Decoding Checkpoint Inhibitor Induced Immune Related Adverse Events Volume Ii

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Decoding Checkpoint Inhibitor Induced Immune Related Adverse Events Volume Ii

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Author : Deborah L. Burnett
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-14

Decoding Checkpoint Inhibitor Induced Immune Related Adverse Events Volume Ii written by Deborah L. Burnett and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-14 with Medical categories.

Deciphering The Regulatory Role Of Transcription Factors In Cancer Immune Infiltration

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Author : Qian Yang
language : en
Publisher: Frontiers Media SA
Release Date : 2025-02-18

Deciphering The Regulatory Role Of Transcription Factors In Cancer Immune Infiltration written by Qian Yang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-18 with Medical categories.

Transcription factors (TF) are proteins that bind to specific DNA sequences and regulate the transcription of target genes. They control various cellular processes, including cell proliferation, differentiation, and immune responses. In cancer, dysregulated TF activity can profoundly impact the tumor microenvironment, influencing immune cell recruitment, activation, and function. By modulating the expression of immune-related genes, TFs can either promote or suppress immune infiltration in the tumor, shaping the anti-tumor immune response. Cancer immune infiltration, the process by which immune cells infiltrate tumor tissues, is a critical aspect of the tumor microenvironment and plays a pivotal role in cancer progression and response to therapy. Understanding the regulatory role of TFs in cancer immune infiltration holds significant promise for the development of novel therapeutic strategies and biomarkers for cancer treatment.

Advancements In Oral Cancer Modern Diagnostics Altered Molecular Profile And Therapeutic Strategies

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Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2025-07-16

Advancements In Oral Cancer Modern Diagnostics Altered Molecular Profile And Therapeutic Strategies written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-16 with Medical categories.

This compelling volume examines the evolving landscape of oral cancer research and treatment, providing critical insights into cutting-edge diagnostics, molecular alterations, and therapeutic advancements. With contributions from leading researchers and clinicians, the book presents a comprehensive, multidisciplinary perspective on oral oncology. Key chapters examine the role of salivary epigenetic biomarkers in early detection, the molecular reprogramming of histologically normal tissues adjacent to tumors, and the profound impact of cancer-associated fibroblasts on treatment response. The volume also explores the latest advancements in advanced radiotherapy techniques, including Intensity-Modulated Radiotherapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT), and evaluates outcomes and side effects with a focus on personalized treatment strategies. Importantly, the book addresses the microbial dysbiosis that arises after radiation therapy and its implications for the progression of oral cancer and patient quality of life. Whether you are a clinician, researcher, or healthcare professional, this volume serves as a valuable resource for understanding the molecular intricacies and therapeutic complexities of oral cancer. The book reflects the latest scientific advancements and underscores the importance of precision medicine and interdisciplinary collaboration in improving clinical outcomes for patients worldwide.

Systemic Immune Dysregulation In Malignant Disease Insights Monitoring And Therapeutic Exploitation

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Author : Petros Christopoulos
language : en
Publisher: Frontiers Media SA
Release Date :

Systemic Immune Dysregulation In Malignant Disease Insights Monitoring And Therapeutic Exploitation written by Petros Christopoulos and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.

Decipher Cellular And Molecular Mechanism Of The Development And Degeneration Of Functional Spinal Unit With Potential Therapeutic Approaches

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Author : Bo Gao
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-09

Decipher Cellular And Molecular Mechanism Of The Development And Degeneration Of Functional Spinal Unit With Potential Therapeutic Approaches written by Bo Gao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-09 with Science categories.

Aacr 2019 Proceedings Abstracts 2749 5314

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Author : American Association for Cancer Research
language : en
Publisher: Coe Truman International, LLC
Release Date : 2019-03-08

Aacr 2019 Proceedings Abstracts 2749 5314 written by American Association for Cancer Research and has been published by Coe Truman International, LLC this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-08 with categories.

