapy Volume Ii


Computational Tools In Inferring Cancer Tissue Of Origin And Molecular Classification Towards Personalized Cancer Therapy Volume Ii
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Computational Tools In Inferring Cancer Tissue Of Origin And Molecular Classification Towards Personalized Cancer Therapy Volume Ii


Computational Tools In Inferring Cancer Tissue Of Origin And Molecular Classification Towards Personalized Cancer Therapy Volume Ii
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Author : Min Tang
language : en
Publisher: Frontiers Media SA
Release Date : 2021-09-30

Computational Tools In Inferring Cancer Tissue Of Origin And Molecular Classification Towards Personalized Cancer Therapy Volume Ii written by Min Tang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-30 with Science categories.




Computational Tools In Inferring Cancer Tissue Of Origin And Molecular Classification Towards Personalized Cancer Therapy Volume Iii


Computational Tools In Inferring Cancer Tissue Of Origin And Molecular Classification Towards Personalized Cancer Therapy Volume Iii
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Author : Min Tang
language : en
Publisher: Frontiers Media SA
Release Date : 2024-09-25

Computational Tools In Inferring Cancer Tissue Of Origin And Molecular Classification Towards Personalized Cancer Therapy Volume Iii written by Min Tang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-25 with Science categories.


Our second Research Topic in this series, Computational tools in inferring cancer tissue-of-origin and molecular classification towards personalized cancer therapy, Volume II (https://fro.ntiers.in/14361) has over 8 accepted articles and further manuscripts currently under review. Due to the continued success of these Research Topics and the interest in the subject, we will launch a third volume on the same topic. Inferring cancer tissue-of-origin and molecular classification are two critical problems in personalized cancer therapy. It is known that there are about 5% cancers of unknown primary (CUP) site. These kinds of patients are under empirical chemotherapy, which leads to a very low survival rate. Thus, it is important to infer cancer tissue-of-origin. However, experimental methods usually fail to identify the exact tissue-of-origin even after the death of a patient, which provides a need for computational methods especially in the era of big biomedical data. Based on the finding that gene expressions of metastasis cancer cells are more similar to those of original tissue than metastasis tissue, there have been a few computational methods developed in this area. However, the accuracy of the methods is yet to be improved to assure a clinical usage. In addition to CUP, inferring cancer tissue-of-origin is also important in avoiding misdiagnosis even if the cancer origin is known.



Index Medicus


Index Medicus
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Author :
language : en
Publisher:
Release Date : 2004

Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medicine categories.


Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.



Computational Methods In Inferring Cancer Tissue Of Origin And Cancer Molecular Classification Volume I


Computational Methods In Inferring Cancer Tissue Of Origin And Cancer Molecular Classification Volume I
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Author : Min Tang
language : en
Publisher: Frontiers Media SA
Release Date : 2021-04-01

Computational Methods In Inferring Cancer Tissue Of Origin And Cancer Molecular Classification Volume I written by Min Tang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-01 with Science categories.




Advances In Mathematical And Computational Oncology Volume Ii


Advances In Mathematical And Computational Oncology Volume Ii
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Author : George Bebis
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-27

Advances In Mathematical And Computational Oncology Volume Ii written by George Bebis and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-27 with Science categories.




Bioinformatics Tools And Web Server For Cancer Biomarker Development Volume Ii


Bioinformatics Tools And Web Server For Cancer Biomarker Development Volume Ii
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Author : Xiangqian Guo
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-16

Bioinformatics Tools And Web Server For Cancer Biomarker Development Volume Ii written by Xiangqian Guo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-16 with Science categories.




Cancer Genetics And Genomics For Personalized Medicine


Cancer Genetics And Genomics For Personalized Medicine
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Author : Il-Jin Kim
language : en
Publisher: CRC Press
Release Date : 2017-04-11

Cancer Genetics And Genomics For Personalized Medicine written by Il-Jin Kim and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-11 with Medical categories.


This book covers almost all fields of cancer genetics and genomics for personalized medicine. Targeted therapy, or precision medicine, or personalized medicine is becoming a standard treatment for many diseases, including cancer. However, how much do we know about the personalized medicine approach? This lucid book helps undergraduate and graduate students, professional researchers, and clinicians to better understand the key concept of personalized medicine. The most up-to-date topics on personalized medicine in this book cover the recent trends in and updates on lung, gastric, liver, breast, and other types of cancers. Circulating tumor cell, cell-free circulating DNA, and microRNAs are discussed as new diagnostic and prognostic markers for cancer. The avatar mouse model is also discussed for maximizing treatment efficacy and prognosis prediction, and so is microenvironment as a drug resistance mechanism. With classical and new pathological approaches, the book provides a systemic overview of personalized immunotherapies and hyperthermic intraperitoneal chemotherapy, followed by new emerging fields of hereditary cancer, thereby equipping readers to eventually contribute in developing more advanced tools and therapies for curing cancer.



From A Broad Pan Cancer Analysis Towards Personalized Therapy


From A Broad Pan Cancer Analysis Towards Personalized Therapy
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Author :
language : en
Publisher:
Release Date : 2025

From A Broad Pan Cancer Analysis Towards Personalized Therapy written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025 with categories.


The number of cancer cases is expected to rise due to longer life expectancy and global population growth. Cancer occurs when cells grow uncontrollably due to genetic mutations, enabling them to spread and evade the immune system. These cells interact with their environment, making the process complex. However, understanding genetic mutations can provide insights into cancer progression. Targeted therapies based on these mutations are sometimes effective, though their impact is often temporary. Genetic targeting has improved treatments for cancers like lung cancer and melanoma. The aim is to identify specific genetic traits in a patient’s cancer and use drugs that target them. A major challenge is overcoming resistance, as genetic differences within tumor cells complicate treatment. Studies suggest cancer cells evolve over time, similar to natural selection, creating a diverse cell population that resists single-treatment approaches. To address this, researchers are exploring drug combinations that target multiple aspects of cancer. Composite mutations, where multiple mutations occur within the same gene, are also a focus, though they are not yet fully understood. These mutations may play a key role in cancer's evolution and treatment resistance. With the rise of big data, machine learning offers the potential to personalize cancer treatment. By combining genetic, environmental, and lifestyle data, a detailed patient “landscape” can be created. This approach could help doctors make more informed treatment decisions. The goal of this thesis was to study cancer genes, their response to treatments, and identify optimal combination therapies that provide the best outcomes and quality of life. In Chapter 2, we analyzed cancer types and found that 5% of patients had composite mutations, which correlated with other mutations in the same chromosomal region.



Advances In Ai Based Tools For Personalized Cancer Diagnosis Prognosis And Treatment


Advances In Ai Based Tools For Personalized Cancer Diagnosis Prognosis And Treatment
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Author : Israel Tojal Da Silva
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-21

Advances In Ai Based Tools For Personalized Cancer Diagnosis Prognosis And Treatment written by Israel Tojal Da Silva and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-21 with Science categories.




Computational Methods For Personalized Cancer Therapy Based On Genomics Data


Computational Methods For Personalized Cancer Therapy Based On Genomics Data
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Author : Magdalena Feldhahn
language : en
Publisher:
Release Date : 2013

Computational Methods For Personalized Cancer Therapy Based On Genomics Data written by Magdalena Feldhahn and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Cancer categories.