Cryptic Enzymes And Moonlighting
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Cryptic Enzymes And Moonlighting
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Author : Helen Irving
language : en
Publisher: Academic Press
Release Date : 2025-01-01
Cryptic Enzymes And Moonlighting written by Helen Irving and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-01 with Science categories.
Cryptic Enzymes and Moonlighting, a new volume in the Foundations and Frontiers in Enzymology series, offers a thorough overview of cryptic enzymes and moonlighting proteins in signalling cascades. It explores recent advances in research, and brings together an array of information across different fields to enable better targeting of these exciting enzymes and their interactomes. With a clear focus on the role of moonlighting and cryptic enzymes in signal transduction, the book considers examples of cryptic enzymes across species, as well in human healthy biology and pathogenesis. In early chapters, leading international contributors discuss evolutionary considerations for moonlighting proteins, moonlighting interactions in the extracellular matrix, eukaryotic moonlighting proteins, modulating, moonlighting kinases, moonlighting proteins in neurobiology signalling, metabolic enzyme moonlighting, and RNA binding and regulatory proteins. Later, methods-driven chapters discuss practical aspects of identifying hidden moonlighting domains in proteins, computational approaches and bioinformatic tools for the identification of cryptic enzymes, establishing cryptic enzyme interactomes, and assessing contributions of moonlighting proteins to signal cascades.
Protein Moonlighting In Biology And Medicine
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Author : Brian Henderson
language : en
Publisher: John Wiley & Sons
Release Date : 2016-12-12
Protein Moonlighting In Biology And Medicine written by Brian Henderson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-12 with Science categories.
The past 25 years has seen the emergence of a wealth of data suggesting that novel biological functions of known proteins play important roles in biology and medicine. This ability of proteins to exhibit more than one unique biological activity is known as protein moonlighting. Moonlighting proteins can exhibit novel biological functions, thus extending the function of the proteome, and are also implicated in the pathology of a growing number of idiopathic and infectious diseases. This book, written by a cell biologist, protein evolutionary biologist and protein bioinformatician, brings together the latest information on the structure, evolution and biological function of the growing numbers of moonlighting proteins that have been identified, and their roles in human health and disease. This information is revealing the enormous importance protein moonlighting plays in the maintenance of human health and in the induction of disease pathology. Protein Moonlighting in Biology and Medicine will be of interest to a general readership in the biological and biomedical research community.
From Structure To Signalosomes New Perspectives About Membrane Receptors And Channels
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Author : Yi Ma
language : en
Publisher: Frontiers Media SA
Release Date : 2019-09-19
From Structure To Signalosomes New Perspectives About Membrane Receptors And Channels written by Yi Ma and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-19 with categories.
Protein Moonlighting In Biology And Medicine
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Author : Brian Henderson
language : en
Publisher: John Wiley & Sons
Release Date : 2016-12-19
Protein Moonlighting In Biology And Medicine written by Brian Henderson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-19 with Science categories.
The past 25 years has seen the emergence of a wealth of data suggesting that novel biological functions of known proteins play important roles in biology and medicine. This ability of proteins to exhibit more than one unique biological activity is known as protein moonlighting. Moonlighting proteins can exhibit novel biological functions, thus extending the function of the proteome, and are also implicated in the pathology of a growing number of idiopathic and infectious diseases. This book, written by a cell biologist, protein evolutionary biologist and protein bioinformatician, brings together the latest information on the structure, evolution and biological function of the growing numbers of moonlighting proteins that have been identified, and their roles in human health and disease. This information is revealing the enormous importance protein moonlighting plays in the maintenance of human health and in the induction of disease pathology. Protein Moonlighting in Biology and Medicine will be of interest to a general readership in the biological and biomedical research community.
Moonlighting Proteins
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Author : Brian Henderson
language : en
Publisher: John Wiley & Sons
Release Date : 2017-04-17
Moonlighting Proteins written by Brian Henderson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-17 with Science categories.
Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections is a complete examination of the ways in which proteins with more than one unique biological action are able to serve as virulence factors in different bacteria. The book explores the pathogenicity of bacterial moonlighting proteins, demonstrating the plasticity of protein evolution as it relates to protein function and to bacterial communication. Highlighting the latest discoveries in the field, it details the approximately 70 known bacterial proteins with a moonlighting function related to a virulence phenomenon. Chapters describe the ways in which each moonlighting protein can function as such for a variety of bacterial pathogens and how individual bacteria can use more than one moonlighting protein as a virulence factor. The cutting-edge research contained here offers important insights into many topics, from bacterial colonization, virulence, and antibiotic resistance, to protein structure and the therapeutic potential of moonlighting proteins. Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections will be of interest to researchers and graduate students in microbiology (specifically bacteriology), immunology, cell and molecular biology, biochemistry, pathology, and protein science.
Protein Engineering Handbook
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Author : Stefan Lutz
language : en
Publisher: John Wiley & Sons
Release Date : 2012-07-31
Protein Engineering Handbook written by Stefan Lutz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-31 with Science categories.
Unparalleled in size and scope, this new major reference integrates academic and industrial knowledge into a single resource, allowing for a unique overview of the entire field. Adopting a systematic and practice-oriented approach, and including a wide range of technical and methodological information, this highly accessible handbook is an invaluable 'toolbox' for any bioengineer. In two massive volumes, it covers the full spectrum of current concepts, methods and application areas.
The Evolution Delusion
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Author : Bart Rask
language : en
Publisher: Universal-Publishers
Release Date : 2021-09-01
The Evolution Delusion written by Bart Rask and has been published by Universal-Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-01 with Science categories.
Does the field of evolution differ from other sciences? The author, a reviewer for a major medical journal, scrutinized hundreds of scientific references in evolutionary literature, adopting the same standards used for studies submitted for medical publication. The data show that there are two types of evolution, microevolution and macroevolution, with a clear boundary between them based upon the presence and absence of empirical evidence, respectively. The surprising results show that there is a universal disconnect between the data and the conclusions that claim to show the larger changes of macroevolution. The author reveals patterns of deviations from standard scientific methods in these studies. For the first time, evolutionary data have been summarized to describe both what evolution can and cannot accomplish. The author shows the reader how to recognize the different ways in which the evidence for microevolution within and between some species differs from the unsupported macroevolution of most species. Previous critiques of macroevolution have been debunked by advocates who have cited a multitude of scientific studies. This book goes beyond previous critiques by directly addressing the data from these studies to see if they do, in fact, support macroevolution-focused conclusions. Many expert counterarguments against this book’s thesis are presented and examined in the context of scientific research to reassure the reader that the author has left no stone unturned in the macroevolution debate. A theory is proposed as to why there may be no empirical evidence for macroevolution. The book concludes with a section entitled “What we see differently.” There, the author shows the reader the differences in perspective between the evolutionist and macroevolution critic as they look at and interpret the very same set of data.
Advances In Applied Microbiology
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-04-27
Advances In Applied Microbiology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-27 with Medical categories.
A compilation of up to date reviews of topics in biotechnology and the medical field. Contributions from leading authorities Informs and updates on all the latest developments in the field
Proceedings Of The National Academy Of Sciences Of The United States Of America
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Author : National Academy of Sciences (U.S.).
language : en
Publisher:
Release Date : 2007
Proceedings Of The National Academy Of Sciences Of The United States Of America written by National Academy of Sciences (U.S.). and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Science categories.
Between Pathogenicity And Commensalism
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Author : Ulrich Dobrindt
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-07-08
Between Pathogenicity And Commensalism written by Ulrich Dobrindt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-08 with Medical categories.
This comprehensive, interdisciplinary book covers different aspects of relevant human pathogens and commensals. The ongoing development of (meta-)genomic, transcriptomic, proteomic and bioinformatic analyses of pathogenic and commensal microorganisms and their host interaction provides a comprehensive introduction to the microbiological analysis of host-microbe interplay and its consequences for infection or commensalism.