Contextualizing Systems Biology
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Contextualizing Systems Biology
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Author : Martin Döring
language : en
Publisher: Springer
Release Date : 2015-12-18
Contextualizing Systems Biology written by Martin Döring and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-18 with Science categories.
This collective monograph aims at contributing to an improved understanding of the epistemic presumptions, sociocultural implications and historically backgrounds of the newly emerging and currently expanding approach of systems biology. In doing so, it offers empirically grounded, valuable and reflexive information about a paradigmatic shift in the biosciences for a wide range of scientists working in the interdisciplinary areas of systems biology, synthetic biology, molecular biology, biology, the philosophy of science, the sociology of science and scientific knowledge, science and technology studies, technology assessment and the like. The authors of this monograph share the theoretical methodological premise that science is a culturally and socially embedded practice which characterizes our culture as a scientific one and at the same time draws its innovative potential from its socio-cultural context. This dialectic relationship lies at the heart of the current development of systems biology which is conceived as a so-called successor of ‘-omics’ research and triggered by high-throughput information technologies. At the same time a need for a holistic conceptualization of complex biological processes emerges. The title Contextualizing Systems Biology suggests that this book analyzes the development and advent of systems biology from different theoretical and methodological perspectives. We investigate a variety of contexts ranging from the analysis of cognitive contexts (such as basic theoretical concepts) to regulative contexts (policies) to the concrete application of a systems biology in the socio-scientific context of a European research project. In empirically analyzing these different and interrelated layers and dimensions of systems biology, the scope of the book goes beyond present attempts to investigate the advent of new approaches in the biological sciences as it frames and assesses systems biology from an interdisciplinary and integrated perspective.
Integration Of Omics Approaches And Systems Biology For Clinical Applications
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Author : Antonia Vlahou
language : en
Publisher: John Wiley & Sons
Release Date : 2018-01-24
Integration Of Omics Approaches And Systems Biology For Clinical Applications written by Antonia Vlahou and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-24 with Science categories.
Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape of diseases. The relevance of each approach to the clinical setting is explained and future applications for patient monitoring or treatment are discussed. Integration of omics Approaches and Systems Biology for Clinical Applications presents an overview of state of the art omics techniques. These methods are employed in order to obtain the comprehensive molecular profile of biological specimens. In addition, computational tools are used for organizing and integrating these multi-source data towards developing molecular models that reflect the pathophysiology of diseases. Investigation of chronic kidney disease (CKD) and bladder cancer are used as test cases. These represent multi-factorial, highly heterogeneous diseases, and are among the most significant health issues in developed countries with a rapidly aging population. The book presents novel insights on CKD and bladder cancer obtained by omics data integration as an example of the application of systems biology in the clinical setting. Describes a range of state of the art omics analytical platforms Covers all aspects of the systems biology approach—from sample preparation to data integration and bioinformatics analysis Contains specific examples of omics methods applied in the investigation of human diseases (Chronic Kidney Disease, Bladder Cancer) Integration of omics Approaches and Systems Biology for Clinical Applications will appeal to a wide spectrum of scientists including biologists, biotechnologists, biochemists, biophysicists, and bioinformaticians working on the different molecular platforms. It is also an excellent text for students interested in these fields.
An Introduction To Computational Systems Biology
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Author : Karthik Raman
language : en
Publisher: CRC Press
Release Date : 2021-05-30
An Introduction To Computational Systems Biology written by Karthik Raman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-30 with Computers categories.
This book delivers a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks—a fundamental aspect of computational systems biology. The book covers key modelling paradigms in detail, while at the same time retaining a simplicity that will appeal to those from less quantitative fields. Key Features: A hands-on approach to modelling Covers a broad spectrum of modelling, from static networks to dynamic models and constraint-based models Thoughtful exercises to test and enable understanding of concepts State-of-the-art chapters on exciting new developments, like community modelling and biological circuit design Emphasis on coding and software tools for systems biology Companion website featuring lecture videos, figure slides, codes, supplementary exercises, further reading, and appendices: https://ramanlab.github.io/SysBioBook/ An Introduction to Computational Systems Biology: Systems-Level Modelling of Cellular Networks is highly multi-disciplinary and will appeal to biologists, engineers, computer scientists, mathematicians and others.
Contextualizing The Faith
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Author : A. Scott Moreau
language : en
Publisher: Baker Academic
Release Date : 2018-11-06
Contextualizing The Faith written by A. Scott Moreau and has been published by Baker Academic this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-06 with Religion categories.
This major statement by a leading missiologist represents a lifetime of wrestling with a topic every cross-cultural leader must address: how to adapt the universal gospel to particular settings. This comprehensive yet accessible textbook organizes contextualization, which includes "everything the church is and does," into seven dimensions. Filled with examples, case studies, and diagrams and conversant with contemporary arguments and debates, it offers the author's unique take on the challenge of adapting the faith in local cultures.
Computational Methods In Systems Biology
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Author : Jérôme Feret
language : en
Publisher: Springer
Release Date : 2017-09-18
Computational Methods In Systems Biology written by Jérôme Feret and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-18 with Computers categories.
This book constitutes the refereed proceedings of the 15th International Conference on Computational Methods in Systems Biology, CMSB 2017, held in Darmstadt, Germany, in September 2017. The 15 full papers, 4 tool papers and 4 posters presented together with 1 invited talk were carefully reviewed and selected from 41 regular paper submissions. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verication, validation, analysis, and simulation of biological systems; high-performance computational systems biology and parallel implementations; model inference from experimental data; model integration from biological databases; multi-scale modeling and analysis methods; and computational approaches for synthetic biology.
