Inflammation Infection And Microbiome In Cancers

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Inflammation Infection And Microbiome In Cancers

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Author : Jun Sun
language : en
Publisher: Springer Nature
Release Date : 2021-04-20

Inflammation Infection And Microbiome In Cancers written by Jun Sun and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-20 with Medical categories.

This book offers a summary and discussion of the advances of inflammation and infection in various cancers. The authors cover the classically known virus infections in cancer, novel roles of other pathogens (e.g. bacteria and fungi), as well as biomarkers for diagnosis and therapy. Further, the chapters highlight the progress of immune therapy, stem cells and the role of the microbiome in the pathophysiology of cancers. Readers will gain insights into complex microbial communities, that inhabit most external human surfaces and play a key role in health and disease. Perturbations of host-microbe interactions often lead to altered host responses that can promote cancer development. Thus, this book highlights emerging roles of the microbiome in pathogenesis of cancers and outcome of therapy. The focus is on mechanistic concepts that underlie the complex relationships between host and microbes. Approaches that can inhibit infection, suppress chronic inflammation and reverse the dysbiosis are discussed, as a means for restoring the balance between host and microbes. This comprehensive work will be beneficial to researchers and students interested in infectious diseases, microbiome, and cancer as well as clinicians and general physiologists.

Microbiome And Cancer

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Author : Erle S. Robertson
language : en
Publisher: Springer
Release Date : 2019-02-20

Microbiome And Cancer written by Erle S. Robertson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-20 with Medical categories.

This book ventures into a new and exciting area of discovery that directly ties our current knowledge of cancer to the discovery of microorganisms associated with different types of cancers. Recent studies demonstrate that microorganisms are directly linked to the establishment of cancers and that they can also contribute to the initiation, as well as persistence of, the cancers. Microbiome and Cancer covers the current knowledge of microbiome and its association with human cancers. It provides important reading for novices, senior undergraduates in cancer and microbiology, graduate students, junior investigators, residents, fellows and established investigators in the fields of cancer and microbiology. We cover areas related to known, broad concepts in microbiology and how they can relate to the ongoing discoveries of the micro-environment and the changes in the metabolic and physiologic states in that micro-environment, which are important for the ongoing nurturing and survival of the poly-microbial content that dictates activities in that micro-environment. We cover the interactions of microorganisms associated with gastric carcinomas, which are important for driving this particular cancer. Additional areas include oral cancers, skin cancers, ovarian cancers, breast cancers, nasopharyngeal cancers, lung cancers, mesotheliomas, Hodgkin’s and non-Hodgkin’s lymphomas, glioblastoma multiforme, hepatocellular carcinomas, as well as the inflammatory response related to the infectious agents in cancers. This book covers the metabolic changes that occur because of infection and their support for development of cancers, chronic infection and development of therapeutic strategies for detection and control of the infection. The field of microbiome research has exploded over the last five years, and we are now understanding more and more about the context in which microorganisms can contribute to the onset of cancers in humans. The field of microbiome research has demonstrated that the human body has specific biomes for tissues and that changes in these biomes at the specific organ sites can result in disease. These changes can result in dramatic differences in metabolic shifts that, together with genetic mutations, will produce the perfect niche for establishment of the particular infection programmes in that organ site. We are just beginning to understand what those changes are and how they influence the disease state. Overall, we hope to bring together the varying degrees of fluctuations in the microbiome at the major organ sites and how these changes affect the normal cellular processes because of dysregulation, leading to proliferation of the associated tissues.

Microbiome In Gastrointestinal Cancer

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Author : Jun Yu
language : en
Publisher: Springer Nature
Release Date : 2023-01-16

Microbiome In Gastrointestinal Cancer written by Jun Yu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-16 with Medical categories.

