Dancing With My Cancer Demon All The Way To A Nih Nci Immunotherapy Clinical Trial B W
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Dancing With My Cancer Demon All The Way To A Nih Nci Immunotherapy Clinical Trial B W
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Author : Clark B. Hanmer, M.D.
language : en
Publisher: Lulu.com
Release Date : 2016-11-22
Dancing With My Cancer Demon All The Way To A Nih Nci Immunotherapy Clinical Trial B W written by Clark B. Hanmer, M.D. and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-22 with Biography & Autobiography categories.
This is not your typical death and dying, search for the meaning of life, cancer story. More like a dance lesson. I'm a family doc who flipped to Stage-4 cancer overnight. Making my way with this terrible problem, I've managed to survive a year, learning a lot in the process. This is my journal, with commentary from friends, written as events unfolded. I offer it for others to find insights and make their dance a little easier. Subjects explored: CANCER: the emotional roller coaster, managing well-wishers, keeping everyone up to date, sorting treatment options and clinical trials. HEALTH CARE: find good doctors, manage your medical record, rebut insurance denials, and find an advocate to assist. DOCTORING: my rural practice stories explore what it takes to become a wise physician, by learning from patients. SURVIVING: Resilience, faith, personal choice, palliative care, and advanced directives. LIVING: Reconnecting and having some fun. Making the best of the time we have left.
Cancer Therapeutic Targets
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Author : John L. Marshall
language : en
Publisher: Springer
Release Date : 2017-06-17
Cancer Therapeutic Targets written by John L. Marshall and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-17 with Medical categories.
In the past decade, we have experienced an explosion of new information about cancer therapeutic targets. Many of the targets have been validated by the discovery and approval of new medicines which have been approved for the treatment of cancer. On the heels of these successes, innumerable new targets and new potential therapeutics are being developed by many different groups including government agencies, pharmaceutical companies, biotechnology companies, academic institutions, and individual investigators. Understanding the expanding "universe" of cancer therapies is therefore becoming impossible and no single source exists which serves as a reference for the involved parties. Further, the interested parties have vastly different areas of expertise, from focused laboratory based science, to clinical research, to corporate and regulatory oversight. The text would be updated every two years, more often depending on pace of change, interest and sales. While useful online, this reference book would likely be kept in hard copy as well.
Inflammation Infection And Microbiome In Cancers
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Author : Jun Sun
language : en
Publisher: Springer Nature
Release Date : 2021-04-20
Inflammation Infection And Microbiome In Cancers written by Jun Sun and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-20 with Medical categories.
This book offers a summary and discussion of the advances of inflammation and infection in various cancers. The authors cover the classically known virus infections in cancer, novel roles of other pathogens (e.g. bacteria and fungi), as well as biomarkers for diagnosis and therapy. Further, the chapters highlight the progress of immune therapy, stem cells and the role of the microbiome in the pathophysiology of cancers. Readers will gain insights into complex microbial communities, that inhabit most external human surfaces and play a key role in health and disease. Perturbations of host-microbe interactions often lead to altered host responses that can promote cancer development. Thus, this book highlights emerging roles of the microbiome in pathogenesis of cancers and outcome of therapy. The focus is on mechanistic concepts that underlie the complex relationships between host and microbes. Approaches that can inhibit infection, suppress chronic inflammation and reverse the dysbiosis are discussed, as a means for restoring the balance between host and microbes. This comprehensive work will be beneficial to researchers and students interested in infectious diseases, microbiome, and cancer as well as clinicians and general physiologists.
Targeted Therapies For Lung Cancer
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Author : Ravi Salgia
language : en
Publisher: Springer
Release Date : 2019-06-26
Targeted Therapies For Lung Cancer written by Ravi Salgia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-26 with Medical categories.
This book contextualizes translational research and provides an up to date progress report on therapies that are currently being targeted in lung cancer. It is now well established that there is tremendous heterogeneity among cancer cells both at the inter- and intra-tumoral level. Further, a growing body of work highlights the importance of targeted therapies and personalized medicine in treating cancer patients. In contrast to conventional therapies that are typically administered to the average patient regardless of the patient’s genotype, targeted therapies are tailored to patients with specific traits. Nonetheless, such genetic changes can be disease-specific and/or target specific; thus, the book addresses these issues manifested in the somatically acquired genetic changes of the targeted gene. Each chapter is written by a leading medical oncologist who specializes in thoracic oncology and is devoted to a particular target in a specific indication. Contributors provide an in-depth review of the literature covering the mechanisms underlying signaling, potential cross talk between the target and downstream signaling, and potential emergence of drug resistance.
Ebmt Handbook
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Author :
language : en
Publisher:
Release Date : 2025
Ebmt Handbook written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025 with categories.
