Cross Over Experiments

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Cross Over Experiments

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Author : David Ratkowsky
language : en
Publisher: CRC Press
Release Date : 2020-01-29

Cross Over Experiments written by David Ratkowsky and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-29 with Mathematics categories.

Developing a model-based approach that enables any cross-over trial, of any degree of imbalance, to be analyzed both for direct effects and for residual effects, using consistent procedures that employ commercially available statistical software, this text offers a guide to the analysis of cross-over designs.;Illustrating practical applications throughout with examples, this book: emphasizes the importance of choosing highly efficient designs that separate treatment and carryover effects; demonstrates the exact methodology needed to handle the analysis of data; presents a new methodology for the analysis of binary and categorical data; and considers the effects of blocking. The appendices facilitate the choosing of an appropriate design for every experimental need.

A Theoretical And Experimental Study On The Changes In The Crossing Over Value Their Causes And Meaning

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Author : Gerhardus Eloff
language : en
Publisher: Springer
Release Date : 2013-11-22

A Theoretical And Experimental Study On The Changes In The Crossing Over Value Their Causes And Meaning written by Gerhardus Eloff and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-22 with Science categories.

Optimal Crossover Designs

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Author : Aloke Dey
language : en
Publisher: World Scientific
Release Date : 2009

Optimal Crossover Designs written by Aloke Dey and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Science categories.

This monograph presents a comprehensive and up-to-date account of the developments in optimality aspects of crossover designs. Crossover designs are immensely useful in various areas of human investigation including agriculture, animal nutrition, clinical trials, pharmaceutical studies, biological assays, weather modification experiments, sensory evaluation of food products and learning experiments. Research on the optimality aspects of crossover designs has developed only in the last three decades, and it has now emerged as a potential field for further investigation. This book is the first comprehensive treatise on this subject. It covers optimal crossover designs at length by consolidating vast amounts of material from the literature, and includes many recent and deep results. It is expected that this book will not only provide a one-stop reference for the available results, but also encourage further research in this area of substantial practical relevance.

Design And Analysis Of Cross Over Trials Second Edition

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Author : Byron Jones
language : en
Publisher: CRC Press
Release Date : 2003-03-12

Design And Analysis Of Cross Over Trials Second Edition written by Byron Jones and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-12 with Mathematics categories.

The first edition of Design and Analysis of Cross-Over Trials quickly became the standard reference on the subject and has remained so for more than 12 years. In that time, however, the use of cross-over trials has grown rapidly, particularly in the pharmaceutical arena, and researchers have made a number of advances in both the theory and methods applicable to these trials. Completely revised and updated, the long-awaited second edition of this classic text retains its predecessor's careful balance of theory and practice while incorporating new approaches, more data sets, and a broader scope. Enhancements in the second edition include: A new chapter on bioequivalence Recently developed methods for analyzing longitudinal continuous and categorical data Real-world examples using the SAS system A comprehensive catalog of designs, datasets, and SAS programs available on a companion Web site at www.crcpress.com The authors' exposition gives a clear, unified account of the design and analysis of cross-over trials from a statistical perspective along with their methodological underpinnings. With SAS programs and a thorough treatment of design issues, Design and Analysis of Cross-Over Trials, Second Edition sets a new standard for texts in this area and undoubtedly will be of direct practical value for years to come.

Advanced Organic Chemistry

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Author : Reinhard Bruckner
language : en
Publisher: Academic Press
Release Date : 2002

Advanced Organic Chemistry written by Reinhard Bruckner and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Science categories.

A best-selling mechanistic organic chemistry text in Germany, this text's translation into English fills a long-existing need for a modern, thorough and accessible treatment of reaction mechanisms for students of organic chemistry at the advanced undergraduate and graduate level. Knowledge of reaction mechanisms is essential to all applied areas of organic chemistry; this text fulfills that need by presenting the right material at the right level.

Cross Over Trials In Clinical Research

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Author : Stephen S. Senn
language : en
Publisher: John Wiley & Sons
Release Date : 2003-07-25

Cross Over Trials In Clinical Research written by Stephen S. Senn and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-25 with Mathematics categories.

Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages. * Comprehensive coverage of the design and analysis of cross-over trials. * Each technique is carefully explained and the mathematics is kept to a minimum. * Features many real and original examples, taken from the author's vast experience. * Includes discussion of analysis using SAS, S-Plus and, GenStat, StatXact and Excel. * Written in a style suitable for statisticians and physicians alike. * Computer programs to accompany the examples in the book can be downloaded from the Web Primarily aimed at statisticians and researchers working in the pharmaceutical industry, the book will also appeal to physicians involved in clinical research and students of medical statistics.

