Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes

DOWNLOAD

Download Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page

Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes

DOWNLOAD
Author : David J. Hill
language : en
Publisher: Bentham Science Publishers
Release Date : 2016-12-02

Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes written by David J. Hill and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-02 with Science categories.

Plasticity in insulin-producing cells (β-cells) of the pancreas is a major contributor to metabolic control. Targeted regeneration of pancreatic β-cells for the reversal of diabetes (by optimizing β-cells mass and proliferation to meet metabolic requirements and counter autoimmune response) is still a theoretical intervention. This monograph reviews the biology, ontogeny, capabilities, and present practical limitations of β-cell plasticity. Relevant biochemical pathways are described with the inclusion of information about how they change with aging, during pregnancy, and with diet. Readers will learn the following key aspects about β-cell plasticity: -current knowledge of pancreatic β-cells development, and how β-cell mass and proliferation change throughout the human lifespan -the mechanisms responsible for β-cell plasticity, based on animal models and clinical studies revealing environmental, epigenetic, endocrine and paracrine regulators -the therapeutic potential of resident stem cells within the pancreas / bone marrow and β-cell progenitors This monograph is essential reading for researchers interested in updated knowledge about the molecular and cellular biology of β-cells in the quest to find a reliable therapy for diabetes.

Current And Future Developments In Physiology Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes

DOWNLOAD
Author : David Hill
language : en
Publisher: Current and Future Development
Release Date : 2016-12-02

Current And Future Developments In Physiology Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes written by David Hill and has been published by Current and Future Development this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-02 with Science categories.

Plasticity in insulin-producing cells (β-cells) of the pancreas is a major contributor to metabolic control. Targeted regeneration of pancreatic β-cells for the reversal of diabetes (by optimizing β-cells mass and proliferation to meet metabolic requirements and counter autoimmune response) is still a theoretical intervention. This monograph reviews the biology, ontogeny, capabilities, and present practical limitations of β-cell plasticity. Relevant biochemical pathways are described with the inclusion of information about how they change with aging, during pregnancy, and with diet. Readers will learn the following key aspects about β-cell plasticity: -current knowledge of pancreatic β-cells development, and how β-cell mass and proliferation change throughout the human lifespan -the mechanisms responsible for β-cell plasticity, based on animal models and clinical studies revealing environmental, epigenetic, endocrine and paracrine regulators -the therapeutic potential of resident stem cells within the pancreas / bone marrow and β-cell progenitors This monograph is essential reading for researchers interested in updated knowledge about the molecular and cellular biology of β-cells in the quest to find a reliable therapy for diabetes.

Pancreatic Beta Cell In Health And Disease

DOWNLOAD
Author : Susumu Seino
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-04-08

Pancreatic Beta Cell In Health And Disease written by Susumu Seino and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-08 with Science categories.

The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis. This book provides a comprehensive review of the beta cell in health and disease. The book’s primary aim is to encourage investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.

Pancreatic Islet Biology

DOWNLOAD
Author : Anandwardhan A. Hardikar
language : en
Publisher: Springer
Release Date : 2016-10-25

Pancreatic Islet Biology written by Anandwardhan A. Hardikar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-25 with Science categories.

This comprehensive volume discusses in vitro laboratory development of insulin-producing cells. It encompasses multiple aspects of islet biology—from embryonic development and stem cell differentiation to clinical studies in islet transplantation, regulation of islet beta-cell regeneration, pancreatic progenitors, mathematical modelling of islet development, epigenetic regulation, and much more. The chapter authors represent leading laboratories from around the world who contribute their international perspectives and global expertise. Collectively, they provide the reader with a concise yet detailed knowledge of processes and current developments in islet regenerative biology. Pancreatic Islet Biology, part of the Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers and clinicians in stem cells or endocrinology, especially those focusing on diabetes.

Fetal And Early Postnatal Programming And Its Influence On Adult Health

DOWNLOAD
Author : Mulchand S. Patel
language : en
Publisher: CRC Press
Release Date : 2017-07-12

Fetal And Early Postnatal Programming And Its Influence On Adult Health written by Mulchand S. Patel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-12 with Medical categories.

There is a documented link between fetal nutrition and the development of disease risk in adult life. Including the early postnatal period, during which a newborn continues to grow rapidly influenced by environmental factors, suggests that individuals are subject to risks for more than just the fetal period. Fetal and Early Postnatal Programming and its Influence on Adult Health focuses on interrelated aspects of cellular programming related to early nutrition and this potential global health problem.

Molecular Basis Of Pancreas Development And Function

DOWNLOAD
Author : Joel F. Habener
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Molecular Basis Of Pancreas Development And Function written by Joel F. Habener and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Diabetes mellitus is rapidly increasing in prevalence throughout both developed and developing countries. The social and economic burden of this disease is estimated to cost 14 billion dollars worldwide. In the USA alone, 15 million individuals are diabetic, nearly half of them unaware of their condition. Complications of diabetes mellitus are the leading causes for blindness, limb amputation and chronic renal failure and kidney transplantation in industrialized countries. Further, diabetes mellitus per se and the metabolic derangement associated with diabetes are important risk factors for cardiovascular disease. Diabetes, as defined by an elevated fasting blood glucose level is presently subdivided in etiologically distinct groups. The most prevalent being type 2 (adult onset) diabetes characterized by insulin resistance and failure of the ~-cell to supply insulin in amounts sufficient to meet the body's needs. Type 1 (juvenile) diabetes, most commonly with an onset during childhood and adolescence, is caused by an auto-immune destruction of the pancreatic ~-cells. The causations of both type 1 and type 2 diabetes involve a combination of complex genetic traits and environmental influences. A third category are the mature onset diabetes of the young (MODY). This comparatively small group of patients (-10% of diabetes) presents relative early in life «30 years of age) compared to the more common late onset type 2 diabetes.

Pathogenesis Of Non Insulin Dependent Diabetes Mellitus

DOWNLOAD
Author : Valdemar Grill
language : en
Publisher:
Release Date : 1988

Pathogenesis Of Non Insulin Dependent Diabetes Mellitus written by Valdemar Grill and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.

Gestational Diabetes During And After Pregnancy

DOWNLOAD
Author : Catherine Kim
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-01-02

Gestational Diabetes During And After Pregnancy written by Catherine Kim and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-02 with Medical categories.

Gestational Diabetes Mellitus is becoming an increasingly prevalent disease as obesity and other chronic diseases are on the rise. It requires careful and informed clinical management as the care received during pregnancy affects not only perinatal health but the risk of developing type 2 diabetes even decades into the future, in both the mother and the child.From epidemiology and pathophysiology to diagnosis and management, covering recent breakthroughs in research and up-to-date developments in clinical practice, Gestational Diabetes During and After Pregnancy offers the reader a comprehensive and current look at Gestational Diabetes. Anyone involved in the research, public health or clinical aspects of Gestational Diabetes will find this volume a valuable aid in consolidating all recent developments regarding this disease.

The Pancreatic Beta Cell

DOWNLOAD
Author :
language : en
Publisher: Academic Press
Release Date : 2014-02-20

The Pancreatic Beta Cell written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-20 with Medical categories.

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. Expertise of the contributors Coverage of a vast array of subjects In depth current information at the molecular to the clinical levels Three-dimensional structures in color Elaborate signaling pathways

The Endocrine Pancreas

DOWNLOAD
Author : Ellis Samols
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1991

The Endocrine Pancreas written by Ellis Samols and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.