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Cutaneous Drug Eruptions


Cutaneous Drug Eruptions
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Adverse Cutaneous Drug Eruptions


Adverse Cutaneous Drug Eruptions
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Author : Lars E. French
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2012

Adverse Cutaneous Drug Eruptions written by Lars E. French and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.


An indispensable tool for understanding, diagnosing and managing this common clinical problem The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1-5% for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists.



Cutaneous Drug Eruptions


Cutaneous Drug Eruptions
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Author : John C. Hall
language : en
Publisher: Springer
Release Date : 2015-08-21

Cutaneous Drug Eruptions written by John C. Hall and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-21 with Medical categories.


​The burden of cutaneous drug reactions is significant, in both outpatient and inpatient settings, and can result in morbidity and even mortality. This book is unique in its approach to this problem. This text is divided into basic principles, common drug reactions, skin conditions mimicked by drug reactions, drug reactions to the skin appendages, life-threatening drug reactions, less common drug reactions, and special groupings of drug reactions. For the clinician, the skin can only morphologically react in to many limited ways. This is also true for the pathologist. Combining these two forever linked specialties is a synergistic paradigm that greatly enhances diagnosis, and ultimately therapy, for these pernicious conditions. Drug reactions in the skin remain a common complication of therapy. True incidences of drug reactions are not available. For general discussion, the rule of 3% can be applied with reasonable assuredness. Approximately 3% of all hospitalized patients develop an adverse cutaneous drug reaction. Approximately 3% of these reactions are considered severe. Outpatient data is even more obscure, but at least 3% of dermatology clinic outpatient visits are due to a drug reaction. Cutaneous drug reactions compromise approximately 3% of all drug reactions. Even more challenging is the fact that the most vulnerable populations to drug reactions are increasing and include the elderly patients on prolonged drug therapy, and patients that use multiple drugs at the same time.



Drug Eruptions


Drug Eruptions
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Author : Haur Yueh Lee
language : en
Publisher: Springer Nature
Release Date : 2022-10-27

Drug Eruptions written by Haur Yueh Lee and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-27 with Medical categories.


Cutaneous adverse drug reactions are common and range from the benign to those which are life-threatening. The clinical presentation of these dermatoses is varied and many may mimic common skin conditions. Consequently, diagnosis in drug-induced skin disease is challenging and the treatment considerations are complex. This book aims to bridge the divide between dermatology and allergy by providing a comprehensive review on the pathomechanisms and clinical features of cutaneous adverse drug reactions. Broken up into three distinct sections: General Considerations, Reaction Patterns, and Special Drug Categories, these chapters cover the common and rare adverse skin reactions and provide information on recent advances - particularly immunopathology and pharmacogenetics - as well as highlighting new adverse drug signals and novel therapies. Drug Eruptions is a must-have resource for dermatologists, allergists, internal physicians and general practitioners.



Adverse Cutaneous Drug Reactions To Cardiovascular Drugs


Adverse Cutaneous Drug Reactions To Cardiovascular Drugs
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Author : Esen Özkaya
language : en
Publisher: Springer
Release Date : 2014-11-15

Adverse Cutaneous Drug Reactions To Cardiovascular Drugs written by Esen Özkaya and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-15 with Medical categories.


Adverse cutaneous drug reactions (ACDR) are among the most frequent events in patients receiving drug therapy. Cardiovascular (CV) drugs are an important group of drugs with potential risk of developing ACDR especially in elderly as marketing of more new drugs and their prescription continue to increase. However, like with most other drugs the exact incidence of cutaneous side effects from CV drugs is difficult to estimate due to sporadic reporting. Moreover, a reliable designation of a certain drug as the cause of a certain type of reaction can rarely be made. Apart from the well-known angioedema/urticaria from ACE inhibitors, lichen planus / lichenoid reaction from beta adrenergic blockers and photosensitivity from thiazid diuretics, ACDR from CV drugs might be seen in a wide spectrum extending to rare but life-threatening conditions such as erythroderma, Stevens-Johnson syndrome, toxic epidermal necrolysis or drug hypersensitivity syndrome. In this comprehensive review, the reported types of ACDR to CV drugs will be discussed according to drug class and the type of dermatologic reaction with special emphasize on cross-reactions and the role of patch testing in diagnosis.



Cutaneous Drug Hypersensitivity


Cutaneous Drug Hypersensitivity
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Author : Andreas J. Bircher
language : en
Publisher: Springer Nature
Release Date : 2022-07-09

Cutaneous Drug Hypersensitivity written by Andreas J. Bircher and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-09 with Medical categories.


This book covers all aspects of hypersensitivity to drugs, providing practical information for non-specialist physicians as well as addressing issues of interest to practitioners in different specialties and presenting the expert knowledge required by specialist allergists and immunologists. The opening, general section discusses basics such as clinical manifestations, histopathology, mechanisms, risk factors, drug hypersensitivity in particular populations, and the full range of diagnostic methods. The second part of the book provides concise information on the most important drug classes and guides the reader on how to proceed when patients present with a suspected reaction. For each drug class, the current level of evidence for use of the different diagnostic tools, including skin tests, provocation tests, and in vitro tests, is clarified, and management options, outlined. The inclusion of helpful tables and algorithms is designed to aid in decision making. Drug hypersensitivity is among the more complex allergological issues, and this book will meet the needs of general practitioners, internists, and specialists.



Skin Reactions To Drugs


Skin Reactions To Drugs
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Author : Kirsti Kauppinen
language : en
Publisher: CRC Press
Release Date : 2020-11-25

Skin Reactions To Drugs written by Kirsti Kauppinen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-25 with Health & Fitness categories.