Medical And Biological Physics
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Author : Prof. Dr. Bilal Semih Bozdemir
language : en
Publisher: Prof. Dr. Bilal Semih Bozdemir
Release Date :
Medical And Biological Physics written by Prof. Dr. Bilal Semih Bozdemir and has been published by Prof. Dr. Bilal Semih Bozdemir this book supported file pdf, txt, epub, kindle and other format this book has been release on with Science categories.
Medical and Biological Physics Introduction to Medical and Biological Physics Fundamentals of Biological Systems Biomechanics and Biophysics Bioelectromagnetism and Bioelectricity Radiation Physics in Medicine Imaging Techniques in Biology and Medicine Spectroscopic Methods in Biological and Medical Research Molecular and Cellular Biophysics Bioinformatics and Computational Biology Tissue Engineering and Regenerative Medicine Nanotechnology in Biology and Medicine Ultrasound and its Applications in Medicine Magnetic Resonance Imaging (MRI) Principles and Techniques Emerging Trends and Future Directions in Medical and Biological Physics
Systems Biology
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Author : Isidore Rigoutsos
language : en
Publisher: Oxford University Press
Release Date : 2006-09-14
Systems Biology written by Isidore Rigoutsos and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-14 with Science categories.
The advent of genome sequencing and associated technologies has transformed biologists' ability to measure important classes of molecules and their interactions. This expanded cellular view has opened the field to thousands of interactions that previously were outside the researchers' reach. The processing and interpretation of these new vast quantities of interconnected data call for sophisticated mathematical models and computational methods. Systems biology meets this need by combining genomic knowledge with theoretical, experimental and computational approaches from a number of traditional scientific disciplines to create a mechanistic explanation of cellular systems and processes. Systems Biology I: Genomics and Systems Biology II: Networks, Models, and Applications offer a much-needed study of genomic principles and their associated networks and models. Written for a wide audience, each volume presents a timely compendium of essential information that is necessary for a comprehensive study of the subject. The chapters in the two volumes reflect the hierarchical nature of systems biology. Chapter authors-world-recognized experts in their fields-provide authoritative discussions on a wide range of topics along this hierarchy. Volume I explores issues pertaining to genomics that range from prebiotic chemistry to noncoding RNAs. Volume II covers an equally wide spectrum, from mass spectrometry to embryonic stem cells. The two volumes are meant to provide a reliable reference for students and researchers alike.
Contextualizing Critical Race Theory On Inclusive Education From A Scholar Practitioner Perspective
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Author : Jose W. Lalas
language : en
Publisher: Emerald Group Publishing
Release Date : 2023-12-12
Contextualizing Critical Race Theory On Inclusive Education From A Scholar Practitioner Perspective written by Jose W. Lalas and has been published by Emerald Group Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-12 with Education categories.
Race does not only resonate with the dichotomy of blackness and whiteness but also on its impact on non-physical attributes, this includes factors such as indigenous status, social class, religion, language, ethnicity, class, gender, sexuality and immigration. The intersection of these factors are key considerations on inclusive education.
Modeling And Simulation Support For System Of Systems Engineering Applications
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Author : Larry B. Rainey
language : en
Publisher: John Wiley & Sons
Release Date : 2015-02-09
Modeling And Simulation Support For System Of Systems Engineering Applications written by Larry B. Rainey and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-09 with Mathematics categories.
“...a much-needed handbook with contributions from well-chosen practitioners. A primary accomplishment is to provide guidance for those involved in modeling and simulation in support of Systems of Systems development, more particularly guidance that draws on well-conceived academic research to define concepts and terms, that identifies primary challenges for developers, and that suggests fruitful approaches grounded in theory and successful examples.” Paul Davis, The RAND Corporation Modeling and Simulation Support for System of Systems Engineering Applications provides a comprehensive overview of the underlying theory, methods, and solutions in modeling and simulation support for system of systems engineering. Highlighting plentiful multidisciplinary applications of modeling and simulation, the book uniquely addresses the criteria and challenges found within the field. Beginning with a foundation of concepts, terms, and categories, a theoretical and generalized approach to system of systems engineering is introduced, and real-world applications via case studies and examples are presented. A unified approach is maintained in an effort to understand the complexity of a single system as well as the context among other proximate systems. In addition, the book features: Cutting edge coverage of modeling and simulation within the field of system of systems, including transportation, system health management, space mission analysis, systems engineering methodology, and energy State-of-the-art advances within multiple domains to instantiate theoretic insights, applicable methods, and lessons learned from real-world applications of modeling and simulation The challenges of system of systems engineering using a systematic and holistic approach Key concepts, terms, and activities to provide a comprehensive, unified, and concise representation of the field A collection of chapters written by over 40 recognized international experts from academia, government, and industry A research agenda derived from the contribution of experts that guides scholars and researchers towards open questions Modeling and Simulation Support for System of Systems Engineering Applications is an ideal reference and resource for academics and practitioners in operations research, engineering, statistics, mathematics, modeling and simulation, and computer science. The book is also an excellent course book for graduate and PhD-level courses in modeling and simulation, engineering, and computer science.
Essaying Metacommunication A Survey And Contextualization Of Communication Research
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Author : Margaret Ruth Zabor
language : en
Publisher: Margaret Ruth Zabor
Release Date : 1978
Essaying Metacommunication A Survey And Contextualization Of Communication Research written by Margaret Ruth Zabor and has been published by Margaret Ruth Zabor this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Social Science categories.
Unpublished doctoral dissertation, Indiana University, Bloomington IN, February 1978