American Association for Cancer Research 2019 Proceedings: Abstracts 2749-5314 - Part B

The Logic Of Immunity

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Author : Bobby Joseph Cherayil
language : en
Publisher: JHU Press
Release Date : 2024-01-23

The Logic Of Immunity written by Bobby Joseph Cherayil and has been published by JHU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-23 with Medical categories.

Unveils how the immune system works and explores strategies for harnessing its potential for maintaining good health. Embark on a fascinating journey into the human immune system with The Logic of Immunity. B. J. Cherayil, an accomplished immunologist and educator, demystifies the complex workings of our body's defense system. This scientifically grounded book illustrates the inner mechanisms of specialized cells and molecules that safeguard our health, shedding light on how and why our immune systems can malfunction and lead to disease. Drawing from years of experience and expertise, Dr. Cherayil skillfully guides readers through the intricacies of immune responses and offers invaluable insights into the latest research-backed strategies to harness their power for maintaining and restoring well-being. Blending scientific knowledge with historical anecdotes, this work also introduces the remarkable scientists who have shaped our understanding of immune function. Complemented by detailed illustrations and a glossary of key terms, The Logic of Immunity explains how the immune system interacts with other body systems, why some people develop autoimmune diseases while others do not, and how lifestyle factors may activate or suppress the immune system. Explore the enigmatic world of immunity, unlock its secrets, and discover the power it holds to protect our health.

Recent Advances In Cardiotoxicity Testing

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Author : Tamer M. A. Mohamed
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-05

Recent Advances In Cardiotoxicity Testing written by Tamer M. A. Mohamed and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-05 with Science categories.

Tumor Ablation And Immunity

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Author : Yueyong Xiao
language : en
Publisher: Frontiers Media SA
Release Date : 2024-02-29

Tumor Ablation And Immunity written by Yueyong Xiao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-29 with Medical categories.

Pemphigus And Pemphigoid Diseases In Memoriam Detlef Zillikens

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Author : Ralf J. Ludwig
language : en
Publisher: Frontiers Media SA
Release Date : 2024-06-19

Pemphigus And Pemphigoid Diseases In Memoriam Detlef Zillikens written by Ralf J. Ludwig and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-19 with Medical categories.

Pemphigus and pemphigoid diseases are a heterogenous group of autoimmune blistering disorders (AIBD) characterized by tissue-bound and circulating autoantibodies against structural proteins of the desmosome and basement membrane zone of the skin and orifice-close mucosal tissues. While strong evidence has been provided that autoantibodies in AIBD are pathogenic, the exact mechanisms of how blister formation is mediated is very different between pemphigus and pemphigoid disorders and yet incompletely understood. Additionally, target antigens for the major AIBDs have already been identified on the molecular level. In contrast, diagnostic assays are not yet available for all autoantibody specificities and isotypes. Treatment also greatly relies on long-term unspecific immunosuppressants, although rituximab has greatly improved the outcome for patients with moderate and severe pemphigus. There is currently still a need to identify key pathophysiological mediators and pathways for the development of more specific, safer, and more effective treatment options. This Research Topic will honor the work of the late Detlef Zillikens, who has dedicated over 30 years to the field of AIBD and has authored more than 600 articles. We strongly encourage the submission of articles from colleagues and researchers who have collaborated with Prof. Zillikens in the past, however, we will also consider manuscripts from other authors. We would particularly like articles to cite Prof. Zillikens work wherever it is appropriate. We welcome the submission of original research and review articles that cover, but are not limited to, the following sub-topics: • autoantibody specificities • diagnostic assays • in vitro or in vivo studies about the effect of autoantibodies and their modulation • epidemiology and treatment of AIBD Reports of individual cases are discouraged Dr. Enno Schmidt receives grant funding from Euroimmun, Incyte, Dompe, Admirx, Synthon/biondis, Bayer, Pharmix, Alpine Immune, AstraZeneca, Sanofi, ArgenX, UCB, Novartis, Biotest, Fresenius Medical Care, and is consulting for Roche, Imevax, Thermo Fisher, Janssen, Topas, Bristol-Myers Squibb, Almirall, and Chugai. The other Topic Editors declare no potential competing interests in relation to the Research Topic theme.