Continuous Flow Chemistry In The Research Laboratory
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Continuous Flow Chemistry In The Research Laboratory
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Author : Toma Glasnov
language : en
Publisher: Springer
Release Date : 2016-06-01
Continuous Flow Chemistry In The Research Laboratory written by Toma Glasnov and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-01 with Science categories.
This book presents a short introduction to the historical background to the field, the state of the art and a brief survey of the available instrumentation and the processing techniques used. The following major areas of interest in synthetic, organic and medicinal chemistry are elaborated on: transition-metal catalyzed reactions, organocatalytic transformations, heterocyclic synthesis, and photochemical reactions. Finally, selected applications in industry are also discussed. With its ample presentation of examples from recent literature, this is an essential and reliable source of information for both experienced researchers and postgraduate newcomers to the field.
Sustainable Flow Chemistry
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Author : Luigi Vaccaro
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-14
Sustainable Flow Chemistry written by Luigi Vaccaro and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-14 with Science categories.
This ready reference not only presents the hot and emerging topic of modern flow chemistry, it is also unique in illustrating the important connection to sustainable chemistry. Focusing on more sustainable methods and applications, the text extensively covers every important field from reaction time optimization to waste minimization, and from safety improvements to microwave applications. In addition, green metrics are presented as a key aspect of the book, helping readers to evaluate the efficiency of flow technologies and their impact on the overall efficiency of a chemical process. An invaluable handbook for every chemist working in the laboratory, whether in academia or industry.
Flow Chemistry In Drug Discovery
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Author : Jesus Alcazar
language : en
Publisher: Springer Nature
Release Date : 2021-12-08
Flow Chemistry In Drug Discovery written by Jesus Alcazar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-08 with Science categories.
This book reviews the challenges and opportunities posed by flow chemistry in drug discovery, and offers a handy reference tool for medicinal chemists interested in the synthesis of biologically active compounds. Prepared by expert contributors, the respective chapters cover not only fundamental methodologies and reactions, such as the application of catalysis, especially biocatalysis and organocatalysis; and non-conventional activation techniques, from photochemistry to electrochemistry; but also the development of new process windows, processes and reactions in drug synthesis. Particular attention is given to automatization and library synthesis, which are of great importance in the pharmaceutical industry. Readers will also find coverage on selected topics of general interest, such as how flow chemistry is contributing to drug discovery R&D in developing countries, and the green character of this enabling technology, for example in the production of raw materials for the pharmaceutical industry from waste. Given its scope, the book appeals to medicinal chemistry researchers working in academia and industry alike, as well as professionals involved in scale-up and drug development.
Accounts On Sustainable Flow Chemistry
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Author : Timothy Noël
language : en
Publisher: Springer Nature
Release Date : 2020-01-23
Accounts On Sustainable Flow Chemistry written by Timothy Noël and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-23 with Science categories.
The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
Flow Chemistry Fundamentals
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Author : Ferenc Darvas
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2021-10-25
Flow Chemistry Fundamentals written by Ferenc Darvas and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-25 with Technology & Engineering categories.
The fully up-dated edition of the two-volume work covers both the theoretical foundation as well as the practical aspects. Presenting the complete insight into driving a chemical reaction provides a deep understanding for new potential technologies. Updated overview on devices and new key concepts of experimental procedures. Vol. 2: Applications.
Flow Chemistry Applications
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Author : Ferenc Darvas
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2014-11-18
Flow Chemistry Applications written by Ferenc Darvas and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-18 with Technology & Engineering categories.
"Flow Chemistry fills the gap in graduate education by covering chemistry and reaction principles along with current practice, including examples of relevant commercial reaction, separation, automation, and analytical equipment. The Editors of Flow Chemistry are commended for having taken the initiative to bring together experts from the field to provide a comprehensive treatment of fundamental and practical considerations underlying flow chemistry. It promises to become a useful study text and as well as reference for the graduate students and practitioners of flow chemistry." Professor Klavs Jensen Massachusetts Institute of Technology, USA Broader theoretical insight in driving a chemical reaction automatically opens the window towards new technologies particularly to flow chemistry. This emerging concept promotes the transformation of present day's organic processes into a more rapid continuous set of synthesis operations, more compatible with the envisioned sustainable world. These two volumes Fundamentals and Applications provide both the theoretical foundation as well as the practical aspects.