This book covers state-of-the-art topics covering evidences indicate that the gut microbiota can be harnessed for cancer prevention as well as to modulate the efficacy of chemotherapy and immunotherapy. This book includes: 1) characterization of the dysregulated microbiome in gastrointestinal cancers (Chapters 1-6); 2) the molecular mechanism of action of gut microbiota via microbial metabolites and direct interaction with host cancer or immune cells (Chapters 7-11); 3) key methodologies for studying the role of gut microbiota in cancers (Chapters 12-13); and 4) the potential application of gut microbes for the prevention and treatment of gastrointestinal cancers (Chapters 14-17). The contributors are international experts in molecular and cellular biology, microbiology, metabolomics, bioinformatics and physician scientists to provide in-depth reviews of this subject. This book provides a rich resource of information on this important topic for graduate students, basic researchers and physicians.

The Microbiome In Cancer And Autoimmunity Part A

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Author :
language : en
Publisher: Academic Press
Release Date : 2025-07-01

The Microbiome In Cancer And Autoimmunity Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-01 with Science categories.

Microbiome in Cancer and Autoimmunity - Part A, Volume 394 offers a comprehensive exploration of the intricate relationship between the human microbiome and the development of cancer and autoimmune diseases. Delving into cutting-edge research and clinical insights, this groundbreaking work elucidates the role of microbial communities in influencing immune responses, disease pathways, and therapeutic outcomes. From deciphering the molecular mechanisms underlying microbiome-host interactions to unraveling the impact of dysbiosis on disease progression, the book provides a multifaceted analysis of the microbiome's pivotal role in cancer and autoimmunity.With contributions from leading experts in the field, this book serves as a pivotal resource for researchers, clinicians, and healthcare professionals seeking to understand and harness the therapeutic potential of the microbiome in combating cancer and autoimmune conditions. - Discusses the Interconnection of Microbiome with Cancer and Autoimmunity - Explores the complex relationship between the microbiome and the development, progression, and treatment of cancer and autoimmune diseases - Covers the Role of Microbial Communities, including Analysis of the composition, diversity, and functions of microbial communities in influencing cancer and autoimmune conditions - Delves into how the microbiome influences immune responses, inflammation, and immune tolerance in the context of cancer and autoimmunity

The Interplay Of Gut Microbiome Between Infection And Inflammation

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Author : Piyush Baindara
language : en
Publisher: Frontiers Media SA
Release Date : 2024-11-21

The Interplay Of Gut Microbiome Between Infection And Inflammation written by Piyush Baindara and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-21 with Science categories.

Gut microbiome has become the greatest attraction of the research community in the recent past due to their diverse compositions and involvement in the regulation of human health and disease. With the development of high-throughput genomic analysis and other scientific advances, the gut microbiome has emerged as a potential therapeutic target for both infectious and autoimmune diseases. Especially, respiratory infections such as tuberculosis and COVID-19 have been shown to have a major impact on disease pathogenesis caused by gut dysbiosis which further affects the regulation of the gut-lung axis and contributes to disease progression. On the other hand, gut dysbiosis has been reported as a key player in multiple chronic diseases including gastrointestinal metabolic, neurological, cardiovascular, and respiratory inflammatory disease that includes diabetes, obesity, intestinal bowel disease, and cancer, etc. Despite, the known involvement, the mechanistic role of gut microbiota in disease pathogenesis is still undermined. The current research topic is focused on the mechanistic interplay of gut microbiota between infection and inflammation and thus overall disease progression. Strategies to overcome gut dysbiosis, gut microbiome transfer, the influence of antibiotics on the gut microbiome, modulation of gut microbiome via drug-repurposing, and host-directed therapies targeting the gut microbiome will also be discussed.

Inflammation And Cancer

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Author : Bharat B. Aggarwal
language : en
Publisher: Springer
Release Date : 2014-05-12

Inflammation And Cancer written by Bharat B. Aggarwal and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-12 with Medical categories.

This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.

Exploring The Gut Microbiome In Cancer

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Author : Zodwa Dlamini
language : en
Publisher: CRC Press
Release Date : 2024-10-04

Exploring The Gut Microbiome In Cancer written by Zodwa Dlamini and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-04 with Medical categories.

