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Crystallization Of Biological Macromolecules


Crystallization Of Biological Macromolecules
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Crystallization Of Biological Macromolecules


Crystallization Of Biological Macromolecules
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Author : Alexander McPherson
language : en
Publisher:
Release Date : 1999

Crystallization Of Biological Macromolecules written by Alexander McPherson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.


This extensively illustrated book by Alexander McPherson, a master practitioner, accomplishes several important goals: it presents the underlying physical and chemical principles of crystallization in an approachable way; it provides the reader with a biochemical context in which to understand and pursue successful crystal growth; it instructs the reader in practical aspects of the technologies required; and it lays out effective strategies for success that investigators can readily apply to their own experimental questions. This readable volume has been created for every investigator in biomedicine whose studies may require a shift in focus from gene to protein product, as well as chemists and physicists interested in the functions of biologically active macromolecules.



Biological Crystallization


Biological Crystallization
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Author : Jaime Gómez Morales
language : en
Publisher: MDPI
Release Date : 2019-09-23

Biological Crystallization written by Jaime Gómez Morales and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-23 with Science categories.


For at least six hundred million years, life has been a fascinating laboratory of crystallization, referred to as biomineralization. During this huge lapse of time, many organisms from diverse phyla have developed the capability to precipitate various types of minerals, exploring distinctive pathways for building sophisticated structural architectures for different purposes. The Darwinian exploration was performed by trial and error, but the success in terms of complexity and efficiency is evident. Understanding the strategies that those organisms employ for regulating the nucleation, growth, and assembly of nanocrystals to build these sophisticated devices is an intellectual challenge and a source of inspiration in fields as diverse as materials science, nanotechnology, and biomedicine. However, “Biological Crystallization” is a broader topic that includes biomineralization, but also the laboratory crystallization of biological compounds such as macromolecules, carbohydrates, or lipids, and the synthesis and fabrication of biomimetic materials by different routes. This Special Issue collects 15 contributions ranging from biological and biomimetic crystallization of calcium carbonate, calcium phosphate, and silica-carbonate self-assembled materials to the crystallization of biological macromolecules. Special attention has been paid to the fundamental phenomena of crystallization (nucleation and growth), and the applications of the crystals in biomedicine, environment, and materials science.



Twelfth International Conference On The Crystallization Of Biological Macromolecules


Twelfth International Conference On The Crystallization Of Biological Macromolecules
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Author : International Conference on the Crystallization of Biological Macromolecules. 12, 2008, Cancún
language : en
Publisher:
Release Date : 2008

Twelfth International Conference On The Crystallization Of Biological Macromolecules written by International Conference on the Crystallization of Biological Macromolecules. 12, 2008, Cancún and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.




Crystallization Of Nucleic Acids And Proteins


Crystallization Of Nucleic Acids And Proteins
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Author : Arnaud Ducruix
language : en
Publisher:
Release Date : 1999

Crystallization Of Nucleic Acids And Proteins written by Arnaud Ducruix and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Science categories.


Crystallography is the major method of determining structures of biological macromolecules yet crystallization techniques are still regarded as difficult to perform. This new edition of Crystallization of Nucleic Acids and Proteins: A Practical Approach continues in the vein of the first edition by providing a detailed and rational guide to producing crystals of proteins and nucleic acids of sufficient quantity and quality for diffraction studies. It has been thoroughly updated to include all the major new techniques such as the uses of molecular biology in structural biology (maximizing expression systems, sequence modifications to enable crystallization, and the introduction of anomalous scatterers); diagnostic analysis of prenucleation and nucleation by spectroscopic methods; and the two- dimensional electron crystallography of soluble proteins on planar lipid films. As well as an introduction to crystallogenesis, the other topics covered are: Handling macromolecular solutions, experimental design, seeding, proceeding from solutions to crystals Crystallization in gels Crystallization of nucleic acid complexes and membrane proteins Soaking techniques Preliminary characterization of crystals in order to tell whether they are suitable for diffraction studies. As with all Practical Approach books the protocols have been written by experienced researchers and are tried an tested methods. The underlying theory is brought together with the laboratory protocols to provide researchers with the conceptual and methodological tools necessary to exploit these powerful techniques. Crystallization of Nucleic Acids and Proteins: A Practical Approach 2e will be an invaluable manual of practical crystallization methods to researchers in molecular biology, crystallography, protein engineering, and biological chemistry.



