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Dermal And Ocular Toxicology


Dermal And Ocular Toxicology
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Dermal And Ocular Toxicology


Dermal And Ocular Toxicology
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Author : David W. Hobson
language : en
Publisher: CRC Press
Release Date : 2020-11-26

Dermal And Ocular Toxicology written by David W. Hobson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-26 with Medical categories.


Dermal and Ocular Toxicology: Fundamentals and Methods is a procedurally-oriented volume of detailed methods and practical examples discussing the dermal and ocular aspects of toxicology. The book is divided into a dermal section and an ocular section. Each section begins with a chapter on the anatomy and physiology of each organ system and then progresses to more specialized chapters discussing such topics as the toxicological pathology of each system, state-of-the-art in vitro and in vivo evaluatory procedures, statistical considerations for test design and data interpretation, and the utilization of test findings. Test methods are provided for acute dermal exposure effects, dermal hypersensitivity and photoallergy assessment, dermal and ocular 0.pharmacokinetics, skin flap and skin grafting techniques, and in vitro alternative methods. This book can be used as an instructional text or as a sourcebook for practicing toxicologists, pharmacologists, industrial hygienists, occupational health professionals, and graduate students.



Dermal And Ocular Toxicology


Dermal And Ocular Toxicology
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AUDIOBOOK

Author : David W. Hobson
language : en
Publisher:
Release Date : 1989-09-01

Dermal And Ocular Toxicology written by David W. Hobson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-09-01 with categories.




Toxicology Of The Eye


Toxicology Of The Eye
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Author : W. Morton Grant
language : en
Publisher: Charles C Thomas Publisher
Release Date : 1993-01-01

Toxicology Of The Eye written by W. Morton Grant and has been published by Charles C Thomas Publisher this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-01-01 with Eye categories.


The purpose of this book is to present a synopsis of what is known about substances that have toxic properties injurious to the eyes, disturbing to vision, or affecting eyes in other unwanted ways. The coverage is truly comprehensive, encompassing local and systemic, acute and chronic, human and veterinary toxicology of the eye. The text summarizes mechanisms of injury, treatments, and other relevant knowledge for more than 3000 alphabetized substances - essentially all those on which public information is available. Also described are systemic side effects of ophthalmologic drugs, treatment of chemical burns of the eyes, and testing methods and species specificity for toxic effects on the eyes. Facilitating access to this prodigious amount of information is a large index that cross-references substances and effects, including numerous synonyms. This monumental work is a truly definitive text and a highly useful reference book that should be available to every ophthalmologist, emergency room, and medical library.



Principles And Practice Of Skin Toxicology


Principles And Practice Of Skin Toxicology
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Author : Robert Chilcott
language : en
Publisher: John Wiley & Sons
Release Date : 2008-07-31

Principles And Practice Of Skin Toxicology written by Robert Chilcott and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-31 with Science categories.


Written by authorities in the field, this book provides a “bottom up” approach to studying skin toxicology. Principles and Practice of Skin Toxicology clearly outlines basic concepts, cites historical and modern references and contains a dictionary for easy reference. The inclusion of global legislation and regulatory aspects on the topic makes this a comprehensive review for every practitioner, clinical researcher in industry and academia, and MSc and PhD student of toxicology. Different sections cover skin structure and function, principles and measurement of skin absorption, clinical aspects of dermal toxicity and in vitro alternatives. A section on regulatory and legislative aspects includes case studies from the UK that fulfill European Union and US FDA requirements. A glossary provides definitions of technical terms, and the chapters contain an introduction, learning boxes and summary section for ease of use. Includes a chapter on drug delivery through the skin. Addresses risk assessment: a key area for the interpretation of skin absorption data that is rarely covered.



Principles Of Toxicology


Principles Of Toxicology
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Author : Phillip L. Williams
language : en
Publisher: John Wiley & Sons
Release Date : 2003-10-10

Principles Of Toxicology written by Phillip L. Williams and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-10-10 with Science categories.


A fully updated and expanded edition of the bestselling guide on toxicology and its practical application The field of toxicology has grown enormously since Industrial Toxicology: Safety and Health Applications in the Workplace was first published in 1985. And while the original edition was hugely popular among occupational health professionals, the time is ripe to address toxic agents not only in the industrial setting but also in the environment at large. Renamed Principles of Toxicology: Environmental and Industrial Applications, this new edition provides health protection professionals as well as environmental scientists with precise, up-to-date, practical information on how to apply the science of toxicology in both the occupational and environmental setting. Through contributions from leading experts in diverse fields, Principles of Toxicology, Second Edition features: Clear explanations of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems Coverage of occupational medicine and epidemiological issues The manifestation of toxic agents such as metals, pesticides, organic solvents, and natural toxins Special emphasis on the evaluation and control of toxic hazards Specific case histories on applying risk assessment methods in the modern workplace Ample figures, references, and a comprehensive glossary of toxicological terms



Assessing Ocular Toxicology In Laboratory Animals


Assessing Ocular Toxicology In Laboratory Animals
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Author : Andrea B Weir
language : en
Publisher: Humana
Release Date : 2015-01-28

Assessing Ocular Toxicology In Laboratory Animals written by Andrea B Weir and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-28 with Medical categories.


