Critical Reviews Oxidative Stress And Aging Advances In Basic Science Diagnostics And Intervention In 2 Vols
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Critical Reviews Of Oxidative Stress And Aging
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Author : Richard G. Cutler
language : en
Publisher: World Scientific
Release Date : 2003
Critical Reviews Of Oxidative Stress And Aging written by Richard G. Cutler and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Family & Relationships categories.
This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.
Oxidative Stress And Age Related Neurodegeneration
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Author : Yuan Luo
language : en
Publisher: CRC Press
Release Date : 2005-11-21
Oxidative Stress And Age Related Neurodegeneration written by Yuan Luo and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-21 with Medical categories.
Oxidative Stress and Age-Related Neurodegeneration brings together researchers from a variety of fields to compare normal aging and disease-related neurodegeneration in terms of susceptibility to and effects of oxidative stress. They address how these effects can be attenuated, and examine whether antioxidants and natural micronutrients, such as those found in Gingko biloba, green tea, blueberries, and grape seed extract, can play a role. The book includes various ways research is getting to the core of neurodegenerative disease, including the use of proteomics, comparisons to related diseases, and examinations at the cellular and molecular levels.
Reactive Oxygen Species Ros Nanoparticles And Endoplasmic Reticulum Er Stress Induced Cell Death Mechanisms
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Author : Loutfy H. Madkour
language : en
Publisher: Academic Press
Release Date : 2020-06-27
Reactive Oxygen Species Ros Nanoparticles And Endoplasmic Reticulum Er Stress Induced Cell Death Mechanisms written by Loutfy H. Madkour and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-27 with Medical categories.
Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS?mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals?induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and oxidative damage mechanisms. It also examines the nanotoxicity, cytotoxicity and genotoxicity mechanisms of nanomaterials and the effects of nanoparticle interactions. Antioxidant defense therapy and strategies for treatment round out the book, making it an ideal resource for researchers and professional scientists in toxicology, environmental chemistry, environmental science, nanomaterials and the pharmaceutical sciences. - Covers the ecotoxicology of environmental heavy metal ions and the interactions between specific heavy metals?induced cell responses and oxidative stress - Provides a better understanding of the mechanism of nanomaterial-induced toxicity as a first defense for hazard prevention - Covers recent advances in new nanomedication technologies for the effects of NPs on oxidative stress, ROS and ER stress - Discusses the effects of interactions between antioxidant defense therapy, ROS and strategies for treatment
Aging Mechanisms
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Author : Nozomu Mori
language : en
Publisher: Springer
Release Date : 2015-11-26
Aging Mechanisms written by Nozomu Mori and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-26 with Medical categories.
This book brings together the most up-to-date information on recent research results of leading laboratories on aging science in East Asia, particularly in Japan, Korea, and Hong Kong. Starting with a comprehensive overview of various hypotheses on biological mechanisms of aging by Dr. Sataro Goto, each chapter covers broad aspects of the most recent findings in aging-related topics: centenarian studies and genome analysis of progeria, metabolic biochemistry and neurobiology, longevity controls in yeast and nematodes, oxidative stress and calorie restriction, and neurodegeneration mechanisms in Alzheimer’s and Huntington’s diseases, with further potential therapeutic approaches to these age-related neurodegenerative diseases. Also included, in part, is a summary and the outcomes of a scientific discussion forum called the Asian Aging Core for Longevity (AACL) that has been held annually alternating between Japan and Korea during the last decade. This book can serve as a useful resource for finding appropriate collaborators in the areas it covers. The target readership is made up of graduate students and researchers at universities, medical and/or life-science schools, and biomedical and pharmaceutical institutes. Why does aging exist? How do we age? How is each organism’s lifespan determined? These are fundamental questions in the field. We may be still far from achieving a complete view of aging mechanisms, but this book, Aging Mechanisms, offers an excellent opportunity to become familiar with the most updated progress in the biomedical research of aging in Japan and Korea, the two leading nations for human longevity.
The Future Of Aging
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Author :
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-08-17
The Future Of Aging written by and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-17 with Medical categories.
Just as the health costs of aging threaten to bankrupt developed countries, this book makes the scientific case that a biological "bailout" could be on the way, and that human aging can be different in the future than it is today. Here 40 authors argue how our improving understanding of the biology of aging and selected technologies should enable the successful use of many different and complementary methods for ameliorating aging, and why such interventions are appropriate based on our current historical, anthropological, philosophical, ethical, evolutionary, and biological context. Challenging concepts are presented together with in-depth reviews and paradigm-breaking proposals that collectively illustrate the potential for changing aging as never before. The proposals extend from today to a future many decades from now in which the control of aging may become effectively complete. Examples include sirtuin-modulating pills, new concepts for attacking cardiovascular disease and cancer, mitochondrial rejuvenation, stem cell therapies and regeneration, tissue reconstruction, telomere maintenance, prevention of immunosenescence, extracellular rejuvenation, artificial DNA repair, and full deployment of nanotechnology. The Future of Aging will make you think about aging differently and is a challenge to all of us to open our eyes to the future therapeutic potential of biogerontology.
Endogenous Toxins 2 Volume Set
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Author : Peter J. O'Brien
language : en
Publisher: John Wiley & Sons
Release Date : 2009-12-02
Endogenous Toxins 2 Volume Set written by Peter J. O'Brien and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-02 with Science categories.
