Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes

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Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes
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Author : David J. Hill
language : en
Publisher: Bentham Science Publishers
Release Date : 2016-12-02
Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes written by David J. Hill and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-02 with Science categories.
Plasticity in insulin-producing cells (β-cells) of the pancreas is a major contributor to metabolic control. Targeted regeneration of pancreatic β-cells for the reversal of diabetes (by optimizing β-cells mass and proliferation to meet metabolic requirements and counter autoimmune response) is still a theoretical intervention. This monograph reviews the biology, ontogeny, capabilities, and present practical limitations of β-cell plasticity. Relevant biochemical pathways are described with the inclusion of information about how they change with aging, during pregnancy, and with diet. Readers will learn the following key aspects about β-cell plasticity: -current knowledge of pancreatic β-cells development, and how β-cell mass and proliferation change throughout the human lifespan -the mechanisms responsible for β-cell plasticity, based on animal models and clinical studies revealing environmental, epigenetic, endocrine and paracrine regulators -the therapeutic potential of resident stem cells within the pancreas / bone marrow and β-cell progenitors This monograph is essential reading for researchers interested in updated knowledge about the molecular and cellular biology of β-cells in the quest to find a reliable therapy for diabetes.
Fetal And Early Postnatal Programming And Its Influence On Adult Health
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Author : Mulchand S. Patel
language : en
Publisher: CRC Press
Release Date : 2017-07-12
Fetal And Early Postnatal Programming And Its Influence On Adult Health written by Mulchand S. Patel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-12 with Medical categories.
There is a documented link between fetal nutrition and the development of disease risk in adult life. Including the early postnatal period, during which a newborn continues to grow rapidly influenced by environmental factors, suggests that individuals are subject to risks for more than just the fetal period. Fetal and Early Postnatal Programming and its Influence on Adult Health focuses on interrelated aspects of cellular programming related to early nutrition and this potential global health problem.
Pancreatic Beta Cell In Health And Disease
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Author : Susumu Seino
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-04-08
Pancreatic Beta Cell In Health And Disease written by Susumu Seino and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-08 with Science categories.
The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis. This book provides a comprehensive review of the beta cell in health and disease. The book’s primary aim is to encourage investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.
Current And Future Developments In Physiology Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes
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Author : David Hill
language : en
Publisher: Current and Future Development
Release Date : 2016-12-02
Current And Future Developments In Physiology Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes written by David Hill and has been published by Current and Future Development this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-02 with Science categories.
Plasticity in insulin-producing cells (β-cells) of the pancreas is a major contributor to metabolic control. Targeted regeneration of pancreatic β-cells for the reversal of diabetes (by optimizing β-cells mass and proliferation to meet metabolic requirements and counter autoimmune response) is still a theoretical intervention. This monograph reviews the biology, ontogeny, capabilities, and present practical limitations of β-cell plasticity. Relevant biochemical pathways are described with the inclusion of information about how they change with aging, during pregnancy, and with diet. Readers will learn the following key aspects about β-cell plasticity: -current knowledge of pancreatic β-cells development, and how β-cell mass and proliferation change throughout the human lifespan -the mechanisms responsible for β-cell plasticity, based on animal models and clinical studies revealing environmental, epigenetic, endocrine and paracrine regulators -the therapeutic potential of resident stem cells within the pancreas / bone marrow and β-cell progenitors This monograph is essential reading for researchers interested in updated knowledge about the molecular and cellular biology of β-cells in the quest to find a reliable therapy for diabetes.
Control Of Regulatory T Cell Stability Plasticity And Function In Health And Disease
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Author : Margarita Dominguez-Villar
language : en
Publisher: Frontiers Media SA
Release Date : 2021-03-08
Control Of Regulatory T Cell Stability Plasticity And Function In Health And Disease written by Margarita Dominguez-Villar and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-08 with Medical categories.
Glucose Sensing
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Author : Chris D. Geddes
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-12-29
Glucose Sensing written by Chris D. Geddes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-29 with Science categories.
An essential reference for any laboratory working in the analytical fluorescence glucose sensing field. The increasing importance of these techniques is typified in one emerging area by developing non-invasive and continuous approaches for physiological glucose monitoring. This volume incorporates analytical fluorescence-based glucose sensing reviews, specialized enough to be attractive to professional researchers, yet appealing to a wider audience of scientists in related disciplines of fluorescence.
Gestational Diabetes During And After Pregnancy
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Author : Catherine Kim
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-01-02
Gestational Diabetes During And After Pregnancy written by Catherine Kim and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-02 with Medical categories.
Gestational Diabetes Mellitus is becoming an increasingly prevalent disease as obesity and other chronic diseases are on the rise. It requires careful and informed clinical management as the care received during pregnancy affects not only perinatal health but the risk of developing type 2 diabetes even decades into the future, in both the mother and the child.From epidemiology and pathophysiology to diagnosis and management, covering recent breakthroughs in research and up-to-date developments in clinical practice, Gestational Diabetes During and After Pregnancy offers the reader a comprehensive and current look at Gestational Diabetes. Anyone involved in the research, public health or clinical aspects of Gestational Diabetes will find this volume a valuable aid in consolidating all recent developments regarding this disease.
Islets Of Langerhans
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Author : M. S. Islam
language : en
Publisher: Springer
Release Date : 2014-10-29
Islets Of Langerhans written by M. S. Islam and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-29 with Medical categories.
This book contains critical background information, and recent advances made in essentially all areas of islet research. It is a major reference book, the first of its kind, for islet researchers, and diabetes researchers. Anybody, including the experts, and the beginners, interested in the study of islet physiology, and diabetes, will find this book extremely useful. The book is robust in its breadth: it deals with anatomy, histology, ultra-structure, evolution and comparative anatomy, imaging, developmental biology, programming, apoptosis, mitochondrial function, metabolism, cellular signaling, electrophysiology, oscillation of hormone secretion, islets of model animals, immunology, proteomics, regenerative medicine, clinical advances, and islet transplantation. Individual chapters contributed by a large number of experts and enthusiasts, not only provide a balanced view of the recent advances made in the respective fields, but also provide directions and thoughts for future research. Thanks to vivid and colorful illustrations, tables and sketches, the book as a whole, and the individual chapters make reading a pleasant experience. If you are interested in diabetes research, you will love to have a personal copy of this book.
Mechanisms Of Insulin Action
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Author : Alan R. Saltiel
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-05
Mechanisms Of Insulin Action written by Alan R. Saltiel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-05 with Medical categories.
More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. In addition, between 17 and 40 million people have insulin resistance, impaired glucose tolerance, or the cluster of abnormalities referred to variably as the metabolic syndrome, the dysmetabolic syndrome, syndrome X, or the insulin resistance syndrome. In all of these disorders, a central component of the pathophysiology is insulin resistance, i.e., reduced responsiveness to insulin in tissues such as muscle, fat and liver. Insulin resistance is also closely linked to other common health problems, including obesity, polycystic ovarian disease, hyperlipidemia, hypertension, and atherosclerosis. In this book, we will attempt to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. We explore insulin action at the most basic levels, through complex systems. The book will be appealing to basic and clinical scientists.
Diabetes Literature Index
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Author :
language : en
Publisher:
Release Date : 1977
Diabetes Literature Index written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Diabetes categories.