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Current Analytical Trends In Drug Testing In Clinical And Forensic Toxicology


Current Analytical Trends In Drug Testing In Clinical And Forensic Toxicology
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Current Analytical Trends In Drug Testing In Clinical And Forensic Toxicology


Current Analytical Trends In Drug Testing In Clinical And Forensic Toxicology
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Author : Eugenia Gallardo
language : en
Publisher: Frontiers Media SA
Release Date : 2021-06-24

Current Analytical Trends In Drug Testing In Clinical And Forensic Toxicology written by Eugenia Gallardo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-24 with Science categories.




Molecular Clinical And Environmental Toxicology


Molecular Clinical And Environmental Toxicology
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Author : Andreas Luch
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-01

Molecular Clinical And Environmental Toxicology written by Andreas Luch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-01 with Medical categories.


Clinical Toxicology is the second volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.



Hair Analysis In Clinical And Forensic Toxicology


Hair Analysis In Clinical And Forensic Toxicology
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Author : Pascal Kintz
language : en
Publisher: Academic Press
Release Date : 2015-06-25

Hair Analysis In Clinical And Forensic Toxicology written by Pascal Kintz and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-25 with Science categories.


Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation. Topics addressed include the diagnosis of chronic excessive alcohol drinking by means of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), the early detection of new psychoactive substances, including designer drugs, the development of novel approaches to screening tests based on mass spectrometry, and the detection of prenatal exposure to psychoactive substances from the analysis of newborn hair. - Unites an international team of leading experts to provide an update on the cutting-edge advances in the toxicological analysis of hair - Demonstrates toxicological techniques relating to a variety of scenarios and exposure types - Ideal resource for the further study of the psychoactive substances, drug-facilitated crimes, ecotoxicology, analytical toxicology, occupational toxicology, toxicity testing, and forensic toxicology - Includes detailed instructions for the collection, preparation, and handling of hair, and how to best interpret results



The Analysis Of Drugs Of Abuse


The Analysis Of Drugs Of Abuse
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Author : Terry A. Gough
language : en
Publisher: John Wiley & Sons
Release Date : 1991

The Analysis Of Drugs Of Abuse written by Terry A. Gough and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.


The Analysis of Drugs of Abuse Edited by Terry A. Gough, The Laboratory of the Government Chemist, Teddington, UK Analytical techniques based on separation processes, such as chromatography and electrophoresis, are finding a growing range of applications in chemical, biochemical and clinical laboratories: The aim of this series is to provide the analyst in these laboratories with well-focused books covering individual techniques and methods. This volume, devoted to the analysis of drugs which are commonly misused, provides a comprehensive source of up-to-date information. Detailed individual chapters are written by experts in the field describing various analytical techniques and applications. A special feature of the book is its emphasis on the complementary roles of chemist, law enforcer and the law maker in combatting drugs smuggling and the need for collaboration. This book will be a valuable reference for chemists, toxicologists and forensic scientists working in the field.



Recent Advances In Therapeutic Drug Monitoring And Clinical Toxicology


Recent Advances In Therapeutic Drug Monitoring And Clinical Toxicology
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Author : Seth Kwabena Amponsah
language : en
Publisher: Springer Nature
Release Date : 2022-10-25

Recent Advances In Therapeutic Drug Monitoring And Clinical Toxicology written by Seth Kwabena Amponsah and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-25 with Medical categories.


This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges



Fundamentals Of Analytical Toxicology


Fundamentals Of Analytical Toxicology
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Author : Robert J. Flanagan
language : en
Publisher: John Wiley & Sons
Release Date : 2008-03-03

Fundamentals Of Analytical Toxicology written by Robert J. Flanagan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-03 with Science categories.


The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electro­phoresis, mass spectrometry, and immunoassay – are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results. A clearly written, practical, integrated approach to the basics of analytical toxicology. Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and links to related sites. Written by an experienced team of authors,Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development. Praise from the reviews: “This is an ambitious effort to describe in detail the many and varied aspects of the science of toxicological analysis. The 17 chapters cover every foreseeable aspect, from specimen collection through analytical techniques and quality control to pharmacological principles and interpretation of results. The authors bring together a great deal of experience in the field and have succeeded admirably in achieving their goal: "to give principles and practical information on the analysis of drugs, poisons and other relevant analytes in biological specimens...". The book is very readable and quite up-to-date, and contains many illustrative figures, charts and tables. Both the student and the practicing professional would do well to study this material carefully, as there is something here for every conceivable level of interest.” Review from Randall Baselt "This text comes highly recommended for any analytical toxicology trainee." The Bulletin of the Royal College of Pathologists “Overall, this book provides a comprehensive, thorough, clear, up to date and practical treatment of analytical toxicology at a high standard. Understanding of the text is enhanced by the use of many illustrations. Specifications, guidelines, and methods are highlighted in grey background “Boxes”. The many and up to date literature references in each chapter demonstrate the authors’ thorough work and permit easy access to deeper information. Therefore this book can be highly recommended as a valuable source of knowledge in analytical toxicology both as an introduction and for the advanced reader.” GTFCh Bulletin “Toxichem + Krimtech”, May 2008 (translated, original review in German) “Many toxicologists will add this important reference to their libraries because it competently fills a need ...” International Journal of Toxicology “The book is very well illustrated, easy to understand and pleasant to read, and contains a wealth of dedicated information.” International Journal of Environmental Analytical Chemistry



Forensic Toxicology


Forensic Toxicology
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Author : Nicholas T. Lappas
language : en
Publisher: Academic Press
Release Date : 2015-11-14

Forensic Toxicology written by Nicholas T. Lappas and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-14 with Medical categories.


