Cytokines In Autoimmunity
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Cytokines And Autoimmune Diseases
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Author : Vijay K. Kuchroo
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-11-09
Cytokines And Autoimmune Diseases written by Vijay K. Kuchroo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-09 with Medical categories.
Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases. The many chapters offer critical reviews the basic mechanisms controlling cytokine induction and regulation, as well as the resulting production of proinflammatory and anti-inflammatory cytokines, the former of which induces organ-specific autoimmune diseases. From the vantage of these insights, they address the role of cytokines in a wide variety of autoimmune diseases, uvetis, encephalomyelitis, multiple sclerosis, human type 1 diabetes, rheumatoid arthritis, SLE, and myasthenia gravis. Authoritative and state-of-the-art, Cytokines and Autoimmune Disease highlights the enormous therapeutic potential of cytokine modulation in the treatment of autoimmune disease.
Cytokines In Autoimmunity
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Author : Fionula M. Brennan
language : en
Publisher: Springer Verlag
Release Date : 1996-01-01
Cytokines In Autoimmunity written by Fionula M. Brennan and has been published by Springer Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-01-01 with Autoimmune diseases categories.
This book documents the current state of knowledge concerning cytokines in the pathogenesis of the spectrum of human autoimmune diseases. Where appropriate, animal models of autoimmune diseases are included for comparison. This field has progressed so rapidly that it can no longer be mastered by a single group, hence this multi-authored compendium. Cytokines are now widely acknowledged to be important targets for disease intervention, as demonstrated by the success of anti-TNFa antibody therapy in the treatment of rheumatoid arthritis.
Cytokines In Autoimmunity
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Author : Fionula M. Brennan
language : en
Publisher:
Release Date : 1996
Cytokines In Autoimmunity written by Fionula M. Brennan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Autoimmune diseases categories.
Modulating Cytokines As Treatment For Autoimmune Diseases And Cancer
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Author : Erwan Mortier
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-11
Modulating Cytokines As Treatment For Autoimmune Diseases And Cancer written by Erwan Mortier and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-11 with Medical categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Cytokines And Chemokines In Autoimmune Disease
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Author : Pere Santamaria
language : en
Publisher: Springer
Release Date : 2003-01-31
Cytokines And Chemokines In Autoimmune Disease written by Pere Santamaria and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-31 with Medical categories.
This book attempts to capture recent knowledge on the role of cytokines and chemokines in autoimmunity by focusing on some of the most prevalent organ-specific or systemic autoimmune disorders. After beginning chapters on the function and structure of cytokines and chemokines, sections cover their genetics and mechanisms of action in the context of autoimmunity, and the role of different cytokines and chemokines in various autoimmune disorders. Santamaria teaches in the Department of Microbiology and Infectious Diseases at the University of Calgary, Canada.
Autoantibodies And Cytokines
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Author : Wahid Ali Khan
language : en
Publisher:
Release Date : 2019-04-24
Autoantibodies And Cytokines written by Wahid Ali Khan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-24 with Microbiology categories.
The mechanism of autoantibodies cannot be explained without the detail knowledge of cytokines and interferon. These active molecules of immunology are very much dependent on each other and their function cannot be completed without their interaction towards each other. Currently, this the most updated book on this subject that helps the readers/students to upgrade their knowledge by going through chapter by chapter. Contribution by the renounced authors across the globe makes this book really unique and consider as one of the most updated textbook on this subject. This book provides a comprehensive guide to the function and types of autoantibodies and cytokines in basic and clinical field.
Signal Transduction Pathways In Autoimmunity
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Author : Amnon Altman
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2002
Signal Transduction Pathways In Autoimmunity written by Amnon Altman and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
The chapters included in this volume represent but a few examples of the close link between aberrant signaling pathways and autoimmune diseases. They cover a variety of cells (T, B and myeloid/monocytic cells), receptors (for antigen, Fc and cytokines) and intracellular signaling molecules (kinases, phosphatases, adapters and transcription factors) in the immune system. This book brings together clinical and experimental aspects of autoimmune disease and the fundamental science of intracellular signaling pathways. Therefore, it should be of interest to clinical investigators of autoimmune diseases as wll as to basic immunologists and cell biologists interested in the molecular basis of signal transduction in the immune system.
