Current Progress In The Understanding Of Secondary Brain Damage From Trauma And Ischemia

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Current Progress In The Understanding Of Secondary Brain Damage From Trauma And Ischemia
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Author : A. Baethmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Current Progress In The Understanding Of Secondary Brain Damage From Trauma And Ischemia written by A. Baethmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Information is provided from the basic and clinical sciences on the mechanisms damaging the brain from trauma or ischemia. New aspects involve the endoplasmic reticulum, mitochondrial failure, pathobiology of axonal injury, molecular signals activating glial elements, or the emerging therapeutical role of neurotrophins. Experimental issues involve a better analysis of the ischemic penumbra, the salvagable tissue. Therapeutic contributions reach from the environmental influence to gene expression, including neuroprotection, such as hibernation – mother nature’s experiment – or hypothermia which is reported to induce cell swelling. Treatment issues deal also with thrombolysis and combination therapies, or with the clearance of adverse blood components – LDL/fibrinogen – by a novel procedure using heparin. Other highlights are discussing the specificities of pediatric vs. adult brain trauma, or the evolving role of the Apolipoprotein-E e4 gene in severe head injury. An update is also provided on an online assessment of the patient management during the pre- and early hospital phase in Southern Bavaria. The empirical observation of neuroworsening is analyzed in further details, whether this is a specificity autonomously driving the posttraumatic course. Finally, the unsolved question why drug trials in severe head injury have failed so far in view of the promising evidence from the laboratory is subjected to an expert analysis.
Translational Research In Traumatic Brain Injury
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Author : Daniel Laskowitz
language : en
Publisher: CRC Press
Release Date : 2016-04-21
Translational Research In Traumatic Brain Injury written by Daniel Laskowitz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-21 with Medical categories.
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Nutrition And Traumatic Brain Injury
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2011-07-01
Nutrition And Traumatic Brain Injury written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-01 with Medical categories.
Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.
Applied Biological Psychology
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Author : Glen E. Getz
language : en
Publisher: Springer Publishing Company
Release Date : 2014-02-10
Applied Biological Psychology written by Glen E. Getz and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-10 with Psychology categories.
Written for graduate students and trainees in mental health, this is the only text to present neurobiology in the context of clinical issues rather than merely focusing on experimental approaches to biological psychology or structuring it along neurological systems. In clear, easily accessible language the text explains how the brain and nervous system are linked to mental disorders. It integrates information from many aspects of neurobiological research, including imaging, neuropsychology, and genetics in order to foster an in-depth understanding of the psychiatric presentation of disorders that mental health professionals encounter in their practices. To facilitate student learning and clarify the connection between neurobiological foundations and clinical presentation, the text includes case studies, cognitive data, imaging results, genetic testing results, and illustrations. It examines major psychological disorders from behavioral, emotional, biological, cognitive and neurophysiological perspectives as they relate to brain structure and the major systems. Special topic sections highlight ethical, research, and treatment concerns for mental health practitioners. Each chapter concludes with summations and review questions. Written for graduate level students in clinical, counseling, and school psychology programs, the text fulfills APA accreditation requirements for coursework in the biological bases of behavior. While the textís primary aim is to help students understand neurobiological information as an important component of a therapeutic framework, it also concisely addresses micro and macro anatomy as relates to neurobiology. Also included are such supplementary teaching materials as test questions and PowerPoint slides of illustrations. Key Features: Focuses on the connection between neurobiology and clinical presentation Presents complex information clearly and concisely Highlights special topics in neurobiology ethics, research, and treatment Integrates information from imaging, neuropsychology, and genetics testing Prepares graduate students in clinical, counseling, and school psychology for professional practice
Mechanisms Of Secondary Brain Damage From Trauma And Ischemia
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Author : A. Baethmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mechanisms Of Secondary Brain Damage From Trauma And Ischemia written by A. Baethmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Top level clinical and laboratory scientists present their most recent clinical and experimental findings and concepts. The well balanced contributions illustrate the enormous significance of the dialogue between both laboratory and clinic, ultimately for the benefit of the patients, and contribute to a better understanding of secondary brain damage from trauma and ischemia as basis to develop more effective treatment including drugs.
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1993
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medicine categories.
Mechanisms Of Secondary Brain Damage
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Author : A. Baethmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Mechanisms Of Secondary Brain Damage written by A. Baethmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
A distinction between primary and secondary brain damage of vari ous origin, particularly in acute lesions, such as head injury and ische mia is not entirely new. The concept is of practical significance, be cause it is the foremost intention of all clinical efforts to prevent, or at least attenuate the development of secondary sequelae. Primary dam age to nervous elements usually cannot be influenced by treatment. Its prevention is the objective of prophylactic measures. The current volume gathered prominent scientists and clinicians from various fields to pro vide a competent introduction and survey of the various aspects involved in secondary brain damage. It was attempted to provide criteria for the distinction between the primary and secondary phenomena on a morpho logical and functional level, on the basis of the kinetics involved and, most importantly, regarding the different specific manifestations, such as disturbances of microcirculation, aspects of the blood-brain barrier, and of cellular structure and function at a molecular level. Although it was not expected that a grand unifying hypothesis will be reached recon cilable with the many, occasionally opposing views on such a complex subject, nevertheless, the present volume attains an appropriate result. It can best be described as a mosaic of many different pieces which only as an ensemble reflect the current state of the art.
Brain Neurotrauma
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Author : Firas H. Kobeissy
language : en
Publisher: CRC Press
Release Date : 2015-02-25
Brain Neurotrauma written by Firas H. Kobeissy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-25 with Medical categories.
With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.
Neuroprotection
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Author : Mathias Bähr
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-06
Neuroprotection written by Mathias Bähr and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Medical categories.
In this first book to cover model systems, molecular mechanisms and clinical trials all in one volume internationally renowned scientists and clinicians provide a comprehensive treatment of neuroprotective strategies for all important neurological disorders. Following an overview of neurodegenerative, traumatic, and ischemic disorders, the book goes on to cover in vitro and animal model systems as well as cellular and molecular mechanisms. An extremely helpful analysis of clinical studies explains reasons for their success and failure, and the whole is rounded off with a look at the current challenges and hopes for the development of effective treatment strategies in the future.
Index Medicus
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Author :
language : en
Publisher:
Release Date : 2004
Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medicine categories.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.