Cytokines In Rheumatoid Arthritis
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Cytokines In Rheumatoid Arthritis
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Author : Ann-Kristin Ulfgren
language : en
Publisher:
Release Date : 2000
Cytokines In Rheumatoid Arthritis written by Ann-Kristin Ulfgren and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Rheumatoid arthritis categories.
Cytokines In Rheumatoid Arthritis Ra
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Author : Selim Nalbant
language : en
Publisher:
Release Date : 2017
Cytokines In Rheumatoid Arthritis Ra written by Selim Nalbant and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Medicine categories.
New Developments In The Pathogenesis Of Rheumatoid Arthritis
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Author : Lazaros Sakkas
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-02-22
New Developments In The Pathogenesis Of Rheumatoid Arthritis written by Lazaros Sakkas and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-22 with Medical categories.
The pathogenesis of rheumatoid arthritis (RA) is incompletely understood. HLA class II alleles and T cells have been implicated for many years. The discovery of anticitrullinated peptide antibodies (ACPAs), along with the effectiveness of biological treatments targeting cytokines, such as TNF-?, IL-6, and also T cells and B cells, reinforced the pathogenetic role of the respective factors. ACPAs, induced by cigarette smoking and periodontitis in individuals with HLA-DRB1 shared epitope, appear to be autoantigens that initiate the inflammatory immune response in RA. MicroRNAs, part of epigenetic mechanisms, which also include DNA methylation, and histone modification, as well as microbiota, the composition of microbes in body cavities, also appear to influence arthritis and are discussed in this book.
Monoclonal Antibodies
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Author : Thomas F. Kresina
language : en
Publisher: CRC Press
Release Date : 2020-08-26
Monoclonal Antibodies written by Thomas F. Kresina and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-26 with Medical categories.
Presents a sampling of new and novel approaches to the amelioration of musculoskeletal disease pathology, emphasizing prevention and therapy. Where applicable, these new technologies are focused on their application to human autoimmune diseases, but the volume mainly discusses and details the use of
Cytokines And Joint Injury
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Author : Wim B. van den Berg
language : en
Publisher: Springer
Release Date : 2012-12-06
Cytokines And Joint Injury written by Wim B. van den Berg and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The purpose of this volume in the Progress in Inflammation Research series is to provide the biomedical and clinical researcher with a state-of-the-art insight in the role of cytokines in joint inflammation and joint destruction. This is of relevance for better understanding of key processes in diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA). Apart from the impact of old and novel cytokines on joint tissues, the various chapters address the issue of targeted therapy with biological response modifiers and future interventions with carefully designed inhibitors. Spe cial attention is given to elements of synovial cell activation, cell-cell interaction, cytokine interplay as well as mechanisms of cartilage destruction and bone erosion. In addition to an outline of the role of established cytokines, such as TNF, IL-l and IL-6, new information is given on the novel cytokines IL-15, IL-17 and IL-18 and their positioning in the complex cytokine interplay. Cytokine regulation of destructive enzymes, RANKL, the endogenous inhibitor OPG and their crucial roles as central players in joint erosion are highlighted. Together, the chapters provide a complete and balanced view on pivotal cytokines and joint pathology.
Cytokines In Rheumatoid Arthritis
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Author :
language : en
Publisher:
Release Date : 1996
Cytokines In Rheumatoid Arthritis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.
Cytokines And Autoimmune Diseases
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Author : Vijay K. Kuchroo
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-11-09
Cytokines And Autoimmune Diseases written by Vijay K. Kuchroo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-09 with Medical categories.
Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases. The many chapters offer critical reviews the basic mechanisms controlling cytokine induction and regulation, as well as the resulting production of proinflammatory and anti-inflammatory cytokines, the former of which induces organ-specific autoimmune diseases. From the vantage of these insights, they address the role of cytokines in a wide variety of autoimmune diseases, uvetis, encephalomyelitis, multiple sclerosis, human type 1 diabetes, rheumatoid arthritis, SLE, and myasthenia gravis. Authoritative and state-of-the-art, Cytokines and Autoimmune Disease highlights the enormous therapeutic potential of cytokine modulation in the treatment of autoimmune disease.
Immunomodulatory Functions Of Fibroblast Like Synoviocytes In Joint Inflammation And Destruction During Rheumatoid Arthritis
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Author : Hanshi Xu
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-03
Immunomodulatory Functions Of Fibroblast Like Synoviocytes In Joint Inflammation And Destruction During Rheumatoid Arthritis written by Hanshi Xu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-03 with categories.
Autoantibodies And Cytokines
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Author : Wahid Ali Khan
language : en
Publisher:
Release Date : 2019-04-24
Autoantibodies And Cytokines written by Wahid Ali Khan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-24 with Microbiology categories.
The mechanism of autoantibodies cannot be explained without the detail knowledge of cytokines and interferon. These active molecules of immunology are very much dependent on each other and their function cannot be completed without their interaction towards each other. Currently, this the most updated book on this subject that helps the readers/students to upgrade their knowledge by going through chapter by chapter. Contribution by the renounced authors across the globe makes this book really unique and consider as one of the most updated textbook on this subject. This book provides a comprehensive guide to the function and types of autoantibodies and cytokines in basic and clinical field.
Il 1ra In The Treatment Of Rheumatoid Arthritis Pocketbook
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Author : Barry Bresnihan
language : en
Publisher: CRC Press
Release Date : 2001-12-20
Il 1ra In The Treatment Of Rheumatoid Arthritis Pocketbook written by Barry Bresnihan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-12-20 with Medical categories.
In recent years researchers have gained a greater understanding of the immunological and inflammatory mechanisms underlying rheumatoid arthritis. Much of their efforts have centred on the role of the cytokine network in the pathophysiology of the disease. On the basis of these discoveries pharmaceutical companies have developed several potential biologic agents aimed at addressing cytokine imbalance and its subsequent effects on cartilage damage and joint destruction in rheumatoid arthritis. This pocketbook will provide an overview of the role of cytokines in the disease process, with a particular focus on one cytokine, interleukin-1 (IL-1) and on the therapeutic efficacy of its inhibition.