Current Challenges In Complement Diagnostics
DOWNLOAD
Download Current Challenges In Complement Diagnostics PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Current Challenges In Complement Diagnostics book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Current Challenges In Complement Diagnostics
DOWNLOAD
Author : Erik J.M. Toonen
language : en
Publisher: Frontiers Media SA
Release Date : 2023-12-14
Current Challenges In Complement Diagnostics written by Erik J.M. Toonen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-14 with Medical categories.
The complement system is an important innate immune surveillance network that has a key role in protecting our bodies against pathogens and other threats. It is a highly complex system consisting of approximately 50 soluble and cell surface-bound proteins that interact to eliminate danger signals. These signals include factors such as invading microorganisms, necrotic cells, and immune complexes. Furthermore, complement can link innate and adaptive immune responses by regulating T cell and B cell responses. The complement system is tightly regulated to avoid uncontrolled activation. Dysregulation of the complement system has been linked to numerous diseases, both rare and common. Uncontrolled or exaggerated activation can lead to life-threatening conditions such as dysregulation of coagulation, fibrinolysis, systemic inflammation and shock, and possible failure of a variety of organs such as the eyes, kidneys, skin, brain, and vascular system. In recent years, the complement system has gained increased interest, especially as a promising candidate for therapeutic intervention. Eculizumab, the first approved complement inhibitor, is highly effective for treating atypical hemolytic uremic syndrome (aHUS) and paroxysmal nocturnal hemoglobinuria (PNH). Many more drug candidates are currently evaluated in ongoing clinical trials.
Contemporary Challenges In Immunologic Testing In Clinical And Research Laboratories
DOWNLOAD
Author : Pablo Engel
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-24
Contemporary Challenges In Immunologic Testing In Clinical And Research Laboratories written by Pablo Engel and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-24 with Medical categories.
Along the last several decades, it has been progressively appreciated that immunology plays an overwhelming role in the physiology and pathophysiology of most organs, tissues, and biological systems in multicellular organisms. Accordingly, several immunological parameters are used in research and clinical laboratories with the purpose of investigating, diagnosing, and monitoring a variety of pathological conditions. The rapidly evolving field of laboratory testing in immunology poses several challenges to professionals working in research and clinical laboratories, medical practice, educational activities, in vitro diagnostic industry, and regulatory agencies. Regular analytes, such as albumin, glucose, and insulin, are homogeneous among individuals of the same species. This property represents an advantage when it comes to optimize the determination methods as well as to establish standardization and quality assessment strategies. In contrast, several immunologic analytes present tremendous variability across individuals in the same species. In fact, some are unique at the individual level. For example, the repertoire of immunoglobulins specific for a given pathogen (e.g., rubella) is specific for each individual in terms of the balance of targeted antigens and epitopes, immunoglobulin isotypes, antibody avidity, Fc glycosylation rate, and so on. As a corollary, the panel of anti-rubella antibodies is necessarily different from one to other individual. This also applies to autoantibodies and to IgE to allergens. Polymorphism is prevalent for other immunologic parameters, such as Complement components, cell receptors (cluster differentiation molecules - CD) and downstream signal transduction mediators.
Contemporary Challenges In Diagnosis And Treatment Of Predominantly Antibody Deficiency
DOWNLOAD
Author : Emily S. J. Edwards
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-25
Contemporary Challenges In Diagnosis And Treatment Of Predominantly Antibody Deficiency written by Emily S. J. Edwards and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-25 with Medical categories.
We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUI.
Issues In Prevention Diagnostics Screening Statistics And Testing 2011 Edition
DOWNLOAD
Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Issues In Prevention Diagnostics Screening Statistics And Testing 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Issues in Prevention, Diagnostics, Screening, Statistics, and Testing: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Prevention, Diagnostics, Screening, Statistics, and Testing. The editors have built Issues in Prevention, Diagnostics, Screening, Statistics, and Testing: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Prevention, Diagnostics, Screening, Statistics, and Testing in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Prevention, Diagnostics, Screening, Statistics, and Testing: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Cytopathology An Issue Of Surgical Pathology Clinics
DOWNLOAD
Author : Vickie Jo
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-09-07
Cytopathology An Issue Of Surgical Pathology Clinics written by Vickie Jo and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-07 with Medical categories.
