Concepts Of Alzheimer Disease
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Concepts Of Alzheimer Disease
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Author : Peter J. Whitehouse
language : en
Publisher: JHU Press
Release Date : 2003-05-27
Concepts Of Alzheimer Disease written by Peter J. Whitehouse and has been published by JHU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-05-27 with Health & Fitness categories.
As the essays in this volume show, conceptualizing dementia has always been a complex process. With contributions from noted professionals in psychiatry, neurology, molecular biology, sociology, history, ethics, and health policy, Concepts of Alzheimer Disease looks at the ways in which Alzheimer disease has been defined in various historical and cultural contexts. The book covers every major development in the field, from the first case described by Alois Alzheimer in 1907 through groundbreaking work on the genetics of the disease. Essays examine not only the prominent role that biomedical and clinical researchers have played in defining Alzheimer disease, but also the ways in which the perspectives of patients, their caregivers, and the broader public have shaped concepts.
New Concepts In Alzheimer S Disease
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Author : M. Briley
language : en
Publisher:
Release Date : 1986
New Concepts In Alzheimer S Disease written by M. Briley and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Alzheimer's disease categories.
Alzheimer S Disease
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Author : Robert J. Dillmann
language : en
Publisher:
Release Date : 1990
Alzheimer S Disease written by Robert J. Dillmann and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Alzheimer's disease categories.
Alzheimer S Disease
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Author : Harald Hampel
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2012
Alzheimer S Disease written by Harald Hampel and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
How current biomarkers are modernizing the diagnosis of Alzheimer's disease Expanding knowledge on genetic and epigenetic risk factors is rapidly enhancing our understanding of the complex molecular interactions and systems involved in the pathogenesis of Alzheimer's disease. In this publication, leading experts discuss emerging novel conceptual models of the disease along with advances in the development of surrogate markers that will not only improve the accuracy of diagnostic technologies but also improve the prospects of developing disease-modifying interventions. The novel framework of the disease presented here highlights research on biological markers as well as efforts to validate technologies for early and accurate detection. It also introduces notion of a complex systems dysfunction that extends beyond prevailing ideas derived from the amyloid' or tau' hypotheses. This outstanding publication provides researchers, clinicians, students and other professionals interested in neurodegenerative disorders with a comprehensive update on current trends and future directions in therapy development, with special focus on advances in clinical trial designs.
Alzheimer S Disease Pathogenesis
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Author : Suzanne De La Monte
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-09-12
Alzheimer S Disease Pathogenesis written by Suzanne De La Monte and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-12 with Medical categories.
Alzheimer's Disease Pathogenesis: Core Concepts, Shifting Paradigms, and Therapeutic Targets, delivers the concepts embodied within its title. This exciting book presents the full array of theories about the causes of Alzheimer's, including fresh concepts that have gained ground among both professionals and the lay public. Acknowledged experts provide highly informative yet critical reviews of the factors that most likely contribute to Alzheimer's, including genetics, metabolic deficiencies, oxidative stress, and possibly environmental exposures. Evidence that Alzheimer's resembles a brain form of diabetes is discussed from different perspectives, ranging from disease mechanisms to therapeutics. This book is further energized by discussions of how neurotransmitter deficits, neuro-inflammation, and oxidative stress impair neuronal plasticity and contribute to Alzheimer's neurodegeneration. The diversity of topics presented in just the right depth will interest clinicians and researchers alike. This book inspires confidence that effective treatments could be developed based upon the expanding list of potential therapeutic targets.
Alzheimer S Turning Point
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Author : Jack C. de la Torre
language : en
Publisher: Springer
Release Date : 2016-06-25
Alzheimer S Turning Point written by Jack C. de la Torre and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-25 with Medical categories.
This compelling text provides an overview of the available technology for early detection and therapeutic management of vascular risk factors to Alzheimer’s before severe cognitive impairment symptoms appear. Chapters bring the reader from the trackless clinical research that has characterized Alzheimer’s progress for the last 20 years, to a nexus of new ideas and concepts that can change our outlook of this dementia. In-depth examinations of various hypotheses, preventive measures, current and prospective treatments are openly and clearly explored. The author discusses in depth his proposal of the vascular hypothesis of Alzheimer's disease which has become a mother-lode for basic and clinical studies and a key approach to the prevention of this dementia.Alzheimer’s Turning Point offers professionals, students and those looking to learn more about this disorder a fresh clinical perspective of this devastating disease.
