Cyclic Nucleotide Phosphodiesterases In Health And Disease

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Cyclic Nucleotide Phosphodiesterases In Health And Disease

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Author : Joseph A. Beavo
language : en
Publisher: CRC Press
Release Date : 2006-12-05

Cyclic Nucleotide Phosphodiesterases In Health And Disease written by Joseph A. Beavo and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-05 with Medical categories.

Since the last major compendium dedicated to cyclic nucleotide phosphodiesterases (PDEs) was published over 15 years ago, an enormous amount of progress has occurred in the field. There is great need for a centralized source for key information in this burgeoning and therapeutically important area of medical research. Cyclic Nucleotide Phosph

Cyclic Nucleotide Phosphodiesterases In Health And Disease

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Author : Joseph A. Beavo
language : en
Publisher: CRC Press
Release Date : 2006-12-05

Cyclic Nucleotide Phosphodiesterases In Health And Disease written by Joseph A. Beavo and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-05 with Medical categories.

Since the last major compendium dedicated to cyclic nucleotide phosphodiesterases (PDEs) was published over 15 years ago, an enormous amount of progress has occurred in the field. There is great need for a centralized source for key information in this burgeoning and therapeutically important area of medical research. Cyclic Nucleotide Phosph

Phosphodiesterases Cns Functions And Diseases

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Author : Han-Ting Zhang
language : en
Publisher: Springer
Release Date : 2017-09-26

Phosphodiesterases Cns Functions And Diseases written by Han-Ting Zhang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-26 with Medical categories.

PDEs are a family of enzymes that catalyze the hydrolysis of intracellular cyclic nucleotides. They are implicated in a number of disorders and dysfunctions and PDE inhibitors have already proven to be effective therapies for erectile dysfunction, COPD, and psoriatic arthritis. This family of enzymes also plays a role in diseases and disorders of the CNS such as depression, anxiety, schizophrenia, and Alzheimer's Disease. Unfortunately no effective PDE inhibitors have been developed for the treatment of these diseases. The proposed book will be a comprehensive overview of the current state of basic and translational research on PDE inhibitors written by internationally recognized experts. Authors will also discuss potential PDE subtypes and splice variants in the hopes that this will spur more creative approaches to PDE targeting drugs.

Cyclic Nucleotide Phosphodiesterases

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Author : Samuel J. Strada
language : en
Publisher: Raven Press (ID)
Release Date : 1984

Cyclic Nucleotide Phosphodiesterases written by Samuel J. Strada and has been published by Raven Press (ID) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Science categories.

Cyclic Nucleotide Signaling

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Author : XiaoDong Cheng
language : en
Publisher: CRC Press
Release Date : 2021-03-30

Cyclic Nucleotide Signaling written by XiaoDong Cheng and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-30 with Cellular signal transduction categories.

Showcasing the recent progresses of the field, Cyclic Nucleotide Signaling covers the major tools and methodologies used in various areas of research. The majority of the chapters are protocol oriented, with the goal of providing clear directions for laboratory use. Students and investigators new to the field will find this book particularly informative, as will scientists already actively researching nucleotide signaling.

Cyclic Nucleotide Phosphodiesterases

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Author : Joe Beavo
language : en
Publisher:
Release Date : 1990-11-30

Cyclic Nucleotide Phosphodiesterases written by Joe Beavo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-11-30 with Medical categories.

Second volume in a series addressing topical areas important to the understanding of the control of biological processes. This volume focuses on the structure and molecular biology of isoenzymes and their role in signal transduction processes necessary for co-ordinating cellular functioning.

Microdomains In The Cardiovascular System

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Author : Viacheslav Nikolaev
language : en
Publisher: Springer
Release Date : 2017-09-19

Microdomains In The Cardiovascular System written by Viacheslav Nikolaev and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-19 with Medical categories.

The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second messengers such as cAMP, cGMP, calcium and their role in microdomain signaling are discussed. The book offers and explains methodical approaches and technical ways how to successfully analyze microdomain signaling, also in the context of disease. It further provides scientific perspectives and strategies that are based on the concept of signaling within microdomains and that can revolutionize pharmacology and eventually lead to the effective treatment of cardiovascular diseases in future.This book is written for scientists in cardiovascular research, pharmacology, molecular and cellular biology as well as medical doctors in cardiology, angiology and nephrology.

Bioenvironmental Issues Affecting Men S Reproductive And Sexual Health

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Author : Suresh C Sikka
language : en
Publisher: Academic Press
Release Date : 2017-11-14

Bioenvironmental Issues Affecting Men S Reproductive And Sexual Health written by Suresh C Sikka and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-14 with Medical categories.

Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health is structured into two parts related to men’s reproductive and sexual health with eight sections designed to enable a logical flow of such knowledge. The book is focused on the biology of key organs involved in male reproduction and the environmental influences affecting their functions with particular emphasis on clinical aspects. Individual chapters within the book range from basic to translational aspects, but all hold clinical relevance. This is an essential reference for those working and learning in the field of human reproduction, reproductive toxicology and environmental influences on reproductive and sexual health. Brings together the leading authorities working in the field of male reproduction and sexual health and how the environment affects these issues. Provides guidelines and reference values of various reproductive hormones, semen parameters, inclusion/exclusion criteria for clinical trials. Discover the most efficient methods by which to design clinical protocols for sperm safety studies and reproductive toxicology trials.

Cgmp Generators Effectors And Therapeutic Implications

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Author : Harald H. H. W. Schmidt
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-17

Cgmp Generators Effectors And Therapeutic Implications written by Harald H. H. W. Schmidt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-17 with Science categories.

After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.

Pancreatic Beta Cell In Health And Disease

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Author : Susumu Seino
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-04-08

Pancreatic Beta Cell In Health And Disease written by Susumu Seino and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-08 with Science categories.

The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis. This book provides a comprehensive review of the beta cell in health and disease. The book’s primary aim is to encourage investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.