Therapeutic Nuclear Medicine
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Author : Richard P. Baum
language : en
Publisher: Springer
Release Date : 2014-08-16
Therapeutic Nuclear Medicine written by Richard P. Baum and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-16 with Medical categories.
The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.
Handbook Of Anticancer Pharmacokinetics And Pharmacodynamics
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Author : William Figg
language : en
Publisher: Humana Press
Release Date : 2004-03-26
Handbook Of Anticancer Pharmacokinetics And Pharmacodynamics written by William Figg and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-03-26 with Medical categories.
Leading investigators synthesize the entire laboratory and clinical process of developing anticancer drugs to create a single indispensable reference that covers all the steps from the identification of cancer-specific targets to phase III clinical trials. These expert authors provide their best guidance on a wide variety of issues, including clinical trial design, preclinical screening, and the development and validation of bioanalytic methods. The chapters on identifying agents to test in phase III trials and on trial design for the approval of new anticancer agents offer a unique roadmap for moving an agent to NDA submission.
Targeted Intracellular Drug Delivery By Receptor Mediated Endocytosis
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Author : Padma V. Devarajan
language : en
Publisher: Springer Nature
Release Date : 2019-11-09
Targeted Intracellular Drug Delivery By Receptor Mediated Endocytosis written by Padma V. Devarajan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-09 with Medical categories.
This book elaborates on drug delivery targeting via intracellular delivery, specifically through the Receptor Mediated Endocytosis (RME) approach, due to the involvement of cellular receptors in various grave diseases. Targeted delivery relies on two basic approaches, passive and active targeting. While passive targeting approaches have shown great promise, the improved selectivity achieved with active targeting approaches has resulted in significantly higher efficacy. Interestingly there are numerous strategies for active targeting, many of which are already highlighted in , Targeted Drug Delivery: Concepts and Applications. Nevertheless an exciting and practical strategy for active targeting, which could enable high intracellular delivery, is through exploitation of RME. Cells in the body express receptors to enable various physiological and biochemical processes. As a result, many of these receptors are overexpressed in pathological conditions, or newer receptors expressed due to defective cellular functioning. RME is based on exploitation of such receptors to achieve intracellular delivery. While targeted delivery can have manifold applications, in this book we focus on two major and challenging therapeutic areas; i) Cancer and ii) Infectious Diseases. Targeted Intracellular Drug Delivery by Receptor Medicated Endocytosis discusses the major receptors that are useful for targeted delivery for these afflictions. A major section of this book is dedicated to details regarding their occurrence and location, the recognition domain of the receptor, structure activity relationship of substrate /ligand for selective binding, ligands explored, antagonists for ligand binding and relevance of these aspects for therapy of cancer and infectious diseases. These facets are elucidated with the help of specific examples from academic research and also emphasize commercial products, wherever relevant. In vitro cellular models relied on for assessing receptor mediated cellular targeting and in vivo models depicting clinical efficacy are focused on in a separate section. Finally, we briefly discuss the regulatory and toxicity issues that may be associated specifically with the RME approach of intracellular drug delivery.
Science Of Ashwagandha Preventive And Therapeutic Potentials
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Author : Sunil C. Kaul
language : en
Publisher: Springer
Release Date : 2017-09-13
Science Of Ashwagandha Preventive And Therapeutic Potentials written by Sunil C. Kaul and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-13 with Medical categories.
Rapidly increasing aging population and environmental stressors are the two main global concerns of increasing incidence of a variety of pathologies in the modern society. The complex etiologies and pathologies cause major challenges to disease treatment. On the other hand, several herbs are known for their health-caring and disease-curing activities. Ashwagandha, a popular herb in Indian traditional home medicine, Ayurveda, has gathered increasing recognition in recent years when the chemically synthesized drugs for single target therapies showed limited success and adverse toxic effects. Ashwagandha is known as a powerful adaptogen and trusted to enhance function of the brain, reproductive system, cell-mediated immunity and increase the body's defense against disease, and possess anti-inflammatory, anticancer and anti-arthritic activities. In this book, for the first time, we provide a complete portrait on scientific understanding of the effects of Ashwagandha and its active principles for a variety of preventive and therapeutic activities.
Immune Mediated Diseases
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Author : Michael R Shurin
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-09-23
Immune Mediated Diseases written by Michael R Shurin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-23 with Medical categories.
This volume includes contributions from the speakers of the Second IMD Congress (September 10-15, 2007; Moscow, Russia) who were eager to share some of the academic and clinical enthusiasm that defines the IMD meetings. The goal of the International Immune-Mediated Diseases: From Theory to Therapy (IMD) Congress is to bring the world’s best immunologists and clinicians to Moscow.