Il 17 Il 22 And Their Producing Cells Role In Inflammation And Autoimmunity
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Author : Valérie Quesniaux
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-13
Il 17 Il 22 And Their Producing Cells Role In Inflammation And Autoimmunity written by Valérie Quesniaux and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-13 with Medical categories.
The knowledge of Th17 cells and other cell populations which secrete IL-17A, and/or IL-22 has expanded tremendously since the publication of the first edition “Th17 Cells: Role in Inflammation and Autoimmune Disease” in 2008. The present volume has been completely revised with the addition of new chapters on the IL-17 receptor family and signaling, and an in-depth review of IL-22 and innate lymphoid cells. The differentiation of naïve T cells into regulatory T cells and Th17 cells as well as the plasticity of Th17 cells is discussed. The role of IL-22 in cutaneous inflammation including psoriasis has been reviewed. In addition, the volume contains critical updates on autoimmunity, organ transplantation, tumor immunology and genetic mouse models for mechanistic studies. Lastly, the latest clinical progress in neutralizing antibodies to IL-17A, IL-17RA not only confirms the therapeutic promise foreseen in 2008, but also improves our knowledge of the pathogenesis of autoimmune diseases. In summary, this is a timely update and important review of the clinical and experimental aspects of IL-17, IL-22 and their producing cells.
Interleukins
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Author : Payam Behzadi
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-07-14
Interleukins written by Payam Behzadi and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-14 with Medical categories.
The immune system recruits a wide range of molecule groups and categories, each of which has its own function, property, and structure. Among these, interleukins play a pivotal role in supporting the immune and non-immune systems of the human body. Interleukins as effective cytokines participate in different conditions such as homeostasis, infectious diseases, autoimmune diseases, and cancers. This unique property of interleukins makes them invaluable biomarkers that can be used as important biosensors. This book is divided into three sections: “Interleukins’ Classification and Evolutionary Features”, “Autoimmune Diseases and Low Immune System”, and “Cancer and Injuries”. Chapters examine the role of various interleukins in conditions such as leukemia, rheumatoid arthritis, and allergic and autoimmune diseases.
Th 17 Cells Role In Inflammation And Autoimmune Disease
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Author : Valérie Quesniaux
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-03-12
Th 17 Cells Role In Inflammation And Autoimmune Disease written by Valérie Quesniaux and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-12 with Medical categories.
The IL-17 cytokines represent a novel family of cytokines, which defines a new effector T cell, the Th17 cell, and extend the Th1-Th2 paradigm. Th17 cells in part co-express at least IL-17A and IL-17F, IL-21 and IL-22. IL-17 A/F are produced by T cells ( and ), iNKT cells, and possibly neutrophils, dendritic cells and Paneth cells. The regulation of IL-17 family member’s expression, and the identification of effector mechanisms are an area of intense current research. Recognized regulators of IL-17A expression include the nuclear receptor ROR t, proinflammatory cyt- ines such as IL-1, IL-6 with TGF- , IL-21, IL-23 IL-25 in the absence of IFN- and IL-4, which are discussed. Recent data suggest that IL-17A may have a dual fu- tion – pro-inflammatory and anti-inflammatory- suggesting that IL-17A may also contribute to terminate inflammation. Further, a reciprocal regulation of Th17 and regulatory T cells including the role of retinoic acid and TGF- is discussed. The discovery that patients with rheumatoid arthritis, allergic disorders, psor- sis and inflammatory bowel disease express IL-17A generated interest in the medical community and instigated a flurry of experimental research on the potential role of Th17 in inflammatory diseases. Experimental studies confirmed that IL-17A is induced and is critical for the development of allergic lung inflammation, arthritis, bacterial sepsis, experimental allergic encephalomyelitis and myocarditis, as well as other inflammatory con- tions including organ transplantation. The role of IL-17F and IL-22 is still poorly defined and is only slowly emerging.
