Data Mining In Structural Biology
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Data Mining In Structural Biology
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Author : I. Schlichting
language : en
Publisher: Springer
Release Date : 2014-04-18
Data Mining In Structural Biology written by I. Schlichting and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-18 with Science categories.
Structural biology is becoming a routine technique for structure de termination in pharmaceutical industries. The advances in molecular biology, crystal handling and data collection techniques, tunable syn chrotron radiation sources, and high-performance computing have all contributed to developments such as the production and expression of tailored protein domains, the use of the MAD (Multiple Anomalous Dispersion) method, and the collection of X-ray data from tiny crystals at cryogenic temperature. The number of protein structures deposited in the Protein Databank has increased tremendously over the last 3-4 years. Since 1997, more than 1,500 structures have been deposited each year, and during the first 7 months of this year, 1,500 protein structures were already deposited. The numerous initiatives in the field of "structural genomics" distributed all over the world have led to the development of techniques for high-throughput structure determina tion, thereby contributing to the increase in the determination of three dimensional protein structures. This structural information is being ex plored in various ways in the drug discovery process. It is not only used in structure-based drug design of new low-molecular-weight li gands, but also in the early stages of target validation and assessment. With the number of protein sequences without significant homology to well-known proteins increasing, the technique of structure-sequence compatibility (threading) is increasingly used to assign a function to a given protein fold.
Data Mining In Structural Biology
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Author : I. Schlichting
language : en
Publisher: Springer
Release Date : 2001-05-15
Data Mining In Structural Biology written by I. Schlichting and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-05-15 with Science categories.
Structural biology is becoming a routine technique for structure de termination in pharmaceutical industries. The advances in molecular biology, crystal handling and data collection techniques, tunable syn chrotron radiation sources, and high-performance computing have all contributed to developments such as the production and expression of tailored protein domains, the use of the MAD (Multiple Anomalous Dispersion) method, and the collection of X-ray data from tiny crystals at cryogenic temperature. The number of protein structures deposited in the Protein Databank has increased tremendously over the last 3-4 years. Since 1997, more than 1,500 structures have been deposited each year, and during the first 7 months of this year, 1,500 protein structures were already deposited. The numerous initiatives in the field of "structural genomics" distributed all over the world have led to the development of techniques for high-throughput structure determina tion, thereby contributing to the increase in the determination of three dimensional protein structures. This structural information is being ex plored in various ways in the drug discovery process. It is not only used in structure-based drug design of new low-molecular-weight li gands, but also in the early stages of target validation and assessment. With the number of protein sequences without significant homology to well-known proteins increasing, the technique of structure-sequence compatibility (threading) is increasingly used to assign a function to a given protein fold.
Data Mining In Bioinformatics
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Author : Jason T. L. Wang
language : en
Publisher: Springer Science & Business Media
Release Date : 2005
Data Mining In Bioinformatics written by Jason T. L. Wang and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Computers categories.
Written especially for computer scientists, all necessary biology is explained. Presents new techniques on gene expression data mining, gene mapping for disease detection, and phylogenetic knowledge discovery.
Biological Data Mining
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Author : Jake Y. Chen
language : en
Publisher: CRC Press
Release Date : 2009-09-01
Biological Data Mining written by Jake Y. Chen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-01 with Computers categories.
Like a data-guzzling turbo engine, advanced data mining has been powering post-genome biological studies for two decades. Reflecting this growth, Biological Data Mining presents comprehensive data mining concepts, theories, and applications in current biological and medical research. Each chapter is written by a distinguished team of interdisciplin
Data Mining Techniques For The Life Sciences
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Author : Oliviero Carugo
language : en
Publisher: Humana
Release Date : 2023-05-19
Data Mining Techniques For The Life Sciences written by Oliviero Carugo and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-19 with Science categories.
This third edition details new and updated methods and protocols on important databases and data mining tools. Chapters guides readers through archives of macromolecular sequences and three-dimensional structures, databases of protein-protein interactions, methods for prediction conformational disorder, mutant thermodynamic stability, aggregation, and drug response. Quality of structural data and their release, soft mechanics applications in biology, and protein flexibility are considered, too, together with pan-genome analyses, rational drug combination screening and Omics Deep Mining. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials, includes step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Data Mining Techniques for the Life Sciences, Third Edition aims to be a practical guide to researches to help further their study in this field.
Data Mining In Structural Biology
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Author : I. Schlichting
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Data Mining In Structural Biology written by I. Schlichting and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.
Structural biology is becoming a routine technique for structure de termination in pharmaceutical industries. The advances in molecular biology, crystal handling and data collection techniques, tunable syn chrotron radiation sources, and high-performance computing have all contributed to developments such as the production and expression of tailored protein domains, the use of the MAD (Multiple Anomalous Dispersion) method, and the collection of X-ray data from tiny crystals at cryogenic temperature. The number of protein structures deposited in the Protein Databank has increased tremendously over the last 3-4 years. Since 1997, more than 1,500 structures have been deposited each year, and during the first 7 months of this year, 1,500 protein structures were already deposited. The numerous initiatives in the field of "structural genomics" distributed all over the world have led to the development of techniques for high-throughput structure determina tion, thereby contributing to the increase in the determination of three dimensional protein structures. This structural information is being ex plored in various ways in the drug discovery process. It is not only used in structure-based drug design of new low-molecular-weight li gands, but also in the early stages of target validation and assessment. With the number of protein sequences without significant homology to well-known proteins increasing, the technique of structure-sequence compatibility (threading) is increasingly used to assign a function to a given protein fold.
Data Mining For Bioinformatics
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Author : Sumeet Dua
language : en
Publisher: CRC Press
Release Date : 2012-11-06
Data Mining For Bioinformatics written by Sumeet Dua and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-06 with Computers categories.
Covering theory, algorithms, and methodologies, as well as data mining technologies, Data Mining for Bioinformatics provides a comprehensive discussion of data-intensive computations used in data mining with applications in bioinformatics. It supplies a broad, yet in-depth, overview of the application domains of data mining for bioinformatics to he
Biological Data Mining In Protein Interaction Networks
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Author : Li, Xiao-Li
language : en
Publisher: IGI Global
Release Date : 2009-05-31
Biological Data Mining In Protein Interaction Networks written by Li, Xiao-Li and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-31 with Technology & Engineering categories.
"The goal of this book is to disseminate research results and best practices from cross-disciplinary researchers and practitioners interested in, and working on bioinformatics, data mining, and proteomics"--Provided by publisher.
Data Mining In Biomedicine
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Author : Panos M. Pardalos
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-10
Data Mining In Biomedicine written by Panos M. Pardalos and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-10 with Medical categories.
This volume presents an extensive collection of contributions covering aspects of the exciting and important research field of data mining techniques in biomedicine. Coverage includes new approaches for the analysis of biomedical data; applications of data mining techniques to real-life problems in medical practice; comprehensive reviews of recent trends in the field. The book addresses incorporation of data mining in fundamental areas of biomedical research: genomics, proteomics, protein characterization, and neuroscience.
Data Mining In Medical And Biological Research
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Author : Eugenia Giannopoulou
language : en
Publisher: BoD – Books on Demand
Release Date : 2008-11-01
Data Mining In Medical And Biological Research written by Eugenia Giannopoulou and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-01 with Medical categories.
This book intends to bring together the most recent advances and applications of data mining research in the promising areas of medicine and biology from around the world. It consists of seventeen chapters, twelve related to medical research and five focused on the biological domain, which describe interesting applications, motivating progress and worthwhile results. We hope that the readers will benefit from this book and consider it as an excellent way to keep pace with the vast and diverse advances of new research efforts.