This book explores the relationship between the gut microbiome and cancer, illuminating various facets from fundamental roles to personalized therapies. It provides a comprehensive overview of the impact of the gut microbiome on cancer development, offering potential for innovative diagnostic and treatment approaches. The book discusses the role of dysbiosis in cancer development, the influence of the microbiome on treatment responses, and strategies to modulate the microbiome for enhanced therapies. It reviews the influence of the gut microbiome on immunotherapy resistance and chemoresistance in cancer patients. Additionally, the book presents gut microbiome biomarkers for cancer diagnosis and prognosis, the implication of the gut-brain axis on cancer development and progression, and the impact of diet and lifestyle on the microbiome. Towards the end, the book investigates the role of the gut microbiome in pediatric cancer and provides an outlook on the future challenges, technological advancements, and ethical considerations of gut microbiome research in the context of personalized cancer therapies. This book is intended for cancer researchers, medical oncologists, clinicians, pharmacologists, translational investigators, and medical students.

Interplay Of Infection And Microbiome

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Author : Wilhelmina May Huston
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-06

Interplay Of Infection And Microbiome written by Wilhelmina May Huston and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-06 with categories.

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

The Microbiome In Cancer And Autoimmunity Part B

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Author :
language : en
Publisher: Academic Press
Release Date : 2025-08-01

The Microbiome In Cancer And Autoimmunity Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-08-01 with Science categories.

Microbiome in Cancer and Autoimmunity - Part B, Volume 395 offers a comprehensive exploration of the intricate relationship between the human microbiome and the development of cancer and autoimmune diseases. Delving into cutting-edge research and clinical insights, this groundbreaking work elucidates the role of microbial communities in influencing immune responses, disease pathways, and therapeutic outcomes. Specific chapters cover the Effect of Microbial Dysbiosis on Autoimmune-Associated Inflammation, Gut Microbiota and Systemic Immune Responses in Cancer, The role of microbiome in gastrointestinal cancer, Cancer and Microbiome-Targeted Therapies, Autoimmune disease and Microbiome Targeted Therapies, and the Effect of Diet and Lifestyle on Microbiome Composition. - Explores the interconnection of Microbiome with Cancer and Autoimmunity - Covers the complex relationship between the microbiome and the development, progression, and treatment of cancer and autoimmune diseases - Includes an analysis of the composition, diversity, and functions of microbial communities in influencing cancer and autoimmune conditions - Discusses how the microbiome influences immune responses, inflammation, and immune tolerance in the context of cancer and autoimmunity

Infection And Cancer Bi Directorial Interactions

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Author : Michael R. Shurin
language : en
Publisher: Springer
Release Date : 2015-11-02

Infection And Cancer Bi Directorial Interactions written by Michael R. Shurin and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-02 with Medical categories.

This unique book summarizes current knowledge on co-development of infectious diseases and cancer. It provides an overview of the complex and unique role of the immune system, inflammation, tumor-mediated immunosuppression and infection-induced immunomodulation in cancer and infection progression. Chapters are organized into themed parts, beginning with a look at the historical perspective of human tumor viruses, then aspects and examples of infection-related cancers and cancer-associated infections. The work discusses how cancer- and infection-associated immune responses interact in a bi-directorial fashion and how these interactions may evolve during both disease progression and in response to therapy. The phenomenon of independent development of cancer and infection in the same host, known as comorbid cancer-infection progression, is explored. Understanding the complex pathways involved in the progression of infection and cancer will allow the prevention of the development of certain types of cancer, as well as advancing prophylactic anti-cancer vaccines. Readers of this work will discover innovative approaches for multidisciplinary projects, focusing on the design of original therapeutic modalities for cancer therapy. The book will therefore be particularly valuable to scholars interested in cancer immunology and researchers and clinicians in the field of basic and applied immunobiology and microbiology.