Current Practices Regarding The Use Of Pms2 Genetic Testing
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Current Practices Regarding The Use Of Pms2 Genetic Testing
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Author : Sarah Nashed
language : en
Publisher:
Release Date : 2010
Current Practices Regarding The Use Of Pms2 Genetic Testing written by Sarah Nashed and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Genetic counseling categories.
Hereditary Colorectal Cancer
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Author : Laura Valle
language : en
Publisher: Springer
Release Date : 2018-05-04
Hereditary Colorectal Cancer written by Laura Valle and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-04 with Medical categories.
This book provides information on a wide variety of issues ranging from genetics to clinical description of the syndromes, genetic testing and counseling, and clinical management including surveillance, surgical and prophylactic interventions, and chemoprevention. Moreover, current hot issues, such as the identification of novel causal genes and the challenges we face, and the relevance of cancer risk modifiers, both genetic and environmental, are also discussed. This reference book is great for geneticists, oncologists, genetic counselors, researchers, clinicians, surgeons and nurses dedicated to, or interested in, hereditary cancer. The best and most recognized experts in the field have contributed to this project, guaranteeing updated information, accuracy and the discussion of topical issues.
Genetics Of Colorectal Cancer
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Author : John D. Potter
language : en
Publisher: Springer
Release Date : 2008-12-08
Genetics Of Colorectal Cancer written by John D. Potter and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-08 with Medical categories.
Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.
Hereditary Colorectal Cancer
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Author : Miguel A. Rodriguez-Bigas
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-10
Hereditary Colorectal Cancer written by Miguel A. Rodriguez-Bigas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-10 with Medical categories.
Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease.
Breast Cancer Gene Research And Medical Practices
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Author : Sahra Gibbon
language : en
Publisher: Routledge
Release Date : 2014-03-05
Breast Cancer Gene Research And Medical Practices written by Sahra Gibbon and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-05 with Social Science categories.
The discovery of the two inherited susceptibility genes BRCA1 and BRCA2 in the mid-1990s created the possibility of predictive genetic testing and led to the establishment of specific medical programmes for those at high risk of developing breast cancer in the UK, US and Europe. The book provides a coherent structure for examining the diversity of practices and discourses that surround developments linked to BRCA genetics, and to the evolving field of genetics more broadly. It will be of interest to students and scholars of anthropology, sociology, history of science, STS, public health and bioethics. Chapter 8 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 3.0 license.
Hereditary Colorectal Cancer
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Author : Joji Utsunomiya
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-27
Hereditary Colorectal Cancer written by Joji Utsunomiya and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-27 with Medical categories.
Since the success in chemical induction of cancer in rabbit's ear skin by K. Yamagiwa in 1915, oncologists of the world have come to believe that they can only solve their problems by means of animal experimen tation. The importance of environmental factors became moreevident in 1935 when T. Yoshida and T. Sasaki introduced azodye hepatocarcino genesis in rats. In the domain of the gastrointestinal tract, T. Sugimura has more recently accumulated enough evidence to indicate that locally active chemical mutagens are carcinogenic. In contrast, principal approaches to colorectal tumors have been quite different: emphasis has been placed on gene identification. Long before cancer of the large bowel was recognized, importance of the roles of adenomatosis coli and its familial occurrence attracted the attention of epidemiologists and geneticists. Morphological characteri zation and analysis of hereditary trends of human material have already bad a long history, and recently detailed analysis of genetic material has become feasible in the wake of rapid development in our knowledge of the oncoviruses, oncogenes, suppressor genes, chromosomal and DNA mapping, molecular mutation and so on. lt is true that in colorectal pathology, and in no other field, these areas of research have been explored more extensively and decisively. The identification of previ ously ill-defined lesions such as precancers and benign neoplasms have been improved because sequential changes can be observed in multiple samples spread over a wide area and followed up in due course.
Genetics In Medical Practice
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Author : Mihály Bartalos
language : en
Publisher:
Release Date : 1968
Genetics In Medical Practice written by Mihály Bartalos and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1968 with Medical categories.
Lynch Syndrome
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Author : Naohiro Tomita
language : en
Publisher: Springer Nature
Release Date : 2020-08-24
Lynch Syndrome written by Naohiro Tomita and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-24 with Medical categories.
This book offers a comprehensive review of Lynch Syndrome (LS), addressing both the basic and clinical aspects of this condition. Due to the recent advances in our understanding of the genetic mechanism of LS, and to new screening methods, including universal screening and/or multi-gene panel analysis, the standard treatment strategy for patients and family members of LS have been steadily improving. In this book, experts describe the disease’s manifestations, discuss state-of-the-art diagnosis and management options, and offer a cutting-edge overview of the genetic and epigenetic basis of the syndrome. Providing essential insights into this new phase in the management of LS, this book is a valuable resource not only for colorectal surgeons, but also for general gastrointestinal clinicians, gynecologists, oncologists and all basic researchers with an interest in LS.
Genetics In Endocrinology
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Author : John D. Baxter
language : en
Publisher: Lippincott Raven
Release Date : 2002
Genetics In Endocrinology written by John D. Baxter and has been published by Lippincott Raven this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
An extensive body of evidence highlights the crucial importance of endocrine genetics. Examples range from human growth disorders and obesity to cancers of the prostate and breast. A pivotal part of the Modern Endocrinology Series, this book presents major biological studies underlining the significance of data obtained from knock-out mice, as well as from transgenic animals. Gene therapy and laboratory evaluation and screening of genetic endocrine diseases are covered, as are many of the classical endocrine diseases.
Molecular Pathogenesis Of Colorectal Cancer
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Author : Kevin M. Haigis, Ph.D.
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-02
Molecular Pathogenesis Of Colorectal Cancer written by Kevin M. Haigis, Ph.D. and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-02 with Medical categories.
Colorectal cancer has for more than two decades served as the paradigm for the multi-step concept of cancer initiation and progression. Perhaps more than any other organ site, cancer of the colon is extensively characterized at the molecular level. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with emerging targeted therapies. The book will focus on the progression from the identification of mutations that drive colorectal cancer initiation and progression to the search for novel therapies to treat the disease.