Ocular toxicity is routinely assessed in toxicology studies conducted for regulatory purposes. Ocular anatomy and physiology and the assessment of ocular toxicity itself can be challenging to scientists involved in the safety assessment of pharmaceuticals, pesticides and other agents. Anatomical and physiological differences between species can impact the nature of ocular effects observed following intended or unintended exposure of ocular tissues to xenobiotics. Ocular Toxicity in Laboratory Animals provides a concise reference addressing ocular anatomy and physiology across species that will enhance the design and interpretation of toxicology studies conducted for regulatory purposes. The book provides an overview of routine and advanced techniques that are used to assess ocular toxicity including slit lamp biomicroscopy, indirect ophthalmoscopy, electrophysiology and imaging methods for the anterior and posterior segments of the eye. Additionally, the book defines the regulatory expectations for pharmaceuticals intended to treat ocular diseases and for other non-pharmaceutical regulated chemicals. With contributions from experts in the field, Ocular Toxicity in Laboratory Animals is an authoritative, accessible guide for toxicologists and other scientists involved in conducting toxicology studies for regulatory purposes and/or reviewing data from such studies.



Dermatotoxicology


Dermatotoxicology
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Author : Francis Nicholas Marzulli
language : en
Publisher:
Release Date : 1987

Dermatotoxicology written by Francis Nicholas Marzulli and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.


The most recent edition of the classic reference text contains 47 chapters on the mechanisms of toxicants on the skin, and related issues. The first part of the book provides background information and basic concepts of dermatotoxicology, and the second part covers methodologies employed to discern toxic effects. Some of the featured topics include: light induced dermal toxicity, problems associated with chronic occupational skin exposure to toxic chemicals, animal rights and animal research, and cosmetics safety. Annotation copyright by Book News, Inc., Portland, OR



Dermal And Ocular Toxicology


Dermal And Ocular Toxicology
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Author : David W. Hobson
language : en
Publisher: CRC Press
Release Date : 2020-11-25

Dermal And Ocular Toxicology written by David W. Hobson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-25 with Medical categories.


Dermal and Ocular Toxicology: Fundamentals and Methods is a procedurally-oriented volume of detailed methods and practical examples discussing the dermal and ocular aspects of toxicology. The book is divided into a dermal section and an ocular section. Each section begins with a chapter on the anatomy and physiology of each organ system and then progresses to more specialized chapters discussing such topics as the toxicological pathology of each system, state-of-the-art in vitro and in vivo evaluatory procedures, statistical considerations for test design and data interpretation, and the utilization of test findings. Test methods are provided for acute dermal exposure effects, dermal hypersensitivity and photoallergy assessment, dermal and ocular 0.pharmacokinetics, skin flap and skin grafting techniques, and in vitro alternative methods. This book can be used as an instructional text or as a sourcebook for practicing toxicologists, pharmacologists, industrial hygienists, occupational health professionals, and graduate students.



Clinical Ocular Toxicology


Clinical Ocular Toxicology
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Author : Frederick T. Fraunfelder
language : en
Publisher: Saunders
Release Date : 2008

Clinical Ocular Toxicology written by Frederick T. Fraunfelder and has been published by Saunders this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.


Written by international authorities in ocular toxicology, including the Founder of The National Registry of Drug-Induced Side Effects and its current Director, this essential resource provides the clinically relevant information you need to effectively diagnose and manage herbal, chemical, and drug-related ocular problems. Comprehensive coverage of all drugs' generic and trade drug names, primary uses, ocular and systemic side effects, and clinical significance make this book - like its best-selling predecessor, Drug-Induced Ocular Side Effects - the ideal reference for quick, on-the-spot consultation. Leaders in the field provide need-to-know information on all aspects of ocular toxicology-all in one concise reference. Data from the National Registry of Drug Induced Ocular Side-Effects (Casey Eye Institute, Portland, OR) and the World Health Organization (Uppsala, Sweden) help you recognize and avoid drug-induced ocular side effects. A highly templated format makes retrieval of essential knowledge quick and easy. A wealth of full-color photographs provide vivid, visual diagnostic guidance. The latest information on approved medications helps you stay up to date and provide state-of-the-art care. Extensive coverage of principles of therapy, ocular drug delivery, methods to evaluate drug-induced visual side effects, and the role of electrophysiology and psychophysics gives you the knowledge you need to manage any challenge in ocular toxicology Authoritative guidance on ocular drugs and their use in pregnancy helps you safely manage the unique needs of these patients. The inclusion of the WHO classification system helps you determine whether a particular side effect is certain, probable, or likely to occur.



Acute Toxicology Testing


Acute Toxicology Testing
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Author : Shayne C. Gad
language : en
Publisher:
Release Date : 1998

Acute Toxicology Testing written by Shayne C. Gad and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medical categories.


Introduction. Acute Toxicology Program: Study Design and Development. Tests for Dermal Irritation and Corrosion. Ocular Irritation Testing. Dermal Sensitization. Photosensitization/Phototoxicity. Lethality Testing. Safety Considerations for the Administration of Agents By the Parenteral Routes. Acute Systemic Toxicity Tests. Routes, Formulations, And Vehicles. Considerations Specific to Animal Test Models. Statistical Analysis for Acute Toxicology. Acute Inhalation. Problems and Issues. Appendices. Subject Index.