Forensic Toxicology: Principles and Concepts takes the reader back to the origins of forensic toxicology providing an overview of the largely unchanging principles of the discipline. The text focuses on the major tenets in forensic toxicology, including an introduction to the discipline, fundamentals of forensic toxicology analysis, types of interpretations based on analytical forensic toxicology results, and reporting from the laboratory to the courtroom. Forensic Toxicology also contains appendices covering the principles of pharmacokinetics and pharmacodynamics, immunology and immunological assays, toxicogenomics, and case studies. - Significant emphasis on the fundamental principles and concepts of forensic toxicology - Provides students with an introduction to the core tenets of the discipline, focusing on the concepts, strategies, and methodologies utilized by professionals in the field - Coauthored by a forensic toxicologist with over 40 years of experience as a professor who has taught graduate courses in forensic and analytical toxicology and who has served as a consultant and expert witness in civil and criminal cases - The book's companion website, http://textbooks.elsevier.com/web/Manuals.aspx?isbn=9780127999678 features exclusive web-based content



First International Symposium On Current Issues Of Drug Abuse Testing


First International Symposium On Current Issues Of Drug Abuse Testing
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Author : Jordi Segura
language : en
Publisher: CRC Press
Release Date : 1991-10-29

First International Symposium On Current Issues Of Drug Abuse Testing written by Jordi Segura and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-10-29 with Medical categories.


This book elaborates on the topics covered by top experts in the field of drug testing at an international symposium held in March, 1990. The book is an excellent reference for all professionals involved in the set up, performance and interpretation of results for drug testing programs using biological fluids (especially urine). U.S. and European perspectives are presented in relation to workplace testing. Organizational aspects for reliability of drug testing include topics ranging from sample collection, chain of custody, and laboratory strategies to legal and regulatory aspects. Critical reviews of analytical methodology involve descriptions and critical issues for the major presumptive and confirmatory techniques, including immunological and gas chromatographic-mass spectrometric methodologies. The book's interpretation of results takes into account the metabolic, pharmacokinetic, pharmacodynamic and clinical aspects. The final chapters of the book include topics addressing aspects for potential international harmonization.



Applications Of Mass Spectrometry For The Provision Of Forensic Intelligence


Applications Of Mass Spectrometry For The Provision Of Forensic Intelligence
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Author : Simona Francese
language : en
Publisher: Royal Society of Chemistry
Release Date : 2023-12-20

Applications Of Mass Spectrometry For The Provision Of Forensic Intelligence written by Simona Francese and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-20 with Science categories.


Mass spectrometry is one of the most versatile analytical techniques due to the vast range of analytes that it can detect and quantify and, as such, for its contribution to a significant number of life science fields. The legal and forensics community has certainly benefited from this technique, which has been able to provide reliable evidence in court cases. Liquid Chromatography/Gas Chromatography–Mass Spectrometry (LC/GC–MS) still have a dominant role in the provision of forensic intelligence. However, in the past decade new and exciting MS-based techniques have emerged and are or have evolved to be at an operational deployment maturity, enabling either fast, ambient, non-destructive, or portable screening (or encompass all of these features). In this book, developments of LC–MS and GC–MS based techniques are covered with respect to operational practice and new applications, accompanied by other MS-based techniques that are increasing forensic opportunities and that operate on a variety of evidence types. Whilst the underpinning working principles of each relevant mass spectrometry technique are summarised, each chapter primarily focuses on its implementation in criminal investigation and court cases. In the last chapters, this book additionally covers emerging MS technologies that are at the beginning of their operational implementation journey as well as niche applications outside the fields of traditional forensic science but with a clear potential to impact future investigations (forensics beyond the courtroom). This book provides an up-to-date reference for the mass spectrometry-based tools that are currently available both as established and as emerging methods within forensic practice. It will help casework commissioning managers and forensic providers worldwide to make more informed decisions as to the forensic strategy and workflow when examining exhibits. It is also recommended to postgraduates and early career investigators with reference to the contribution that these techniques and methods could make if applied to classic forensic science practice.



Handbook Of Cannabis And Related Pathologies


Handbook Of Cannabis And Related Pathologies
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Author : Victor R Preedy
language : en
Publisher: Academic Press
Release Date : 2016-12-31

Handbook Of Cannabis And Related Pathologies written by Victor R Preedy and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-31 with Medical categories.


Handbook of Cannabis and Related Pathologies: Biology, Pharmacology, Diagnosis, and Treatment is the first book to take an interdisciplinary approach to the understanding of cannabis use and misuse. Recent worldwide trends toward decriminalizing marijuana for medical use have increased legal use of the drug and recreational use remains high, making cannabis one of the most commonly used drugs. Cannabis has a wide range of adverse neurological effects, and use and abuse can lead to physical, social, and psychopathological issues that are multifarious and complex. Effective understanding and treatment requires knowledge of the drug's effects from across scientific disciplines. This book provides an overview of the biological and pharmacological components of the cannabis plant, outlines its neurological, social, and psychopathological effects, assists in the diagnosis and screening for use and dependency, and aids researchers in developing effective treatments for cannabis-related issues and disorders. Fully illustrated, with contributions from internationally recognized experts, it is the go-to resource for neuroscientists, pharmacologists, pathologists, public-health workers, and any other researcher who needs an in-depth and cross-disciplinary understanding of cannabis and its effects. - Comprehensive chapters include an abstract, key facts, mini dictionary of terms, and summary points - Presents illustrations with at least six figures, tables, and diagrams per chapter - Provides a one-stop-shopping synopsis of everything to do with cannabis and its related pathology, from chemicals and cells, individuals and communities, and diagnosis and treatment - Offers an integrated and informed synopsis of the complex issues surrounding cannabis as a substance, its use, and its misuse