Designed as a first-stop reference for researchers and professionals in toxicology, pharmacology and medicine, this handbook is the very first to tie together the knowledge from many disciplines that has so far been available only from widely dispersed sources in the primary literature. As such, it presents the complete picture on what is currently known about endogenous toxins, including their generation, mode of action, resulting disease condition, and available countermeasures. Clearly divided into four parts, the first systematically covers important toxic molecule species, including metabolic intermediates and reactive oxygen species. The second discusses the role of genetically determined metabolic malfunctions, such as galactosemia, hyperlipidemia, porphyria, hemochromatosis and related conditions, while part three looks at acquired and chronic diseases caused or exacerbated by endogenous toxins, such as hepatic injury, asthma, rheumatism, colorectal cancer, reperfusion diseases, neurodegneration and aging. The final part reviews currents strategies to control and minimize the effect of endogenous toxins, either by nutritional or pharmacological interventions. With its complete coverage integrating molecular and systemic aspects from the biochemical basis to human disease conditions, this comprehensive reference will appeal to a broad target group of toxicologists, biochemists, nutrition specialists and physicians.
Nutrition And Traumatic Brain Injury Tbi
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Author : Wael Mohamed
language : en
Publisher: Springer Nature
Release Date : 2024-12-11
Nutrition And Traumatic Brain Injury Tbi written by Wael Mohamed and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-11 with Medical categories.
The book provides a comprehensive exploration of the relationship between nutrition and traumatic brain injury (TBI). Divided into two sections, the book covers various aspects of TBI, from its biomechanics and pathophysiological changes to evidence-based clinical guidelines and experimental models. Section I covers the background of TBI, including the definition and biomechanics of TBI, an understanding of pathophysiological changes that occur in the brain, and the importance of evidence-based clinical guidelines for effective TBI management. The section also delves into experimental models of TBI and the role of biomarkers in diagnosing and assessing TBI. Furthermore, it explores early feeding guidelines following TBI, emphasizing the significance of nutrition in the recovery process. Section II focuses on the connection between nutrition and TBI. It examines the concept of resilience and nutri-protection against TBI prior to the injury, highlighting strategies to enhance the brain's ability to withstand trauma. The book then explores the role of various nutrients and dietary components in TBI, such as antioxidants, branched-chain amino acids, choline, creatine, ketogenic diet, magnesium, polyunsaturated fatty acids (EPA and DHA), polyphenols, vitamin D, and zinc. Each topic is explored in depth, considering their impact on TBI outcomes and potential therapeutic applications. Furthermore, this section delves into nutritional interventions for TBI management. It addresses the selection of appropriate nutritional interventions and mechanistic targets for effective treatment. The section also explores the integration of nutrition into clinical practice guidelines for TBI and the emerging field of nutrigenomics, which investigates the interaction between nutrition and the genetic factors involved in TBI. Additionally, the section discusses the role of pharmacognosy in TBI research and provides nutritional recommendations for TBI management, considering the diverse needs of individuals affected by TBI. The book contributes to advancing the understanding and management of TBI by exploring the background, highlighting the importance of nutrition, and offering insights into nutritional interventions with potential implications for both preventive and therapeutic approaches. The book is a great resource for students and brain/neuroscience researchers.
Biology Of Aging
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Author : Robert Arking
language : en
Publisher: Oxford University Press
Release Date : 2006-02-02
Biology Of Aging written by Robert Arking and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-02-02 with Family & Relationships categories.
Robert Arking's Biology of Aging is an introductory text to the biology of aging which gives advanced undergraduate and graduate students a thorough review of the entire field. The mass of data related to aging is summarized into fifteen focused chapters, each dealing with some particular aspect of the problem. His prior two editions have also served admirably as a reference text for clinicians and scientists. This new edition captures the extraordinary recent advances in our knowledge of the ultimate and proximal mechanisms underlying the phenomenon of aging.
Antioxidants And Functional Foods For Neurodegenerative Disorders
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Author : Abhai Kumar
language : en
Publisher: CRC Press
Release Date : 2021-01-07
Antioxidants And Functional Foods For Neurodegenerative Disorders written by Abhai Kumar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-07 with Health & Fitness categories.
Neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are a growing problem across the world’s aging population. Oxidative stress in the brain plays a central role in a common pathophysiology of these diseases. This book presents scientific research on the potential of antioxidant therapy in the prevention and treatment of neurodegenerative disorders. This book outlines the roles of oxidative stress and diabetes mellitus in neurodegeneration, describes the molecular mechanisms of neurodegenerative disorders including the roles of environmental pollutants and inflammatory responses, and explores mitochondrial dysfunction. It then describes the protective abilities of antioxidants – including vitamin D, tocotrienol and coenzyme Q10 – against neurodegeneration. The book demonstrates the therapeutic potential of ketogenic diets, and highlights the roles of medicinal plants, phytopharmaceuticals, traditional medicines and food nutrients in neuroprotection. Key Features: Explains damage caused by numerous neurodegenerative disorders and the possible protection offered by antioxidants and functional foods. Describes molecular mechanisms of neurodegeneration by oxidative stress, advancing age, diabetes and mitochondrial dysfunctions. Demonstrates protection offered by nutraceuticals, antioxidants, botanical extracts and functional foods. The book contains twenty-three chapters divided into six sections written by leading researchers. This book is essential reading for health professionals, dietitians, food and nutrition scientists and anyone wanting to improve their knowledge of etiology of neurodegenerative diseases.
Longevity Health Sciences
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Author : Richard G. Cutler
language : en
Publisher:
Release Date : 2005
Longevity Health Sciences written by Richard G. Cutler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Health & Fitness categories.
Presenting an overview of many of the issues discussed in the field of longevity science and medicine, this book aims to explore the links between the basic gerontological research and the practice of longevity medicine. The topics include oxidative stress, genetic/biochemical mechanisms, hormone therapy, nutrition, fitness, and exercise.