This issue of Surgical Pathology Clinics, edited by Dr. Vickie Jo, focused on Cytopathology. Topics include--but are not limited to--Head and Neck Cytology: HPV-Associated Carcinomas; Updates in Thyroid Cytology; Salivary Gland Cytopathology; Pulmonary Cytopathology; Updates in Effusion Cytology; Updates in Gynecologic Cytology; Diagnostic Advances in Urine Cytology; Renal Neoplasms; Pancreaticobiliary Cytology; Carcinoma of Unknown Primary; Soft Tissue Neoplasms; Primary Bone Tumors; Pediatric Cytopathology; Advances in Molecular Testing Techniques in Cytological Specimens; and Circulating Tumor Cells: Applications in Cytopathology.
Current Challenges In Vaccinology
DOWNLOAD
Author : Ursula Wiedermann
language : en
Publisher: Frontiers Media SA
Release Date : 2021-02-22
Current Challenges In Vaccinology written by Ursula Wiedermann and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-22 with Medical categories.
We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS).
Current Topics And Emerging Issues In Malaria Elimination
DOWNLOAD
Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-07-21
Current Topics And Emerging Issues In Malaria Elimination written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-21 with Medical categories.
Malaria is one of the most important tropical diseases in the history of the world. This vector-borne disease has been a significant cause of morbidity and mortality in tropical countries of Africa, Asia, and Latin America. As such, this book provides updated information on epidemiological and public health research of malaria conducted in the last decade. Over four sections, chapters discuss such topics as diagnosis, epidemiology and surveillance, policy and prevention, and vector control and vaccines.
2024 Staff Guidance Note On The Imf S Engagement With Small Developing States
DOWNLOAD
Author : International Monetary Fund. Strategy, Policy, & Review Department
language : en
Publisher: International Monetary Fund
Release Date : 2024-07-25
2024 Staff Guidance Note On The Imf S Engagement With Small Developing States written by International Monetary Fund. Strategy, Policy, & Review Department and has been published by International Monetary Fund this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-25 with categories.
This guidance note provides operational guidance on the Fund’s engagement with small developing states (SDS). It highlights the unique economic characteristics and constraints facing SDS, notably in a more shock-prone world. Building on advice that applies to the full membership, the note explains how the characteristics of SDS shape Fund surveillance, financial support and program design, capacity development (CD), and collaboration with other institutions and donors. The note updates the previous version that was published in December 2017.
Laryngopharyngeal Reflux An Issue Of Otolaryngologic Clinics Of North America
DOWNLOAD
Author : Inna A. Husain
language : en
Publisher: Elsevier Health Sciences
Release Date : 2025-05-15
Laryngopharyngeal Reflux An Issue Of Otolaryngologic Clinics Of North America written by Inna A. Husain and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-15 with Medical categories.
In this issue of Otolaryngologic Clinics, guest editors Drs. Inna A. Husain and Nikki Johnston bring their considerable expertise to the topic of Laryngopharyngeal Reflux. Although it is suggested that laryngopharyngeal reflux disease (LPRD) accounts for up to 30% of outpatient otolaryngology visits, lack of formal diagnostic criteria, ease of testing, and varied treatment practices can lead to delay in care and high social/economic burden. In this edition, top experts review up-to-date information on pathophysiology of LPRD, including typical and atypical manifestations, role of diagnostic testing, updated treatment guidelines, and future directions of LPRD management. - Contains 14 relevant, practice-oriented topics including pediatric laryngopharyngeal reflux; microbiota, gut health, and LPRD; chronic cough and pulmonary manifestations of LPRD; the role of surgical intervention in LPRD; future directions for LPRD; and more - Provides in-depth clinical reviews on laryngopharyngeal reflux, offering actionable insights for clinical practice - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews
Issues In Neonatal Perinatal And Pediatric Research And Practice 2013 Edition
DOWNLOAD
Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-05-01
Issues In Neonatal Perinatal And Pediatric Research And Practice 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-01 with Medical categories.
Issues in Neonatal, Perinatal, and Pediatric Research and Practice: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Human Lactation. The editors have built Issues in Neonatal, Perinatal, and Pediatric Research and Practice: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Human Lactation in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Neonatal, Perinatal, and Pediatric Research and Practice: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.