Delivering Nucleic Acids To Immune And Non Immune Cells

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Delivering Nucleic Acids To Immune And Non Immune Cells
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Author : Francesca Re
language : en
Publisher: Frontiers Media SA
Release Date : 2024-02-16
Delivering Nucleic Acids To Immune And Non Immune Cells written by Francesca Re and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-16 with Medical categories.
Drug Delivery And Targeting
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Author : Monika Schäfer-Korting
language : en
Publisher: Springer Nature
Release Date : 2024-03-29
Drug Delivery And Targeting written by Monika Schäfer-Korting and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-29 with Medical categories.
Since the publication of the Handbook of Experimental Pharmacology Vol. 197 in 2010 there have been important advances in drug development, drug delivery and – more recently – drug targeting. This is in particular relevant with the new generation of drugs acting on the immune system and tumors. These are quite often accompanied by major adverse reactions. Safe therapy is, therefore, an important area of research, in particular in chronic diseases and in persons of old age. In addition, the Covid-19 pandemic has brought renewed attention to vaccinations against viral infections, and mRNA vaccines have been tested for vaccination in tumor therapy, too. Vaccine delivery has stimulated important research on carriers which may pave the way for other applications and enhance a path to e.g. CRISPR-cas therapy.
Insights In Biomaterials 2022 2023 Novel Developments Current Challenges And Future Perspectives
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Author : Hasan Uludag
language : en
Publisher: Frontiers Media SA
Release Date : 2024-03-04
Insights In Biomaterials 2022 2023 Novel Developments Current Challenges And Future Perspectives written by Hasan Uludag and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-04 with Science categories.
Advances And Challenges In Nanomedicine
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Author : Susan Hua
language : en
Publisher: Frontiers Media SA
Release Date : 2019-02-28
Advances And Challenges In Nanomedicine written by Susan Hua and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-28 with categories.
Nanotechnology is a multidisciplinary field that is revolutionizing the way we detect and treat damage to the human body. Nanomedicine applies nanotechnology to highly specific medical interventions for the prevention, diagnosis, and treatment of diseases. They are increasingly being used to overcome biological barriers in the body to improve the way we deliver compounds to specific tissues and organs. In particular, nanomedicines have been shown to be beneficial for stabilizing therapeutic compounds, overcoming obstacles to cellular and tissue uptake, and improving biodistribution of compounds to target sites in vivo. Nanomedicines have demonstrated significant therapeutic advantages for a multitude of biomedical applications, however the clinical translation of these nanotechnology platforms has not progressed as quickly as the plethora of positive results would have suggested. Understanding the advances in nanomedicine to date and the challenges that still need to be overcome, will allow future research to improve on existing platforms and to address the current translational and regulatory limitations. This eBook “Advances and Challenges in Nanomedicine” has brought together experts in the fields of nanomedicine, nanotechnology, nanotoxicology, pharmaceutics, manufacturing, and translation to discuss the application of nanotechnology to drug delivery. This information is presented as original research, opinion, perspective, and review articles. The goal of this eBook is to generate collaborative discussion on the current status, general trends, challenges, strategies, and future direction of pharmaceutical nanotechnology, as well as highlight current and emerging nanoparticulate platforms with potential medical applications.
Rna Therapeutics
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Author : Paloma H. Giangrande
language : en
Publisher: Academic Press
Release Date : 2022-04-10
Rna Therapeutics written by Paloma H. Giangrande and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-10 with Science categories.
RNA Therapeutics: The Evolving Landscape of RNA Therapeutics provides a comprehensive overview of RNA therapeutic modalities, from bench-to-bedside, with an emphasis on the increasingly impactful areas of gene therapy, oligonucleotide therapeutics, gene editing and delivery. International leaders in the field examine RNA-based therapeutics tools that have been developed to-date to modulate cellular processes such as transcription, translation and protein function. Approved RNA-based therapies and lessons learned from failed therapies are discussed in-depth, as are evolving advances in RNA biochemical analysis, and similar advances that are enabling clinical application of RNA-based therapies. Later sections discuss delivery technologies, remaining hurdles in research and translation, the therapy development process from the lab to the clinic, and novel RNA-based therapies currently in development. - Features leading experts in the field of RNA therapeutics, spanning all classes of RNA therapies - Provides a detailed examination of approved RNA therapies and lessons learned from failed therapeutics - Covers all aspects of therapeutic discovery and preclinical development, as well as clinical translation, manufacturing and regulatory aspects
Biological Dna Sensor
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Author : Choon Kit Tang
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-10-30
Biological Dna Sensor written by Choon Kit Tang and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-30 with Medical categories.
