Organometallic Chemistry In Industry

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Organometallic Chemistry In Industry

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Author : Thomas J. Colacot
language : en
Publisher: John Wiley & Sons
Release Date : 2020-05-26

Organometallic Chemistry In Industry written by Thomas J. Colacot and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-26 with Science categories.

Showcases the important role of organometallic chemistry in industrial applications and includes practical examples and case studies This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R&D researchers as well as Ph.D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions. Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates. The book also examines aspects of homogeneous hydrogenation from industrial research; the latest industrial uses of olefin metathesis; and more. -Includes rare industrial case studies difficult to find in current literature -Helps readers successfully carry out their own reactions -Covers topics like flow chemistry, cross-coupling reactions, and dehydrative decarbonylation -Features a foreword by Nobel Laureate R. H. Grubbs -A perfect resource for every R&D researcher in industry -Useful for PhD students and postdocs: excellent preparation for a job interview Organometallic Chemistry in Industry: A Practical Approach is an excellent resource for all chemists, including those working in the pharmaceutical industry and organometallics.

Organometallics As Catalysts In The Fine Chemical Industry

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Author : Matthias Beller
language : en
Publisher: Springer
Release Date : 2012-08-31

Organometallics As Catalysts In The Fine Chemical Industry written by Matthias Beller and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-31 with Science categories.

Johannes G. de Vries: Pd-catalyzed coupling reactions.- Gregory T. Whiteker and Christopher J. Cobley: Applications of Rhodium-Catalyzed Hydroformylation in the Pharmaceutical, Agrochemical and Fragrance Industries.- Philippe Dupau: Ruthenium-catalyzed Selective Hydrogenation for Flavor and Fragrance Applications.- Hans-Ulrich Blaser, Benoît Pugin and Felix Spindler: Asymmetric Hydrogenation.- Ioannis Houpis: Case Study: Sequential Pd-catalyzed Cross-Coupling Reactions; Challenges on Scale-up.- Adriano F. Indolese: Pilot Plant Scale Synthesis of an Aryl-Indole - Scale up of a Suzuki Coupling.- Per Ryberg: Development of a Mild and Robust Method for Palladium Catalysed Cyanation on Large Scale.- Cheng-yi Chen: Application of Ring Closing Metathesis Strategy to the Synthesis of Vaniprevir (MK-7009), a 20-Membered Macrocyclic HCV Protease Inhibitor.

Organometallics In Process Chemistry

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Author : Ahmed F. Abdel-Magid
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-06-15

Organometallics In Process Chemistry written by Ahmed F. Abdel-Magid and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-06-15 with Science categories.

The design of efficient syntheses of medicinal agents is one of the prime goals of the process chemist in the pharmaceutical industry. The expanding list of metal-mediated reactions has had a major impact on this endeavor over the last two decades. This volume will highlight some of the areas of organometallic chemistry that have played a particularly important role in development. The chapters are written by chemists who work in the process groups of major pharmaceutical companies and fine chemical manufacturers. Having demonstrated the power of organometallics in their processes the authors herein expand upon their experiences with examples from the literature as reported by process groups within the industry. The chapters are organized either by the application of a particular metal or reaction class. Removal of the residual metal(s) from the isolated active pharmaceutical ingredient (API) is key to the release of the material for human consumption, and hence, is reviewed here as well. This volume of Topics in Organometallic Chemistry is presented to offer a representative cross section of organometallic applications in the pharmaceutical industry as well as to give an appreciation for the creativity possible in process chemistry.

Aqueous Phase Organometallic Catalysis

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Author : Boy Cornils
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-06

Aqueous Phase Organometallic Catalysis written by Boy Cornils and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Science categories.

Now in its second completely revised and expanded edition. Written by the renowned editors B. Cornils and W. A. Herrmann, this book presents every important aspect of aqueous-phase organometallic catalysis, a method which saves time, waste and money. The large-scale application of this "green" technology in chemical industry clearly underlines its practical use outside of academia. New chapters (for example "Organic Chemistry in Water"), 20% more content and fully updated contributions from a plethora of international authors make this book a "must-have" for everyone working in this field. From the reviews of the first edition: "This overview will be extremely useful for everyone active in this field [...]" Angewandte Chemie "This book is an essential in any chemical research library and I strongly recommend it to all synthetic research and teaching chemists. [...]" The Alchemist "The editors are to be congratulated on assembling such a wide range of contributors who have described the industrial as well as the academic aspects of the subject." [...] Journal of Organometallic Chemistry

Organometallic Chemistry And Catalysis

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Author : Didier Astruc
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-14

Organometallic Chemistry And Catalysis written by Didier Astruc and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-14 with Science categories.