Flow Chemistry Fundamentals
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Author : Ferenc Darvas
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2021-10-25
Flow Chemistry Fundamentals written by Ferenc Darvas and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-25 with Technology & Engineering categories.
The fully up-dated edition of the two-volume work covers both the theoretical foundation as well as the practical aspects. Presenting the complete insight into driving a chemical reaction provides a deep understanding for new potential technologies. Updated overview on devices and new key concepts of experimental procedures. Vol. 2: Applications.
Continuous Flow Analysis
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Author : William B. Furman
language : en
Publisher: CRC Press
Release Date : 2020-09-25
Continuous Flow Analysis written by William B. Furman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-25 with Science categories.
In the literature of continuous flow analysis, there are hundreds of descriptions of problems encountered with the various AutoAnalyzer modules. This volume presents the way these have been used in conjunction with chromatographic separations and manufacturing plant process monitoring systems.
Organometallic Chemistry In Industry
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Author : Thomas J. Colacot
language : en
Publisher: John Wiley & Sons
Release Date : 2020-02-11
Organometallic Chemistry In Industry written by Thomas J. Colacot and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-11 with Science categories.
Showcases the important role of organometallic chemistry in industrial applications and includes practical examples and case studies This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R&D researchers as well as Ph.D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions. Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates. The book also examines aspects of homogeneous hydrogenation from industrial research; the latest industrial uses of olefin metathesis; and more. -Includes rare industrial case studies difficult to find in current literature -Helps readers successfully carry out their own reactions -Covers topics like flow chemistry, cross-coupling reactions, and dehydrative decarbonylation -Features a foreword by Nobel Laureate R. H. Grubbs -A perfect resource for every R&D researcher in industry -Useful for PhD students and postdocs: excellent preparation for a job interview Organometallic Chemistry in Industry: A Practical Approach is an excellent resource for all chemists, including those working in the pharmaceutical industry and organometallics.
Organophosphorus Chemistry 2018
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Author : György Keglevich
language : en
Publisher: MDPI
Release Date : 2020-03-05
Organophosphorus Chemistry 2018 written by György Keglevich and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-05 with Science categories.
Organophosphorus chemistry is an important discipline within organic chemistry. Phosphorus compounds, such as phosphines, trialkyl phosphites, phosphine oxides (chalcogenides), phosphonates, phosphinates and >P(O)H species, etc., may be important starting materials or intermediates in syntheses. Let us mention the Wittig reaction and the related transformations, the Arbuzov- and the Pudovik reactions, the Kabachnik–Fields condensation, the Hirao reaction, the Mitsunobu reaction, etc. Other reactions, e.g., homogeneous catalytic transformations or C-C coupling reactions involve P-ligands in transition metal (Pt, Pd, etc.) complex catalysts. The synthesis of chiral organophosphorus compounds means a continuous challenge. Methods have been elaborated for the resolution of tertiary phosphine oxides and for stereoselective organophosphorus transformations. P-heterocyclic compounds, including aromatic and bridged derivatives, P-functionalized macrocycles, dendrimers and low coordinated P-fragments, are also of interest. An important segment of organophosphorus chemistry is the pool of biologically-active compounds that are searched and used as drugs, or as plant-protecting agents. The natural analogue of P-compounds may also be mentioned. Many new phosphine oxides, phosphinates, phosphonates and phosphoric esters have been described, which may find application on a broad scale. Phase transfer catalysis, ionic liquids and detergents also have connections to phosphorus chemistry. Green chemical aspects of organophosphorus chemistry (e.g., microwave-assisted syntheses, solvent-free accomplishments, optimizations, and atom-efficient syntheses) represent a dynamically developing field. Last, but not least, theoretical approaches and computational chemistry are also a strong sub-discipline within organophosphorus chemistry.