Cross Over Experiments

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Author : DAVID. ALLDREDGE RATKOWSKY (RICHARD. EVANS, MARC A.)
language : en
Publisher: CRC Press
Release Date : 2020-06-30

Cross Over Experiments written by DAVID. ALLDREDGE RATKOWSKY (RICHARD. EVANS, MARC A.) and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-30 with categories.

Developing a model-based approach that enables any cross-over triad, of any degree of imbalance, to be analyzed both for direct effects and for residual effects using consistent procedures that employ commercially available statistical software, this timely reference/test offers a thorough guide to the analysis of cross-over designs. Illustrating practical applications throughout with lucid examples, Cross-Over Experiments provides a detailed introduction...emphasizes the importance of choosing highly efficient designs that separate treatment and carryover effects...demonstrates the exact methodology needed to handle the analysis of data...presents a powerful new methodology-previously unpublished-for the analysis of binary and categorical data...considers the effect of blocking...and much more! With extensive appendixes that fecilitate choosing am appropriate design for every experimental need, Cross-Over Experiments is an indispensable reference for statisticians; biostatisticians; biometricians; medical, pharmaceutical, agricultural, and psychological researchers; as well as an incomparable tort for upper-level undergraduate and graduate students in these disciplines. Book jacket.

Repeated Measurements And Cross Over Designs

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Author : Damaraju Raghavarao
language : en
Publisher: John Wiley & Sons
Release Date : 2014-04-14

Repeated Measurements And Cross Over Designs written by Damaraju Raghavarao and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-14 with Science categories.

An introduction to state-of-the-art experimental design approaches to better understand and interpret repeated measurement data in cross-over designs. Repeated Measurements and Cross-Over Designs: Features the close tie between the design, analysis, and presentation of results Presents principles and rules that apply very generally to most areas of research, such as clinical trials, agricultural investigations, industrial procedures, quality control procedures, and epidemiological studies Includes many practical examples, such as PK/PD studies in the pharmaceutical industry, k-sample and one sample repeated measurement designs for psychological studies, and residual effects of different treatments in controlling conditions such as asthma, blood pressure, and diabetes. Utilizes SAS(R) software to draw necessary inferences. All SAS output and data sets are available via the book's related website. This book is ideal for a broad audience including statisticians in pre-clinical research, researchers in psychology, sociology, politics, marketing, and engineering.

Experimental Design And Data Analysis For Biologists

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Author : Gerald Peter Quinn
language : en
Publisher: Cambridge University Press
Release Date : 2002-03-21

Experimental Design And Data Analysis For Biologists written by Gerald Peter Quinn and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-03-21 with Mathematics categories.

An essential textbook for any student or researcher in biology needing to design experiments, sample programs or analyse the resulting data. The text begins with a revision of estimation and hypothesis testing methods, covering both classical and Bayesian philosophies, before advancing to the analysis of linear and generalized linear models. Topics covered include linear and logistic regression, simple and complex ANOVA models (for factorial, nested, block, split-plot and repeated measures and covariance designs), and log-linear models. Multivariate techniques, including classification and ordination, are then introduced. Special emphasis is placed on checking assumptions, exploratory data analysis and presentation of results. The main analyses are illustrated with many examples from published papers and there is an extensive reference list to both the statistical and biological literature. The book is supported by a website that provides all data sets, questions for each chapter and links to software.

Variations On Split Plot And Split Block Experiment Designs

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Author : Walter T. Federer
language : en
Publisher: John Wiley & Sons
Release Date : 2007-01-22

Variations On Split Plot And Split Block Experiment Designs written by Walter T. Federer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-22 with Mathematics categories.

A complete and up-to-date discussion of optimal split plot and split block designs Variations on Split Plot and Split Block Experiment Designs provides a comprehensive treatment of the design and analysis of two types of trials that are extremely popular in practice and play an integral part in the screening of applied experimental designs--split plot and split block experiments. Illustrated with numerous examples, this book presents a theoretical background and provides two and three error terms, a thorough review of the recent work in the area of split plot and split blocked experiments, and a number of significant results. Written by renowned specialists in the field, this book features: * Discussions of non-standard designs in addition to coverage of split block and split plot designs * Two chapters on combining split plot and split block designs and missing observations, which are unique to this book and to the field of study * SAS? commands spread throughout the book, which allow readers to bypass tedious computation and reveal startling observations * Detailed formulae and thorough remarks at the end of each chapter * Extensive data sets, which are posted on the book's FTP site The design and analysis approach advocated in Variations on Split Plot and Split Block Experiment Designs is essential in creating tailor-made experiments for applied statisticians from industry, medicine, agriculture, chemistry, and other fields of study.