Dancing Protein Clouds Intrinsically Disordered Proteins In Health And Disease Part A
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Dancing Protein Clouds Intrinsically Disordered Proteins In Health And Disease Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-09-12
Dancing Protein Clouds Intrinsically Disordered Proteins In Health And Disease Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-12 with Science categories.
"Dancing protein clouds: Intrinsically disordered proteins in the norm and pathology" represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain.
Dancing Protein Clouds Intrinsically Disordered Proteins In Health And Disease Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-09-11
Dancing Protein Clouds Intrinsically Disordered Proteins In Health And Disease Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-11 with Science categories.
"Dancing protein clouds: Intrinsically disordered proteins in the norm and pathology" represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain. - Provides some recent studies on the intrinsically disordered proteins and their functions, as well as on the involvement of intrinsically disordered proteins in pthogenesis of various diseases - Contains numerous illustrative materials (color figures, diagrams, and tables) to help the readers to delve in the information provided - Includes contributions from recognized experts in the field
Dancing Protein Clouds Intrinsically Disordered Proteins In Health And Disease Part A
DOWNLOAD
Author :
language : en
Publisher: Academic Press
Release Date : 2019-09-12
Dancing Protein Clouds Intrinsically Disordered Proteins In Health And Disease Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-12 with Science categories.
"Dancing protein clouds: Intrinsically disordered proteins in the norm and pathology" represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain.
Dancing Protein Clouds Intrinsically Disordered Proteins In Health And Disease Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-08-19
Dancing Protein Clouds Intrinsically Disordered Proteins In Health And Disease Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-19 with Science categories.
Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B, represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain. - Provides some recent studies on the intrinsically disordered proteins and their functions, as well as on the involvement of intrinsically disordered proteins in pthogenesis of various diseases - Contains numerous illustrative materials (color figures, diagrams, and tables) to help the readers to delve in the information provided - Includes contributions from recognized experts in the field
Dancing Protein Clouds Intrinsically Disordered Proteins In The Norm And Pathology Part C
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-10-14
Dancing Protein Clouds Intrinsically Disordered Proteins In The Norm And Pathology Part C written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-14 with Science categories.
Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C, Volume 183 represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this volume include discussions on the evolution of disorder, consideration of the peculiarities of phase separation of the prion protein, a general discussion of the relationships between intrinsic disorder and protein functions, coverage of the structural and functional characterization of several important intrinsically disordered proteins, such as transcription factors, outer membrane porins, trans-membrane and membrane associated proteins with ID regions, discussion of molecular simulations of IDPs, and much more. - Provides recent studies on the intrinsically disordered proteins and their functions, along with the involvement of intrinsically disordered proteins in the pathogenesis of various diseases - Contains numerous illustrative materials (color figures, diagrams and tables) to help readers delve into the information provided - Includes contributions from recognized experts in the field
Amino Acids Peptides And Proteins
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Author : Maxim Ryadnov
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-12-07
Amino Acids Peptides And Proteins written by Maxim Ryadnov and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-07 with Science categories.
Amino Acids, Peptides and Proteins is a broad ranging title comprising comprehensive and critical reviews of significant developments at the biology and chemistry interface. Compiled by leading researchers in their subject, this volume incorporates current trends and emerging areas in topics ranging from enzymatic halogenation, unnatural amino acids in peptide and protein chemistry and detection of protein post-translational modifications by mass spectrometry. Appealing broadly to researchers in academia and industry, it will be of great benefit to any researcher wanting a succinct reference in this field and looking at the future.
Amino Acids Peptides And Proteins Volume 44
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Author : Maxim Ryadnov
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-12-08
Amino Acids Peptides And Proteins Volume 44 written by Maxim Ryadnov and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-08 with Science categories.
Compiled by leading researchers, Amino Acids, Peptides and Proteins is a broad ranging title comprising comprehensive and critical reviews of significant developments at the biology and chemistry interface.