Crystallization Of Biological Macromolecules


Crystallization Of Biological Macromolecules
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Author : J. Drenth
language : en
Publisher:
Release Date : 1998

Crystallization Of Biological Macromolecules written by J. Drenth and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.




Crystal Growth In Gels


Crystal Growth In Gels
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Author : Heinz K. Henisch
language : en
Publisher: Courier Corporation
Release Date : 1996-01-01

Crystal Growth In Gels written by Heinz K. Henisch and has been published by Courier Corporation this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-01-01 with Science categories.


First book ever printed on growing crystals in a gel medium provides thorough descriptions of the procedure, its history and future potential. "Concise and readable."—Science. 42 illus. 1970 edition.



Biomacromolecules


Biomacromolecules
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Author : C. Stan Tsai
language : en
Publisher: John Wiley & Sons
Release Date : 2007-01-16

Biomacromolecules written by C. Stan Tsai and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-16 with Science categories.


This book provides an integrated treatment of the structure and function of nucleic acids, proteins, and glycans, including thorough coverage of relevant computational biochemistry. The text begins with an introduction to the biomacromolecules, followed by discussion of methods of isolation and purification, physiochemical and biochemical properties, and structural characteristics. The next section of the book deals with sequence analysis, analysis of conformation using spectroscopy, chemical synthesis, and computational approaches. The following chapters discuss biomolecular interactions, enzyme action, gene transmission, signal transduction, and biomacromolecular informatics. The author concludes with presenting the latest findings in genomics, proteomics, glycomics, and biomacromolecular evolution. This text is an invaluable resource for research professionals wishing to move into genomics, proteomics, and glycomics research. It is also useful for students in biochemistry, molecular biology, bioengineering, biotechnology, and bioinformatics.



Single Particle Cryo Em Of Biological Macromolecules


Single Particle Cryo Em Of Biological Macromolecules
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Author : Robert M. Glaeser
language : en
Publisher: Institute of Physics Publishing
Release Date : 2021

Single Particle Cryo Em Of Biological Macromolecules written by Robert M. Glaeser and has been published by Institute of Physics Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Science categories.


This is an edited book that provides a comprehensive, accessible and authoritative introduction to the field of high-resolution structure analysis by single-particle cryo-EM. It covers all necessary background, ranging from the underlying concepts to practical aspects such as specimen preparation, data-collection, data analysis, and the final validation of results.



Crystallization Of Biological Macromolecules


Crystallization Of Biological Macromolecules
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Author :
language : en
Publisher:
Release Date : 1996

Crystallization Of Biological Macromolecules written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.




Macromolecular Crystallization And Crystal Perfection


Macromolecular Crystallization And Crystal Perfection
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Author : Naomi E Chayen
language : en
Publisher: OUP Oxford
Release Date : 2010-03-25

Macromolecular Crystallization And Crystal Perfection written by Naomi E Chayen and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-25 with Science categories.


The crystallization of proteins and nucleic acids and/or their complexes has become more highly automated but is still often a trial and error based approach. In parallel, a number of X-ray diffraction based techniques have been developed which explain the physical reasons limiting the resulting crystallographic data and thus show how that data may be improved. Crystal growth is also pivotal in neutron crystallography, which establishes the hydrogen and hydration aspects. Thus this book is aimed at addressing the science behind obtaining the best and most complete structural data possible for biological macromolecules, so that the detailed structural biology and chemistry of these important molecules emerge. Crystal imperfections such as twinning and lattice disorders, as well as multiple crystal situations, and their possible remedies, are also described. The small crystal frontier in micro-crystal crystallography, crystallites in powders and finally down to the proposed single molecule structure determination of X-ray lasers are covered. Overall this interdisciplinary book will interest crystal growers, X-ray and neutron physicists and the biological crystallographers, including graduate students.