Ageing And Dementia
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Author : Kurt Jellinger
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-28
Ageing And Dementia written by Kurt Jellinger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-28 with Medical categories.
Epidemiological studies, modern clinical, neuroimaging, neuropsychological, molecular biological, and genetic studies have considerably enhanced our knowledge about ageing processes of the human brain, its sequelae, diagnostic, and therapeutic possibilities and limits. In addition to Alzheimer's disease and other degenerative dementias, the impact of cerebrovascular lesions and their risk factors in the pathogenesis of cognitive disorders of the aged are increasingly acknowledged, and the recognition of mild cognitive impairment as a frequent initial stage of developing dementia is becoming an increasingly important diagnostic and therapeutic problem. The included papers were presented at the 7th International Symposium in Graz, Sept. 2001 and give a timely overview of the current and future concepts of pathogenesis, diagnosis, and treatment strategies of pathological brain ageing and dementias, early recognition of mild cognitive impairment and future possiblities of prevention of dementing processes.
Alzheimer S Disease
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Author : Amy Borenstein
language : en
Publisher: Academic Press
Release Date : 2016-02-16
Alzheimer S Disease written by Amy Borenstein and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-16 with Psychology categories.
Alzheimer's Disease: Lifecourse Perspectives on Risk Reduction summarizes the growing body of knowledge on the distribution and causes of Alzheimer’s disease (AD) in human populations, providing the reader with knowledge on how we define the disease and what its risk and protective factors are in the context of a life-course approach. At the conclusion of the book, the reader will understand why Alzheimer’s disease likely begins at conception, then progresses through early-life and adult risk factors that ultimately impact the balance between pathologic insults in the brain and the ability of the brain to modify disease symptoms. In contrast to edited volumes that may have little cohesion, this book focuses on an integrated life-course approach to the epidemiology of dementia, in particular, Alzheimer’s disease. Reviews the current science surrounding Alzheimer’s disease Provides a primer of foundational knowledge on the disease's epidemiology and biostatistics Utilizes a life-course approach, providing a novel and integrated view of the evolution of this illness from genes to brain reserve Uses the ‘threshold model’—a theory first described by Dr. Mortimer and widely accepted today—which incorporates the idea of risk factors for the pathology and expression of the disease Proposes that improving brain health through modifiable behaviors can delay disease onset until a later age Examines the future of prevention of Alzheimer’s disease, a subject of great current interest
Self Senility And Alzheimer S Disease In Modern America
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Author : Jesse F. Ballenger
language : en
Publisher: JHU Press
Release Date : 2006-03-31
Self Senility And Alzheimer S Disease In Modern America written by Jesse F. Ballenger and has been published by JHU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-31 with Family & Relationships categories.
Ballenger's work contributes to our understanding of the emergence and significance of dementia as a major health issue.
Mild Cognitive Impairment
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Author : Ronald C. Petersen
language : en
Publisher: Oxford University Press
Release Date : 2003-01-09
Mild Cognitive Impairment written by Ronald C. Petersen and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-09 with Medical categories.
What are the boundary zones between normal aging and Alzheimer's disease (AD)? Are many elderly people whom we regard as normal actually in the early stages of AD? Alzheimer's disease does not develop overnight; the early phases may last for years or even decades. Recently, clinical investigators have identified a transitional condition between normal aging and and very early Alzheimer's disease that they have called mild cognitive impairment, or MCI. This term typically refers to memory impairment beyond what one would expect in individuals of a given age whose other abilities to function in daily life are well preserved. Persons who meet the criteria for mild cognitive impairment have an increased risk of progressing to Alzheimer's disease in the near future. Though many questions about this condition and its underlying neuropathology remain open, full clinical trials are currently underway worldwide aimed at preventing the progression from MCI to Alzheimer's disease. This book addresses the spectrum of issues involved in mild cognitive impairment, and includes chapters on clinical studies, neuropsychology, neuroimaging, neuropathology, biological markers, diagnostic approaches, and treatment. It is intended for clinicians, researchers, and students interested in aging and cognition, among them neurologists, psychiatrists, geriatricians, clinical psychologists, and neuropsychologists.