Contrast Agents Ii
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Contrast Agents Ii
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Author : Werner Krause
language : en
Publisher: Springer
Release Date : 2003-07-01
Contrast Agents Ii written by Werner Krause and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-01 with Science categories.
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The Chemistry Of Contrast Agents In Medical Magnetic Resonance Imaging
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Author : Andre S. Merbach
language : en
Publisher: John Wiley & Sons
Release Date : 2013-02-19
The Chemistry Of Contrast Agents In Medical Magnetic Resonance Imaging written by Andre S. Merbach and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-19 with Science categories.
Magnetic Resonance Imaging (MRI) is one of the most important tools in clinical diagnostics and biomedical research. The number of MRI scanners operating around the world is estimated to be approximately 20,000, and the development of contrast agents, currently used in about a third of the 50 million clinical MRI examinations performed every year, has largely contributed to this significant achievement. This completely revised and extended second edition: Includes new chapters on targeted, responsive, PARACEST and nanoparticle MRI contrast agents. Covers the basic chemistries, MR physics and the most important techniques used by chemists in the characterization of MRI agents from every angle from synthesis to safety considerations. Is written for all of those involved in the development and application of contrast agents in MRI. Presented in colour, it provides readers with true representation and easy interpretation of the images. A word from the Authors: Twelve years after the first edition published, we are convinced that the chemistry of MRI agents has a bright future. By assembling all important information on the design principles and functioning of magnetic resonance imaging probes, this book intends to be a useful tool for both experts and newcomers in the field. We hope that it helps inspire further work in order to create more efficient and specific imaging probes that will allow materializing the dream of seeing even deeper and better inside the living organisms. Reviews of the First Edition: "...attempts, for the first time, to review the whole spectrum of involved chemical disciplines in this technique..."—Journal of the American Chemical Society "...well balanced in its scope and attention to detail...a valuable addition to the library of MR scientists..."—NMR in Biomedicine
Multislice Ct
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Author : M.F. Reiser
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Multislice Ct written by M.F. Reiser and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The introduction of multidetector spiral CT into clinical practice is without any doubt one of the most important technical developments in the field of computed tomography in general, and spiral CT in particular, in recent years. Indeed, multislice CT technology, based on the spiral CT technique invented by W. Kalender almost 20 years ago, has opened immense and totally new perspectives for better utilisation of contrast medium during the examination, for optimal multiplanar reconstruction and for increased patient throughput. The potential applications, more specifically in the area of CT angiography of the brain and the heart and vessels, are most interesting and definitely contribute to better patient care as well as to more effi cient utilisation of equipment. These exciting new clinical applications explain the keen desire of radiologists and other clinicians to hear and learn more about the first results obtained with this new equipment in daily clinical practice. This book will satisfy their needs. Professor Maximilian F. Reiser was among the first to install multidetector CT in his department in Munich and to gain experience with this new radiological tool. He was also able to organise a very successful and well attended international meeting on this hot topic as early as z 2000 in Starnberg, Germany.
Contrast Agents Ii
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Author : Werner Krause
language : en
Publisher: Springer
Release Date : 2010-12-04
Contrast Agents Ii written by Werner Krause and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-04 with Science categories.
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Contrast Agents I
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Author : Werner Krause
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-01-22
Contrast Agents I written by Werner Krause and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-01-22 with Medical categories.
Extracellular MRI and X-ray contrast agents are characterized by their phar- cokinetic behaviour.After intravascular injection their plasma-level time curve is characeterized by two phases. The agents are rapidly distributed between plasma and interstitial spaces followed by renal elimination with a terminal half-live of approximatly 1–2 hours. They are excreted via the kidneys in unchanged form by glomerular filtration. Extracellular water-soluble contrast agents to be applied for X-ray imaging were introduced into clinical practice in 1923. Since that time they have proved to be most valuable tools in diagnostics.They contain iodine as the element of choice with a sufficiently high atomic weight difference to organic tissue. As positive contrast agents their attenuation of radiation is higher compared with the attenuation of the surrounding tissue. By this contrast enhancement X-ray diagnostics could be improved dramatically. In 2,4,6-triiodobenzoic acid derivatives iodine is firmly bound. Nowadays diamides of the 2,4,6-triiodo-5-acylamino-isophthalic acid like iopromide (Ultravist, Fig. 1) are used as non-ionic (neutral) X-ray contrast agents in most cases [1].
Contrast Media
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Author : Henrik S. Thomsen
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-02-14
Contrast Media written by Henrik S. Thomsen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-14 with Medical categories.