Skin reactions to drugs are a ubiquitous problem-the most commonly observed drug sensitivity observed in a wide range of specialties. Skin Reactions to Drugs emphasizes the mechanisms and clinical and laboratory proof of a cause-and-effect relationship between drugs and adverse reactions. It discusses the technique of drug challenge, which has been extensively developed in Finland, but not commonly practiced in the rest of the world. In this textbook, 12 of the most common drug eruptions are described both clinically and histologically. It features a chapter on systemic contact dermatitis and also addresses cutaneous adverse drug reactions that appear in HIV-infected patients. 40 full-color photographs provide vivid examples of the reactions being discussed. A highly practical resource for practicing physicians and other health care workers, Skin Reactions to Drugs represents the platinum standard of research conducted on the causation of certain adverse reactions of skin.



Cutaneous Drug Reactions


Cutaneous Drug Reactions
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Author : Alfred Krebs
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 1992-01-01

Cutaneous Drug Reactions written by Alfred Krebs and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-01-01 with Science categories.


A Karger 'Publishing Highlights 1890-2015' title A wealth of information and its clear organization make this survey of cutaneous drug reactions an indispensable reference source for the dermatologist and any physician prescribing drugs. It is the only publication which offers a systematic approach to the whole therapeutic armamentarium, as well as to the signs and symptoms affecting skin, mucous membranes, nails and hair. The information, documented by 5600 references, is presented in tabular form to allow quick location of needed data. Convenient indexes permit the user to trace either the side effects of specific drugs and their frequency or the possible drug causes of cutaneous reactions. The drug index contains both generic and brand names. Now entirely in English, this expanded and updated edition is easy to use and serves as both a practical diagnostic aid and an important source of references to the world literature.



Drug Eruption Reference Manual


Drug Eruption Reference Manual
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Author : Jerome Z. Litt
language : en
Publisher: CRC Press
Release Date : 2002-02-20

Drug Eruption Reference Manual written by Jerome Z. Litt and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-02-20 with Medical categories.


A must for every dermatologist's office - and for hospital consultations - this updated and substantially enlarged new edition of Dr. Jerry Litt's universally acclaimed Drug Eruption Reference Manual answers the busy dermatologist's need for a comprehensive, authoritative guide to dermatologic side-effects that can develop from the use of newly approved as well as commonly prescribed and over-the-counter drugs, herbals, and supplements. Indexed by both generic and proprietary drug names as well as by reaction patterns, the new edition catalogs more than 800 generic and over 4,500 trade name drugs - cross-referenced for quick look-up - with their adverse cutaneous reactions: skin, hair, nails, mucous membranes, and others. In addition to its invaluable section of color illustrations, the Drug Eruption Reference Manual, Eighth Edition contains even more information on herbals, trace elements and supplements, and reaction patterns and the drugs responsible for them.



Monographs In Contact Allergy Volume 4


Monographs In Contact Allergy Volume 4
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Author : Anton C. de Groot
language : en
Publisher: CRC Press
Release Date : 2022-03-09

Monographs In Contact Allergy Volume 4 written by Anton C. de Groot and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-09 with Medical categories.


This fourth volume in an exciting and detailed series on contact allergens and drug allergy provides monographs of all 507 systemic drugs which have caused delayed-type cutaneous drug hypersensitivity reactions and/or occupational allergic contact dermatitis. The monographs present: Identification section; Occupational allergic contact dermatitis; and Cutaneous adverse drug reactions from systemic drugs caused by type IV (delayed-type) hypersensitivity, as shown by positive patch tests (e.g. maculopapular eruption, acute generalized exanthematous pustulosis [AGEP], symmetrical drug-related intertriginous and flexural exanthema [SDRIFE], fixed drug eruption, drug reaction with eosinophilia and systemic symptoms [DRESS], and photosensitivity). Separate chapters present an overview of the spectrum of allergic cutaneous drug reactions, diagnostic tests, immediate contact reactions (contact urticaria), and systemic drugs that have acquired delayed-type hypersensitivity only by cross-reactivity. Key Features: Presents monographs of all known systemic drugs which have caused delayed allergic cutaneous drug reactions and/or occupational allergic contact dermatitis Provides an extensive literature review of relevant topics of allergenic systemic drugs, part of which is hard or impossible to find in database searches Identifies IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing Presents immediate contact reactions (contact urticaria) from systemics drugs and delayed-type hypersensitivity in drugs caused only by cross-reactivity Covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy



Advances In Diagnosis And Management Of Cutaneous Adverse Drug Reactions


Advances In Diagnosis And Management Of Cutaneous Adverse Drug Reactions
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Author : Neil H. Shear
language : en
Publisher: Springer
Release Date : 2018-10-19

Advances In Diagnosis And Management Of Cutaneous Adverse Drug Reactions written by Neil H. Shear and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-19 with Medical categories.


This resource guides prescribers, pharmacists, and regulators with an update on the recent expansion of basic and clinical knowledge that forms a framework for understanding cutaneous reactions. This understanding will lead, in turn, to better outcomes and decisions in treatment and management, both in the clinic and in the life cycle of drug development. The skin is a common target for adverse drug events and even mild rashes can be part of life-threatening syndromes. Patients and practitioners often face important decisions about therapy after a drug eruption, including treatment, cross-reactivity with future pharmaceuticals, genetic considerations and dealing with long-term sequelae after a reaction. An international team of experts and leaders in the field share their story and insights into the scientific details and relevant clinical context.