In this chapter, we reflect on our early understanding of the immunogenic properties of dsDNA and give a chronological account of the journey we have taken to discover the individual cellular DNA sensors which have played important roles in mediating DNA induced inflammation.
Integrative Approaches To Biotechnology
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Author : Atul Bhargava
language : en
Publisher: CRC Press
Release Date : 2023-09-29
Integrative Approaches To Biotechnology written by Atul Bhargava and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-29 with Science categories.
Biotechnology is one of the fastest emerging fields that has attracted attention of conventional biologists, biochemists, microbiologists, medical and agricultural scientists. The coming decades are likely to witness a boom in biotechnology, which is expected to surpass information technology as the new engine of the global economy. Biotechnology is experiencing a revolution that will affect every facet of our lives, from crop improvement to commerce, drugs and sustainable development. New approaches and a plethora of information available at a frantic pace demands its dissemination to the scientific community. The current book has been written with the specific objective of providing information on the recent developments in biotechnology to the readers. The proposed book presents a multidisciplinary approach to the latest information and developments in biotechnology in an easy-to-read, succinct format. The book has been divided into 6 sections and 15 chapters giving an in-depth analysis of the latest research and developments in the biotechnological realm. The topics have been presented in a lucid, easy-to-read methodical way with illustrations and suitable case studies to provide additional help and clarity. The authors have tried to present state-of-the-art and integrative information in a manner that familiarizes the reader with the important concepts and tools of recent biotechnological studies. Apart from biotechnological personnel, the book would also be useful for readers of diverse disciplines such as bioinformatics, agriculture, environmental science, pharmaceutical sciences, biochemistry and general biology. Features A systematic overview of the recent state-of-the-art technologies. Novel contents with maximum coherence. Extensive use of examples and case studies to illustrate how each technique has been used in practice. Incorporation of the latest information on these topics from recent research papers. This book serves as a reference book and presents information in an accessible way for students, researchers and scientific investigators in biotechnology. It may also be used as a textbook for postgraduate-level courses in biological sciences.
Infection Inflammation Cardiovascular Diseases And Neurodegeneration
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Author : Deng-Feng Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-25
Infection Inflammation Cardiovascular Diseases And Neurodegeneration written by Deng-Feng Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-25 with Science categories.
Molecular Medicines For Cancer
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Author : Deepak Chitkara
language : en
Publisher: CRC Press
Release Date : 2018-09-03
Molecular Medicines For Cancer written by Deepak Chitkara and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with Medical categories.
The field of molecular medicine covers the medical interventions targeting molecular structures and mechanisms that are involved in disease progression. In cancer, several molecular mechanisms have been shown to impact its progression, aggressiveness and chemoresistance. Increasing evidence demonstrates the role of nanotechnology and outcome of molecular therapy. Several books have discussed molecular biology and mechanisms involved in cancer, but this text gives an account of molecular therapeutics in cancer relating to advancements of nanotechnology. It provides a description of the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology. Key Features: Provides current information in the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology Presents important aspects of nanotechnology in the site-specific delivery of anticancer agents Includes up to date information on oligonucleotide and gene based therapies in cancer Describes small targeted molecules, antibodies and oligonucleotides which have shown to selectively target the molecular structures thereby influencing signal transduction Facilitates discussion between researchers involved in cancer therapy and nanoscientists
Novel Antigen Delivery Approaches For Priming T Cell Mediated Immune Responses
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Author : Dirk Brockstedt
language : en
Publisher: Herbert Utz Verlag
Release Date : 1998
Novel Antigen Delivery Approaches For Priming T Cell Mediated Immune Responses written by Dirk Brockstedt and has been published by Herbert Utz Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.