Two years only after the publication of the ? rst edition of “Contrast media – Safety issues and ESUR guidelines” in our book series Medical Radiology in 2006, it appeared that a second edition was urgently needed. The ? rst edition was indeed an exceptional success with our readership and sold out rapidly, but moreover the safety of MR contrast media urgently required a reappraisal after the publication of a new and dramatic adverse reaction to some of the gadolini- based agents: the so called NSF syndrome. I am very much indebted to Professor Henrik S. Thomsen and his academic colleagues from the ESUR Contrast Medium Safety Committee for accepting the task to prepare a second edition of their remarkable book.Within a record short period of time they have been able to complete this fully revised new volume. It offers to the readers a comprehensive overview of all problems related to the use of contrast media in modern radiology and of our latest knowledge and insights in the mechanisms of adverse reactions related to contrast media. It answers all questions that radiologists and referring physicians are confronted with in their daily practice when they consider the administration of these agents to their patients.
Contrast Media In Radiology
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Author : M. Amiel
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Contrast Media In Radiology written by M. Amiel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Journalists, always very direct and in search of sensation, essentially asked me two questions on the occasion of this workshop: What were the goals of the meeting? With the improvement of diagnosis through the development of image techniques, didn't the contrast media already have their future behind them? Many answers were provided during the course of the workshop, and in order to best answer the journalists I proposed the following synopsis. 1. Since the 1979 Colorado Springs workshop organized by E. Lasser, progress has been so rapid and the newly available works so numerous that another meeting on an international level for the purpose of pre senting and discussing these advances appeared indispensable. Why not then in Europe and why not in Lyon? To expand on this progress, by 1981 the new contrast media with less-hyperosmolar molecules, still in the trial stage in 1979, were al most all available commercially for angiography, albeit at prohibitive prices. The advantages of these various media are becoming better known; moreover, in the wake of Lasser's work, our understanding of the pathophysiology of their noxious effects is also advancing rapidly owing to the use of models (for the target organs: heart, vessel wall, nervous system, kidney; and for the more general reactions: blood cells, coagulation, complement system, circulating enzymatic systems). In addition, further new molecules are currently being studied in re search laboratories. 2.
Advances In Echo Imaging Using Contrast Enhancement
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Author : N.C. Nanda
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Advances In Echo Imaging Using Contrast Enhancement written by N.C. Nanda and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.
This book will familiarize the reader with recent advances in echo imaging technology with special emphasis on echo enhancing agents. Several important strides have been made in this field during the past few years, especially in the contrast enhancement of conventional and color Doppler images. The book begins with chapters on the history of contrast echocardiography, the principles of contrast echo and descriptions of new contrast agents capable of transpulmonary passage following intravenous injection. Safety issues in contrast echocardiography are also discussed. The second section of the book deals with clinical uses of echo contrast agents. Their usefulness in the identification of cardiac structures and assessment of pathological lesions using both transthoracic and transesophageal echocardiography are fully discussed. Technical and practical considerations in the use of various contrast agents are also described. The use of contrast echo in the identification of cardiac sources of embolism as well as possible mechanisms and clinical significance of spontaneous contrast echoes are also covered. Six chapters fully discuss the basics of contrast enhancement of conventional and color Doppler images and its clinical utility in the noninvasive assessment of pulmonary artery pressure, regurgitant and stenotic lesions and in the delineation of coronary arteries. Another chapter describes the non-cardiac applications of the echo contrast enhancement technique. The final section of the book investigates the role of echo contrast enhancement in quantitative cardiovascular analysis.
Mri Contrast Agents
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Author : Sophie Laurent
language : en
Publisher: Springer
Release Date : 2016-11-03
Mri Contrast Agents written by Sophie Laurent and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-03 with Technology & Engineering categories.
This book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc.
Fluorine Magnetic Resonance Imaging
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Author : Ulrich Flogel
language : en
Publisher: CRC Press
Release Date : 2016-10-26
Fluorine Magnetic Resonance Imaging written by Ulrich Flogel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-26 with Medical categories.
Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered significant scientific interest in the biomedical research community owing to the unique properties of fluorinated materials and the 19F nucleus. Fluorine has an intrinsically sensitive nucleus for MRI. There is negligible endogenous 19F in the body and thus there is no background signal. Fluorine-containing compounds are ideal tracer labels for a wide variety of MRI applications. Moreover, the chemical shift and nuclear relaxation rate can be made responsive to physiology via creative molecular design. This book is an interdisciplinary compendium that details cutting-edge science and medical research in the emerging field of 19F MRI. Edited by Ulrich Flögel and Eric Ahrens, two prominent MRI researchers, this book will appeal to investigators involved in MRI, biomedicine, immunology, pharmacology, probe chemistry, and imaging physics.