Protein Deimination In Human Health And Disease
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Author : Anthony P. Nicholas
language : en
Publisher: Springer
Release Date : 2017-09-20
Protein Deimination In Human Health And Disease written by Anthony P. Nicholas and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-20 with Medical categories.
Published in 2014, Protein Deimination in Human Health and Disease was the first book on this novel post-translational modification, in which selected positively-charged arginine amino acids are converted to neutral citrulline amino acids by the peptidyl-arginine deiminase (PAD) family of enzymes. This area of research continues to expand rapidly, necessitating the need for this second edition. Chronicling the latest inflammatory, epigenetic, neurodegenerative, and carcinogenic processes, Protein Deimination in Human Health and Disease, Second Edition, updates the latest advances in deimination research, including new information on PAD enzyme structure and activity, and how PAD knock-out animals are being used to study known and newly-discovered links to various human diseases. The first edition outlined what was known about citrullinated proteins in normal tissues such as skin and hair, as well as in maladies such as rheumatoid arthritis (RA), multiple sclerosis (MS), Alzheimer’s disease (AD), glaucoma, peripheral nerve injury, neonatal hypoxic brain damage, and breast cancer. This second edition addresses numerous additional disorders such as diabetes, asthma, traumatic brain injury, inflammatory bowel disease, lupus, bone disease, heart failure, fronto-temporal dementia, and prostate and colon cancer. It also provides updates on the deimination research covering the three seminal diseases first linked to this process (RA, MS and AD), and details how auto-antibodies against citrullinated proteins contribute to disease. In addition, new hypotheses on the possible pathologic mechanisms of citrullinated myelin basic protein and glial fibrillary acidic protein are also proposed. This second edition also outlines the latest developments in therapeutic strategies, including the use of new PAD antagonists and innovative techniques such as micro-vescicles and stem cells as possible mechanisms to treat these conditions.
Intrinsically Disordered Proteins
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Author : Nicola Salvi
language : en
Publisher: Academic Press
Release Date : 2019-06-14
Intrinsically Disordered Proteins written by Nicola Salvi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-14 with Science categories.
Intrinsically Disordered Proteins: Dynamics, Binding, and Function thoroughly examines and ties together the fundamental biochemical functions of intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs), including signaling, binding, and regulation, with the methodology for study and the associated pathways for drug design and therapeutic intervention. The role of new mechanistic, computational, and experimental approaches in IDP study are explored in depth, with methods for the characterization of IDP dynamics; models, simulations, and mechanisms of IDP and IDR binding; and biological and medical implications of IDP dynamics prominently featured. Written and edited by leading scientists in the field, this book explores groundbreaking areas such as ensemble descriptions of IDPs and IDRs, single-molecule studies of IDPs and IDRs, IDPs and IDRs in membraneless organelles, and molecular mechanisms of fibrillation of IDPs. Intrinsically Disordered Proteins provides students and researchers in biochemistry, molecular biology, and applied microbiology with a comprehensive and updated discussion of the complex dynamics of IDPs and IDRs. - Provides in-depth discussion of fundamental IDP and IDR dynamics, function, and binding, with mechanistic insight to support new drug development - Describes the role of new computational and experimental approaches in characterizing the binding of IDPs to their functional targets - Features chapter contributions from international experts in IDP and IDR biochemical function and methods of study
Middle Molecular Strategy
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Author : Koichi Fukase
language : en
Publisher: Springer Nature
Release Date : 2021-07-13
Middle Molecular Strategy written by Koichi Fukase and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-13 with Science categories.
This book highlights recently discovered aspects of “middle-size molecules,” focusing on (1) their unique bio-functions on the basis of derivatives and conjugates of natural products, saccharides, peptides, and nucleotides; (2) the synthesis of structurally complex natural products; (3) special synthetic methods for π-conjugated functional molecules; and (4) novel synthetic methods using flow chemistry. Given its scope, the book is of interest to industrial researchers and graduate students in the fields of organic chemistry, medicinal chemistry, and materials science.