This volume covers both basic and advanced aspects of organometallic chemistry of all metals and catalysis. In order to present a comprehensive view of the subject, it provides broad coverage of organometallic chemistry itself. The catalysis section includes the challenging activation and fictionalization of the main classes of hydrocarbons and the industrially crucial heterogeneous catalysis. Summaries and exercises are provides at the end of each chapter, and the answers to these exercises can be found at the back of the book. Beginners in inorganic, organic and organometallic chemistry, as well as advanced scholars and chemists from academia and industry will find much value in this title.

Fundamentals Of Organometallic Catalysis

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Author : Dirk Steinborn
language : en
Publisher: John Wiley & Sons
Release Date : 2011-11-30

Fundamentals Of Organometallic Catalysis written by Dirk Steinborn and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-30 with Technology & Engineering categories.

Vor allem an Studenten fortgeschrittener Semester und Doktoranden gerichtet ist dieses Lehrbuch der Katalyse mit metallorganischen Verbindungen, das auch biologisch relevanten Reaktionen viel Platz einräumt. Hervorragend zum Selbststudium geeignet - mit zahlreichen Übungsaufgaben, nach Schwierigkeitsgraden geordnet und durch Lösungen ergänzt.

Organotransition Metal Chemistry

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Author : Anthony F. Hill
language : en
Publisher: Royal Society of Chemistry
Release Date : 2002

Organotransition Metal Chemistry written by Anthony F. Hill and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Education categories.

What do a pharmaceutical, polymer and solid state chemist have in common? Organometallic chemistry of course, since progress in their diverse fields has at many times relied on this. It is a discipline which stands at the crossroads of so many branches of chemistry, with industrial applications ranging from the gram to megatonne scale. This book aims to introduce undergraduates to the utility of organotransition metal chemistry, a discipline of importance to scientists and technologists in a variety of industry sectors. The main focus will be on the reactivity of organometallic compounds of the transition metals, supported by discussion of structure and bonding and their implications. The aim, on completion of the course, is that a student will be equipped to recognize the key classes of organometallic compounds, their methods of characterization, possible synthetic routes and anticipated reactivity. Ideal for the needs of undergraduate chemistry students, Tutorial Chemistry Texts is a major series consisting of short, single topic or modular texts concentrating on the fundamental areas of chemistry taught in undergraduate science courses. Each book provides a concise account of the basic principles underlying a given subject, embodying an independent-learning philosophy and including worked examples.

Metal Catalysis In Industrial Organic Processes

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Author : Gian Paolo Chiusoli
language : en
Publisher: Royal Society of Chemistry
Release Date : 2019-04-05

Metal Catalysis In Industrial Organic Processes written by Gian Paolo Chiusoli and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-05 with Science categories.

Catalysis underpins most modern industrial organic processes. It has become an essential tool in creating a 'greener' chemical industry by replacing more traditional stoichiometric reactions, which have high energy consumption and high waste production, with mild processes which increasingly resemble Nature's enzymes. Metal-Catalysis in Industrial Organic Processes considers the major areas of the field and discusses the logic of using catalysis in industrial processes. The book provides information on oxidation, hydrogenation, carbonylation, C-C bond formation, metathesis and polymerization processes, as well as on the mechanisms involved. In addition two appendices offer a concise treatment of homogeneous and heterogenous catalysis. Numerous exercises referring to problems of catalytic processes, and research perspectives complete the book. This definitive reference source, written by practising experts in the field, provides detailed and up-to-date information on key aspects of metal catalysis.

Organometallics In Process Chemistry

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Author : Thomas J. Colacot
language : en
Publisher: Springer Nature
Release Date : 2020-04-01

Organometallics In Process Chemistry written by Thomas J. Colacot and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-01 with Science categories.

This volume gives an overview of the applications of organometallic chemistry in process chemistry relevant to the current topics in synthetic chemistry. This volume starts with an introduction on the historical development of organometallics in process chemistry and is followed by chapters dealing with the last five years’ development in various organometallic reaction types such as the challenging cross coupling process, construction of 3.1.0 bicycles, pressure and transfer hydrogenations of historically challenging compounds such as esters, utilization of carbon dioxide for making organic compounds by flow process, drug synthesis and metal detection and scavenging in the finished APIs. A chapter by Colacot et.al., is also devoted to the process development and structural understanding of organometallic catalysts with particular emphasis to LnPd(0) catalysts. An academia – industry collaborated chapter on the use of water as a solvent for organometallic processes is included in this book.

Advances In Organometallic Chemistry

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Author : Anthony F. Hill
language : en
Publisher: Academic Press
Release Date : 2011-08-09

Advances In Organometallic Chemistry written by Anthony F. Hill and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-09 with Science categories.

Almost all branches of chemistry and material science now interface with organometallic chemistry--the study of compounds containing carbon-metal bonds. This widely acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field that has expanded enormously since the publication of Volume 1 in 1964. * Fully updated and expanded to reflect recent advances * Illustrated with pertinenet examples from recent literature * Contributions from leading authorities and industry experts